Характер цитогенетичних пошкоджень у дітей, які мешкають на територіях, забруднених радіоактивними опадами внаслідок аварії на Чорнобильській АЕС: Авт

2

OE?A?INUeEEE IAOEIAEE A?A??I?*IEE OeAIO?

AeEANUeEA Ieaia Ai?en?aia

OAeE: 576.312.32.38:612.014.482

oa?aeoa? oeeoiaaiaoe/Ieo IIOEIAeAEAIUe o ae?oae, ssE? IAOEATHOUe ia
oa?eoi??yo, Caa?oaeiaieo ?aae?iaeoeaieie iiaaeaie aiane?aeie AAA??? IA
*I?IIAEEUeNUeE?E AAN.

03.00.15 — aaiaoeea

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa
a?ieia?/ieo iaoe

Ee?a – 1998

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a ?inoeooo? aenia?eiaioaeueii? ?aae?ieia?? Iaoeiaiai
oeaio?o ?aae?aoe?eii? iaaeeoeeie AII Oe?a?ie

Iaoeiaee ea??aiee:

Aeieoi? iaaee/ieo iaoe, n. i. n. I?e?inueea Ia??y Aiae???aia, Iaoeiaee
oeaio? ?aae?aoe?eii? iaaeeoeeie, caa?aeoth/a eaai?aoi???th.

Io?oe?ei? iiiiaioe:

Aeieoi? a?ieia?/ieo iaoe, aeioeaio Ai?iaa Aeea ?aai?aia, ?inoeooo
i?iaeai i?e?iaeiei?enooaaiiy oa aeieia?? IAI Oe?a?ie, caa?aeoth/a
a?aeae?eii.

Eaiaeeaeao iaaee/ieo iaoe, E?aa/oe Ieaenaiae? Iaaeiae/, ?inoeooo
aeia?a??ie oa oien?eieia?? ?i. E.?.Iaaeaaaey IIC Oe?a?ie, caa?aeoth/ee
eaai?aoi???th.

I?ia?aeia onoaiiaa:Iaoe?iiaeueiee oi?aa?neoao ?iai? Oa?ana Oaa/aiea,
eaoaae?a caaaeueii? ? iieaeoey?ii? aaiaoeee, I?i?noa?noai ina?oe
Oe?a?ie, i. Ee?a

Caoeno aeena?oaoe?? a?aeaoaeaoueny » 17 » a?oaeiy 1998 ?. i 10-00
aiaeei? ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.604.01 a
Oe?a?inueeiio iaoeiaiio a?a??i?/iiio oeaio?? ca aae?anith: 253660,
Ee?a-94, aoe. Iiioae?aiea, 50

C aeena?oaoe??th iiaeia iciaeiieoenue a a?ae?ioaoe? Oe?a?inueeiai
iaoeiaiai a?a??i?/iiai oeaio?o: i.Ee?a, aoe. Iiioae?aiea, 50

Aaoi?aoa?ao ?ic?neaiee » 6 » eenoiiaaea 1998 a.

A/aiee nae?aoa?niaoe?ae?ciaaii? a/aii? ?aaee, Naeaciueia A.TH.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie

A?aoiaoth/e niaoeeo?eo ?aae?aoe?eii? neooaoe??, ui neeaeany a Oe?a?i? a
?acoeueoao? aaa??? ia *i?iiaeeuenuee?e AAN, iniaeeao aeooaeuei?noue
iaaoei aecia/aiiy i?neyaaa??eiiai ??aiy oeeoiaaiaoe/ieo iieaciee?a o
ethaeeie ye a?aeaoeo ?aaeoeaiino? i?aai?cio aei iooaaaiieo oaeoi??a
?aae?aoe?eii? i?e?iaee oa iiaeeeaiai e?eoa??th ioe?iee iiaeeiooi? aeice
?ii?coth/iai ii?ii?iaiiy.

sse aiaeiii, iaeaieueo iioe?aiei, aeia?a ai?iaiaaiei oa aeinoaoiuei
ei?aeoiei iaoiaeii aiieiai/ii? iiaeeeaoei? oa aeiceiao?i? ?aaeiaoeieii?
ae?? ia ethaeeio ? oeeoiaaiaoe/iee, a iniiai yeiai eaaeeoue aeniea
/ooeeainoue niaaeeiaeo no?oeoo? eeioeie aei ii?iiiiaiiy ( Ai/eia I.I.e
ae?.,1992). E?ii oiai, iooaaaiiee aoaeo, caiiaeiyiee ii?iiiiaiiyi a
noaoaaeo oa niiaoe/ieo eeioeiao ethaeeie, iiaea aooe i?e/eiith
aeieeiaiiy ?yaeo oai?ia c aaiaoe/iith eiiiiiaioith. Aeinaiae aaiaoe/ieo
aeineiaeaeaiue, aeeiiaieo a ssiiii? iiney aoiiiiai aiiaa?aeoaaiiy
Oi?iniie oa Iaaanae?, a oaeiae ?acoeueoaoe oeeoiaaiaoe/iiai eiio?ieth ca
eiioeiaaioaie, yei iino?aaeaeaee aianeiaeie aaa?i? ia *AAN,
iiaeoaa?aeothoue iaiaoiaeiinoue iiaeaeueoiai iaeiie/aiiy aeaieo i?i
/anoioo oa oeie ii?ooaiue o?iiiniiiiai aia?aoo niiaoe/ieo eeioei o
ae?oae, ye? iaoeathoue a ?aa?iiao c iani?eyoeeaeie ?aae?iaeieia?/ieie
oiiaaie (Naaaiueeaaa A.A. e ae?.,1994; I?e?inueea I.A. oa ?i.,1995;
Bender M.A., Awa A.A. et al.,1988).

Naia oeeoiaaiaoe/ia ianoaaeaiiy ae?oae, ye? a neeo iniaeeainoae
iiaaae?iee, oiia aeeooy, ?iaeea?aeoaeueiiai iaoaaie?cio ? iaea?eueo
a?aceeaei eiioeiaaioii oa iaeaooi?i aaiioiiaeo Oe?a?ie ? oiio
aaaaeathoueny iaea?eueo e?eoe/ieie a?oiaie iino?aaeaeaeeo, ia?
i??i?eoaoia cia/aiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiii, oaiaie

?iaioa aeeiiaia a ?aieao Aea?aeaaii? iaoeiai-oaoi?/ii? i?ia?aie “Caoeno
aaiioiiaeo ianaeaiiy Oe?a?ie”(a?aio 01.01.01/ 011) a eaai?aoi???
oeeoiaaiaoeee ?inoeoooo aenia?eiaioaeueii? ?aae?ieia?? Iaoeiaiai oeaio?o
?aae?aoe?eii? iaaeeoeeie AII Oe?a?ie.

Iaoa ? caaea/? aeine?aeaeaiue

Iaoith aeaii? ?iaioe ? ioe?iea noaio o?iiiniiiiai aia?aoo e?ioioeeo?a
ia?eoa?e/ii? e?ia? ae?oae Oe?a?ie, ye? iaoeathoue a ?aeiiao aeiaae?iiy
?aae?iaeoeaieo iiaae?a a ?acoeueoao? aaa??? ia *i?iiaeeuenuee?e AAN

Aeey aeinyaiaiiy iinoaaeaiii? iaoe iio??aii aoei ae??oeoe ne?aeoth/?
caaea/?:

1. Aeyaeoe /anoioo oa oeie o?iiiniiieo aaa?aoe?e a e?ioioeeoao
ia?eoa?e/ii? e?ia? a?oi ae?oae, ye? iaoeathoue ia oa?eoi??yo Oe?a?ie c
iecueeith u?euei?noth caa?oaeiaiiy a?oioo ?cioiiaie oeac?th .

2. Aeyaeoe /anoioo oa oeie o?iiiniiieo aaa?aoe?e a e?ioioeeoao
ia?eoa?e/ii? e?ia? ae?oae, ye? iaoeathoue ia oa?eoi??yo c aenieith
u?euei?noth caa?oaeiaiiy a?oioo ?cioiiaie oeac?th.

3. I?iaanoe ii??aiyeueio ioe?ieo oeeoiaaiaoe/iiai noaio niiaoe/ieo
ee?oei ae?oae, ye? iaoeathoue ia oa?eoi??yo c iecueeei oa i?aeaeuaiei
oiiii ?ii?coth/iai ii?ii?iaiiy.

4. Aea/eoe aeeiai?eo o?iiiniiiiai iooaaaiaco a e?ioioeeoao ia?eoa?e/ii?
e?ia? ae?oae, ye? iaoeathoue ia iaea?eueo caa?oaeiaieo ( a
?aae?iaeieia?/iiio a?aeiioaii?) oa?eoi??yo Oe?a?ie.

Iaoeiaa iiaecia ?iaioe

Aia?oa a Oe?a?i? aea/ai? iniaeeaino? ?aae?i?iaeoeiaaiiai
oeeoiaaiaoe/iiai aoaeoo a e?ioioeeoao ia?eoa?e/ii? e?ia? ae?oae c
/ioe?ueio ianaeaieo ioieo?a Ia?ooeueeiai ?aeiio, ye? ?icoaoiaai? o
iai?yieo cao?aeiiai *i?iiaeeuenueeiai ?aae?iaeoeaiiai ne?aeo, iathoue
iaeiaeia? eaiaeoaooii-aaio?i?/i? oiiae ? a?ae??ciythoueny o?eueee ca
nooiaiai ?aae?aoe?eiiai caa?oaeiaiiy aeiae?eey. Aeyaeaii iiceoeaio
ei?aeyoe?th i?ae /anoioith niaoeeo?/ieo oeeoiaaiaoe/ieo ia?ea??a
ii?ii?iiy oa u?euei?noth caa?oaeiaiiy a?oioo ?aae?iioee?aeaie. I?e
iiaoi?iiio ianoaaeaii? oeo naieo in?a anoaiiaeaii iaeiie/aiiy
noaa?eueieo oa ianoaa?eueieo aaa?aoe?e o?iiiniiiiai oeio c /anii.
I?aeoaa?aeaia aeioe?euei?noue i?iaaaeaiiy oeeoiaaiaoe/ieo ianoaaeaiue
e?eoe/ieo eiioeiaaio?a aeey a?ieia?/ii? ?iaeeeaoe?? iooaaaiii? ae??
?ii?coth/iai ii?ii?iaiiy.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a: io?eiai? aeai? iiaeooue
aooe aeei?enoai? aeey anoaiiaeaiiy i?neyaaa??eiiai niiioaiiiai ??aiy
o?iiiniiieo iooaoe?e o aeeoy/eo eiioeiaaio?a, ye? iino?eii iaoeathoue ia
caa?oaeiaieo ?aae?iioee?aeaie oa?eoi??yo; aeae?eaiiy a?oi ?eceeo ca
oeeoiaaiaoe/ieie e?eoa??yie; ?ic?iaea i?aeoiae?a aei a?ieia?/ii?
aeiceiao??? ?aae?aoe?eiiai iaaaioaaeaiiy ia ethaeeio i?e o?ii?/iiio
ii?ii?iaii? iaei? ?ioaineaiino?..

Iniaenoee aianie caeiaoaa/a.

Aaoi?ii iniaenoi i?iaaaeaii iinoaiiaeo eoeueoo?e e?ioioeeo?a
ia?eoa?e/ii? e?ia? oa i?eaiooaaiiy i?aia?ao?a iaoaoacieo o?iiinii ;
cae?eniaii oeeoiaaiaoe/iee aiae?c i?aia?ao?a c a?coaeueiei a?oiiaei
ea??ioeioaaiiyi. Aeine?aeaeaii /anoioo oa niaeo? aaa?aoe?e o?iiinii a
e?ioioeeoao ia?eoa?e/ii? e?ia? ae?oae ? ca’ycie i?ae ae?aaeaii?noth
oeeoiaaiaoe/iiai aoaeoo oa ?ioaineai?noth ?aae?iaeoeaiiai caa?oaeiaiiy
oa?eoi??e, ia yeeo aiie i?iaeeaathoue. Aeeiiaii noaoenoe/io ia?iaeo
io?eiaieo ?acoeueoao?a.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??.

Iaoa??aee aeena?oaoe?eii? ?iaioe aeiiia?aeaeeny ia ?anioae?eainuee?e
iaoeia?e eiioa?aioe?? “Aeooaeuei? ieoaiiy aeiaaiaoeee oa ?ioiieia??” (i.
Iieoaaa, 1994); II c’?cae? Iaaee/ieo aaiaoee?a Oe?a?ie (i. Euea?a, 1995)
oa aoee aeeth/ai? a aeieeaaee, i?aaenoaaeai? ia Ui??/i?e eiioa?aioe??
Health Physics Society USA (i. Nai-O?aioeenei, NOA, 1994), Ia?oiio
c’?cae? iaaee/ieo aaiaoee?a ?in?? (i. Iineaa, 1995), Oe?a?inueeiio
Eiia?an? ?aae?ia?ieia?a (i. Ee?a, 1995), Ae?oa?e I?aeia?iaei?e
eiioa?aioe?? “Iooaaaie aeiae?eey a iiioeyoe?yo ethaeeie” (i. I?aaa,
1995), Iaoeiai-i?aeoe/iiio nai?ia?? “Iaaee/i? iane?aeee *i?iiaeeuenueei?
eaoano?ioe” (i. Ee?a, 1996).

Ioae?eaoe??

Ca oaiith aeena?oaoe?? iioae?eiaaii 8 ?ia?o: 4 ?iaioe a iaoeiaeo
aeo?iaeao oa 4 ioae?eaoe?? a iaoa??aeao oa oacao eiioa?aioe?e,
n?iiic?oi?a, c’?cae?a.

No?oeoo?a oa ia’?i aeena?oaoe??

Aeena?oaoeiy neeaaea?oueny c anooio, iaeyaeo eioa?aoo?e, ?icae?eo
aeanieo aeineiaeaeaiiue, ?o iaaiai?aiiy, aeniiaeia, aeaciaieea
oeeoiaaii? eioa?aoo?e. ?iaioa aeeeaaeaia ia 107 noi??ieao iaoeiiieno,
?ethno?iaaia 23 oaaeeoeyie oa 4 ?enoieaie. A?ae?ia?ao?/iee aeac?aiee
iae?/o? 130 aeaea?ae.

INIIAIEE CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiue

Iaoa??aeii aeine?aeaeaiue aoee e?ioioeeoe ia?eoa?e/ii? e?ia? aeeoy/eo
eiioeiaaio?a ianaeaiiy, ye? caciaee aieeao iino?eii? ae?? ?aae?aoe??
iaei? ?ioaineaiino? a ?acoeueoaoi caa?oaeiaiiy oa?eoi?ie
?aaeiiioeeiaeaie aiane?aeie aaa?i? ia *AAN. Ianoaaeai? a?oie iaoeaee a
n. Iaea *a?i?a?aea, n. Aaeeea *a?i?a?aea, n. Ia?oio?aaiaaa, n.
Aenooiiae/? Ia?ooeueeiai ?aeiio AEeoiie?nueei? iaeano?, ye?
oa?aeoa?ecoaaeenue ?aeaioe/ieie eaiaeoaooii-aaio?i?/ieie, ee?iaoe/ieie
oa nioe?aeueieie oiiaaie ? a?ae??ciyeenue o?eueee ca u?euei?noth
caa?oaeiaiiy a?oioo ?cioiiaie oeac?th, yea a na?aaeiueio neeaaeaea 3,93;
4,37; 6,13 oa 14,5 E?/ei2 a?aeiia?aeii (oaae. 1).

Eiio?ieai aeey ii??aiyiiy io?eiaieo aeaieo aoee ?acoeueoaoe
oeeoiaaiaoe/iiai ianoaaeaiiy oeiey??a i. Ee?aa, aea u?euei?noue
caa?oaeiaiiy a?oioo ?cioiiaie oeac?th noaiiaeea a na?aaeiueiio 0,7
E?/ei2 oa n. ssaioei ssaioeinueeiai ?aeiio Ee?anueei? iaeano?, yeee ca
aeaieie IIC Oe?a?ie ? oiiaii-/enoei ca?aeii ?aae?aoe?eiiai oiio (0,3
E?/ei2).

Oaaeeoey 1

Noia?iee ia’?i i?iaaaeaieo oeeoiaaiaoe/ieo aeine?aeaeaiue

Ianaeaiee ioieoNa?aaeiy u?euei?noue caa?oaeiaiiy a?oioo Cs137,

E?/ei2E?euee?noue ianoaaeaieo in?aE?euee?noue i?iaiae?ciaaieo iaoaoac n.
ssaioei0,3208000,00i. Ee?a0,7306000,00n. I.*a?i?a?aea3,93244800,00n.
A.*a?i?a?aea4,37244800,00n. Ia?oio?aaiaaa6,13255000,00n. Aenooiiae/?,
199014,50255000,00n. Aenooiiae/?, 199114,50244800,00Anueiai:17234400,00

Aeey oeeoiaaiaoe/iiai ianoaaeaiiy a?aeae?aee ae?oae a?eii a?ae 8 aei 15
?ie?a, ye? a?ae /ano ia?iaeaeaiiy iaoeaee a aeai?e i?noeaaino? oa
caia?a/oaaee na?aeiiee eiioaeo ?c aoaeue-yeeie iooaaaiieie oaeoi?aie.

Iaoa??aeii oeeoiaaiaoe/iiai aeine?aeaeaiiy aoee e?ioioeeoe ia?eoa?e/ii?
e?ia?, ye? io?eioaaee c aaiicii? e?ia? e?eoueiai? aaie oa eoeueoeaoaaee
ca caaaeueiii?eeiyoith iaoiaeeeith a aeeaeeueiiio na?aaeiaeu? RPMI 1640,
c OAA Difco M, aac aeiaeaaaiiy aia??iiaeueii? oaey/i? ne?iaaoee oa
aioea?ioee?a, i?ioyaii 48 aiaeei, ui aeaaaei ciiao aiae?coaaoe ee?oeie
ia?aaaaeii ia?oiai i?oico.

Aiae eiaeiiai ianoaaeaiiai aiaeicoaaee ia iaioa 200 iaoaoac.
Eeaneoieaoeiy oa iaoiae a?aooaaiiy o?iiiniiieo aaa?aoeie aiaeiiaiaeaee
caaaeueiii?eeiyoei (Ai/eia I.I., 1974). A?aoiaoaaee ani aaa?aoei?
o?iiaoeaeiiai (iaeeii/i? o?aaiaioe, o?iiaoeaei? iai?ie) oa o?iiiniiiiai
(aoeaio?eee, aeeoeaio?eee, oeaio?e/i? e?eueoey, aiiiaeuei?
iiiioeaio?eee) oeiia. Anueiai a oiaei aeeiiaiiy ?iaioe ianoaaeeee 172
iniae oa i?iaiaeicoaaee 34400 iaoaoac.

Noaoenoe/io ia?iaeo ?acoeueoao?a aeine?aeaeaiue cae?enithaaee
canoiniaoth/e caaaeueiii?eeiyo? iaoiaee iaoaiaoe/ii? noaoenoeee c
aeei?enoaiiyi ia?niiaeueiiai eiii’thoa?a IBM 486-DX2/66 oa iaeao?a
i?ia?ai: Statgraphics aan?? 3.0 o??ie Statistical Graphics Corporations
(NOA); Exel aa?n?? 97 for Windows 95 o??ie Microsoft.

?acoeueoaoe aeanieo aeine?aeaeaiue oa ?o iaaiai?aiiy

Ine?eueee iaie aoee ianoaaeai? ??ci? aeeoy/? eiioeiaaioe ianaeaiiy
Oe?a?ie (oeiey?? i.Ee?aa, n. ssaioei oa n?e Ia?ooeueeiai ?aeiio
AEeoiie?nueei? iaeano?), ye? iaoeathoue ia oa?eoi??yo, ui
a?ae??ciythoueny ca nooiaiai aeieia?/iiai caa?oaeiaiiy aeioe?eueii aoei
i?iaanoe ii??aiyeueio ioe?ieo oeeoiaaiaoe/iiai noaio e?ioioeeo?a
ia?eoa?e/ii? e?ia? aeey aecia/aiiy aianeo ?aae?aoe?eii? eiiiiiaioe a
oi?ioaaiiy niiaoe/ieo oeeoiaaiaoe/ieo aoaeo?a. Noia?i? ?acoeueoaoe
oeeoiaaiaoe/iiai aiae?co iaaaaeai? a oaae. 2.

Oaaeeoey 2.

Iniiai? oeie o?iiiniiieo aaa?aoe?e a ianoaaeaieo a?oiao

Ianaeaiee ioieoCaaaeueia /anoioa aaa?aioieo iaoaoac,%(M + m)Caaaeueia
/anoioa aaa?aoe?e o?iiinii, % (M + m)?iciao ?iaeea?aeoaeueieo eieeaaiue
aaa?aoe?e o?iiinii, %n. ssaioei 1,44+0,231,46+0,240,25-4,5i. Ee?a
3,40+0,243,40+0,241,5-6,5n. I.*a?i?a?aea3,05+0,223,11+0,240,5-5,0n.
A.*a?i?a?aea3,17+0,283,23+0,291,0-7,0n.
Ia?oio?aaiaaa3,34+0,463,34+0,460,0-8,5n. Aenooiiae/?,
19903,90+0,283,90+0,281,5-6,5n. Aenooiiae/?,
19915,48+0,505,48+0,501,0-11,0

Aiae?coth/e io?eiai? ?acoeueoaoe, iaie aoei aeyaeaii ne?aeoth/a. O
ae?oae, ye? iaoeathoue ia oa?eoi??yo c i?aeaeuaiiei oiiii
?ii?coth/iai ii?ii?iaiiy,

Oaaeeoey 3

*anoioa oa oeie o?iiiniiieo aaa?aoe?e a e?ioioeeoao ia?eoa?e/ii? e?ia?
ae?oae, ye? iaoeathoue ia oa?eoi??yo, caa?oaeiaieo ?aae?iioee?aeaie
aiane?aeie aaa??? ia *i?iiaeeuenuee?e AYN, (M + m).

*anoioa aaa?aoe?e ia 100 iaoaoac Ianaeaiee O?iiaoeaeiiai
oeioO?iiiniiiiai
oeioIoieoIaeei.o?Iai?ieNoiaIa?i.o?.Aeeoeaio?eee.Oeaio?e/.

E?eueoey.O?aine.Aoeaio?.

E?eueoey.NoiaI.*a?i?a?aea 1,42 +0,14 0,00+0,00 1,42 +0,14
1,02+0,15 0,15+0,06 0,10 +0,05 0,00+0,00 0,42 +0,09 1,69
+0,2A.*a?i?a?aea 1,56 +0,14 0,00+0,00 1,56 +0,14
1,06+0,17 0,19+0,07 0,10 +0,05 0,00+0,00 0,31 +0,11 1,67
+0,22Ia?oio?aaiaaa 1,50 +0,23 0,00+0,00 1,50 +0,23
1,04+0,17 0,26+0,07 0,22 +0,09 0,08 +0,06 0,24 +0,07
1,84 +0,27Aenooiiae/?, 1990 1,92 +0,19 0,00+0,00 1,92
+0,19 1,22+0,18 0,26

+0,09 0,16

+0,06 0,06+0,04 0,28

+0,09 1,98

+0,24Aenooiiae/?, 1991 3,06

+0,36 0,00+0,00 3,06

+0,36 1,35

+0,19 0,38

+0,09 0,19

+0,05 0,15

+0,05 0,35

+0.09 2,42

+0,29ssaioei 1,04 +0,22 0,04+0,02 1,08+0,22 0,24+0,06 0,06+0,03
0,01 +0,01 0,05 +0,04 0,03 +0,02 0,39 +0,08Ee?a
2,53

+0,21 0,00+0,00 2,53

+0,21 0,63

+0,13 0,02

+0,02 0,03

+0,02 0,00+0,00 0,18

+0,07 0,87

+0,15

na?aaeiueia?oiiaa /anoioa o?iiiniiieo aaa?aoe?e a??ia?aeii (? <0,05) aaea?/? ia?aaeuo? aiaeia?/i? aeai?, io?eiai? a eiio?ieuei?e a?oi? ae?oae c n.ssaioei ? noaiiaeoue 3,11+0,24 % - n. I.*a?i?a?aea ; 3,23+0,29 % - a n.A.*a?i?a?aea ; 3,34+0,46 % - a n.Ia?oio?aaiaaa ; 3,90+0,28 % – a n.Aenooiiae/? i?e 1,46+0,24% a eiio?ie? (oaae.2). A oie aea /an aoei cao?eniaaii aeinoaoiuei aenieee ??aaiue ?ioaa?aeueieo oeeoiaaiaoe/ieo iieaciee?a ia oa?eoi??? c iecueeei ??aiai ?aae?aoe?eiiai caa?oaeiaiiy – o oeiey??a i. Ee?aa(3,4 + 0,24 %), ui iiaea aooe iia’ycaia c iino?eiei i?an?iaii ?ioeo iooaaaiieo caa?oaeithaa/?a aeiae?eey (O?ieia A.I., 1994). Aiae?coth/e ye?niee neeaae oeeoiaaiaoe/ieo iieaciee?a, aoei aeyaeaii, ui ca?eueoaiiy caaaeueii? /anoioe o?iiiniiieo aaa?aoe?e o ae?oae i.Ee?aa noi?iiaaii o?eueee ca ?aooiie aaa?aoe?e o?iiaoeaeiiai oeio, ui na?ae/eoue i?i aieea niaoeeo?/ieo /eiiee?a ia?aae?aoe?eii? i?e?iaee, oa?aeoa?ieo aeey i?iieneiai-i?nueei? aaeiia?aoe??. sse a?aeiii, aaa?aoe?? o?iiaoeaeiiai oeio, iiaeooue ooai?thaaoenue i?e ae?? ??cieo oaeoi??a (o?i?/i? oa a?ieia?/i? iooaaaie, ?iei?ii?iaai? ?aae?iioee?aee), aea ?o aeeaae a caaaeueio /anoioo aaa?aoe?e noaiiaeoue 50 - 70% ( Ai/eia I.I., *aaioa?aa A.I. ,1989). Oea iieiaeaiiy i?aeoaa?aeaeo?oueny o?eueee aeey oa?eoi??e c iecueeei ??aiai caa?oaeiaiiy ?cioiiaie oeac?th (aei 1 E?/ei2 ) – a i.Ee?a?, a oaeiae a eiio?ieueiiio n.ssaioei, aea /anoioa o?iiaoeaeieo aaa?aoe?e neeaaea? 74% (?en.1). picscalex100010009000003f31500000b00050200000000050000000902000000000500 00000102ffffff000400000004010d000400000002010200050000000c02230168020300 00001e00040000002701ffff05020000f700000300010000000080000000008000008080 0000000080008000800000808000c0c0c000c0dcc000a6caf00004040404080808040c0c 0c0411111104161616041c1c1c042222220429292904555555044d4d4d04424242043939 3904ff7c8004ff505004d6009304ccecff04efd6c604e7e7d604ada99004330000046600 000499000004cc00000400330004333300046633000499330004cc330004ff3300040066 0004336600046666000499660004cc660004ff6600040099000433990004669900049999 0004cc990004ff99000400cc000433cc000466cc000499cc0004cccc0004ffcc000466ff 000499ff0004ccff000400003304330033046600330499003304cc003304ff0033040033 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Ee?a; 3 - n. Iaea *a?i?a?aea; 5 - n.Ia?oio?aaiaaa;2 - n. ssaioei; 4 - n. Aaeeea *a?i?a?aea; 6 - n. Aenooiiae/? Oaeei /eiii, ia?aaaaeaiiy aaa?aoe?e o?iiaoeaeiiai oeio a aeuacacia/aiieo aeaio a?oiao, a oaeiae iecueea /anoioa ia?ea??a ae?? ?aae?aoe?? na?ae/eoue, ui aeinoaoiuei aei?noeee eiio?ieue ca i?iaeoeoaie oa?/oaaiiy a 1991 ?ioe? a i Ee?a? oa iiaiioe?iia a?eeiaa oa?/oaaiiy a n. ssaioei i?e iecueeeo ??aiyo caa?oaeiaiiy ?aae?iioee?aeaie cia/ii no?eioaaee ?icaeoie ?aae?i?iaeoeiaaieo aaiaoe/ieo iioeiaeaeaiue. Ne?ae a?aecia/eoe, ui ca?eueoaiiy caaaeueiiai ??aiy o?iiiniiieo aaa?aoe?e a e?ioioeeoao ia?eoa?e/ii? e?ia? ae?oae i.Ee?aa ci?aiaaea? c oaiaeaioe??th, anoaiiaeaiith Ai/eiaei I.I. (1991), aei i?aeaeuaiiy niiioaiiiai ??aiy o?iiiniiieo aaa?aoe?e ca inoaii? 10 ?ie?a. 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00002701ffff050000000c02df001302030000001e00050000000102ffffff0005000000 090200000000040000002701ffff050000000b0200000000030000001e00050000000102 ffffff0005000000090200000000040000002701ffff030000000000 ?en. 3 *anoioa ianoaa?eueieo ia?ea??a ?aae?aoe?eiiai aieeao (aeeoeaio?eee oa oeaio?e/i? e?eueoey) a ianoaaeaieo a?oiao ae?oae. 1. - n. ssaioei ; 4. - n. Aaeeea *a?i?a?aea; 2. - i. Ee?a ; 5. - n. Ia?oio?aaiaaa; 3. - n. Iaea *a?i?a?aea; 6. - n. Aenooiiae/? 1990; 7. - n. Aenooiiae/? 1991. Oae, yeui noia?ia /anoioa oeeo ?aae?aoe?eieo ia?ea??a o ae?oae, ye? iaoeathoue ia oa?eoi??? c iecueeith u?euei?noth caa?oaeiaiiy ?cioiiaie oeac?th a i.Ee?a? oa n.ssaioei noaiiaeea 0,05 oa 0,07 ia 100 iaoaoac a?aeiia?aeii, oi o ae?oae ?c ?aeii?a c aenieith u?euei?noth caa?oaeiaiiy a?oioo ?aae?iioee?aeaie oeae iieaciee neeaaeaa a: n.I.*a?i?a?aea (3,93 E?/ei2) – 0,25, n.A.*a?i?a?aea (4,37 E?/ei2) – 0,29; n.Ia?oio?aaiaaa (6,13 E?/ei2)– 0,48 ia 100 iaoaoac, a n.Aenooiiae/? (14,5 E?/ei2) a 1990 ?. - 0,42; a 1991 ?. – 0,57 ia 100 iaoaoac (?en.3). Caa?oa? ia naaa oaaao oie oaeo, ui u?euei?noue caa?oaeiaiiy a?oioo ?cioiiaie oeac?th a n.Aenooiiae/? aaeai? a?eueoa i?ae a n. Ia?oio?aaiaaa, i?e iaeaea iaeiaeiaiio ??ai? niaoeeo?/ieo iieaciee?a ae?? ?aae?aoe?? (oaae.3). Ie aaaaea?ii, ui a aeaiiio aeiaaeeo oea iiaea aooe iia’ycaia c iooaaaiiith ae??th a?eueo aeoeaiiai ?aae?iioee?aea – no?iioe?th-90, u?euei?noue caa?oaeiaiiy yeiai a n. Ia?oio?aaiaaa a 6 ?ac?a aeua, i?ae a n. Aenooiiae/? ca aeaieie Aea?aeeiia?ae?iiaoo, 1989 ?ieo. Aiae?c i?aaenoaaeaieo ?acoeueoao?a aeaco? ia aeia?o ei?aeyoe?th (r =0,86) i?ae u?euei?noth caa?oaeiaiiy oa?eoi??? ?cioiiaie oeac?th oa /anoioith cono??/a?iino? ianoaa?eueieo iai?i?a o?iiiniiiiai oeio a a?oiao ae?oae, ye? iaoeathoue a ?aeiiao c aenieei ??aiai caa?oaeiaiiy ?aae?iioee?aeaie. sse aeaeii c oaae. 3 oa ?en. 2., uiaei ?ioeo iieaciee?a, oi icia/ai? a?oie ae?oae Ia?ooeueeiai ?aeiio (ia a?aei?io a?ae ?iaeea?aeoaeueieo aeaieo) ia iaee iniaeeaeo a?aei?iiinoae ca caaaeueiith /anoioith o?iiiniiieo aaa?aoe?e, /anoioith aaa?aoe?e o?iiaoeaeiiai oeio, /anoioith aoeaio?ee?a (ia?ieo o?aaiaio?a oa aoeaio?e/ieo e?eaoeue) oa aiiiaeueieo iiiioeaio?ee?a, ui iiaeeeai ? ? iciaeith iaeii??aeiino? aeaii? iiioeyoe??. Oae, /anoioa noaa?eueieo aaa?aoe?e (aiiiaeueieo iiiioeaio?ee?a, aeyaeaieo i?e a?coaeueiiio a?oiiaiio ea??ioeioaaii? ia ?ooeiii iioa?aiaaieo i?aia?aoao) o ae?oae, ye? iaoeathoue ia caa?oaeiaieo ?aae?iioee?aeaie oa?eoi??yo, noaiiaeea a n.Ia?oio?aaiaaa –0,08 ia 100 iaoaoac; a n.Aenooiiae/? a 1990 ?ioe? – 0,06, i?e iiaoi?iiio ianoaaeaii? a 1991 ?ioe? – 0,15 ia 100 iaoaoac; a n. ssaioei a 1995 ?ioe? – 0,05 ia 100 iaoaoac. Oe? iieacieee, oi/a ? a?aeiia?aeathoue niiioaiiiio ??aith - 0,05-0,4 ia 100 ee?oei ca aeaieie Bender M.A. ?c ci?aaaoi?aie (1988), aea ? iaaaoeaiith i?iaiinoe/iith iciaeith aeiaeaoeiaeo niiaoe/ieo caoai?thaaiue. Ne?ae i?aee?aneeoe, ui a on?o ianoaaeaieo a?oiao niinoa??aaeeny cia/i? iaae? ?iaeea?aeoaeueieo eieeaaiue /anoio ye ?ioaa?aeueieo oeeoiaaiaoe/ieo iieaciee?a, oae ? ?aae?i?iaeoeiaaieo aaa?aoe?e (oaae. 2). Oae, ianoaa?euei? ?aae?aoe?ei? ia?ea?e aoee aeyaeai? a n. I.*a?i?a?aea – o 37,5 % ianoaaeaieo ae?oae, A.*a?i?a?aea – o 40 %, Ia?oio?aaiaaa – o 56 %, Aenooiiae/? – o 52 % a 1990 ?. oa 79 % a 1991 ?. i?ioe 10 % a i. Ee?a? oa 20 % a n. ssaioei; noaa?euei? (aiiiaeuei? iiiioeaio?eee) aeyaeaii a n. Ia?oio?aaiaaa – o 8% ianoaaeaieo ae?oae; n. Aenooiiae/? - o 12 % a 1990 ?. oa 24% - a 1991?.oa o 10 % oeiey??a - a n.ssaioei, ui na?ae/eoue i?i i?ae?iaeea?aeoaeueio /ooeea?noue aei ae?? ?aae?aoe?eiiai oaeoi?a. Aeey aeyaeaiiy aeeiai?ee iooaaaiii? ae?? ?aae?aoe?? iaie aoei i?iaaaeaii iiaoi?ia oeeoiaaiaoe/ia ianoaaeaiiy a?oie ae?oae n. 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b3e9040000002d010200040000002d010800040000002d010400040000002701ffff0300 00001e00040000002d010200040000002d010900050000000102ffffff00050000000902 00000000070000001604e1006f0204000400040000002d010800040000002d0104000400 00002701ffff030000001e00040000002d010200040000002d010900050000000102ffff ff0005000000090200000000070000001604e500730200000000040000002d0108000400 00002d010400040000002701ffff030000001e00040000002d010200040000002d010900 050000000102ffffff0005000000090200000000070000001604e5007302000000000400 00002d01080004000000f0010900040000002701ffff050000000c02e500730203000000 1e00050000000102ffffff0005000000090200000000040000002701ffff050000000b02 00000000030000001e00050000000102ffffff0005000000090200000000040000002701 ffff030000000000 ?en. 4 Ii??aiyiiy ?acoeueoao?a oeeoiaaiaoe/iiai ianoaaeaiiy ae?oae, ye? iaoeathoue a n. Aenooiiae/? Ia?ooeueeiai ?aeiio AEeoiie?nueei? iaeano?, i?iaaaeaiiai a 1990 oa 1991 ?.?. 1. Caaaeueia /anoioa o?iiiniiieo aaa?aoe?e; 2. *anoioa aaa?aoe?e o?iiaoeaeiiai oeio; 3. *anoioa aaa?aoe?e o?iiiniiiiai oeio; 4. *anoioa ia?ieo o?aaiaio?a; 5. *anoioa aeeoeaio?ee?a oa oeaio?e/ieo e?eaoeue; 6. *anoioa aoeaio?e/ieo e?eaoeue; 7. *anoioa aiiiaeueieo iiiioeaio?ee?a. A ?acoeueoao? iiaoi?iiai oeeoiaaiaoe/iiai ianoaaeaiiy oe??? a?oie aoei iieacaii, ui na?aaeiueia?oiiaa /anoioa aaa?aoe?e o?iiinii c?inea aei 5,48 + 0,5 ia 100 ee?oei; a??ia?aeii ia?aaeuoth/e ??aaiue 1990 ?ieo - 3,9+0,46 ia 100 iaoaoac. Aiae?c ?? neeaaeiaeo iieacaa oaiaeaioe?th aei ca?eueoaiiy /anoioe aaa?aoe?e ye o?iiiniiiiai, oae ? o?iiaoeaeiiai oei?a. O 58 % ianoaaeaieo ae?oae aoei aeyaeaii a?ae 5 aei 10 aaa?aioieo ee?oei ia iniao (?en.4). Ine?eueee a 1990 oa 1991 ?ioe? a n.Aenooiiae/? iaie a iniiaiiio aoee ianoaaeai? o? ae nai? ae?oe (19 c 24 ae?oae ), i?e ?iaeea?aeoaeueiiio ii??aiyii? ?acoeueoao?a oeeoiaaiaoe/iiai aiae?co oeeo ae?oae aoei cao?eniaaii ??no /anoioe aaa?aoe?e o?iiiniiiiai oeio o 63 % ianoaaeaieo, a oie /an ye cieaeaiiy ??aiy aaa?aoe?e aeaiiai oeio o?eueee o 5 in?a c aeaii? a?oie (aeecueei 26%), ui na?ae/eoue i?i i?iaeiaaeaiiy iooaoe?eiiai i?ioeano a aeai?e a?oi? ? ? iaeiei c e?eoa???a aeey a?aeianaiiy oeueiai ianaeaiiai ioieoo aei oa?eoi??? aacoiiaiiai (iaia’yceiaiai) a?aenaeaiiy. Ni?aa?aeiioaiiy i?ae aeeoeaio?e/ieie oa e?eueoeaaeie o?iiiniiaie noaiiaeei a eiio?ieuei?e a?oi? 6:1, a aeniiiiaaieo a?oiao - aeecueei 1,5:1, ui na?ae/eoue i?i a?eueo ?ioaineaio ae?i?iaoe?th aeeoeaio?e/ieo o?iiinii c /anii i?e iino?ei?e ae?? ?aae?aoe?? iaei? ?ioaineaiino?. sse aoei a?aei?/aii, niaoeeo?/i? oeeoiaaiaoe/i? ia?ea?e iiaeooue aooe aeei?enoai? aeey ioe?iee aeice ii?ii?iaiiy ethaeeie. I?e ae?? ?aae?aoe?? iaei? ?ioaineaiino? ia?aaeueii i?iaanoe oeeoiaaiaoe/io aeiceiao??th aeey ie?aieo in?a, aea iiaeeeai ioe?ieoe aeico ?aae?aoe?? aeey a?oie in?a c ?aeaioe/iei ?aae?aoe?eiei iaaaioaaeaiiyi (Ai/eia I.I. e ae?., 1991). Iaie aoea i?eeiyoa ni?iaa ?aeiino?oeoe?? a?oiiai? aeice ca oeeoiaaiaoe/iei aoaeoii ca?aeii caaaeueiii?eeiyoi? oi?ioee Y = +D +D2 , aea Y -/anoioa aeeoeaio?ee?a ia 100 iaoaoac a aeniiiiaai?e a?oi?; D - aeica ?aae?aoe?? a A?, - /anoioa aeeoeaio?ee?a ia 100 iaoaoac a eiio?ieuei?e a?oi?; - eiao?oe??io aeey Ns 137 = 3,4; -eiao?oe??io aeey Ns 137= 6,0. Aeai? eiao?oe??ioe aoee cai?iiiiiaai? G.Littlefield (1980), ye io?eiai? a ?? eaai?aoi??? ia i?aenoaa? aenia?eiaio?a in vitro aeey oeac??aiai aeaea?aea (Ns 137) c a?aeiinii iecueeith iiooaei?noth aeice (oaae.4). I?e ?ic?aooieo aeice ?aii?oaaee eaaae?aoe/io /anoeio ??aiyiiy, ia a?aoiaoaaee o?eaae?noue aeeooy e?ioioeeo?a a ia?eoa?e/i?e e?ia? oa i?eioneaee, ui o?ii?/ia ae?y ?aae?aoe?? iaei? ?ioaineaiino? i?eaiaeeoue aei iino?eiiai ooai?aiiy aeeoeaio?e/ieo o?iiinii, 50% yeeo ui??/ii ae?i?io?oueny. Oaaeeoey 4. Cia/aiey aoaeoeaii? aea?aaeaioii? aeice (AAAe) o ae?oae, ye? iaoeathoue a Ia?ooeueeiio ?aeii? AEeoiie?nueei? iaeano? ia iniia? oeeoiaaiaoe/ieo e?eoa???a. Ianaeaiee ioieoAeaoaianoa-aeaiiyE?e-ouei?nyoe?ai?neyaaa???E?e-oueaeeoeai-o?ee?a a a?oi?(%)A?aenioie aeeoeaio?ee?a aeyaeaieo a a?oi?E?e-oue ooai?aieo aeeoeaio?ee?a ia iiiaio ianoaaeaiiy.Aeicaii?ii?-iaiiy(nCa)I.*a?i?a?aeaAa?anaiue1989420.1547.000. 318.50A.*a?i?a?aeaAEiaoaiue1989430.1947.000.3910.00Ia?oio?aaiaaaEa?oaiue 1990480.2639.000.6618.80Aenooiiae/?O?aaaiue1990490.2639.000.6618.80 sse aeaeii c i?eaaaeaiieo aeaieo, aaee/eia aeoioeueiaaii? iiaeeiooi? AAAe aeinoaoiuei aeniea a on?o ianoaaeaieo a?oiao ae?oae c Ia?ooeueeiai ?aeiio. Oae, yeui u?euei?noue caa?oaeiaiiy a?oioo ?cioiiaie oeac?th a i?noeyo i?iaeeaaiiy aeaieo a?oi ae?oae a?ae??ciy?oueny iaeaea a 4 ?ace, oi aaee/eia AAAe - o?eueee aaea?/?, ua ?ac i?aeoaa?aeaeoth/e i?eiouaiiy, ui iaa?oue aeineoue iae? aeice ?ii?coth/iai ii?ii?iaiiy caeaoi? aecaaoe nooo?a? iioeiaeaeaiiy a aaiaoe/iiio aia?ao? niiaoe/ieo ee?oei, a aeaiiio aeiaaeeo - e?ioioeeo?a ia?eoa?e/ii? e?ia?. AENIIAEE. Iae? aeice ?ii?coth/iai ii?ii?iaiiy i?e o?ii?/i?e ae?? i?eaiaeyoue aei a??ia?aeiiai i?aeaeuaiiy /anoioe aaa?aoe?e o?iiiniiiiai oeio a e?ioioeeoao ia?eoa?e/ii? e?ia? ae?oae, ye? iaoeathoue a ?aeiiao aeiaae?iiy ?aae?iioee?ae?a. *anoioa niaoeeo?/ieo ia?ea??a ?aae?aoe?eii? ae?? iiceoeaii ei?aeth? ?c u?euei?noth caa?oaeiaiiy a?oioo ?cioiiaie oeac?th. I?e iiaoi?iiio oeeoiaaiaoe/iiio ianoaaeaii? oeo naieo ae?oae, ye? iaoeathoue ia iaea?eueo caa?oaeiai?e (a ?aae?iaeieia?/iiio a?aeiioaii?) oa?eoi???, ca?a?no?iaaii no?eea i?aeaeuaiiy ??aiy o?iiiniiieo aaa?aoe?e c /anii, ui aeaco? ia i?iaeiaaeaiiy aieeao ae?? ?aae?aoe??. I?aeaeuaiiy /anoioe noaa?eueieo aaa?aoe?e iai?iiiai oeio (neiao?e/ieo o?aineieaoe?e) c /anii cao?eniaaii o?eueee o ae?oae, ye? iaoeathoue ia oa?eoi??? c u?euei?noth caa?oaeiaiiy a?oioo ?cioiiaie oeac?th 5-15 E?/ei2. ?acoeueoaoe oeeoiaaiaoe/iiai ianoaaeaiiy ?ai?acaioaeaieo a?oi ianaeaiiy, ye? iaoeathoue a ?aeiiao c iani?eyoeeaei aeieia?/iei noaiii, iiaeooue aooe aeei?enoai? aeey iiioeyoe?eii? ?iaeeeaoe?? iooaaaiii? ae?? caa?oaeithaa/?a iaaeieeoiueiai na?aaeiaeua ye ?aae?aoe?eii?, oae ? ia?aae?aoe?eii? i?e?iaee; aeey ea?oia?aooaaiiy oa?eoi??? Oe?a?ie ca iooaaaiiei oiiii; aecia/aiiy a?oi i?aeaeuaiiiai ?eceeo ca oeeoiaaiaoe/ieie e?eoa??yie. IA?AE?E IIOAE?EIAAIEO I?AOeUe CA OAIITH AeENA?OAOe?? 1. Pilinskaya M.A., Dibsky S.S., Dibskaya E.B. The cytogenetic effect in lymphocytes from the peripheral blood of children living in population center contaminated with radionuclides in the Ovruts district of the Zhitomir region of Ukraine. // Cytology and Genetics.- 1992.- V.26.- N4.- P.8-11. 2. Iieiinueea I.A., Aeeanueeee N.N., Aeeanueea I.A. Oeeoiaaiaoe/iee aoaeo a eiioioeeoao ia?eoa??eii? e?iai aeioae, ui iaoeathoue a aeayeeo ianaeaiieo ioieoao Ia?ooeueeiai ?aeiio AEeoiie?nueei? iaeanoi Oe?a?ie, caa?oaeiaieo ?aae?iioee?aeaie// Oeeoieiaiy i aaiaoeea.-1992.-O.26.-N 4.- N.10-14. 3. Ieeeineay I.A., Oaiaooi A.I., Aeuaneee N.N., ?aaeueei Ae.A., Aaith?eoeia A.A., Aeuaneay A.A. Oeeoiaaiaoe/aneee iiieoi?eia eeoe, iino?aaeaaoeo io aaa?ee ia *a?iiaueueneie AYN / // Oeeoieiaey e aaiaoeea,-1994.- O.28.- N 3.- N. 18 - 25. 4. Ieeeineay I.A., Aeuaneee N.N., Ciaaaneay E.A, Aeuaneay A.A Aeeiaieea i?ioaeaiey iooaoeeiiiiai i?ioeanna a eeioioeeoao ia?eoa?e/aneie e?iae /aeiaaea a oneiaeyo iinoiyiiiai aicaeaenoaey iaeuo o?iaiae eiiece?othuae ?aaeeaoeee /Oeeoieiaey e aaiaoeea,-1995.-O.29.-N 3.-N.56-61. 5. Ieeeineay I.A., Oaiaooi A.I., Aeuaneee N.N, Iaaeai E.?., ?aaeueei Ae.A., Aeuaneay A.A., Ciaaaneay E.A. ?ieue ino?iai e iinoiyiiiai iaeo/aiey a noaeueaa aaa??aioiuo eeioioeeoia o eeoe, iino?aaeaaoeo a ?acoeueoaoa aaa?ee ia *AYN // Iaoa?. aeiee. ?aaeeiaeieia. Nueacaea. - O.3. – Ioueii. - 1993. – N.801. 6. Iieiinueea I.A., Aeeanueeee N.N., Aeeanueea I.A., Cia?anueea I.A. oa ii. ?acoeueoaoe oeeoiaaiaoe/iiai iiiioi?iiao a?oi aeioae, yei iaoeathoue a ciiao aei?noeiai ?aaeiaoeieiiai eiio?ieth // Iaoa?iae. aeiiiaiae. ?anioae. iaoe. eiioa?.” Aeooaeueii ieoaiiy aeiaaiaoeee oa iioiieiai?” Iieoaaa, 1994: - Ee?a-Iieoaaa. - 1994. - N. 109-110. 7. Aeeanueeee N.N., Aeeanueea I.A., Cia?anueea ?.A. Aeeiai?ea ia?aa?ao iooaoe?eieo i?ioean?a o ae?oae, ye? iaoeathoue ia ?aae?aoe?eii caa?oaeiaieo oa?eoi??yo Oe?a?ie // Oac. II c’?caeo Iaaee/ieo aaiaoee?a Oe?a?ie (18-20 aeiaoiy 1995?.) - Euea?a. - 1995. - N. 61. 8. Aeeanueea I.A. Aeeiai?ea iooaoe?eiiai i?ioeano a e?ioioeeoao ia?eoa?e/ii? e?ia? ae?oae, ye? iaoeathoue a cii? aei?noeiai ?aae?aoe?eiiai eiio?ieth // Iaoa?. 3-ai neiiic?oio ”Ae?aaiinoeea oa i?io?eaeoeea iaaaoeaieo iane?aee?a ?aae?aoe??” - Ee?a. - 1997. - N. 101. Aeeanueea I.A. Oa?aeoa? oeeoiaaiaoe/ieo iioeiaeaeaiue o ae?oae, ye? iaoeathoue ia oa?eoi??yo, caa?oaeiaieo ?aae?iaeoeaieie iiaaeaie aiane?aeie aaa??? ia *i?iiaeeuenuee?e AAN.- ?oeiien. Aeena?oaoe?y ia caeiaoooy a/aiiai nooiaiy eaiaeeaeaoa a?ieia?/ieo iaoe ca oaoii 03.00.15- Aaiaoeea. Oe?a?inueeee iaoeiaee a?a??i?/iee oeaio?, Ee?a, 1998. Aeena?oaoe?eia ?aaioa i?enay/aia ioe?ioe? oeeoiaaiaoe/ieo iioeiaeaeaiue a e?ioioeeoao ia?eoa?e/ii? e?ia? a?oi ae?oae, ye? iaoeathoue a aeayeeo naeao Oe?a?ie a cao?aeiiio iai?yieo *i?iiaeeueneiai ?aae?iaeoeaiiai “ne?aeo”. Aoei aeyaeaii a??ia?aeia i?aeaeuaiiy caaaeueii? /anoioe aaa?aioieo iaoaoac oa o?iiiniiieo aaa?aoe?e (aeeth/ath/e ianoaa?euei? oa noaa?euei? ia?ea?e ae?? ?aaeeaoe??) o ae?oae ?c n?e : I.*a?i?a?aea, A. *a?i?a?aea, Aenooiiae/?, Ia?oio?aaiaaa Ia?ooeueeiai ?aeiio AEeoiie?nei? iaeano? c u?euei?noth caa?oaeiaiiy a?oioo ?cioiiaie oeac?th a?ae 3,9 aei 14,5 E?/ ei2 i?e ii??aiyii? c eiio?ieueieie a?oiaie. A ii?ii?iaieo a?oiao oeeoiaaiaoe/i? iioeiaeaeaiiy ciaoiaeeeenue a iaaeao a?ae 0,25 aei 0,57 ia 100 iaoaoac aeey aeeoeaio?ee?a ? oeaio?e/ieo e?eaoeue oa a?ae 0 aei 0,15 ia 100 iaoaoac aeey aiiiaeueieo iiiioeaio?ee?a, iiceoeaii ei?aethth/e ?c u?euei?noth caa?oaeiaiiy a?oioo ?aae?iioee?aeaie. I?e iiaoi?iiio ianoaaeaii? oeo naieo ae?oae, ye? iaoeathoue ia iaea?eueo caa?oaeiai?e oa?eoi??? (14,5 E?/ei2 ), aoei anoaiiaeaii ??no oeeoiaaiaoe/ieo aoaeo?a oa iaeiie/aiiy aaa?aoe?e o?iiiniiiiai oeio c /anii. Aoei i?iaaaeaii ?ic?aooiie aoaeoeaii? aea?aaeaioii? aeice ?ii?coth/iai ii?ii?iaiiy ia iiioeyoe?eiiio ??ai? ca oeeoiaaiaoe/ieie e?eoa??yie aeey ianoaaeaieo a?oi ae?oae Ia?ooeueeiai ?aeiio. Eeth/ia? neiaa: ?ii?coth/a ii?ii?iaiiy, e?ioioeeoe ia?eoa?e/ii? e?ia?,o?iiiniii? aaa?aoe??, oeeoiaaiaoe/ia aeiceiao??y. Aeuaneay A.A. Oa?aeoa? oeeoiaaiaoe/aneeo iia?aaeaeaiee o aeaoae, i?iaeeaathueo ia oa??eoi?eyo, caa?yciaiiuo ?aaeeiaeoeaiuie inaaeeaie a ?acoeueoaoa aaa?ee ia *a?iiaueueneie AYN. - ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa aeieiae/aneeo iaoe ii niaoeeaeueiinoe 03.00.15 – Aaiaoeea, Oe?aeineee iao/iue aeaeaie/aneee oeaio?, Eeaa, 1998. Aeenna?oaoeeiiiay ?aaioa iinayuaia ioeaiea oeeoiaaiaoe/aneeo iia?aaeaeaiee a eeioioeeoao ia?eoa?e/aneie e?iae a?oii aeaoae, i?iaeeaathueo a iaeioi?uo naeao Oe?aeiu a caiaaeiii iai?aaeaiee *a?iiaueueneiai ?aaeeiaeoeaiiai “neaaea”. Auei auyaeaii cia/eoaeueiia oaaee/aiea iauae /anoiou aaa??aioiuo iaoaoac e o?iiiniiiuo aaa??aoeee ( aeeth/ay ianoaaeeueiua e noaaeeueiua ia?ea?u ?aaeeaoeeiiiiai aeaenoaey) o aeaoae ec nae : I.*a?ieaiaea, A. *a?ieaiaea, Aunooiiae/e, Ia?oio?aaiaaia Ia?o/neiai ?aeiia AEeoiie?neie iaeanoe n ieioiinoueth caa?yciaiey ii/au ecioiiaie oeacey io 3,9 aei 14,5 Ee/ ei2 ii n?aaiaieth n eiio?ieueiuie a?oiiaie. A yeniiie?iaaiiuo a?oiiao oeeoiaaiaoe/aneea ia?ooaiey eieaaaeenue io 0,25 aei 0,57 ia 100 iaoaoac aeey aeeoeaio?eeia e oeaio?e/aneeo eieaoe e io 0 aei 0,15 ia 100 iaoaoac aeey aiiiaeueiuo iiiioeaio?eeia, iieiaeeoaeueii ei??aee?oy n ieioiinoueth caa?yciaiey ii/au ?aaeeiioeeeaeaie. I?e iiaoi?iii ianeaaeiaaiee oao aea naiuo aeaoae, i?iaeeaathueo ia iaeaieaa caa?yciaiiie oa??eoi?ee (14,5 Ee/ ei2 ), aue ioia/ai ?ino oeeoiaaiaoe/aneeo yooaeoia e iaeiieaiea aaa??aoeee o?iiiniiiiai oeia ni a?aiaiai. I?aaei?eiyoa iiiuoea ?ann/aoa yooaeoeaiie yeaeaaeaioiie aeicu eiiece?othuaai iaeo/aiey ia iiioeyoeeiiiii o?iaia ii oeeoiaaiaoe/aneei e?eoa?eyi aeey a?oii aeaoae Ia?o/neiai ?aeiia. Eeth/aaua neiaa: eiiece?othuaa eceo/aiea, eeioioeeou ia?eoa?e/aneie e?iae, o?iiiniiiua aaa??aoeee, oeeoiaaiaoe/aneay aeiceiao?ey. Dybskaya E.B. The nature of cytogenetic damages in children living at the territories contaminated by radioactive fallouts as the result of Chernobyl power plant accident.- Manuscript. The dissertaton for a candidate's degree in Biology, speciality 03.00.15 - genetics (biological science). - Ukrainian Scientific Hygienic Center of Ministry of Health Care of Ukraine, Kyiv, 1998. The dissertation is devoted to the evaluation of cytogenetic effects in peripheral blood lymphocytes of children groups from several Ukrainian villages situated in western radioactive Chernobyl trace. A significant increase in the mean frequency of aberrant metaphases and chromosome aberrations (including unstable and stable cytogenetic markers of radiation exposure) in children from v.v. M. Chernigovka, B. Chernigovka, Vistupovichi, Pershetravneve of Ovruch district, Zhitomir region (with the density of soil contamination by cesium isotopes from 3.9 to 14.5 Ci per km2) in comparison with the control groups had been established. In the exposed groups the induced cytogenetic effects was in range from 0.25 to 0.57 per 100 cells for dicentrics and rings and from 0 to 0.15 for abnormal monocentrics and correlated positevely with the level of environmental contamination by radionuclides. Repeated study of the same children from the mostly contaminated village Vistupovichi showed the growth of the cytogenetic effect and the accumulation of the chromosome type aberrations in time. The attempt of radiation dose reconstruction for the exposed children groups on the ground of cytogenetic data had been done. Key words: ionizing radiation, peripheral blood lymphocytes, chromosome aberrations, cytogenetic dosimetry.

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