Клініко-патогенетичне обгрунтування комплексного лікування хронічних сальпінгоофоритів, поєднаних з фоновими захворюваннями шийки матки: Автореф. дис.

I?i?noa?noai ioi?iie caei?ia’y Oe?a?ie

Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao

EI?IOE* NA?OEAIA ?AI??AIA

OAeE 618. 11’12— 002:618.146-002]— 07-08-092.

EE?I?EI-IAOIAAIAOE*IA IAA?OIOOAAIIss

EIIIEAENIIAI E?EOAAIIss

O?II?*IEO NAEUeI?IAIIOI?EO?A.

II?AeIAIEO C OIIIAEIE CAOAI?THAAIIssIE

OEEEE IAOEE

14.01.01 — aeooa?noai oa a?iaeieia?y

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Oa?e?a

1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia o Aei?i?iiao?ianuee?e aea?aeaai?e iaaee/i?e aeaaeai??
IIC Oe?a?ie

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe, i?ioani? Aeoainna?nueea
C?ia?aea Ieoaee?aia, Aei?i?iiao?ianueea Aea?aeaaia iaaee/ia aeaaeai?y,
caa?aeoaa/ eaoaae?e aeooa?noaa, a?iaeieia?? oa ia??iaoieia?? oaeoeueoaoo
i?neyaeeieiiii? ina?oe, caneoaeaiee ae?y/ iaoee oa oaoi?ee Oe?a?ie.

Io?oe?ei? iiiiaioe:

— aeieoi? iaaee/ieo iaoe, i?ioani? Eioaiaae/ ?aaai?y A?eoi??aia,
Ee?anueea aea?aeaaia iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i. I. E.
Ooieea, caa?aeoaa/ eaoaae?e aeooa?noaa oa a?iaeieia??;

— aeieoi? iaaee/ieo iaoe, i?ioani? A?euaiei Ieueaa Aaeaioei?aia,
Oa?e?anueea aea?aeaaia iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe,
caa?aeoaa/ eaoaae?e ia??iaoieia?? oa a?iaeieia??.

— aeieoi? iaaee/ieo iaoe, i?ioani? Aiaaeaoeei Ieeiea A?eai?iae/ ,
Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao, i?ioani? eaoaae?e
aeooa?noaa oa a?iaeieia?? ?2

I?ia?aeia onoaiiaa:

?inoeooo iaae?ao???, aeooa?noaa ? a?iaeieia??’ AII Oe?a?ie,
aeooa?nueei-a?iaeieia?/iee a?aeae?e,

i. Ee?a.

Caoeno a?aeaoaeaoueny “27” n?/iy 2000 ?. i 13-30 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee

Ae 64.600.01. i?e Oa?e?anueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? ca
aae?anith:

61022, Oe?a?ia, i. Oa?e?a, i?. Eai?ia, 4.

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (61022, Oe?a?ia, i. Oa?e?a, i?.
Eai?ia, 4).

Aaoi?aoa?ao ?ic?neaiee “ 27 ” a?oaeiy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

eaiaeeaeao iaaee/ieo iaoe, aeioeaio I. I. Oaiueei

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Ca inoaii? aeanyoe??//y iaeiie/aii aaeeeee
oaeoe/iee iaoa??ae c ieoaiiy a?noio?c?ieia?? ? iaoieia?? oeeee iaoee
(OI), a?aeia?aaeai? o no/anieo eeaneo?eaoe?yo caoai?thaaiue ae?ii/eo
noaoaaeo i?aai?a, o I?aeia?iaei?e iiiaieeaoo?? oai?ia (IIO) oii V???
(caoai?thaaiiy ae?ii/i? noaoaai? nenoaie, 1992), o I?aeia?iaei?e
noaoenoe/i?e eeaneo?eaoe?? oai?ia (INEO) V ia?aaeyaeo ? o A?noieia?/i?e
eeaneo?eaoe?? iooeei (AEI) ae?ii/i? noaoaai? nenoaie, 2-a ?aaeaeoe?y
(1994).

Iaea?eueo iiaia ??ciiiai?oia iaoieia?y oeeee iaoee (OI) iaaaaeaia o
?iaioao Eioaiaae/ A.A. (1997, 1998), Eiiae??eiaa I.?. (1997, 1998),
?onaeaae/ I.N. (1998), o yeeo a?aoiao?oueny ia eeoa no/aniee noai
iaoeiaeo aeine?aeaeaiue c aeaiiai ieoaiiy, a e i?noeoueny caeeee aei
i?aeoe/ii? ioi?iie caei?ia’y a?aeiiaeoeny a?ae canoa??eeo iaeiaioaaiue ?
oa?i?i?a a?coaeueiiai iieno ci?i OI ? iaiao?aeiino? i???ioe?o ia aeai?
eieueii- ? oea?a?eineii??.

O nenoai? i?io?eaeoe/ieo caoiae?a, ni?yiiaaieo ia ai?ioueao c ?aeii OI,
e?eoaaiiy oiiiaeo ? ia?aae?aeiaeo caoai?thaaiue caeia? iaeia c ia?oeo
i?noeue (Aaneeaanueea E.I. ? ni?aaao. (1987), I?eeainueea A.I. (1987).
Aaaeeea?noue ieoaiiy iaoiiaeaia aenieith /anoioith oeeo caoai?thaaiue,
iaaeinoaoiueith aoaeoeai?noth e?eoaaiiy, a oaeiae iaaiith ?iia??i?noth
?o ia?a?iaeaeaiiy (Eica/aiei A.I., 1997).

Ca inoaii?e /an ?ic?iaeaii ? ai?iaaaeaeaii o ee?i?/io i?aeoeeo aaeeeo
e?euee?noue ??ciiiai?oieo iaoiae?a e?eoaaiiy caoai?thaaiue OI, ye? /anoi
anioe?ththoueny c o?ii?/iei caiaeaiiyi aeiaeaoe?a iaoee, eiaeai c yeeo
ia? iieacaiiy aei canoinoaaiiy, ia?aaaae e iaaeie?ee, oa?aeoa?eco?oueny
iaaiei a?aenioeii oneeaaeiaiue (No?oaaoeueeee A.I., 1997; Einoaaa I.I.,
1997), (Hillard et al, 1996), i?ioa ni?iae ?ic?iaeoe oi?aa?naeueiee
iaoiae ia oa?i/aeeny oni?oii.

Aeua neacaia noaei i?aenoaaith aeey ?ic?iaee iaoiaeieia?/ieo aniaeo?a
oe??? i?iaeaie, ooi/iaiiy aoaiiino? e?eoaaeueii-?aaa?e?oaoe?eii?
i?ia?aie o oai?eo c oiiiaeie caoai?thaaiiyie oeeee iaoee (OCOI), ye?
ii?aeiothoueny c o?ii?/iei naeuei?iaiioi?eoii (ONI) ? oi?ioaaiiy
ioe?ii/ieo e?eoa???a ?eceeo aeieeiaiiy oe??? iaoieia?? o
?iciianthaeaeaiiai eiioeiaaioo a?iaeieia?/ieo oai?eo aeey ?aaeueii?
i?io?eaeoeee a?coaeueieo oi?i ?aeo aai?oae?e, /ei ? aoea i?iaeeeoiaaia
iaiao?aei?noue iaoiai aeine?aeaeaiiy.

Ne?ae a?aei?oeoe, ui aeacai? ieoaiiy aoee a?aeianai? aei i?ei?eoaoieo ia
O c’?cae? aeooa??a-a?iaeieia?a Oe?a?ie (1996) ? ia OV? anana?oiueiio
eiia?an? aeooa??a-a?iaeieia?a o Aeai?? (Eiiaiaaaai, 1997).

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. ?iaioa iia’ycaia
c aeeiiaiiyi iaoeiai-aeine?aeieoeueei? ?iaioe ia eaoaae?? aeooa?noaa,
a?iaeieia?? oa ia?eiaoieia?? Aei?i?iiao?ianueei? aea?aeaaii? iaaee/ii?
aeaaeai?? ? Aea?ae?a?no?aoe?? 1970009374: «Iaoeiaa iaa?oiooaaiiy nenoaie
caoiae?a ii iie?auaiith noaio caei?ia’y, cieaeaiith caoai?thaaiino? ?
nia?oiino? iaoa??a oa ae?oae Oe?a?ie.»

Iaoa aeine?aeaeaiiy. ?ic?iaea iaoeiaeo iniia i?iaiicoaaiiy, i?io?eaeoeee
? e?eoaaiiy OCOI, ii?aeiaieo c ONI, c o?aooaaiiyi noaio aiaeie?eiieo
ni?aa?aeiioaiue, i?e?ia?ioeaiico noaoaaeo oeyo?a ae?iee, iieiia?ea??a
aeey cieaeaiiy a?coaeueieo oi?i ?aeo.

Caaea/? aeine?aeaeaiiy:

1. I?iaanoe ee?i?ei-noaoenoe/ia aeine?aeaeaiiy aeey aea/aiiy
aca?iica’yceo i?ae OCOI o oai?eo c o?eaaeei o?ii?/iei caiaeaiiyi
aeiaeaoe?a iaoee, ci?iith noaio aiaeie?eiiiai aiiainoaco, o?eaae?noth ?
aoaii?noth i?iaaaeaiiy eiiieaenii? i?ioecaiaeueii? oa?ai??.

2. Ooi/ieoe ?ieue ? i?noea CINO, ye? iae/ano?oa cono??/athoueny o
aeieeiaii? OCOI i?e ONI.

3. Aea/eoe ooieoe?iiaeueiee noai aiaeie?eiii? nenoaie o oai?eo c OCOI ?
o?eaaeeie caiaeaiiyie aeiaeaoe?a iaoee.

4. Noi?ioaaoe ioe?ii? e?eoa??? ?eceeo aeieeiaiiy OCOI c o?aooaaiiyi
oi?iaeueiino? iieiia?ea??a.

5. ?ic?iaeoe ? ee?i?/ii ai?iaoaaoe nenoaio i?aai?caoe?eii-i?io?eaeoe/ieo
caoiae?a ? e?eoaaeueio oaeoeeo (?c canoinoaaiiyi eaca?ii? oa?ai??
iecueeiaia?aaoe/iei eaca?ii) aeey iaoiaaiaoe/ii? ei?aeoe?? i?e OCOI ?
noiooiueiio ONI.

Iaoeiaa iiaecia. ?noioiith iiaeciith a?aecia/a?oueny cai?iiiiiaaiee iaie
iiaee aa??aio iaoiaeieia?/iiai aniaeoo aeine?aeaeaiue o oai?eo ?c
niieo/aieie aeia?iye?nieie caoai?thaaiiyie aai?oae?e (NAeCA), ui
aeeth/athoue no/ani? ae?aaiinoe/i? oaoiieia?? o a?iaeieia??
(eieueiioea?a?eineii?th, ?ioiiioa?iaioiee, ?aae?i?ioiiee aiae?c,
aecia/aiiy iieiia?ea??a), ye? aeicaieythoue i?iaiicoaaoe iaaaoeai?
iane?aeee oe??? iaoieia??, ui i?eaiaeeoue aei aeieeiaiiy
iieicaoai?thaaiue.

Oia?oa eiiieaenii i?iaiae?ciaai? ioe?ii? e?eoa??? ?eceeo aeieeiaiiy OCOI
? cai?iiiiiaai? aeey ee?i?/ii? i?aeoeee no/ani?, i?aeoiaee e?eoaaiiy,
ye? aaciina?aaeiuei aieeaathoue ia iaoieia?/ia na?aaeiaeua, ia
aieeaathoue ia iieiaaiac (eaca?ioa?ai?y, i?aia?aoe nieeiaaa?i,
nieeio?eoiaae), a oaeiae eiiieaen e?eoaaeueii-?aaa?e?oaoe?eii? i?ia?aie
aeey ii?iae?caoe?? ii?ooaiiy iae?iaiaeie?eiieo ni?aa?aeiioaiue.

Iaie noai?aia i?ea?iaeueia eiii’thoa?ia i?ia?aia aeey ?ic?iaee
?iaeea?aeoaeueii? iiaeae? i?iaiico, ?aoeeaeea?a caiaeaiiy aai?oae?e,
OCOI ? i?io?eaeoe/ieo caoiae?a o ?iciianthaeaeaiiai eiioeiaaioo
a?iaeieia?/ieo oai?eo, aeey cieaeaiiy /anoioe ceiye?nieo iiaiooai?aiue
ae?ii/eo noaoaaeo i?aai?a.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a. Io?eiai? ?acoeueoaoe
aeicaieeee ia iniia? ee?i?ei-noaoenoe/ieo aeine?aeaeaiue noai?eoe
eiioeaiooaeueio iiaeaeue iniaeeainoae NAeCA o ae?iie I?eaei?i?ianueeiai
?aa?iio c o?aooaaiiyi iniaeeainoae ai?iiiaeueiiai aiiainoaco,
naenoaeueii? iiaaae?iee, ??ciiiai?oieo oi?i canoiniaaiiai e?eoaaiiy;
anoaiiaeoe ao?ieia?/io cia/ei?noue CIIO (oeai?ae?ico, aa?aeia?aeaco,
o?iaai?oaeueiiai eaiae?aeii?eico) o aeieeiaii? OCOI i?e ?o niieo/aii? c
ONI;

aia?oa aeieacaii, ui ii?iae?caoe?y iae?iaiaeie?eiieo ni?aa?aeiioaiue ?c
canoinoaaiiyi iaai?iiiaeueieo iaoiae?a aieeao aeicaiey? aeinyaoe
aenieiai oa?aiaaoe/iiai aoaeoo, ui ?aaeueii cieaeo? ?ecee aeieeiaiiy
a?coaeueieo oi?i ?aeo ? ia? iaaeeei-nioe?aeueiee aoaeo; aeieacaii, ui
iaiao?aeia eiiieaenia e?eoaaiiy iaio noaoaaeo ia?oia??a ia oii?
aa?’??-oa?ai?? aei ii?iae?caoe?? i?e?ia?ioeaiico na/inoaoaaiai o?aeoo,
ui aeicaiey? aeinyaoe aoaeoeaiino? cai?iiiiiaaii? iaie iiaeae?
e?eoaaeueii-i?io?eaeoe/ii? i?ia?aie.

Iaoiaee ianoaaeaiiy ? cai?iiiiiaai? iaoiaee i?iaiicoaaiiy, i?io?eaeoeea
? e?eoaaiiy oai?eo c OCOI ? noiooi?i ONI ai?iaaaeaeai? o i?aeoeeo
Iiaiiineianueeiai oa?eoi??aeueiiai iaaee/iiai ia’?aeiaiiy (aieiaiee
e?ea? A.N. Aooa?ia), IN* o?oaiiai caaiaeo I.Iiaiiineianueea,
Aei?i?iiao?ianueeiai ee?i?/iiai i?nueeiai iieiaiaiai aoaeeieo ?2
(aieiaiee e?ea? E.?. Iaaeaeei). Io?eiai? o ?acoeueoao? aeeiiaiiy ?iaioe
iaoa??aee aeei?enoiaothoueny o iaaeaaia?/iiio i?ioean? eaoaae?e
aeooa?noaa, a?iaeieia?? ? ia?eiaoieia?? oa eaoaae?e aeooa?noaa oa
a?iaeieia?? iaaee/iiai oaeoeueoaoo AeAeIA.

Iniaenoee aianie caeiaoaa/a. Aaoi? iniaenoi i?iaiae?coaaa ye aieiaiee
aeooa?-a?iaeieia i.Iiaiiineianueea iieacieee yeino? a?iaeieia?/ii?
aeiiiiiae ae?ieai i.Iiaiiineianueea ca 1996-1998 ??., iniaenoi ianoaaeea
? aea/ea ?acoeueoaoe ianoaaeaiiy 120 ae?iie c OCOI niieo/aieie c ONI, 20
i?aeoe/ii caei?iaeo ae?iie, ye? neeaee eiio?ieueio a?oio, aeine?aeea
io?eiai? ?acoeueoaoe.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iaoa??aee aeine?aeaeaiue
aeieeaaeaeeny ia iaoeiai-i?aeoe/ieo can?aeaiiyo anioe?aoe??
aeooa??a-a?iaeieia?a Aei?i?iiao?ianueei? iaeano? (1997, 1998, 1999 ??.),
a oaeiae ia Ieaioiao I?aae?iiy Oe?a?inueei? anioe?aoe??
aeooa??a-a?iaeieia?a (1997,1998??.), iaoeia?e nan?? Aei?i?iiao?ianueei?
AeIA (1997, 1998 ??.).

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 7 ?ia?o, c ieo 3 o
oaoiaeo aeaeaiiyo Oe?a?ie.

Ianya oa no?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 180
noi??ieao iaoeiiieno ? neeaaea?oueny c anooio, iaeyaeo e?oa?aoo?e, 5
?icae?e?a aeanieo aeine?aeaeaiue, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e,
ia?ae?eo e?oa?aoo?e. ?iaioa ?ethno?iaaia 8 iaethieaie oa 10 oaaeeoeyie,
ui caeiathoue 18 noi??iie.

INIIAIEE CI?NO ?IAIOE

Iaoa??aee ? iaoiaee aeine?aeaeaiiy. O a?aeiia?aeiino? c caaaeaiiyie
aeine?aeaeaiue aoei ianoaaeaii 120 ae?iie ?c OCOI ? ONI, oa 20 caei?iaeo
ae?iie ?c caa?aaeaiith iaino?oaeueiith ? ?ai?iaeoeoeaiith ooieoe??th.

Oai??, ye? ciaoiaeeeenue i?ae iaaeyaeii, i?aeaeaeeny iiaeeaeaiiio
ee?i?/iiio ianoaaeaiith c aeaoaeueiei aea/aiiyi niaaeeiaino?,
caaaeueiiai ? niaoe?aeueiiai aiaiiaco ia?aianaieo ?ioaeoe?eieo,
niiaoe/ieo ? a?iaeieia?/ieo caoai?thaaiue.

Ca aeiiiiiaith i?ia?aiiiai iaoaiaoe/iiai aiae?co ?c cia/ii? e?eueeino?
aiaiianoe/ieo ? ee?i?/ieo aeaieo aoee aeae?eai? ? ioa?aeoa?eciaai?
iaea?eueo cia/i? oaeoi?e ?eceeo ?icaeoeo OCOI.

On?i oai?ei i?iaiaeeee caaaeueiiee?i?/i? ianoaaeaiiy, ai?iaaaeaeai? a
no/ani?e a?iaeieia?/i?e ee?i?oe?: aeine?aeaeaiiy caaaeueiiai aiae?co
e?ia? ? na/?, e?ia? ia RW ? A?E, Hbs Ang aaeoa??ieia?/ia,
aaeoa??ineii?/ia oa ?ioiioa?iaioia aeine?aeaeaiiy aiaeioea?a?eaeueiiai
ai?noo, o?ao?e, e?ia? ca aeiiiiiaith aiae?caoi?a AAAIO (NOA), iin?a na/?
ia noa?eeuei?noue, eae ia aeenaaeoa??ic.

On?i oai?ei o aeeiai?oe? ianoaaeaiiy aoei i?iaaaeaii oeueo?acaoeiaa
aeine?aeaeaiiy ia aia?ao? «AEIEA»-630 aai?oae?e, ueoiaeaeii? caeice,
ia/?iee, ie?ie.

Ie?aii aecia/eee iooeeiiee ia?ea? Na-19-9 iaoiaeii ?OA ca aeiiiiiaith
iaai??a o NI «Ae?a — iethn».

Ooieoe?iiaeueio aeoeai?noue noaoaaeo caeic, iaaeie?iee?a ? noaio
aiiaaeio?iiii? ?aaoeyoe?? ioe?ithaaee ii ai?noo noa?i?aeieo ai?iii?a ?
aiiaaeio?ii?i?a o ne?iaaooe? e?ia?, aecia/ath/e ?o ?aae?i?ioiieia?/iei
iaoiaeii ?c aeei?enoaiiyi noaiaea?oieo iaai??a o??ie I?inuee
(A?ei?on?y). Anueiai c?iaeaii 869 aeine?aeaeaiue ai?iii?a iaoiaeii
?aae?i?ioiiiai aiae?co.

Aea/aee eiioeaio?aoe?th a e?ia? aiiaaeio?iiieo, noa?i?aeieo ai?iii?a ?
?o ni?aa?aeiioaiiy a aeeiai?oe? iaino?oaeueiiai oeeeeo: EA, ONA,
i?ieaeoei, ano?aae?ie, i?iaanoa?ii, ei?oecie, ano?aae?ie/i?iaanoa?ii,
ano?aae?ie/ei?oecie, ano?aae?ie/oanoinoa?ii, i?iaanoa?ii/oanoinoa?ii.

Oa?aeoa?enoeea aiaeie?eiiiai aiiainoaco ae?iie eiio?ieueii? a?oie
i?eaaaeaia o oaae.1.

?acoeueoaoe aeine?aeaeaiue o eiaei?e a?oi? oai?eo ia?iaeaii
aa??aoe?eii-noaoenoe/iei iaoiaeii c aecia/aiiyi aeinoia??iino?
?acoeueoao?a ca O?oa?ii-Nouethaeaioii (TH.E. Eaaiia, I.I. Iiai?aethe,
1990).

Oaaeeoey 1.

EIIOeAIO?AOe?ss A E?IA? AIIAAeIO?IIIEO,

NOA?I?AeIEO AI?III?A ? ?O NI?AA?AeIIOAIIss

A AeEIAI?Oe? IAINO?OAEUeIIAI OeEEEO O CAeI?IAEO AE?IIE

Ai?iiie Aeeiai?ea aeine?aeaeaiiy

aei? oeeeeo

6-10 13-15 20-24

EA iea/e 2,93±0,331 9,20±0,721 3,18±0,351

ONA iea/e 4,39±0,302 8,01±0,782 1,86±0,232

I?IEAEOEI iea/e 9,96±0,703 10,96±1,013 10,00±0,863

ANO?AAe?IE iiieue/e 343,61±24,154 1250,16±38,644 510,63±17,364

I?IAANOA?II iiieue/e 2,21±0,185 6,22±0,365 21,56±1,385

EI?OECIE iiieue/e 193,79±18,976 223,81±19,866 231,56±17,016

ANO?AAe?IE/

I?IAANOA?II 162,84±31,127 200,99±29,317 231,56±17,017

ANO?AAe?IE/

EI?OECIE 1,77±0,218 5,58±0,418 2,21±0,188

ANO?AAe?IE/

OANOINOA?II 327,24±42,619 603,94±32,269 276,02±29,689

EI?OECIE/

OANOINOA?II 209,74±32,8710 113,13±13,1710 128,57±9,6810

I?IAANOA?II/

OANOINOA?II 2,03±0,2711 3,00±0,4911 1,65±1,2911

I?ei?oea: (?) – a??ia?aei?noue ?ic??ciaiue

I. 1 – ? – 1:2<0,001; 2:3<0,001 II. 2 – ? – 1:(2,3)<0,01; 2:3<0,001 III. 3 – ? – ia cia/eii ?<0,05 IV. 4 – ? – 1:(2,3)<0,01; 2:3<0,001 V. 5 – ? – 1:(2,3)<0,01; 2:3<0,001 VI. 6 – ? – ia cia/eii ?<0,05 VII. 7 – ? – 1:3<0,001; 2:3<0,001 VIII. 8 – ? – 1:(2,3)<0,01; 2:3<0,001 IX. 9 – ? – 1:(2,3)<0,001; 2:3<0,02 X. 10 – ? – 1:2<0,02 XI. 11 – ? – 1:2<0,01; 1:3<0,01; 2:3<0,01 ?ACOEUeOAOE AeINE?AeAEAIUe ? ?O IAAIAI?AIIss Aeey ae??oaiiy iinoaaeaieo caaea/ iaie ianoaaeaii 120 ae?iie c ??cieie aa??aioaie ONI ? OCOI. Aiae?coth/e io?eiai? ?acoeueoaoe a iniiai?e a?oi?, ie c?iaeee aeniiaie, ui iaai? OCOI anioe?ththoueny c eiie?aoieie aa??aioaie ONI. ?c o?aooaaiiyi aiaiianoe/ieo, ee?i?/ieo ? eaai?aoi?ieo aeaieo an? oai?? aoee ?iciiae?eai? ia o?e ee?i?/i? a?oie: ? a?oia - oai?? c a?ia?ieanoe/ieie oiiiaeie i?ioeanaie oeeee iaoee (aiaeioea?a?eic, noaai?oae?aeueiee aiaeiiao??ic) ? ?oaoeaai-niaeeiaith oi?iith ONI (n= 45); II a?oia - oai?? c ?aoeeaeeaoth/ith oi?iith ONI ? OCOI (?noeiia a?ic?y oa aiaeioea?a?oeeoe) (n=43); III a?oia - 32 oai?? c ia?aeiiio?ii?/iith oi?iith ONI oa iinoo?aaiaoe/ieie ?ic?eaaie OI ? aeo?ii?iiii. Aeyaeai? i?e eieueiineii?? oa a?noieia?/iiio ianoaaeaii? OCOI eeaneo?eoaaee a?aeiia?aeii aei eeaneo?eaoe?? ?.A. sseiaeaai? oa A.O. Eoaooa (1997). Eiiieaen cai?iiiiiaaieo iaie iaoiae?a ianoaaeaiiy aeaa iiaeeea?noue aea/eoe aca?iica’ycie aiaeie?eiii? nenoaie c a?coaeueieie ? oeeoieia?/ieie iciaeaie ii?iaeueieo ia?aiao??a OI, ui iiaeiii aooe i?eeiyoei aei oaaae i?e oi?ioaaii? a?oi ?eceeo OCOI, /anoi niieo/aieo c ONI, ui i?eaiaeyoue aai aei aacie?aeaey, aai aei ?aeo OI. Aiae?coth/e ?ioi?iaoe?eio cia/ou?noue 14 aeae?eaieo iaie oaeoi??a ?eceeo, ie iaea?aeaee a a?aenioeao eiia??i?noue caoai?thaaiiy a eiaeiiio eiie?aoiiio aeiaaeeo. Oea aeaei ciiao noai?eoe ?aaeueio nenoaio i?iaiico OCOI ia aoai? ae?ii/i? eiinoeueoaoe?? OII i. Iiaiiineianueea ? cieceoe a?aenioie a?coaeueieo oi?i ?aeo aai?oae?e (oaae. 2). Oaaeeoey 2 OAEOI?E ?ECEEO ?ICAEOEO OCOI Oaeoi?e ?eceeo ?ioi?iaoe?eia cia/ei?noue oaeoi?o o % 1. Noai OI aei 1-? aaa?oiino? 17 2. Iieiaiaa o?aaia 15 3. E?euee?noue iieia?a, a?eueoa 2-o 12 4. *enei aaa?oiinoae, a?eueoa 4-o 10 5. Iaia?oa o 15 ?ie?a ? noa?oa 7 6. A?iaeieia?/ia iaoieia?y 6 7. Niiaoe/ia iaoieia?y 5 Oeai?ae?ic 6 A?a??i?/i? iaaeee ae?iie 7 Aeae?eaiiy c noaoaaeo oeyo?a 4 A?e a?ae 27 ?ie?a ? noa?oa 2 Ia?aianaiee niaoeeo?/iee i?ioean 2 Ii?ooaiiy IOe aei ii/aoeo noaoaaiai aeeooy 1 Niaaeeiaa noeeuei?noue 11 Aeei?enoaiiy a aeeiai?oe? cai?iiiiiaaiiai iaie ae?aaiinoe/iiai eiiieaeno aeicaieeei nai?/anii aeyaeyoe i?ia?anoth/ee ia?ao?ae OCOI a aeenieanoe/i? i?ioeane ? ci?ithaaoe oaeoeeo iaaeyaeo ca oai?ith. Io?eiai? iaie aeai? aiae?co oaeoi??a ?eceeo aeieeiaiiy OCOI aeoaea aaaeeea? o ee?i?/i?e i?aeoeoe? ? iiaeii? a?aoiaoaaoenue e?ea?ai aeooa?ii-a?iaeieiaii ye aeiiiaiaiiy aei iaeaco ?192 IIC Oe?a?ie: oea icaei?iaeaiiy OCOI aei aaa?oiino? ? ieaioaaiiy eiaeii? aaa?oiino? i?ney ooi/iaiiy e?eoa???a caei?iai? oeeee iaoee; /?oea iiiiaeaiiy oe?einoiino? i’yeeo iieiaiaeo oeyo?a, iniaeeai OI i?e iieiaao; /enei aaa?oiinoae ? iieia?a; iaia’yceiaa aeio?eiaiiy i?aaee iniaenoi? a?a??ie iaio noaoaaeo ia?oia??a; iaoiaaiaoe/ia e?eoaaiiy o iaio ia?oia??a ?ioaeoe?e, ye? ia?aaeathoueny noaoaaei oeyoii aei ii/aoeo aaa?oiino?. Aeey iie?ioaiiy oaeoeee e?eoaaiiy oai?eo OCOI iaie a?aoiaoaaeeny i?yi? (i?ae iieacieeaie noa?i?aeieo ai?iii?a ? eieueiineii?/iith ea?oeiith) ? cai?ioi? (i?ae oe?ai?aeieie ai?iiiaie ? oeeoieia?/iith ea?oeiith) ei?aeyoe?ei? ca’ycee. I?e ?o a?aenooiino? oai?ei c OCOI c neaaeith aeenieac??th OI aeioe?eueii i?iaiaeeoe eiina?aaoeaia e?eoaaiiy (i?noeaaa i?ioecaiaeueia, ?ioiioa?ai?y, canoinoaaiiy nieei-o?eoiaaeo, nieeiaaa?io) ia oii? aeeoa?aioe?eiaaii? ?iaeea?aeoaeueii? iaoiaaiaoe/ii? oa?ai?? ONI. Oey i?iaeaia, iniaeeai o a?aeiioaii? aei ae?iie oa?oeeueiiai a?eo, ? aein? ia ae??oaia. Aeiaaaeaii, ui aeoii?y OI – oea ai?iiiicaeaaeia caoai?thaaiiy, iaeiae, iaoai?ci ?? iaoiaaiaca /?oei ia aecia/aiee. A?aeiii, ui i?ae oeee?iae?e/iei ai?oae??i aeoi- ? aiaeioea?a?eno, aaciina?aaeiuei iaae aacaeueiith iaia?aiith, ciaoiaeeoueny ?yae oae caaieo ?aca?aieo ee?oei, ye? iiaeooue aeeoa?aioe?thaaoenue a aaaaoioa?iaee ieineee ai?oae?e i?ae ae??th ano?iaai?a. Iaa?ae’?iiith oiiaith oeueiai i?ioeano iiaeiii aooe ?oeioaaiiy ee?oei oeee?iae?e/iiai ai?oae?th. No/ani? iaoiaee e?eoaaiiy iaeiaoaeoeai? o iieiaeeo ae?iie, ye? ia ia?iaeaeoaaee. Oae? iaoiaee, ye aeano?oeoe?y (ae?aoa?iieiaaoeyoe?y ? e??ioa?ai?y) i?ecaiaeyoue aei ?oeioaaiiy ia o?eueee oeee?iae?e/iiai ai?oae?th, aea ? ?aca?aieo ee?oei. Aeei?enoaiiy o?i?/ieo eiaaoeyio?a (nieeia?i, aaaio?e) ia caaaeaee aea? iioeiaeueio eiaaoeyoe?th a?iceaii? iiaa?oi?, niinoa??aathoueny ?aoeeaeeae caoai?thaaiiy o 29%. O ca’yceo c oeei, ua iaeiei caaaeaiiyi iaoiai aeine?aeaeaiiy aoei aea/aiiy ia o?eueee ai?iiiaeueieo ii?ooaiue oai?eo NAeCA, aea e ?ic?iaea uaaey/i? iaoiaeeee e?eoaaiiy. E?eoaaiiy oai?eo ? a?oie, ye? no?aaeaeaee ?oaoeaai-niaeeiaith oi?iith ONI oa a?ia?ieanoe/ieie OCOI aeeth/aei: oeueo?acaoeiaee aieea o ?iioeueniiio ?aaeei?; i?e aiiaoeyoi?ieo oeeeeao – aeaeo?ioi?ac nieae oeeieo oa i?ae?; i?e a?iiooieoe?? y?/iee?a – a?ycae?eoaaiiy. ?? aoai e?eoaaiiy caeeth/aany o i?ecia/aii? ?ioiiei?eaoth/eo caoiae?a: eaoa?ii oa ?ioiioa?ii, a oaeiae ?ioiinoeioeyoi?e ?c ?ineei (?ioiae, eiaeoae, ao?iioeay eiiiiceooi N oa ?i.). Ia?aeaeueii i?ecia/aeenue aaeaioiaaie o ?? oaco IOe – iano?e caiaieoe, ?iae?iee ?iaeaai? oa ?i. I?e iaiao?aeiino? i?ecia/aee aeeoa?aioe?eiaaio ai?iiiioa?ai?th. O oai?eo c noaai?oae?aeueiei aiaeiiao??icii ai?iiiioa?ai?y (aeaiie, aeaiiaae, aeaiiaeaeao, "/eno?" aanoaaaie) aoea aaciaith, i?ae eiio?ieai ai?iiiaeueieo ia?aiao??a, c iine?aeoth/ith o??o?a?/iith naiaoe??th aiaeiiao??ico. Oai?? c aiaeioea?a?eicii o a?oe? a?ae 22 aei 32 ?ie?a, c ia?aae?ciaaiith ?ai?iaeoeoeaiith ooieoe??th ? ii?ooaiiyi ai?iiiaeueieo ni?aa?aeiioaiue iaea?aeoaaee e?eoaaiiy ano?iaai-aanoaaaiieie i?aia?aoaie c iecueeei ai?noii ano?iaai?a (eiaano, i?e?iaaiii, ?eaaa?aeii, o?eea?ea?), i?ney /iai ia 8-10 aeaiue IOe i?iaiaeeee aeeoa?aioe?eiaaia e?eoaaiiy: i?e i?ie?oa?oth/iio aiaeioea?a?eic? – aeaeo?ieii?caoe?th, i?e noaoe?iia?iiio – nieeiaaa?i, iecueei?ioaineaio eaca?ioa?ai?th. O 47% oai?eo niinoa??aaeanue /anoeiaa ai?oae?caoe?y ae?eyiee aeoii??, a o 63% - iiaia ai?oae?caoe?y. O ?? ee?i?/i?e a?oi? (oea?a?oeeo ? ONI) iniaeeaino? iieyaaee a oiio, ui o eiaeii? o?aouei? ae?iee aecia/ai? CIIO, iniaeeai /anoi – oeai?ae?ic (53%), aoea aeniea /anoioa ae?eyiie aeno?aaai?oaeueii? ?ioaeoe??, o?ii?/ia ?aoeeaeeaoth/a i?io?eaiiy caiaeueiiai i?ioeano, ui iio?aaoaaei i?iaaaeaiiy aeeoa?aioe?aeueii? ae?aaiinoeee ?noeiii? a?ic?? OI ? aiaeioea?a?oeeoo. Eiiieaenia e?eoaaiiy o oai?eo ?? a?oie c ONI ?aoeeaeeaoth/ith oi?iith anioe?eiaaiith c caiaeueieie OCOI (?noeiia a?ic?y, aiaeioea?a?oeeo) ii/eiaee c i?ecia/aiiy aioeaaeoa??aeueii? oa?ai?? oa i?ioea??onii? oa?ai??. Aei eiiieaenii? oa?ai?? oai?eo oe??? a?oie aeeth/aee aia?aoio o?c?ioa?ai?th, aia?a?th iecueeiaia?aaoe/iiai aae?e-iaiiiaiai eaca?a. Aoaeo a?ae i?iaaaeaiiai e?eoaaiiy aoa iiceoeaiei o 96% aeiaaee?a. Oaaeeoey 3. I?E?IA?IOeAIIC NOAOAAEO OEssO?A O OAI?EO ?? EE?I?*II? A?OIE (a %) I?e?ii?aai?cie Oa?aeoa? iaoieia?/ieo ci?i ?noeiia a?ic?y O?ii?/iee oea?a?oeeo (i=33) i=10 OI aac iciae?a aeaoi?iaoe?? OI c iciaeaie aeaoi?iaoe?? i=11 i=22 1. Oeai?ae?? 23,8 27,6 3,2 2. O?aaieacie 31 32,8 4,6 3. Annioeeaoe?? oeai?ae?e c o?aaieaciaie, a??onii i?inoiai aa?iano oeio II 21,3 27,9 28,9 4. Oeeoiiaaaeia??on 3,6 14,9 18,6 5. Eieiaa oei?a 96,5 82,9 73,8 6. B.Mobiluncus 40 - 9,8 7. Ae??aeaeaeaiiae?ai? a?eae 39,5 45,5 38,5 8. Aa?aeia?aee 63,4 42 53,8 9. Eaeoiaaeoa??? 12,6 48 61,7 A caeaaeiino? a?ae ao?ieia?? i?e?iaiiai oaeoi?o oai?ei c aiaeioea?a?oeeoii canoiniaoaaee: eeio?eiacie, a?iiiaaa??e, iaei??i?-oi?oa, a?iaea?i, ee?ii-Ae. An?i oai?ei c aiaeioea?a?oeeoii i?iaiaeeee eaca?ioa?ai?th aae?e-iaiiiaei eaca?ii, i?aeaiaey/e na?oeiaiae aei iaoieia?/ii? ae?eyiee. Aoei a?aei?/aii 100-a?aenioeiaee iiceoeaiee aoaeo o oe??? a?oie oai?eo – ai?oae?caoe?th iaoieia?/ii? ae?eyiee OI, anoaiiaeaiiy ?ai?iaeoeoeaii? ooieoe?? o 46,8%. O aeaieo oai?eo aoee a?aei?/ai? iaie ci?ie oeaio?aeueii? ?aaoeyoe?? ooieoe?? y?/iee?a (a?iiano?iaaiai?y, a?iii?iaanoa?iiai?y), ui i?iyaeyeiny ii?ooaiiyi aacaeueii? ? oeeee?/ii? nae?aoe?? EA ? ONA ? aoei iniaeeai iaaeyaeii ae?aaeaii a iiiaio i/?eoaaii? iaoeyoe??. O 66% aeiaaee?a o oeeo oai?eo aeyaeaia aeenooieoe?y ueoiaeaeii? caeice. Ee?i?ei-iaoiaaiaoe/i? iniaeeaino? ??? a?oie (ONI ? iinoo?aaiaoe/i? OCOI) i?iyaeyeenue o aaaeeeaeo ci?iao i?e?ia?ioeaiico noaoaaeo oeyo?a (i?enoeoeueoo?e o 63,7%), i?e/iio nooiai? iinoo?aaiaoe/ii? ci?ie OI ei?aethaaeeny c o?eaae?noth ? iaaoaeoeai?noth e?eoaaiiy ia?aeiii-o?ii?/iiai ONI. A?aenooi?noue "o?c?ieia?/iiai caoai?o", yeei ? aiaoii?/ia OI, i?eaiaeeoue aei iaaoaeoeaiino? e?eoaaiiy. Aeine?aeaeaiiy aiaeie?eiiiai aiiainoaco aeyaeee cia/i? ii?ooaiiy oie?eoei- ? noa?i?aeiaaiaco a y?/ieeao, ui iicia/aeiny ii?ooaiiyi ni?aa?aeiioaiue ai?iii?a, a oaeiae ? ueoiaeaeii? caeice. Oea iaoiiaeei iaiao?aei?noue i?iaaaeaiiy ?iaeea?aeoaeueii? ai?iiiioa?ai?? (aeey ei?aeoe?? ooieoe?? ueoiaeaeii? caeice, a oaeiae eiia?iiaai? ano?iaai- aanoiaaii? i?aia?aoe). I?e eieueiineii?/iiio ianoaaeaii? i?oaiai? /anoeie aeaoi?iiaaii? OI a?aei?/aeanue aeoii?y c ciiith o?ainoi?iaoe??, aai o?eueee ciia o?ainoi?iaoe??. Aeyaeai? i?yi? ei?aeyoe?ei? ca’ycee i?ae cieaeaiiyi ??aiy ano?aae?ieo ? Na-19-9 (r=+0,62, P<0,05) ? cai?ioi?e ca’ycie i?ae ai?noii i?ieaeoeio ? Na-19-9 (r=-0,86, P<0,05). Eiiieaenia e?eoaaiiy ??? a?oie oai?eo c ia?aeiii-o?ii?/iith oi?iith ONI ? iinoo?aaiaoe/ieie OCOI ii/eiaee c i?aia?ao?a, ye? noeioeththoue ??ci? eaiee ?ioi?oaoo: eaaai?cie, i?iaeea?icai. I?e ??ceiae?aaeaiiio caaino?aii? i?ioeano i?iaiaeeee aioeaaeoa??aeueio oa?ai?th; i?ecia/aee o?c?ioa?ai?th, a?oai?ie a?oie N, A. Ae?oaee aoai aeeth/aa eo?n ?ioa?oa?iio, i?ney /iai i?ecia/aee aioeaa?aaaioe: eiiieai?i, oaii?eie. Aeey noeioeyoe?? nenoaie ?ai?iaeoeoe?? i?ecia/aee n??eiaiaeiaa? aaie ? c?iooaaiiy ii iaoiaeeoe? OeIAe? eo?i?oieia?? ? o?c?ioa?ai??. Iaie ?ic?iaeaia e?eoaaeueia o??o?a?/ia oaeoeea iinoo?aaiaoe/ii? aeaoi?iaoe?? oeeee iaoee oa aeo?ii?iio. Ie i?iaiaeeee o??o?a?/io ei?aeoe?th OI ?aeiino?oeoeaii-ieanoe/ieie iia?aoe?yie: aeaeo?ieii?caoe???, ii Aiaoo, ?eueoeiao-No?aeeiao A.?. oa Ni??iia?e O.A. i?ney ? aoaio i?ioecaiaeueii? oa?ai?? I?ney ieanoe/ieo iia?aoe?e iie?aueany neeaae i?oaiai? oei?e a a?e ca?eueoaiiy /enea eaeoiaaeoa??e. Aiae?c ai?noo iieiia?ea?o Na-19-9 a ia?eoa?e/i?e e?ia? o oai?eo c OCOI iieacaa, ui eiai ae?aaiinoe/ia cia/aiiy iiaeia a?aoiaoaaoe o?eueee a eiiieaen? c ?ioeie ae?aaiinoe/ieie oaoiieia?yie. AENIIAEE Nenoaia ioe?iieo e?eoa???a ?eceeo aeieeiaiiy OCOI aeicaieeea ooi/ieoe iaea?eueo oeiiaa ii?aeiaiiy aeia?iye?nieo caoai?thaaiue aai?oae?e: ?oaoeaai-niaeeiaa oi?ia ONI oa aiaeioea?a?eic, aai noaai?oae?aeueiee aiaeiiao??ic; ?aoeeaeeaoth/ee naeuei?iaiioi??o oa ?noeia a?ic?y OI aai aiaeioea?a?oeeo; ia?aeiii o?ii?/ia oi?ia ONI oa i?neyo?aaiaoe/i? OCOI, ui aeicaieeei iioei?coaaoe e?eoaaeueii-?aaa?e?oaoe?eio i?ia?aio oa cieceoe a?aenioie caiouaieo a?coaeueieo oi?i iieiiaoieia??. I?ae ni?aa?aeiioaiiyie iieaciee?a aiaeie?eiiiai aiiainoaco, eieueiineii?/ieie, oeeoieia?/ieie oa?aeoa?enoeeaie noaio OI, ia?aiao?aie i?e?ia?ioeaiico i?oae, cia/aiiyi iieiia?ea?a Na-19-9 aeyaeai? iaoiaaiaoe/i? aca?iia?aeiineie, ye? oa?aeoa?ecothoue ia o?eueee ee?i?/i? i?iyae OCOI, aea e iiaeooue i?iaiicoaaoe ?ecee ?o aeieeiaiiy. Aca?iica’ycie aiiaaeio?iiieo, noa?i?aeieo ? o??ai?aeieo ai?iii?a c ee?i?ei-eieueiineii?/ieie, oeeoieia?/ieie ia?aeaeyie, iieacieeaie i?e?ia?ioeaiico noaoaaeo oeyo?a a aeeiai?oe? ii?iaeueiiai iaoeyoi?iiai IOe oa?aeoa?eco?oueny aecia/aiith iiaeaeeth ei?aeyoeaieo ca’yce?a i?ae oeeoia?aiith, ??aiai iieiia?ea?a Na19-9 ? ai?iiiaeueieie ni?aa?aeiioaiiyie, yea aecia/a? i?io?eaeoeeo OCOI. Aaiethoe?y i?e?iaiiai oaeoi?o aecia/eea aeeaae aeayeeo CIIO, ianaiia?aae oeai?ae?e, a??on?a o caaacia/aii? ia?nenoaioe?? ?ioaeoe?? aai?oae?e ? /anoiai ii?aeiaiiy (72-75%) ONI c OCOI. I?e ?oaoeaai-niaeeia?e oi?i? ONI, ii?aeiaiiai c a?ia?ieanoe/ieie OCOI (aiaeioea?a?eic, noaai?oae?aeueiee aiaeiiao??ic) aeieeathoue eiie?aoi? eieueii- oeeoi- a?noieia?/i? oa?aeoa?enoeee a aeeiai?oe? IOe, ye iane?aeie ci?i EA, OA, i?iaanoa?iio ? aeiaaathoue ?iaeea?aeoaeueii? e?eoaaeueii? oaeoeee. I?e ?aoeeaeeaoth/?e oi?i? ONI, ii?aeiaiiio c ?noeiith a?ic??th OI ? aiaeioea?a?oeeoii ? a 67% c CIIO, aeieea? aeeaieee aeeniiain i?ae aca?iica’yceaie noa?i?aeieo ? oe?ai?aeieo ai?iii?a, ye? aecia/athoue o 82% oai?eo aeeno?io?/i? ci?ie a ai?oae?aeueieo ee?oeiao, ae?aaeaio e?ioioeeoa?io ?io?eueo?aoe?th c aeii?oeaie ieaciaoe/ieo ee?oei a?no?ioeeo?a i?e a?noieia?/iiio aeine?aeaeaii? OI. O iaoe??ioie c ia?aeiii-o?ii?/iith oi?iith ONI ? iinoo?aaiaoe/ieie OCOI, ye iane?aeie /anoeo iieiaiaeo o?aai (a 29% aeiaaee?a ia oii? o?c?ieia?/ii? aeoii??) aeieeathoue ci?ie aiaeie?eiiiai aiiainoaco, /ano?oa a?iio?c-o??ai?aeii? nenoaie, aecia/athoueny oeiia? eieueiineii?/i?, oeeoi-a?noieia?/i? ia?aiao?e (oanoii/aoee oa?aeoa? ciai?oiueiai eiioo?o ciie aeoii??, caeaaei?noue aenioe i?eciaoe/iiai ai?oae?th a?ae oace IOe, aaeeea e?euee?noue oa?i?iaeueieo noaeei a i?aeeaae?e c’?aeioaaeuei?e oeaiei?). A o?aaeeoe?eia iaoiaaiaoe/ia e?eoaaiiy NAeAC iaiao?aeii aeeth/aoe e??i aaeaioiaai?a, ?ioiinoeioeyoi??a, ai?iii?a, aioea?ioee?a aeeoa?aioe?eiaaiee i?aeo?ae aeey aieeao ia ci?iaio OI: eaca?ioa?ai?th, e??iaeano?oeoe?th, ?aeino?oeoeaii-ieanoe/i? iia?aoe??, ui ni?eythoue ii?iae?caoe?? aiaoiii-ooieoe?iiaeueieo ci?i a OI. Aeai?eoi ae?e e?ea?y, ?aaeaiaiooth/ee oi?ioaaiiy ? aeeniaina?iee iaaeyae a?oi i?aeaeuaiiai ?eceeo oai?eo c aeia?iye?nieie ii?aeiaiiyie caoai?thaaiue aai?oae?e (ONI, OCOI), ye? /anoi i?eaiaeyoue aei iieiiaoieia??, aeiaaa? ?icoe?aiiy ae?aaiinoe/iiai eiiieaeno (aecia/aiiy i?e?ia?ioeaiico noaoaaeo oeyo?a, ?icoe?aio eieueiioea?a?eineii?th, i?e iaiao?aeiino? a?noieia?/ieo aeine?aeaeaiue, ai?iiiaeueieo ni?aa?aeiioaiue), ui aeicaieeoue ia o?eueee eiie?aoecoaaoe iicieia?/io oi?io OCOI, aea e iioei?co? e?eoaaeueii-?aaa?e?oaoe?eio i?ia?aio. NIENIE ?IA?O, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe??. Ei?ioe/ N.?. Oi?ioaaiiy ioe?ii/ieo e?eoa???a ?eceeo aeieeiaiiy oiiiaeo caoai?thaaiue oeeee iaoee // Iaae?ao??y, aeooa?noai oa a?iaeieia?y. – 199. - ?2. – N. 105-107. Ei?ioe/ N.?. E?eoaaeueia oaeoeea aeoii?e oeeee iaoee ae?iie, ye? ia ia?iaeaeoaaee // Iaaee/i? ia?niaeoeae. – Aei-nuee. – 1999. – o. I. - ?2. Ei?ioe/ N.?. Ii?aeiai? aeia?iye?ni? caoai?thaaiiy aai?oae?e: ae?aaiinoeea oa e?eoaaiiy // Iaae?ao??y, aeooa?noai oa a?iaeieia?y. – 1999. - ?2. – N. 107-109. Ei?ioe/ N.?., I?ey?a A.A. Ninoiyiea o?iiaioeeoa?iiai caaia nenoaiu aiiainoaca o aieueiuo o?iie/aneei ?aoeeaeeae?othuei naeueieiaiioi?eoii. A ei. Nia?aiaiiua i?iaeaiu eeeie/aneie e yenia?eiaioaeueiie iaaeeoeeiu. – Aei-ne. – 1994. – N. 122-123. Aeoainna?neay C.I., Ei?ioe/ N.A. Aii?inu iaoiaaiaca na?aea/ii-ninoaeenouo ?anno?ienoa o aeaiuei oa?oeeueiiai aic?anoa n ia?ooaieai ?ai?iaeoeoeaiie ooieoeee. A ei. I?aoe? VI i?ae?aa?iiaeueii? iaoeiai-i?aeoe/ii? eiioa?aioe?? aiae?ieia?a oa naeniiaoieia?a. – Aei-ne. – 1995. – N.104-107. Aeoainna?neay C.I., Ei?ioe/ N.A. Iaoieiaey yiaeiiao?ey o aieueiuo a ?ai?iaeoeoeaiii aic?anoa. – A ei. I?aoe? VI i?ae?aa?iiaeueii? iaoeiai-i?aeoe/ii? eiioa?aioe?? aiae?ieia?a oa naeniiaoieia?a. – Aei-ne. – 1995. – N. 101-104. Aeoainna?neay C.I., I?eeiae A.A., Ei?ioe/ N.A. Ninoiyiea yiaeie?eiiiai aiiainoaca i?e iaaeiiioaiiie aa?aiaiiinoe. – A ei. I?aoe? VI i?ae?aa?iiaeueii? iaoeiai-i?aeoe/ii? eiioa?aioe?? aiae?ieia?a oa naeniiaoieia?a. – Aei-ne. – 1995. – N. 114-116. AIIOAOe?ss Ei?ioe/ N.?. Ee?i?ei-iaoiaaiaoe/ia iaa?oiooaaiiy eiiieaeniiai e?eoaaiiy o?ii?/ieo naeuei?iaiioi?eo?a, ii?aeiaieo c oiiiaeie caoai?thaaiiyie oeeee iaoee. – ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.01. – aeooa?noai oa a?iaeieia?y. – Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao. Oa?e?a, 2000. Aeena?oaoe?y i?enay/aia ?ic?iaoe? iaoeiaeo iniia i?iaiicoaaiiy, i?io?eaeoeee ? e?eoaaiiy OCOI ii?aeiaieo c ONI c o?aooaaiiyi noaio aiaeie?eiieo ni?aa?aeiioaiue, i?e?ia?ioeaiico noaoaaeo oeyo?a ae?iee, iieiia?ea??a, eieueiineii?/ii? oa a?noieia?/ii? oa?aeoa?enoee aeey cieaeaiiy a?coaeueieo oi?i ?aeo. A i?ioean? ?iaioe aaoi?aie noai?aia i?ea?iaeueia eiii’thoa?ia i?ia?aia aeey ?ic?iaee ?iaeea?aeoaeueii? iiaeae? i?iaiicoaaiiy ?aoeeaeea?a caiaeaiiy aai?oae?e, OCOI ? i?io?eaeoe/ieo caoiae?a aeey cieaeaiiy /anoioe ceiye?nieo iiaiooai?aiue OI. Aia?oa eiiieaenii i?iaiae?ciaai? ioe?ii? e?eoa??? ?eceeo aeieeiaiiy OCOI ? cai?iiiiiaai? aeey ee?i?/ii? i?aeoeee no/ani? i?aeoiaee e?eoaaiiy, ye? aaciina?aaeiuei aieeaathoue ia iaoieia?/ia na?aaeiaeua, ia aieeaathoue ia iieiaaiac, a oaeiae eiiieaen e?eoaaeueii-?aaa?e?oaoe?eii? i?ia?aie aeey ii?iae?coaaiiy ii?ooaiue iae?iaiaeie?eiieo ni?aa?aeiioaiue. Eeth/ia? neiaa: OCOI, ONI, eieueiioea?a?eineii?y, eiii’thoa?ia i?ia?aia ?iaeea?aeoaeueiiai i?iaiicoaaiiy, iieiia?ea?e. AIIIOAOeEss Ei?ioe/ N.A. Eeeieei-iaoiaaiaoe/aneia iainiiaaiea eiiieaeniiai ea/aiey o?iie/aneeo naeueieiaiioi?eoia, ni/aoathueony n oiiiauie caaieaaaieyie oaeee iaoee. – ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.01. – aeooa?noai e aeiaeieiaey. – Oa?ueeianeee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao, Oa?ueeia, 2000. Aeenna?oaoeey iinayuaia ?ac?aaioea iao/iuo iniia i?iaiice?iaaiey, i?ioeeaeoeee e ea/aiey OCOI, ni/aoathueony n ONI n o/aoii ninoiyiey yiaeie?eiiuo niioiioaiee, iee?iaeioeaiica iieiauo iooae aeaiueiu, iieiia?ea?ia, eieueiineiie/aneie e aenoieiae/aneie oa?aeoa?enoee aeey nieaeaiey aecoaeueiuo oi?i ?aea. A i?ioeanna ?aaiou nicaeaia i?eaeiaeueiay eiiiuethoa?iay i?ia?aiia aeey ?ac?aaioee eiaeeaeaeoaeueiie iiaeaee i?iaiice?iaaiey ?aoeeaeeaia ainiaeaiey aaieoaeee, OCOI e i?ioeeaeoe/aneeo ia? aeey nieaeaiey /anoiou ceiea/anoaaiiuo iiaiia?aciaaiee OI. Nenoaia ioeaii/iuo e?eoa?eaa ?enea aicieeiiaaiey OCOI iicaieeea ooi/ieoue iaeaieaa oeie/iua ni/aoaiey aeia?iea/anoaaiiuo caaieaaaiee aaieoaeee: ?oaoeiai-niaa/iay oi?ia o?iie/aneiai naeueieiaiioi?eoa e yiaeioea?aeeic eee noayieoaeeaeueiue yiaeiiao?eic; ?aoeeaeeae?othuee naeueieiaiioi?eo e enoeiiay y?icey oaeee iaoee eee yiaeioea?aeoeeo; ia?ae/ii-o?iie/aneay oi?ia naeueieiaiioi?eoa a ni/aoaiee n iinoo?aaiaoe/aneeie OCOI, /oi iicaieeei iioeiece?iaaoue ea/aaii-?aaaeeeoaoeeiiioth i?ia?aiio e nieceoue i?ioeaio caiouaiiuo aecoaeueiuo oi?i iieiiaoieiaee. Onoaiiaeaiu iaoiaaiaoe/aneea acaeiiioiioaiey iaaeaeo niioiioaieai iieacaoaeae yiaeie?eiiiai aiiainoaca, eieueiineiie/aneeie oeeoieiae/aneeie oa?aeoa?enoeeaie ninoiyiey OI, ia?aiao?aie iee?iaeioeaiica aeaaaeeua, cia/aieai iieiia?ea?a Na-19-9, eioi?ua oa?aeoa?ecotho ia oieueei eeeie/aneea i?iyaeaiey OCOI, ii e iiaoo i?iaiice?iaaoue ?ene eo aicieeiiaaiey. Aia?aua eiiieaenii i?iaiaeece?iaaiu ioeaii/iua e?eoa?ee ?enea aicieeiiaaiey OCOI e i?aaeeiaeaiu aeey eeeie/aneie i?aeoeee nia?aiaiiua iiaeoiaeu e ea/aieth, eioi?ua ia aeeytho ia iieiaaiac, a oaeaea eiiieaen ea/aaii-?aaaeeeoaoeeiiiuo i?ia?aii aeey ii?iaeecaoeee ia?ooaiee iae?iyiaeie?eiiuo niioiioaiee. Eeth/aaua neiaa: OCOI, ONI, eieueiioea?aeeineiiey, eiiiuethoa?iay i?ia?aiia eiaeeaeaeoaeueiiai i?iaiice?iaaiey, iieiia?ea?u. SUMMARY Korotich S.Y. Clinic-pathogenetic ground of complex treatment of chronic salphingophorits which combines with background diseases of the cervix of the uterus. – manuscript. Thesis for a Candidate degree of medicine in speciality 14.01.01. obstetrics and gynecology. Kharkiv State Medical University, Kharkiv, 2000. Thesis is devoted to elaboration of scientific foundation of prophylaxis prognostication and treatment of background diseases of the cervix of the uterus united with chronic saphingophorits taking into account condition of endocrine correlation of microbiocenosis of sexual passages of the woman genitals oncomarcers, colposcopical and histological descriptions for reducing of visual form of cancer. Key words. The background diseases of the cervix of the uterus. Chronic salphingophorits. The computer programme of individual prognostication. Colpocervicoscopia. PAGE PAGE 3

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