Ефективність комплексного хірургічного лікування хворих виразковою хворобою (Клініко-експериментальне дослідження): Автореф. дис… д-ра мед. наук / О

OA?EIANUeEEE AeA?AEAAIEE IAAeE*IEE OIIAA?NEOAO

Aaaaee/ Ieaenaiae? Ee?eeiae/

OAeE: 616. 33 — 002. 44 — 089 — 085

AOAEOEAIINOUe EIIIEAENIIAI OI?O?AI*IIAI

EIEOAAIIss OAI?EO AE?ACEIAITH OAI?IAITH

(Eeiiiei-aenia?eiaioaeueia aeineiaeaeaiiy)

14. 01. 03 — Oi?o?aiy

Aaoi?aoa?ao

aeena?oaoei? ia caeiaoooy iaoeiaiai nooiaiy

aeieoi?a iaaee/ieo iaoe

Oa?eia — 1999

Aeena?oaoei?th ? ?oeiien.

?iaioa aeeiiaia a E?einueeiio aea?aeaaiiio iaaee/iiio oiiaa?neoaoi

ii. N.I.Aai?ai?anueeiai IIC Oe?a?ie

Iaoeiaee eiinoeueoaio: aeieoi? iaaee/ieo iaoe, i?ioani? Oanaiei Aieoi?
Iaaeiae/, E?einueeee aea?aeaaiee iaaee/iee oiiaa?neoao ii.
N.I.Aai?ai?anueeiai IIC Oe?a?ie, caaiaeoaa/ eaoaae?e caaaeueii? oi?o?ai?
c aeiaeyaeii ca oai?eie oa eo?nii ?aaiiiaoieiai?

Ioioeieii iiiiaioe:aeieoi? iaaee/ieo iaoe, i?ioani? Eoiaeueoeaa
Aieiaeeie? Iaaiiae/, Oa?eianueeee aea?aeaaiee iaaee/iee oiiaa?neoao IIC
Oe?a?ie, caaiaeoaa/ eaoaae?e oi?o?ai?aeieoi? iaaee/ieo iaoe, i?ioani?
Oeuaiei Ieaenaiae? Ieoaeeiae/, Oa?eianueeee iinoeooo caaaeueii? oa
iaaiaeeeaaeii? oi?o?ai? IIC Oe?a?ie, caaiaeoaa/ aiaeaeieaiiy ia/iiee oa
iiaeoeoieiai? caeiceaeieoi? iaaee/ieo iaoe, i?ioani? A?eia Na?aie
A?eai?iae/, Oa?eianeee iinoeooo oaeineiiaeaiiy eiea?ia IIC Oe?a?ie,
i?ioani? eaoaae?e oi?o?ai? c eo?nii i?ieoieiai?

I?iaiaeia onoaiiaa: Aeiiaoeueeee aea?aeaaiee iaaee/iee oiiaa?neoao ii.
I.Ai?ueeiai IIC Oe?a?ie, eaoaae?a caaaeueii? oi?o?ai? ? 1

Caoeno aiaeaoaeaoueny » 10 » /a?aiy 1999 ?ieo ia caniaeaiii
niaoeiaeiciaaii? a/aii? ?aaee Ae 64.600.01 i?e Oa?eianueeiio
aea?aeaaiiio iaaee/iiio oiiaa?neoaoi IIC Oe?a?ie (aae?ana: 310022, i.
Oa?eia, i?iniaeo Eaiiia, 4).

C aeena?oaoei?th iiaeia iciaeiieoeny a aiaeiioaoei Oa?ueeianueeiai
aea?aeaaiiai iaaee/iiai oiiaa?neoaoo ca aae?anith: 310022, i. Oa?eia
i?iniaeo Eaiiia,4.

Aaoi?aoa?ao ?icineaiee » 27 » ea?oiy 1999 ?ieo

A/aiee nae?aoa? niaoeiaeiciaaii? ?aaee,

eaiaeeaeao iaaee/ieo iaoe, aeioeaio
I.I.Oaiueei

— 1 —

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

AEOOAEUeIINOUe OAIE. Ae?aceiaa oai?iaa oeoieo oa aeaaiaaeoeyoeiaei?
eeoee ? iaaeoi iioe?aiei caoai?thaaiiyi (I.A.Eaaiianeay n niaao.,1987;
G.Lux,1986; S.Munnangi et al.,1997), a eiina?aaoeaia eieoaaiiy ia ni?ey?
iiaiiio aeeieoaaiith oai?eo (TH.I.Iieion n niaao.,1989;
A.A.Oaiooeei,1995; C.Ae.Aoaaa n niaao.,1998; R.Arnold, 1990), i
noi?iaiaeaeo?oueny oneeaaeiaiiyie (A.Ae.A?aoonue n niaao., 1986;
A.I.Neaei?aiei,1994; J.Boey et al.,1990; P.Salvini et al., 1990;
M.Hermansson et al.,1997). Oiio oi?o?ai/ia eieoaaiiy caeeoa?oueny
caniaii eieoaaiiy ae?aceiai? oai?iae, oi/ ia caaaeaee ? aeineiiaeei
(A.N.Iieeieaae/,1994; G.V.Rodkey,1988). ?acaeoeieii niiniae ao?o/aiiy
(A.A.Oaeeiia,A.O.Naaiei,1987; A.O.*a?iionia n niaao.,1995; E.Zilli,1970)
noi?iaiaeaeothoueny cia/iith eaoaeueiinoth oa iiney?acaeoeieieie
?iceaaeaie. I?aaiicaa?iaath/i iia?aoei? (A.E.Aeoaeaiei n niaao.,1987;
A.O.Caeoeaa n niaao.,1995,1998; A.I.?ao/ee, 1997; L.F.Hollender et
al.,1978; V.M.Y.Chan et al.,1994), oi/ i ?iaeoa, aea oaae ia caaaeaee
i?ecaiaeyoue aei aeaeoaeaiiy.

?yae aaoi?ia ii/aee ii?aeioaaoe oi?o?ai/ia eieoaaiiy c oa?aiaaoe/iei, a
iniiaiiio i?e ?acaeoei? oeoieo (A.I.Aonee,1982; L.D.Ducharne et
al.,1975), a a inoaiiie /an i?e i?aaiicaa?iaath/eo iia?aoeiyo
(I.I.Iaaeianeee n niaao.,1986; A.I.Aeieaooei n niaao., 1993), a oiio
/enei ia aeayeeo aoaiao c naiaoi?ii-eo?i?oiei (A.A.Auaiaeia?,1978,1993;
I.I.Iieaaeaiaoe n niaao.,1986). Aeiy ae eo?i?oieo oaeoi?ia
Oaiaeinienueeiai eo?i?oo iiney aaaioiii? acaaaei ia aea/aia.

I?ioa iaeii aaoi?e ia a?aoiaothoue ?iei ia?aaeiia?aoeieii? ?aaaieioaoei?
i i?aaiooue c?iaeoe iia?aoeith o ia?oi 1-3 aeii iiney iaaeoiaeaeaiiy o
noaoeiiia? (A.Ae.Aaeaea n niaao.,1988; A.N.Ecaaiei n niaao., 1988), iioi
— ?icaeyaeathoue ?? iaaoaeoeaiinoue ye iieacaiiy aei ao?o/aiiy
(A.A.Caieyiie,1973; A.I.?aoia?,1997; B.T.Nguyan et al., 1990), a aeayei
canoiniaothoue eeoa i?e noaiici (A.N.Iiiaeia n niaao.,1983) aai i?e
iiaaiiio i?iaiici (A.N.Iieeieaae/ n niaao., 1985). Iiney iia?aoei?
i?ioeae?aceiai caoiaee, yeui i i?iaiaeyoueny, oi cae/aeii ia eiiieaenii
oa eeoa iiney aeienee c oi?o?ai/iiai noaoeiiia?o (O.A.Naeeaaiiaa n
niaao.,1984; A.E.Eoiaeueoeaa n niaao., 1985; TH.A.Ia?oia n niaao.,1995;
N.A.Aaeia n niaao.,1998), /e iiney ia?aaeeeaeueieo aeno?aieo ao?o/aiiue
(A.E.Eoiaeueoeaa n niaao., 1998; A.I.?aaecioianueeee c niiaaao.,1998).
Aieea aea eiiieaeniiai aoaiiiai i?ioeae?aceiaiai eieoaaiiy, aeeth/ath/e
naiaoi?ia, aei iia?aoei?, aaciina?aaeiuei iiney ao?o/aiiy a iiciie oa
aiaeaeaeaiee ia?iiae ia c’yniaaii.

Oi/ i aea/aii aieea aaaioiii? ia caaeeaeaiiy ae?acee(A.I.Iao?iniaa n
niaao.,1981; Z.Michalski et al.,1965), aea ia c’yniaaii aieea
?iciiiaiioieo i?aia?aoia, ui canoiniaothoueny iiney aaaioiii? ia
ii?oiooieoeiiiaeueii ciiie oeoieo. Iaaeinoaoiuei aea/aii aieea ia
aiiainoac oai?iai (ai?iiie, iioiiaeiaoeiie, eiiiie oa iioi iieacieee)
aoaiiiai i?ioeae?aceiaiai ?aaaieioaoeieiiai eieoaaiiy.

Oaeei /eiii, aeneiaeaii ieoaiiy eieoaaiiy oai?eo ae?aceiaith oai?iaith ?
aeooaeueieie oa i?aeoe/ii cia/oueie.

CAssCIE ?IAIOE C IAOEIAEIE I?IA?AIAIE, IEAIAIE, OAIAIE. Aeena?oaoeiy
aeeiiaia caiaeii c ieaiii IAe? E?einueeiai aea?aeaaiiai iaaee/iiai
oiiaa?neoaoo ii.N.I.Aai?ai?anueeiai: iiia? aea?aeaaii? ?aaeno?aoei? UA
01001385 P, oeo? oaie 23.11, oeo? i?iaeaie 22?.

IAOA AeINEIAeAEAIIss — iiaeaeueoe aoaeoeaiinoue oi?o?ai/iiai eieoaaiiy
oai?eo ae?aceiaith oai?iaith oeyoii ?ic?iaee noaie eiiieaeniiai aoaiiiai
eiina?aaoeaiiai, iia?aoeaiiai oa naiaoi?iiai eieoaaiiy.

INIIAII CAAAeAIIss AeINEIAeAEAIIss:

1. Aea/eoe ?acoeueoaoe iia?aoeie o oai?eo ae?aceiaith oai?iaith c
canoinoaaiiyi eiiieaeniiai aoaiiiai eieoaaiiy aei iia?aoei?, a
?aiiueiio, iiciueiio oa aiaeaeaeaiiio iineyiia?aoeieiiio ia?iiaeao.

2. ?ic?iaeoe iiai caniae iia?aoeie ia oeoieo.

3. Aea/eoe aieea ia?aaeiia?aoeieii? oa iineyiia?aoeieii? i?ioecaiaeueii?
?aioaaiioa?aii? aeoii c iiaiaioi?aie oa?iaioia ia ?acoeueoaoe
iia?aoeaiiai eieoaaiiy oai?eo ae?aceiaith oai?iaith.

4. C’ynoaaoe o aenia?eiaioi iniaeeainoi aei? noeioethth/i? ?aaaia?aoeith
oa?aii?, a oaeiae aaiciaaeniiith i o?aioaeo ia e?iaioa/o o oeoieo, o
?aiiie iineyiia?aoeieiee ia?iiae iiney aaaioiii?.

5. Aea/eoe a aenia?eiaioi oa eeiiioei aieea ia nae?aoi?io oa iioi?io
ooieoei? oeoieo iiney aaaioiii? iiia?aeueii? aiaee «Oaiaeinienueea».

6. Aea/eoe ?ieue naiaoi?iiai aoaio icaei?iaeaiiy o eiiieaeniiio
eieoaaiii oai?eo, ui iaee i?aaiicaa?iaath/i iia?aoei?.

7. Aea/eoe ai?iiiaeueiee noaoon oai?eo, noai iioiioaoo oa aeeiaiieo
eiiiiiai? nenoaie iiae aieeaii oi?o?ai/iiai eieoaaiiy oa eiiieaenii?
?aaaieioaoei?.

8. Aea/eoe aeiiiii/io aoaeoeaiinoue, i?aoeacaeaoiinoue i
iiaaeiaeecaoeith oai?eo ae?aceiaith oai?iaith oeoieo oa
aeaaiaaeoeyoeiaei? eeoee iiney oi?o?ai/iiai i aoaiiiai eieoaaiiy.

IAOEIAA IIAECIA ?IAIOE. Aia?oa i?iaaaeaii o E?eio aiaeic caoai?thaaiinoi
ae?aceiaith oai?iaith o oi?o?ai/iiio aniaeoi. ?ic?iaeaii: caniae
oi?o?ai/iiai eieoaaiiy ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee (NIA)
i?e ia?aao Eaoa?aea, ui ia aeeoa?aioeiththoueny (a.n. N 1473754); niinia
?acaeoei? oeoieo (a.n. N 1131494); niiniae ia?iaee «aaaeei?» eoene
aeaaiaaeoeyoeiaei? eeoee (?aoe. i?iiiceoeiy N 273 aiae 18.11.1977 ?. oa
N 1250 aiae 7.01.1985 ?.).

Aia?oa o aenia?eiaioi i?iaaaeaii aea/aiiy aei? i?aia?aoia (iaoeeo?aoeee,
ia?iaie, aano?ioeaiii, o?aioae, aeaea?aii) iiney aaaioiii?. Aeey oeueiai
?ic?iaeaia aenia?eiaioaeueia iia?aoeiy (?aoe. i?iiiceoeiy N 1185 aiae
5.11.1986). Aea/aia aia?oa aeiy aaiciaaeniiith ia e?iaioa/o o oeoieo
iiney NIA.

O aenia?eiaioi oa eeiiioei aia?oa c’yniaaii aieea iiia?aeueii? aiaee
«Oaiaeinienueea» ia nae?aoi?io oa iioi?io ooieoei? oeoieo iiney
aaaioiii? i ?ic?iaeaia aenia?eiaioaeueia iia?aoeiy (a.n. N 833223).

Iieacaii, ui i?iaaaeaiiy eiiieaeniiai eieoaaiiy oai?eo ae?aceiaith
oai?iaith oeoieo oa aeaaiaaeoeyoeiaei? eeoee ia anio aoaiao
?aaaieioaoei?, aeeth/ath/e naiaoi?ia, aeicaiey? inoioii iieiioeoe
?acoeueoaoe oi?o?ai/iiai ao?o/aiiy. Anoaiiaeaii, ui o oai?eo ae?aceith,
oneeaaeiaiith iaiao?aoei?th, i?ioecaiaeueia ?aioaaiioa?aiiy c
iiaiaioi?aie oa?iaioia (?aoe. i?iiiceoeiy N 1251 aiae 7.01.1985) iiaea
aeei?enoiaoaaoeny ye iaoiaaiaoe/iee cania. Aea/aia aeeiaiiea iieacieeia
eiiiiiai? nenoaie, aeayeeo ai?iiiia oa aoii?aeueiiai iioiioaoo iiae
aieeaii oi?o?ai/iiai eieoaaiiy c eiiieaeniith aoaiiith ?aaaieioaoei?th.
Aia?oa aea/aii aeiiiii/iee aniaeo oi?o?ai/iiai eieoaaiiy i?e aoaiiie
eiiieaeniie oa?aii?.

I?AEOE*IA CIA*AIIss IAeA?AEAIEO ?ACOEUeOAOIA. Cai?iiiiiaaii niiniae
aaaioiii?, ?acaeoei? oeoieo, ia?iaee eoene aeaaiaaeoeyoeiaei? eeoee
aeicaieeee iieiioeoe ?acoeueoao oi?o?ai/iiai eieoaaiiy oai?eo
ae?aceiaith oai?iaith. Iiaeoaa?aeaeaia iaiaoiaeiinoue canoinoaaiiy
?acaeoei? oeoieo i?e eieaeicaoei? ae?acee o oeueiio i?aaii /a?ac
iaaaciaeo iaeiaiicaoei?, a i?e o?aaeaiii aeaaiaaeoeyoeiaei? eeoee —
aaaioiii?, a ia?oo /a?ao naeaeoeaii? i?ieneiaeueii? (NIA). Iaa?oioiaaii
iioe?aiiy iieacaiue aei ?? canoinoaaiiy, aeey /iai o?aaa aeei?enoiaoaaoe
NIA aei ?icaeoeo oneeaaeiaiue, i?iaiaeeoe aeiiia?aoeieio i?ioeae?aceiao
oa?aiith, ei?aeoeith aeoiaeaiinoaco iiae /an iia?aoei?, aeei?enoiaoaaoe
aeoiaeaiiieanoeeo, o aeayeeo aeiaaeeao aeeiioaaoe i?e o?aaeaiii
iiaeoeoieiai? caeice, i?e iayaiinoi a aiaiiaci caoeaaiiy i?i?eaii?
ae?acee. Iaiaoiaeii i?e oeueiio aeineiiaei ianoaaeoaaoe oai?eo, aea/aoe
ii?ooaiiy aiiainoaco, aiino ai?iiiia, eiiiiia, noai iioiioaoo c oei, uia
i?iaiaeeoe oeieani?yiiaaio ?o ei?aeoeith aei, oa iiney iia?aoei?.

Eiiieaenia oi?o?ai/ia eieoaaiiy oai?eo ae?aceiaith oai?iaith aei
iia?aoei?, o ?aiiie, iiciie oa aiaeaeaeaiee ia?iiaee aeicaieythoue
iieiioeoe ?acoeueoaoe eieoaaiiy. Iiney aaaioiii? aaaeeeaei aoaiii ?
naiaoi?ia eieoaaiiy, c aeeth/aiiyi ca ?ic?iaeaiith iaie iaoiaeeeith
canoinoaaiiy iiia?aeueii? aiaee «Oaiaeinienueea». I?e i?ecia/aiii ?yaeo
i?aia?aoia iaiaoiaeii a?aoiaoaaoe, ui iiney ia?aneiiaoe/ii? aeaia?aaoei?
?o aeiy iiaea ciiieoeny.

?acoeueoaoe aeineiaeaeaiue cai?iaaaeaeaii o i?aeoe/io ?iaioo c
iiceoeaiei aoaeoii o Niioa?iiieuenueeeo iinueeeo eiea?iyo, o 8 ?aeiiieo
eiea?iyo E?eio oa o 7 iaeanoyo Oe?a?ie, a oaeiae o aeia?eiaioaeueiie
eaai?aoi?i? oiiaa?neoaoo.

Iniiaii iaoeiai iieiaeaiiy aeena?oaoei? aeei?enoiaothoueny o eaeoeieiiio
iaoa?iaei oa ia i?aeoe/ieo caiyooyo ci nooaeaioaie, eiea?yie-iioa?iaie i
eo?naioaie ia eaoaae?ao caaaeueii? oi?o?ai?, oaeoeueoaonueeie oi?o?ai?
oa ia eaoaae?i oi?o?ai? OOE E?einueeiai aea?aeaaiiai iaaee/iiai
oiiaa?neoaoo ii.N.I.Aai?ai?anueeiai.

Ca iaoa?iaeaie aeineiaeaeaiue aeaeaii iaoiaee/ii ?aeiiaiaeaoei? IIC
Oe?a?ie «Yoaiiia ea/aiea aieueiuo ycaaiiie aieaciueth, ia?aianoeo
i?aaiinio?aiythuea iia?aoeee»(Neioa?iiieue,1987), iaea?aeaii 4
iinaiae/aiiy ia ?aoeiiiaeicaoi?nueei i?iiiceoei?, 3 aaoi?nueeeo
naiaeioeoaa ia aeiaoiaee (a.n. N 833223, a.n. N 1131494, a.n. N
1473754).

INIAENOEE AIANIE CAeIAOAA*A. Aeena?oaoeieia ?iaioa ? caaa?oaiei
naiinoieiei aeineiaeaeaiiyi I.E.Aaaaee/a.

Aaoi? aecia/ea iai?yiie ?iaioe, iiaioaaa iaiaoiaeieie iaoiaeeeaie
aeineiaeaeaiiy, noi?ioaaa a?oie iaoei?ioia. Ianoaaeaiiy oai?eo
i?iaaaeaii aeena?oaioii naiinoieii ca o/anoth i?aeoe/ieo eiea?ia
eeiiiee, aano?iaioa?ieiai/iiai aiaeaeieaiiy, eiea?ia Oaiaeinienueeiai
eo?i?oo, i?aoeiaieeia oa aeiiiiiaeieo iiae?icaeieia 7 iinueei? eiea?ii,
eaoaae? aano?iaioa?ieiai? OOE, iaoieiai/ii? aiaoiii? oa aiioiii?
E?einueeiai iaaee/iiai oiiaa?neoaoo ii. N.I.Aai?ai?anueeiai. Aieueoinoue
iia?aoeaieo ao?o/aiue aaoi? aeeiiaa iniaenoi aai anenooaaa i?e ?o
aeeiiaiii. Aenia?eiaioaeueio /anoeio ?iaioe aeena?oaio aeeiiaa o OeIAeE
oiiaa?neoaoo. Aiaeic eioa?aoo?ieo aeaea?ae, iaea?aeaieo
eeiii/ii-eaai?aoi?ieo, iino?oiaioaeueieo oa aenia?eiaioaeueieo aeaieo, a
oaeiae aeneiaeaii o aeena?oaoei? iaea?, iaoeiai aeniiaee c?iaeaii
iniaenoi I.E.Aaaaee/ai. Niiaaaoi?noai aeineiaeieeia o 40 c 56 iaoeiaeo
?iaio iioaeieiaaieo ca iaoa?iaeaie aeena?oaoei?, caeaaieueoiai
aiaeaeca?eaeth? ?o eiinoeueoaoeaii-oaoii/io aeiiiiiao, niiao/anoue o
aeiaaiinoe/ii-eieoaaeueiiio i?ioeani oai?eo ae?aceiaith oai?iaith oa
/anoeiai — o oaenoiaiio aeeeaaei io?eiaieo ?acoeueoaoia aeineiaeaeaiue.

AI?IAAOeIss ?ACOEUeOAOIA AeENA?OAOeI?. ?acoeueoaoe aeineiaeaeaiue ii
aeena?oaoei? aoee aenaioeaii a aeiiiaiaeyo ia caniaeaiiyo E?einueeiai
iaoeiaiai oiaa?enoaa oi?o?aia (1980-1985), iaoeiai-i?aeoe/ieo
eiioa?aioeiyo Oaiaeinienueeiai eo?i?oo (1982,1984), eiioa?aioeiyo
oi?o?aia E?eio — ?aeiiieo (Noaeae,1980; Oaiaeiniy,1988) oa iaeanieo
(1979,1986,1989,1990), ananithciie eiioa?aioei? «Oai?aoe/aneea e
i?aeoe/aneea aniaeou eco/aiey ieoaiey /aeiaaea» (Iineaa,1980), II
ananithciie eiioa?aioei? «sscaaiiay aieaciue aeaeoaeea e
aeaaiaaeoeyoeia?noiie eeoee» (Eo?aai,1988), ieaioiao ananithcii?
i?iaeaiii? eiiini? «Oe?o?aey i?aaiia a?thoiie iieinoe» i?e iaoeiaie
?aaei c oi?o?ai? AII N?N? (Niioa?iiieue, 1988; Iaica,1989 ),
?anioaeieainueeeo eiioa?aioeiyo: «I?eiaiaiea oa?iaioia a
iaaeeoeeia»(Aeoooa,1987); III ?anioaeieainueeie o/aiai-iaoiaee/iie oa
iaoeiaie eiioa?aioei? caaiaeoth/eo eaoaae?aie caaaeueii? oi?o?ai?
iaaeaocia Oe?a?ie (Aiiieoey,1994) i eiio.eao. III-IV ?iaiy ae?aaeeoaoei?
(Iaeana,1998).

IOAEIEAOeI?. Ca iaoa?iaeaie aeena?oaoei? iioaeieiaaii 56 ae?oeiaaieo
i?aoeue (a o./. 10 — a noaooyo o iaoeiaeo aeo?iaeao, 19 — a noaooyo o
cai?ieeao iaoeiaeo i?aoeue, 23 — o iaoa?iaeao i oacao eiioa?aioeie,
c’?caeia), io?eiaii 3 aaoi?nueeeo naiaeioeoaa i?i aeiaoiaee (N 833223, N
1131494, N 1473754), iioaeieiaaii iaeii iaoiaee/ii ?aeiiaiaeaoei?.

NO?OEOO?A E IANssA AeENA?OAOeI?. Aeena?oaoeiy neeaaea?oueny ci anooio, 5
?icaeieia, caaa?oaiiy, aeniiaeia, i?aeoe/ieo ?aeiiaiaeaoeie, nieneo
aeei?enoaieo eioa?aoo?ieo aeaea?ae. Caaaeueiee ianya aeena?oaoei?
noaiiaeoue 469 noi?iiie, ic yeeo 248 noi?iiie caeia? aeania iaoeiiieniee
oaeno. Iaethiee (75), oaaeeoei (104), nienie 996 aeaea?ae eioa?aoo?e
(621 aio/eciyieo oa 375 iiicaiieo) caeiathoue 221 noi?iieo.

C I I N O ? I A I O E

IAOA?IAE I IAOIAeE AeINEIAeAEAIIss

?iaioa a?oioo?oueny ia ?acoeueoaoao eeiiiei-aenia?eiaioaeueieo
aeineiaeaeaiue.

A e n i a ? e i a i o a e ue i a /anoeia ?iaioe i?iaaaeaia ia 4
na?iyo oaa?ei.

Aeey aea/aiiy ii?oieiai/ieo ciii o noiioei oeoieo i aeaaiaaeoeyoeiaei?
eeoee iiae aieeaii aaaioiii? oa oa?iaeieiai/ieo i?aia?aoia,
caaaeaaaeenue iioeiaeaeaiiy (aino?i ae?acee), iienaii N.A.Oaeiiiaei c
niiaaao. (1989).

O i e ? o i e na?i? aeei?enoaii 88 aieeo iaoetheia, ui iiaeieaii ia
5 a?oi: I eiio?ieueia a?oia c 20 oaa?ei — iaea ?aio oeoieo 1,0×0,5 ni;
II a?oia (20 oaa?ei) — noiaao?io aaaioiiith (NOA) i ?aio; III a?oia (20
oaa?ei) — NOA i ?aio, a oaeiae iaea?aeoaaea o?aioae uiaeiy ii 10 ia/ea;
IV a?oia (8 oaa?ei) — naeaeoeaio i?ieneiaeueio aaaioiiith (NIA) i ?aio
oeoieo; V a?oia (20 oaa?ei) — NIA, ?aio i iaea?aeoaaea uiaeiy
iaoeeo?aoeee (30 ia/ea) oa ia?iaie (0,1 ia/ea ). ?acoeueoaoe
ioeiithaaeeny ii aeaeeaa?iinoi oaa?ei oa ianeiaeeao ii?oieiai/iiai
aeineiaeaeaiiy o oa?iiie 3, 5, 7 i 14 aeia iiney iia?aoei?. I?aia?aoe
oa?aoaaeeny aaiaoieneeiiaiceiii, ca aai Aicii, ca Aiii?i, i ca
aeiiiiiaith OEE-?aaeoei?.

Aeey ae ? o a i ? na?i? aenia?eiaioia aeei?enoaii 30 niaae, iiaeieaieo
ia 3 a?oie. Cai?iiiiiaaia noaia iia?aoei? (?aoe. i?iiiceoeiy N 1185 aiae
5.11.1986), iiae /an yei? iaiineeenue ?aie ia ia?aaeith noiieo oiea
oeoieo oa aeaaiaaeoeyoeiaei? eeoee aeiaaeeiith 2,0 ni i ia noiioei
inoaiiuei?, ui i?eeyaaea aei iiaeoeoieiai? caeice, ooai?thaaeany aino?a
«ae?acea» oa?iieaooa?ii aeiaiao?ii 0,4 ni. O anio oaa?ei aeeiioaaeany
NIA. O I a?oii oey iia?aoeiy neoaeeea eiio?ieai, o II — canoiniaoaaeeny
uiaeaiii iiaeoei?ii ii’?eoei? aeaea?aiio a aeici 20 iea/ea, o III —
aano?ioeaiiio a aeici 3 ia/ea.Aeaiaeeee oaa?ei c aeineiaeo oeyoii
caaeeaeaiiy ia?eico o oa?iiie 3, 5, 7, 14, 30 aeia.

O o ? a o i e na?i? aenia?eiaioia aeineiaeaeoaaeany e?iaioa/a o
noiioei oeoieo oeyoii ?a?no?aoei? iai?oae aiaeith a e?iai ca
I.O.Aeai/aieii (1981). Aeei?enoaii 12 eioie. O ieo aoa e?aua
aiaei?aoeueiaaiee oeae niinia aeineiaeaeaiiy. Iaeeaaeoaaany ieaoeiiaee
aeaeo?iae ia eiao oeoieiao aaio, ianeaiee — i?e?aeioaaany aei /a?aaii?
noiiee. Iiey?ia?aoi/ii ?a?no?oaaeany e?eaa eei?aina aiaeith i e?iaioa/a
ae?aaeaeany a ie/100 a/oaeeei. Aii aeii?thaaany aei- oa iiney NIA, aei-
oa iiney aioo?ioiueiaaiiiai aaaaeaiiy aaiciaaeniiith o aeici 0,1 ia/ea
ia 0,5 ie oiciieiai/iiai ?ic/eio, a oaeiae iiney NIA i aaaaeaiiy
aaiciaaeniiith.

* a o a a ? o a na?iy aeineiaeia i?iaaaeaia a oiiaao o?iii/iiai
aeineiaeo ia 14 niaaeao c oinooeith oeoieo aeanii? iiaeeoieaoei? (a.n. N
833223), c yeeo o 10 — c?iaeaia NIA, o 4 — NOA i iiei?iieanoeea ca
Oiiia?i. O aeaio c ieo nia?oo iaeeaaeaia oinooea, a iiney oeueiai
aeeiiaia NIA. Oeoieiaee aiino caae?aany /a?ac oinooeo ca I.I.Eaii?nueeei
(1922) ci ni?iaiei niiaeaieii ca I.E.Iao?iaith i N.I.?ennii (1930).
Iiia?aeueia aiaea «Oaiaeinienueea» canoiniaoaaeany ca 30 oaeeei aei
niiaeaieo a ianyci 50,0-150,0-250,0 ie i?e oaiia?aoo?i 37°N oa 20°N ia
aaciaaia, aaciaaia i o ?iciiiaiioiee /an: 10, 30, 60 oaeeei aei
niiaeaieo, /a?ac 60 oaeeei iiney niiaeaieo i iiaeaieii — ca 60 oaeeei i
/a?ac 60 oaeeei iiney niiaeaieo. Aecia/aee aiaeeio iai?oao nae?aoei?,
caaaeueio eeneioii?iaeoeoeith oa aeaaio-aiaeeio aieueii? nieyii?
eeneioe.

Iiia?aeueia aiaea «Oaiaeinienueea» aiaeiineoueny aei
oei?eaeii-noeueoaoii-iao?i?ai-iaaii?aeo aiae i ii aeaiei oiii/iiai
aiaeico, i?iaaaeaiiio naiaoi?i?i «Ainoiae» 13.03.1989 ?., oi?ioea
I.A.Eo?eiaa aoea neiaeoth/a:

SO4 .61.CL.27(HCO3 .12)

M 4.2 ————————————

(Na+K).56.Ca.24.Mg.20

E e i i i / i a /anoeia ?iaioe aeeiiaia a eeiiioei caaaeueii? oi?o?ai?
ia 693 iaoei?ioao c ae?aceiaith oai?iaith, 217 c yeeo aoee a naiaoi?iyo
iiney iia?aoei?, a o./. o E?eio. E?ii oiai, ia Oaiaeinienueeiio eo?i?oi
aea/aii ca a?oiaieie iaoa?iaeaie 313 iia?iaaieo oai?eo, aeey c’ynoaaiiy
aeioeieueiinoi aeeth/aiiy eieoaaiiy ia oeueiio eo?i?oi, ye aoaio
eiiieaenii? oa?aii?. Oaeei /eiii, niinoa?iaaeiny 1006 /ieiaie.
Aeiaeaoeiai i?iaaaeaii aiaeic caoai?thaaiinoi ae?aceiaith oai?iaith a
E?eio ca 9 ?ieia, ?acoeueoaoia eiina?aaoeaiiai eieoaaiiy 125 oai?eo
ae?aceith aeaaiaaeoeyoeiaei? eeoee i eaoaeueieo eiioeia o i.
Niioa?iiieue ca 4 ?iee, c iaoith aeiaeaoeiaiai iaa?oiooaaiiy
iia?aoeaiiai eieoaaiiy ae?aceiai? oai?iae i, iniaeeai, canoinoaaiiy NIA.

O iniiaiie a?oii ae?aceiaa oai?iaa aeaaiaaeoeyoeiaei? eeoee aoea o 480
(69,26%) c 693 oai?eo, oeoieo — o 183 (26,41%) oa ii?aeiaia ii?acea — o
30 (4,33%). Aie ?o eieeaaany aiae 15 aei 84 ?ieia.

*ieiaieia aoei 582 (83,98%), aeiiie — 111 (16,02%). Aieueoinoue (84,28%)
no?aaeaeaea ae?aceiaith oai?iaith aiae 1 aei 47 ?ieia. Na?aae ieo 88
(12,7%) inia iaee o aiaiiaci caoeaaiiy ia?oi?aoeaii? ae?acee oeoieo (10)
oa aeaaiaaeoeyoeiaei? eeoee (76); e?iaioa/o o aiaiiaci — 85 (12,26%),
aeoiaeaiinoac — 58 (8,36%).

Oai?i iiaeieaii ia inia aac oneeaaeiaiue (290 inia — 41,85%), a
aieueoinoi c aeoeaiith ae?aceith (269 ic 290), i c oneeaaeiaiiyie (403 —
58,15%). Na?aae oneeaaeiaiue noaiic aoa o 128 (18,48%) oai?eo, noaiic c
iaiao?aoei?th — o 136 (19,62%) i iaiao?aoeiy — o 136 (19,62%). O o?ueio
inia c ae?aceith oeoieo, iacaaaeath/e ia aei- i iio?aiia?aoeieia
ainoieiai/ia aeineiaeaeaiiy, i?e inoaoi/iiio aeineiaeaeaiii iiney
iia?aoei? o ae?acoei aeyaeaii aeieueieoei iaeiaiicaoei?.

Ani 693 iaoei?ioe iia?iaaii o ieaiiaiio ii?yaeeo i iiaeieaii ia aeai
i?eaeecii ?iaiioeiiii a?oie. Ia?oa a?oia (iniiaia) c 377 oai?eo
iaea?aeoaaea eiiieaenia aoaiia i?ioeae?aceiaa eieoaaiiy aei iia?aoei?, o
?aiiie, iiciie oa aiaeaeaeaiee iineyiia?aoeieiee ia?iiae, aeeth/ath/e
naiaoi?ia eieoaaiiy o E?eio; ae?oaa a?oia (ii?iaiyeueia) c 316 inia
eiiieaenii? aoaiii? oa?aii? ia io?eioaaea.

I?e iaaeoiaeaeaiii o noaoeiiia? ani oai?i i?ioiaeeee caaaeueii-eeiii/ia,
eaai?aoi?ia oa iino?oiaioaeueia aeineiaeaeaiiy.

Nae?aoi?ia ooieoeiy oeoieo aea/aeanue ca A.W.Kay’?i (1953,1967) c
aeeaiae?ioei?eaeii ainoaiiio o aeici 0,024 ia/ea (TH.I.Oiocii?enn,1972).
Acioaaiaano?ineiiith aeeiioaaee ca aeiiiiiaith oia?ineiiia oi?ie
«Olimpycus» i «EIII», ?aioaaiieiai/ia aeineiaeaeaiiy — ca cae/aeiith
iaoiaeeeith (E.Ae.Eeiaeaia?aoai n niaao.,1976), iioi?io ooieoeith oeoieo
— c aeiiiiiaith aeaeo?iaano?ia?aoi? (AAA) ca I.A.Niaaeiiei (1956)
aia?aoii AAA-4i. Oaieiaicieiee eiio?ieue i?iaiaeeany ca aeiiiiiaith
oaieiaici?a «?oaii 2».

Iioiiaeiaoeiie Ig A, Ig M, Ig G aecia/aee iiaeeoieiaaiei caniaii
G.Mancini et al. (I.A.Einee,1990), iciaeaeo?e/ia oieonoaaiiy (IAO) o
nenoaii aioieiiia (aeaeo?ieioia) oaaaenueei? oi?ie LKB Producter
?iciiiaiioieo aeiaiaciiia ?I a?aaei?ioo — o ai?eciioaeueiiio
aaaaoieiii?eoaaoiio aia?aoi (I.A.Einee,1990). Aecia/aany eiaoioei?io
?iciiaeieo iioiiaeiaoeiiia (E u/e) ye niiaaiaeiioaiiy eoaeieo oa eeneeo
o?aeoeie. Iioiii eiiieaene (IE) aeineiaeaeaii o iieiaoeeai-aeieiei ca V.
Haskow’ith et al. (1978).

Aecia/aiiy ai?iiiia i?iaiaeeeiny ?aaeiiiioiiei caniaii: aano?eio — ca
aeiiiiiaith noaiaea?oiiai iaai?o oi?ie «Sorin» (O?aioeiy); iinoeiio —
iaai?o iinoeoooo aiineioaco (Oai?ueia); oe?aio?iiiio (OOA) — iaai?o
Ria-mat TSH oi?ie «Byk-sangtec», o?eeiaeoe?iiiio (O3), oe?ieneio (O4),
ei?oecieo — ca aeiiiiiaith iaai?ia iinoeoooo aiii?aaii/ii? oiii? ANN?
iaoua i /a?ac 1 aiaeeio iiney noaiaea?oiiai niiaeaieo. Eiiiiiaai,
aieueiee a?aaeeeiiii i aeoeaiinoue eiiiiace aecia/aeeny aiieiai/iei
caniaii (C.R.Diniz et al.,1961; O.N.Ianoeia,1970; I.N.
No?iaueeia,1972,1973).

Cacia/aieie iaoiaeeeaie oai?i ianoaaeoaaeeny aei iia?aoei?, o ?aiiii oa
iiciii iineyiia?aoeieiii ia?iiaei.

Ani ?acoeueoaoe aeineiaeaeaiue ii?aoeueiaaii noaoenoe/ii ca E.A.Ieaiiii
(1960) oa E.N.Eaiiinueeei (1964) c aeei?enoaiiyi AII «Crystal Data».

?ACOEUeOAOE AEANIEO AeINEIAeAEAIUe

O aenia?eiaioi a i a ? o i e na?i? o eiio?iei (I a?oia) aeaeeee 15
iaoetheia, 4 caaeioee iiney ia?eico, 1 — aiae ia?eoiiioo; i?e NOA
aeaeeee 11 c 20, aiae ia?eico caaeioei 4, aiae ia?eoiiioo-5; iiney NIA
caaeaeeo aiae ia?eoiiioo ia aoei, a iiney ia?eico-3 c 8.

A onio 3 a?oiao caaeeaeaiiy o noiioei oeoieo aiaeaoaa?oueny i?eaeecii a
iaeiaeiai oa?iiie, i?ioa iiney NOA aeiaoa caa?iaa?oueny caiaeaiiy,
/anoioa caeeoa?oueny ?aiiaee aeaoaeo i niinoa?iaa?oueny ia?eoiiio, ui
iaoiiaeth? iaioo aeaeeaa?iinoue iaoetheia.

O ianooiiie a?oii iiae aieeaii o?aioaeo iiney NOA c 20 iaoetheia
caaeioei 18: aiae ia?eico — 2, ia?eoiiioo — 16. Aeaeeee o oa?iii aei 14
aeia — 2, oa e o ieo i?e aea/aiii ainoieiai/ieo i?aia?aoia aeyaeeinue,
ui caeeoa?oueny aeaoaeo neeciai? ia /eiaeiio i?ioyci. ?icei
i?iyaey?oueny iiaiie?ia’y, iinoeyie noace, iioieueo?aoeiy a
iiaeneeciaiio oa?i. Iaaii, oea iia’ycaia c oei, ui a oiiaao aaaioiii?,
oa ua ii?ooaiiy aaaeoaoei? i?e iiaiie aeaia?aaoei? oeoieo, aeiy
i?aia?aoo ciiith?oueny, ?aaaia?aoeiy cao?eio?oueny.

O 5 a?oii oaa?ei (NIA i ?aia), canoiniaoaaeenue iaoeeo?aoeee oa ia?iaie.
Caaeioee aiae ia?eico — 5 c 20, iioi aeaeeee.

O ia?oi 3 aeiae ?icieoei c eiio?ieueiith a?oiith ia aoei. Aei 5 aeiae
c’yaeythoueny iiaeiiaieieienoi niieo/iioeaieiii no?oeoo?e, iinoeyie —
iiooaeii io/ee c noaeeiaie oa oia?iaeanoaie, ui aieueo aeyaeythoueny,
iiae o eiio?iei. Aeaoaeo /anoeiai ae?eoee aiioaei?i. Aei 7 aeiae i?e
noeioeyoei? caaeeaeaiiy caeeoa?oueny iacia/ia eaeeioeeoa?ia
iioieueo?aoeiy, iinoea ooeiaeaeaiiy ae?eoa a?oaiaieieienoith
a?aioeyoeieiith oeaieiith, ia eiai iiaa?oii i?ieioa?o? caeiciee
aiioaeie. Aei 14 aeiae ianoa? caaeeaeaiiy «?aie» oeoieo.

Oaeei /eiii, iiney NIA c 5 aeiae iiney iia?aoei? iaoeeo?aoeee oa ia?iaie
i?ecaiaeyoue aei c?inoaiiy oaeaeeinoi ?aaaia?aoei? o noiioei oeoieo.

O ae ? o a i e na?i? aenia?eiaioia ia 3-th aeiao o eiio?ieueieo
oaa?ei (niaae) a onio o?ueio iinoeyo (oeoiie, aeaaiaaeoeyoeiaea eeoea i
aino?a «ae?acea») iayaia caiaeaiiy. Aea iiae aei?th aeaea?aiio o anio 3
ciiao c’yaey?oueny i?ieioa?aoeiy oia?iaeanoia, aiaeioaeith noaeei i
i’yciaeo eeioei, ii e?ath aeaoaeoo — ?aaaia?aoeiy caeic. Ia 5 aeiao
i?iaeiaaeo? iineethaaoenue ?aaaia?aoeaiee i?ioean. Aei 7 aeiae o
eiio?ieueieo oaa?ei ia oiii iciae ?aaaia?aoei?, ui c’yaeeeny,
caeeoa?oueny ?aiiaee aeaoaeo o anio 3 ciiao c yaeuaie caiaeaiiy. O
oaa?ei ui io?eioaaee aeaea?aii o oeoieo c’yaeany ?oaaoeue, o ?aii
aeaaiaaeoeyoeiaei? eeoee oa «ae?acoei» ua caeeoa?oueny aeaoaeo ci
cia/ieie ?aaaia?aoaie i iiaiooai?aieie caeicaie. Ia 14 aeiao ?aiiaee
aeaoaeo o eiio?ieueieo oaa?ei ua ia caaeea o anio 3 ciiao.

O oie aea /an iiae aieeaii aeaea?aiio ?aiiaee eaiae oeoieo caiiaiaiee
?oaoeaaith oeaieiith, aeaaiaaeoeyoeiaei? eeoee caiiiaiee oaiaeioiith
?oaoeaaith oeaieiith, a «ae?aceiaee» aeaoaeo ae?eoee iaeiioa?iaei
oeeeiiae?e/iei aiioaei?i c ?aaaia?aoei?th caeic. Aei 30 aeiae ani
aeaoaeoe ?aaaia?oaaee.

Iaea?aeaii aeaii aecia/athoue aaeeeo noiaeiinoue oa/i? ?aaaia?aoei? o
eiaeiiio aeaoaeoi, a oaeiae oa, ui aeaea?aii i?enei?th? ?aaaia?aoeith, i
oea aeicaiey? eiai ?aeiiaiaeoaaoe aeey ?aaaieioaoei?.

O o?aoie a?oii oaa?ei canoinoaaee aano?ioeaiii. Ia 3 aeiao iiney
iia?aoei? ?aaaia?aoeiy aiaenooiy. Aei 5 aeiae caiaeueia iioieueo?aoeiy
iaio cia/ia o oaa?ei, ui io?eioaaee aano?ioeaiii. O ?aii oeoieo oa
aeaaiaaeoeyoeiaei? eeoee iniothoue a?aioeyoei? i i?ieioa?aoeiy caeiciiai
aiioaeith. Ii aa?aaao ii?ooaiiai i’yciaiai i?ioa?eo oi?iothoueny iiey
neea?ico. O «ae?acoei» aiaecia/a?oueny cia/ia i?ieioa?aoeaia ?aaeoeiy
i’yciaiai i?ioa?eo oa oia?iaeanoia niieo/ii? oeaieie. ?oaoeaaa oeaieia
oi?io?oueny ?aii i oea ia?aoeiaeaeo? caaeeaeaiith iioeiaeaeaiiy. O
eiio?ieueiie a?oii ?aaaia?aoeaii i?ioeane iacia/ii. Aei 7 aeiae
canoinoaaiiy aano?ioeaiiio ia? iinoea ia?aaaaa ?aaaia?aoeaiiai i?ioeano
ii?iaiyii c eiio?ieai a onio 3 ciiao. Ia 14 aeiao o aeineiaeaeaiie a?oii
o oeoieo oa aeaaiaaeoeaoeiaeie eeooei ?aie caaeeee ia aiaeiiio aiae
eiio?ieae. Ia iinoei «ae?acee» caa?iaa?oueny aeaoaeo neeciai?, ae?eoee
caeicieie eiiieaenaie, ui ooai?ththoue 1-2 i?ioa?ee caeic. Aei 30 aeiae
aiaecia/aia iiaia ?aaaia?aoeiy iioeiaeaeaiue ye o aeineiaei, oae i
eiio?iei. Ioaea, i aano?ioeaiii i?enei?th? ?aaaia?aoeith o ?aiii oa?iiie
iiney aaaioiii?.

O o ? a o i e na?i? aeineiaeia ia oaa?eiao aeyaeeiny, ui naeaeoeaia
i?ieneiaeueia aaaioiiiy i?ecaiaeeoue aei cieaeaiiy e?iaioa/i o noiioei
oeoieo ia 37,5±7,4%, i?e aaaaeaiii aaiciaaeniiith a iioaeoieo oaa?ei —
ia 43,4±12,8%, a iiney aaaioiii? — ia 13,3±9,6%, oiaoi oeae i?aia?ao a
oiiaao ia?aneiiaoe/ii? aeaia?aaoei? ciiith? naith aeith — e?iaioa/a ia?
oaiaeaioeith aei caieueoaiiy. Oiio iiney aaaioiii? iaiaoiaeii
a?aoiaoaaoe oaeo ciiie aei? i?aia?aoia.

O / a o a a ? o i e na?i? aenia?eiaioia anoaiiaeaii, ui iiia?aeueia
aiaea «Oaiaeinienueea» ni?e/eiy? iiaeneeaiiy nae?aoei? iiney NIA, yeui
aaeeaa?oueny ca 10 aai ca 30 oaeeei aei ni?iaiiai niiaeaieo. Nae?aoi?ia
ooieoeiy oeoieo cieaeoaaeanue i?e aaeeaaiii aiaee ca 60 oaeeei aei
niiaeaieo /e /a?ac 60 oaeeei i, iniaeeai, i?e iiaeaieiiio canoinoaaiii:
ca 60 oaeeei oa /a?ac 60 oaeeei iiney oa?/iaiai iiae?acieea (?<0,05). Iaia? cia/iiai cieaeaiiy nae?aoei? i?e iaaaeeeiio ianyci aiaee, i?e aaeeaaiii iiia?aeueii? aiaee iecueei? oaiia?aoo?e (20°N). Aaciaaia aiaea iiaeneeth? nae?aoeith. Iiney NOA aiaecia/a?oueny o?ioe aieueoee ?iaaiue nae?aoei?, oi/ aeeiaiiea ciii oaea ae, ye iiney NIA. Iiaeeeai, iiney NOA aaaeoaoi?ia ooieoeiy oeoieo aieueo niiaieueiaia i aiaea i?ecaiaeeoue aei iiae?aciaiiy aano?eii?iaeoeooth/iai aio?aeueiiai aiaeaeieo, ui ni?ey? o?ioe aieueoiio ?iaith nae?aoei? oeoieo, iiae iiney NIA. Iaea?aeaii ?acoeueoaoe iiaeoaa?aeaeaii a eeiiioei o 42 inia, ui ia?aianee iia?aoei? ia oeoieo. I?eeii iiia?aeueii? aiaee ca 60 oaeeei /e /a?ac 60 oaeeei iiney ni?iaiiai niiaeaieo i, iniaeeai, iiaeaieii: ca 60 oaeeei oa /a?ac 60 oaeeei iiney iueiai i?ecaiaeea aei cieaeaiiy nae?aoei? oeoieiaiai nieo iiney aaaioiii? (37 oai?eo). Iiney ?acaeoei? oeoieo (5 inia) oei ciiie aoee ae?aaeaii iaioa. Aeaeo?iiioaioeiaee oeoieo, aea/aii o 80 oai?eo, iiney iia?aoei? c?inoaee i?e caieueoaiii ianyao aiaee. Oieiaeia aiaea, aaciaaia oa aaeeoa ca 10 i 30 oaeeei aei niiaeaieo, iiaeaeuoaaea aeoeaiinoue oeoieo, a ca 60 oaeeei i i?e iiaeaieiiio aeei?enoaiii ca 60 oaeeei oa /a?ac 60 oaeeei iiney iueiai - cieaeoaaea. Oaeei /eiii, iaaaciaaio iiia?aeueio aiaeo "Oaiaeinienueea" aeey i?ioieaeoeee ?aoeeaeeao ae?acee o?aaa aaeeaaoe ii 150,0 ie o oaieiio aeaeyaei (37°N), ca 60 oaeeei /e /a?ac 60 oaeeei iiney ?aei, e?aua iiaeaieii: ca 60 oaeeei oa /a?ac 60 oaeeei iiney ?aei. Iaea?aeaii ?acoeueoaoe aoee aeei?enoaii o i?ioeani eiiieaeniiai oi?o?ai/iiai eieoaaiiy oai?eo ae?aceiaith oai?iaith. Caoai?thaaiinoue ae?aceiaith oai?iaith o E?eio ca 9 ?ieia caieueoeeany c 118,4 aei 185,7 aeiaaeeia ia 10 oen. ianaeaiiy, aea aieueoa o iinoao i ia Iiaaeaiiiio Aa?aci. Eiina?aaoeaia ae eieoaaiiy /anoi ia i?ecaiaeeoue aei aeaeoaeaiiy. Oae, c 125 oai?eo ae?aceith aeaaiaaeoeyoeiaei? eeoee ca 8-10 ?ieia iaeoaeaee eeoa 16 (12,8%) iaoei?ioia, 19 (15,2%) iaee ?iaeei caaino?aiiy, 44 (35,2%) i?iaeiaaeoaaee no?aaeaeaoe /anoeie caaino?aiiyie oai?iae, e?iaioa/aie, a 37 (29,6%) - aoee iia?iaaii, c yeeo 1 iiia? iiney e?iaioa/i (eaoaeueiinoue 2,7%). Iiia?ee aac ao?o/aiiy 9 oai?eo, a oiio /enei aiae iniiaiiai caoai?thaaiiy (e?iaioa/a, iaeiaiicaoeiy ae?acee) -2 (1,6%). Iia?aoeiy o aieueo ?aiiie oa?iii iiaea iieiioeoe ?acoeueoao icaei?iaeaiiy. Oea iiaeoaa?aeaeo? aiaeic eaoaeueiinoi i?e ae?aceiaie oai?iai o i. Niioa?iiiei ca 4 ?iee. Na?aae 97 iiia?eeo, 72 (74,2%) - caaeioee iiney iia?aoei?, i?e/iio a iniiaiiio aiae aeno?aiieo (65), i 25 (25,8%) - aac ia?. Aiie iiia?ee iica oi?o?ai/iei noaoeiiia?ii. Aie iiia?eeo - caeaaieueoiai ia?aaaaeaa 60 ?ieia. ?aiioa aiie ia aoee iai?aaeaii aei oi?o?aa /a?ac iaiieaaeeao eiina?aaoeaio oa?aiith, a iaaeaei - /a?ac noiooii caoai?thaaiiy oa iioeeee aie. O E?eio /enei iia?aoeie ia oeoieo caieueoeeiny ca 9 ?ieia c 938 aei 1238 ca ?ie, c?inea eieueeinoue ieaiiaeo ao?o/aiue ii?iaiyii c aeno?aiieie (1,8:1). Iaeiae o ieiioiie /an /a?ac nioeiaeueii i?e/eie /enei aeno?aiieo iia?aoeie c?inoa?. Caaaeueia iineyiia?aoeieia eaoaeueiinoue i?e ieaiiaeo ao?o/aiiyo ii E?eio neeaea 1,35%, i?e i?i?eaiie ae?acoei - 4,17% i c e?iaioa/ath -11,57%, a ia aenioi e?iaioa/i i?e ?acaeoei? oeoieo - 22,18%. Na?aae ieaiiaeo iia?aoeie eaoaeueiinoue iiney ?acaeoei? oeoieo aoea 1,45%, iiney i?aaiicaa?iaath/eo - 0,79%, a iiney NIA - 0,56%. Ca aeaieie iaoi? eeiiiee, ui aoaea aeeeaaeaii ieae/a, iiney ieaiiaeo i?aaiicaa?iaath/eo ao?o/aiue oa NIA eaoaeueieo ianeiaeeia ia aecia/aii. Ioaea, oi?o?ai/ia eieoaaiiy caeeoa?oueny aaaeeeaei caniaii icaei?iaeaiiy oai?eo ae?aceiaith oai?iaith. Iia?aoeiy iiaeiia aeeiioaaoenue aei ?icaeoeo oneeaaeiaiue o ieaiiaiio ii?yaeeo, c aeei?enoaiiyi caeaaieueoiai i?aaiicaa?iaath/eo ao?o/aiue, iniaeeai NIA. O aieueoinoi aeiaeyiooeo iaie 693 oai?eo ae?aceiaith oai?iaith aoee ciiiaii eaai?aoi?ii iieacieee, aeoeaiinoue eiiiiiai? nenoaie, ai?iiiaeueiee noaooo caeaaieueoiai aaie caieueoaiiy, i?e/iio aieueoa i?e ae?acoei aeaaiaaeoeyoeiaei? eeoee. O oeoieo ia?aaaaeaea aiia?nae?aoeiy. Ana oea aeiaiaeeoue iaiaoiaeiinoue niaoeiaeueii? ia?aaeiia?aoeieii? iiaeaioiaee. Oiio aeaeieaii a?oio c 377 inia, ui neeaea ia?oo (iniiaio) a?oio, a yeie i?iaiaeeeanue aoaiia i?ioeae?aceiaa oa?aiiy o ani ia?iiaee eieoaaiiy. Ia?aaeiia?aoeieiee aoai aeeth/aa aei?oo, i?ioeae?aceiao oa?aiith. Aiia aeiiiaithaaeanue i?ecia/aiiyi iiaiaioi?ia i?ioaac, aiiiieai?iiiai? eeneioe, a i?e iaiao?aoei? ae?acee - i?ioecaiaeueii? ?aioaaioa?aii? c iiaiaioi?aie (?aoe. i?iiiceoeiy N 1251 aiae 7.01.85) oa iiaieaiiiaeo aeieaae. Iiaeiaia eieoaaiiy io?eioaaee 353 oai?eo iniiaii? a?oie: o aano?iaioa?iei/iiio aiaeaeieaiii ia iaioa 3-4 oeaeiia, a o oi?o?ai/iiio - ia iaioa 2 oeaeiia. 24 /ieiaie c 377 oea eieoaaiiy aei iia?aoei? ia io?eioaaee, aea iaaeaei i?iaiaeeeanue eiiieaenia aoaiia oa?aiiy. Oai?i ae?oai? (ii?iaiyeueii?) a?oie (316 c 693) eiiieaenia aoaiia eieoaaiiy ia io?eioaaee. Io?eiaia aeinoiai?ia aoaeoeaiinoue (?<0,01) niaoeiaeueii? iiaeaioiaee. Aiei i?ieoee o 14,06% inia, ui niinoa?iaaeenue, ianoaei iieiioaiiy - o 44,56%, caeeoeeinue aac ciii - o 40,32% i iiai?oaiiy- o 1,06%. O ii?iaiyeueiie a?oii ?acoeueoaoe ai?oi: 1,58%, 26,58%, 67,09% oa 4,75% aiaeiiaiaeii. Iieiioeeenue eaai?aoi?ii aeaii, cieaeoaaeanue aeoeaiinoue eiiiiiai? nenoaie i ciaiooaaeanue nae?aoeiy oeoieiaiai nieo i?e eiai iiaoi?iiio aeineiaeaeaiii aei iia?aoei? (23 oai?eo), a aieueoie ii?i o inia c i?ioeae?aceiaei eieoaaiiyi. Aoaeoeaiinoue eieoaaiiy aoea aeuith i?e o?eaaeinoi eieoaaiiy ia iaioa 3-4 oeaeiia (50,0%), iiae 2 oeaeii (42,0%), i?e aeeth/aiii o eiiieaenio oa?aiith I2-aeieaoi?ia ainoaiiio, aiiaeiii?eio, eiio?eeaeo i, iniaeeai, i?ioecaiaeueii? ?aioaaiioa?aii? o iaeeo aeicao. Inoioiee aoaeo io?eiaii a inoaiiueiio aeiaaeeo o 95,8% oai?eo. Cieceeany aeoeaiinoue eiiiiiai? nenoaie (?<0,05). ?oaoethaaiiy ae?acee ianoaei o 19 (43,2%) inia c 44, ui io?eiaee i?ioeae?aceiaa eieoaaiiy, ciaioaiiy o ?icii?ao - o 15 (34,1%), ae?acea caeeoeeanue iiia?aaeiio ?icii?ia - o 8 (18,2%) i caieueoeeanue - o 2 (4,5%). O eiio?ieueiie a?oii i?e OAN anoaiiaeaii ?oaoethaaiiy ae?acee o 4 (12,9%) oai?eo c 31, ciaioaiiy - o 8 (25,8%), aac aeeiaiiee - o 12 (38,7%) i ae?acea caieueoeeanue - o 7 (22,6%). Iiae /an iia?aoei? ?oaaoeue ia iinoei ae?acee aeyaeaii o 64 (22,2%) c 288 oai?eo ia?oi? a?oie i o 38 (17,0%) - a ae?oaie. O oie aea /an ?icii?e ae?acee iiiaae 3,0 ni /anoioa cono?i/aeenue o ii?iaiyeueiie a?oii (31 /ieiaie-13,8%), iiae a iniiaiie (12 inia 4,2%). Ia?aaeiia?aoeieia iiaeaioiaea aieeaaea i ia aiaeaeaeaii ?acoeueoaoe. Oae, na?aae 349 inia, ui io?eioaaee eiiieaenia eieoaaiiy ia anio aoaiao, iiceoeaii ?acoeueoaoe aecia/aii o 340 (97,4%) i iiaaii - o 9 (2,6%). Na?aae 24 inia, ui ia io?eioaaee aei iia?aoei? eieoaaiiy, a oieueee iiney iia?aoei? - iiceoeaii ?acoeueoaoe aoee eeoa o 21 (87,5%), iiaaii - o 3 (12,5%). Oea aeicaiey? noaa?aeaeoaaoe, ui i?ioeae?aceiaa oa?aiiy aei iia?aoei? ? iaia'yceiaei eiiiiiaioii eieoaaiiy. Iia?aoei? aeeiiaii o ieaiiaiio ii?yaeeo o anio 693 oai?eo. ?acaeoeieii caniae (265-38,24%), caeaaieueoiai ca Aieue?ioii II (141), caeiathoue /eiaea iinoea, ai aeei?enoiaoaaeeny ua aei oe?ieiai ai?iaaaeaeaiiy aaaioiii?. A inoaiii ?iee aiia caeeoa?oueny iia?aoei?th aeai?o i?e ae?acoei oeoieo /a?ac iniaeeainoi iaoiaaiaco oa noeeueiinoi aei iaeiaiicaoei?. I?e ae?acoei aeaaiaaeoeyoeiaei? eeoee aiie aeeiiothoueny i?e iayaiinoi ciii, ui ia?aoeiaeaeothoue aeeiiaiith aaaioiii?. Aeey ciaioaiiy iineyiia?aoeieieo ?iceaaeia iaie ?ic?iaeaii niinia iaeeaaeaiiy eeaiaiiiai aianoiiico (a.n. N 1131494), ui ni?ey? ii?oeieiiio iaaeoiaeaeaiith no?aae o eeoa/iee i iiia?aaeaea? ?aoethen aeia/i o oeoiie. Eiai canoiniaaii o 16 inia. O ieiioiie /an ?acaeoeiy oeoieo aeeiio?oueny caeaaieueoiai ca Aieue?ioii I (124 iniae). I?e ?acaeoei? oeoieo aeaeaey?oueny ae?acea. O 19 oai?eo oea c?iaeoe ia aaeaeiny i aeiaaeiny canoinoaaoe ?acaeoeith "ia aeeeth/aiiy", aea a 2 c ieo ianooieea iaaeinoaoiinoue eoene i iaeei iiia? /a?ac ia?eoiiio. "Noiiiaia" eoena aoea o 17 iaoei?ioia. Canoiniaoaaany aianoiiic ia aeiaaie iaoei c aioa?i-aioa?iaianoiiicii. E?ii oiai, ?ao?ia?aaeii a aeoiaeaioi aaiaeeany oiieee oei?aiiieiaee ciiae aeey ?icaaioaaeaiiy oaia ia eoeni i eeoaany oai ia 4-7 aeiia. Aeey oaeeo aeiaaeeia ?ic?iaeaii aeaa caniae ia?iaee "aaaeei?" eoene i?e iecueeeo aeoiaeaiaeueieo ae?aceao c iaiao?aoei?th i cia/ieie iioieueo?aoeaieie ciiiaie. Ia?oee cania canoiniaaii o 43 oai?eo (?aoe. i?iiiceoeiy N 1250 aiae 7.01.1985). Aeaeiey?oueny aino?i iioieueo?iaaia caaeiy noiiea ia 2-3 ii, caoeaa?oueny iaaeaiei eaoaooii e?icue neeciai-i'yciaee i?ioa?ie. Iaeeaaeathoueny I-iiaeiaii-ia?aiiiii na?icii-i'yciai oae i ae?eaathoueny naeueieeii ia iiaeoei. Iaaeinoaoiinoi eoene ia aoei. Ae?oaee cania (?aoe. i?iiiceoeiy N 273 aiae 18.11.1977) iieyaaa o oiio, ui aeaaiaaeoeyoeiaea eeoea ia?aoeiaeanue aiey i?ieneiaeueiiai aa?aaa iaiao?oth/i? ae?acee. Ia?aaeiie aa?aa eeoee iiaeoeaaany aei aeenoaeueiiai oa ai/ieo aa?aaia ae?acee. Iiney oeueiai na?i-na?icieie oaaie eoena eeoee caoeaaeanue ocaeiaae i ia?eoiiicoaaeanue naeueieeii. NA oa NOA c aeiiiiiith ?acaeoei?th oeoieo aeeiiaia o 75 oai?eo, a iniiaiiio i?e eieaeicaoei? ae?acee o aeaaiaaeoeyoeiaeie eeooei (45). I?e eieaeicaoei? ae?acee o aio?aeueii-iiei?e/iiio aiaeaeiei aiia aeeiiaia oieueee i?e ii?iaeueiiio /e noaii?iaeueiiio ?iaii oeoieiai? nae?aoei? (22). NOA oa NA c iia?aoeiyie, ui ae?aiothoue (58), aeeiioaaeenue /anoioa o ethaeae c oneeaaeiaiiyie ae?aceiai? oai?iae (noaiic oa ii.), i?e iiiai?iinoi iioeiaeaeaiiy ia?aa Eaoa?aea, oyaeeiio caaaeueiiio noaii. A iaio a?oiao ia?aaaaa iaaeaaaeanue NA. Iaiaoiaeii oee?eoey?ii aeaeieyoe no?aaioiae aeey iiaii? aeaia?aaoei? oeoieo. Ae?acea aeoiaeaioi aeaeaeyeanue ia caaaeaee (o 18), a i?e ?? eieaeicaoei? o oeoieo - iaia'yceiai. Iiei?iieanoeea /anoioa aeeiioaaeanue ca Oiiia?i. A iaeiiio aeiaaeeo c?iaeaia naaiaioa?ia ?acaeoeiy oeoieo, o o?ueio naaiaioa?ia ?acaeoeiy aeaaiaaeoeyoeiaei? eeoee. Naeaeoeaia i?ieneiaeueia aaaioiiiy aeeiiaia o 295 oai?eo. Aiia ? iia?aoei?th aeai?o i?e ae?acoei aeaaiaaeoeyoeiaei? eeoee i aiae?iciy?oueny iecueeith eaoaeueiinoth, eaaeei ia?aaiaii iineyiia?aoeieiiai ia?iiaeo oa e?aueie ooieoeiiiaeueieie ?acoeueoaoaie, iniaeeai i?e icieueiaaiie NIA. ?? aeeiiaee o 183 oai?eo, a iniiaiiio i?e ae?acoei aeaaiaaeoeyoeiaei? eeoee (175). I?e oneeaaeiaiie ae?acoei aeei?enoaii ?iciiiaiioii i?eeiie aeey iioe?aiiy iaeanoi canoinoaaiiy NIA. Oae, aianeiaeie eiiieaenii? i?ioeae?aceiai? ia?aaeiia?aoeieii? iiaeaioiaee aaeaeiny ciaioeoe caiaeaiiy i c?iaeoe icieueiaaio NIA o inia ci noaiicii oa noaiicii c iaiao?aoei?th: o 6 oai?eo o ii?aeiaiii c aeoiaeaiieicii, o 2 - c iaeueoeaaei iioe?aiiyi i?ea?aoieea, o 37 - c aeoiaeaiiieanoeeith. O o?ueio /ieiaie c?iaeaia naaiaioa?ia ?acaeoeiy aeaaiaaeoeyoeiaei? eeoee c aeoiaeaii-aeoiaeaiaeueiei aianoiiicii. Ae?acea aeni/aia o 11 inia. Iaeiae, ia caaaeaee aaeaaaeiny aeeiiaoe NIA o oai?eo c aaeeeeie aiaeeeaaeaiiyie aee?o o naeueieeo, ?oaoeaaeie ciiiaie eiai, caiaeueiith iioieueo?aoei?th. Oiio iaie (a. n. N 1473754) ?ic?iaeaii cania eieoaaiiy ae?aceiai? oai?iae (NIA), ui canoinoaaee i?e iiaaii aeeoa?aioeieiaaieo ia?aao Eaoa?aea. O oeeo aeiaaeeao aiaeie?aieth?oueny na?icii-i'yciaee eeaiioue iaei? e?eaecie oeoieo aei aio?aeueiiai aiaeaeieo aeoii c aieeaie aeoeath/iai ia?ao, aeaeiey?oueny no?aaioiae, o?eioothoueny oa ia?aa'ycothoueny ca'ycee oa ia?a ?icaoi, aac eieaiaeaoei? eooo Ainna. C?iaeaia iiaeiaia iia?aoeiy o 9 inia. Icieueiaaia NIA aoea canoiniaaia oaeiae o 5 /ieiaie c ae?aceith oeoieo i o 3 - i?e o?aaeaii oeoieo oa aeaaiaaeoeyoeiaei? eeoee. Ae?acee ia?aaeaeenue aei iia?aoei? aiiini? i aeni/aii. NIA c ae?aioaaiiyi c?iaeaia o 112 inia, /anoioa i?e ae?acoei aeaaiaaeoeyoeiaei? eeoee (108). Aiia aeeiioaaeanue i?e noaiici, aaeeeeo ae?aceao oa c iioeo i?e/ei i iaeaieueo /anoi ii?aeioaaeanue c AAeA ca Aeaeaaoea?i (52) oa iiei?iieanoeeith ca Oiiia?i (42). Ae?acea aeni/aia o 14 inia, a oaeiae o 2 oai?eo c ae?aceith oeoieo i o 2 - i?e ii?aeiaiiio ooeiaeaeaiii. Aeoiaeaiinoac aeyaeaii o 58 inia (I-II nooiaiy - 54, III nooiaiy - 4). I?aaiicaa?iaath/i iia?aoei? aeeiiaii o 42 /ieiaie c aiaeiiiieie oa oi?ioeie ?acoeueoaoaie, a oiio /enei icieueiaaia NIA - o 14 i c iiei?iieanoeeith - o 7 c iecaaaeaiiyi aeaaiaaeoeyoeiaei-?thiaeueiiai aeaeio, NIA c iia?aoei?th ?iaiiniia - o 2, c aeoiaeaii-?thiaeueiei aianoiiicii - o 2, naaiaioa?ia ?acaeoeiy aeaaiaaeoeyoeiaei? eeoee i Ae?A - o 1, a oaeiae aaaioiiiy c aeiiiiiith ?acaeoei?th oeoieo - o 16. O iioeo aeeiiaia ?acaeoeiy ca Aieue?ioii II. Ei?aeoeiy aeoiaeaiinoaco aeicaieeea iioe?eoe aeeiiaiiy aaaioiii?. O aieueoinoi aeiaaeeia (54 - 61,3%) aaeaeiny c?iaeoe i?aaiicaa?iaath/i ao?o/aiiy, a oiio /enei NIA (36), o oai?eo (88 - 12,7%), ui iaee a aiaiiaci caoeaaiiy i?i?eaii? ae?acee. Oaeei /eiii, c 693 oai?eo i?aaiicaa?iaath/i iia?aoei? aeeiiaii o 428 (61,76%). E?ii oiai, o 84 (12,1%) inia c?iaeaii ii?aeiaii ao?o/aiiy c i?eaiaeo noiooiio oi?o?ai/ieo caoai?thaaiue. Iio?aiia?aoeieii oneeaaeiaiiy aoee o 12 (1,73%) /ieiaie: o?aaia naeaciiee o 6, ia/iiee o 1, no?aaioiaeo o 5. Oai?i iaeoaeaee. Iiia?ee iiney iia?aoei? 4 /ieiaiea (0,58%). Ani eaoaeueii eiioei aoee iiney ?acaeoei? oeoieo. Naii iia?aoei? oaea aei eiioey aeeiiaiiy i?ecaiaeyoue aei ciiie eaai?aoi?ieo iieacieeia, iiaeaeuaiiy aeoeaiinoi eiiiiiai? nenoaie (?<0,05), iniaeeai iiney ?acaeoei? oeoieo. Iaioa ?? aeoeaiinoue iiney NIA, iaaii, iia'ycaia c iaioith o?aaiaoe/iinoth oeueiai ao?o/aiiy. Iayaiinoue o neeciaie e?ath ae?acee oeoieo (0,222±0,075 iea/a) oa aeaaiaaeoeyoeiaei? eeoee (0,216±0,104 iea/a) aieueoiai aiinoo eiiiiiaaio o inia, ui io?eioaaee ia?aaeiia?aoeieia eieoaaiiy, ii?iaiyii c oeie, ui ia io?eioaaee eiai (oeoiie - 0,093±0,032 iea/a, aeaaiaaeoeyoeiaea eeoea - 0,087±0,058 iea/a), naiae/eoue i?i ciaioaiiy caiaeaiiy oa i?i iiceoeaiee aieea ia oai?eo i?ioeae?aceiaiai eieoaaiiy. C?aco iiney iia?aoei? e?ii cae/aeieo caoiaeia, ui i?iaiaeyoue anii oai?ei, c o?aooaaiiyi aenia?eiaioaeueiiai aeineiaeaeaiiy, iniaai iniiaii? a?oie i?ecia/aeiny i?ioeae?aceiaa eieoaaiiy, ni?yiiaaia ia ?aaaia?aoeith ae?acee,ui caeeoa?oueny iiney aaaioiii?, oa ia oaeaeoa caaeeaeaiiy aianoiiicia. Oai?i io?eioaaee oiciii?ioeaaeo?e,eieoaaeueio aiiianoeeo. Iniae o ii?iaiyeueiie a?oii eiai ia io?eioaaee. Canoiniaoaaee /a?acciiaeiaa aioa?aeueia oa?/oaaiiy o 193 /ieiaie aeanieie noiioaie, ui aeicaieyei aieueo iiaii eiiiainoaaoe aieeiai (?<0,05) oa aia?aaoe/ii aeo?aoe, ni?eyei aieueo eaaeiio ia?aaiao iineyiia?aoeieiiai ia?iiaeo oa oaeaeoie iiyai ia?enoaeueoeee, ciaioaiith ao?aoe iane oiea, iniaeeai iiney NIA c ae?aioaaiiyi (1,13±0,11 i 1,49±0,13 ea). Ni?eyoeeai aeiya o ?aiiie ia?iiae iiney aaaioiii? aeaea?aii i I2-aeieaoi?e ainoaiiio. O oeeo inia ae?acee caaeeaaee oaeaeoa, cieaeaiiy nae?aoei? oeoieiaiai nieo aoei aieueo iiiioiei. I?ioa, iiney aaaioiii? iiaeooue aeieeaoe iaaaeaeaaoii aiaeiiaiaei ia i?aia?aoe. Oae, iiney aaaaeaiiy aano?ioeaiiio nae?aoeiy oeoieiaiai nieo ciaioeeany o 7 c 10 inia, a o 3 - iiaeaeueeany; iiney ao?iiiio - cieceeany o 7 c 13, a a iioeo 6 - caieueoeeany. Oiio, c o?aooaaiiyi aenia?eiaioo, iiney aaaioiii? e?aua aeei?enoiaoaaoe caniae, ui iiaeneeththoue ?aaaia?aoeith oa ciaioothoue caiaeueiee i?ioean. I?e ?icaeoeo caiaeaiiy ia iinoei aianoiiico (25 inia), iaie?aaoeoi (15), iioieueo?aoi /a?aaii? ii?iaeieie (5), o?iiaioeaaioi (1) aoea aoaeoeaia i?ioecaiaeueia ?aioaaioa?aiiy (44 c 46 oai?eo). Cieaeoaaee aeoeaiinoue eiiiiiai? nenoaie iiney iia?aoei? iiaiaioi?e i?ioaac: eiio?eeae, ai?aeien, aiiaeiii?ei, 5-ooi?o?aoeee. A eiioei eieoaaiiy o oi?o?ai/iiio noaoeiiia?i noai oai?eo iieiioeany. O ia?oie a?oii c eiiieaeniei eieoaaiiyi nea?a ia aoei o 173 inia (45,89%), a o ae?oaie - oieueee o 96 (30,38%). Aieueo iecueei iieacieee nae?aoei? oeoieo aoee o oai?eo iniiaii? a?oie. I?e anio aeaeao iia?aoeie cieaeoaaeenue aeaeo?iiioaioeiaee oeoieo oa aoea ao?aoa iane oiea, aea o iaioie ii?i o inia iiney NIA i oeo, ui io?eioaaee aoaiia eieoaaiiy. Aiaecia/aeany oaiaeaioeiy aei ii?iaeicaoei? ai?iiiia, iioiiaeiaoeiiia oa eiiiiia. I?e ?aioaaiieiai/iiio aeineiaeaeaiii oa oia?iaano?ineiiii o aieueoinoi inia inioaaee oi /e iioi ciiie, aea /anoioa o oeo, ui ia io?eioaaee eiiieaeniiai eieoaaiiy, oi/ aeayei oia?ineiii/ii ciiie, ui cono?i/athoueny /anoioa iiney aaaioiii? (aeaoi?iaoeiy aieiaee, iineyae?aceiaee ?oaaoeue: o 44 c 82 /ieiaie ia?oi? a?oie oa o 9 c 35 - ae?oai?), ia ni?iiiaeii iinaiae/eoe i?i iani?eyoeeai ianeiaeee. Oea naiae/eoue i?i iiceoeaiee aieea eiiieaenii? oa?aii?. I?e oa?iia?aoi? /a?aaii? noiiee o 48 oai?eo aei oeueiai oa?iiio aiaecia/aeiny caieueoaiiy ciie ?icia?iao, ui iia'ycaii c iia?aoei?th i iayaiinoth naiaeiai iineyiia?aoeieiiai ?oaoey. ?iciiiaiioii oneeaaeiaiiy oa ooieoeiiiaeueii ?iceaaee aoee o 148 inia (39,26%) ia?oi? a?oie oa o 199 (62,97%) - ae?oai?, i?e/iio oaei a?icii oneeaaeiaiiy, ye e?iaioa/a, iaaeinoaoiinoue eoene aeoiaeaioi, aaaioa?aoeiy, iiaeaeiao?aaiaeueiee aanoean aecia/aii oieueee o oai?eo, ui ia io?eioaaee niaoeiaeueiiai eieoaaiiy. Oaeei /eiii, eiiieaenia eieoaaiiy a ?aiiueiio iineyiia?aoeieiiio ia?iiaei aeyaey? cia/iee iiceoeaiee aoaeo, i?ioa aeiaaa? o?eaaeinoi aiaeiiaiiai eieoaaiiy. O iiciie iineyiia?aoeieiee ia?iiae niinoa?iaaeeny 376 oai?eo ia?oi? oa 306 - ae?oai? a?oie. C oei?th iaoith iniae iniiaii? a?oie ia?aeeaaeaeeny o aano?iaioa?ieiai/ia aiaeaeieaiiy (365) aai i?iaiaeeeiny eieoaaiiy ia Oaiaeinienueeiio eo?i?oi (8) i aiaoeaoi?ii (3). Oai?i ae?oai? a?oie aiaei?aaeyeenue ia aiaoeaoi?ia niinoa?aaeaiiy. O eiiieaen eieoaaeueieo caoiaeia aeeth/aee aei?oo, iiaiee eo?n i?ioeae?aceiai? oa?aii?, i?eeii iiia?aeueii? aiaee ca 1 aiaeeio aei ?aei i /a?ac 1 aiaeeio iiney ia? oa caoiaee, ni?yiiaaii ia onoiaiiy iineyiia?aoeieieo ?iceaaeia (aeinoaaith, aeia?ath, aeaiiiia neiae?ii oa iioi). Aei eiioey eieoaaiiy caieueoeeiny /enei inia, ui ia iathoue iaoieiai/ieo i?iyaia. Oae, o ia?oie a?oii ?o noaei 257 (68,35%), a o ae?oaie - 142 (46,11%). O oai?eo c aoaiiei eieoaaiiyi, aoea oaiaeaioeiy aei aieueo iecueeiai ?iaiy aieueii? HNL, aieueo ae?aaeaii ii?iaeiciaoaaeenue aeaeo?iiioaioeiaee oeoieo (?<0,05) i ciaiooaaany ?icia?ia /a?aaii? noiiee i?e oaieiaici?iiio ianoaaeaiii (?<0,05). I?ioa oeieeii ?icia?ia ia cieea?. Ana oea iieaco?, ui iaiaoiaeii iiaeaeueoa eieoaaiiy oa aeeniaina?ia niinoa?aaeaiiy. Aei oeueiai oa?iiio ioeiiaia i?aoeacaeaoiinoue oieueee o i?aoethth/eo inia: a ia?oie a?oii o 313 c 376, a ae?oaie - o 202 c 308. Iiaaeiaeecaoei? iiney NIA ia aoei a iaio a?oiao. Iiney iioeo iia?aoeie ?? iaea?aeaee 4 (1,2%) iniae c aoaiiei eieoaaiiyi, a aac iueiai - 9 (4,5%), i?e/iio /anoioa iiney ?acaeoei? oeoieo: o 9 ic 13. O?eaaeinoue iai?aoeacaeaoiinoi neeaea a iniiaiie a?oii 50,3±0,9 aeiia, o ii?iaiyeueiie - 67,3±2,4 aeii i caeaaeaea aiae ?acoeueoaoia eieoaaiiy oa oa?aeoa?o iia?aoei?. Aieueoa aiia aoea iiney ?acaeoei? oeoieo i cia/ii iaioith iiney NIA (?<0,01). Aeiiiii/io aoaeoeaiinoue, /a?ac ?icei ia?aiaaee oeii oa iioeyoeith, iiaeeeai ioeiieoe eeoa o aiaenioeao. Oiio iaie aeei?enoaii ?iaaiue oeii, i?eaaaeaiee o aeo?iaei "Eeiii/ia oi?o?aiy", N 8 ca 1986 ?ie, TH.I.Iieion i A.A.Oeaeeianueeei. Aeiiiii/ii ao?aoe ?ic?aoiaoaaeeny ia iaeiiai oai?iai a iaio a?oiao, ui niinoa?iaaeeny, ca oi?ioeith: AI1 AI = ------------, O aea AI - na?aaeii aeiiiii/ii aeo?aoe ia iaeiiai oai?iai o ea?aiaaioeyo; O - noia anio oai?eo o a?oii; AI1 - noia aeiiiii/ieo aeo?ao eiaeiiai oai?iai, ?ic?aoiaaia ca iiaeeoieiaaiith oi?ioeith TH.I.Iieiona c niiaaao.(1986): AI1 = AeA1 + AA1 + EA + NA2 + AA3, aea Ae - iaoeiiiaeueiee i?eaooie ca iaeei ?iai/ee aeaiue ia iaeiiai i?aoethth/iai; A - uiaeaiii aeieaoe aeiiiiiae ii oei/aniaie iai?aoeacaeaoiinoi; E - aa?oinoue iaeiiai aeiy niinoa?aaeaiiy o oa?aiaaoe/iiio /e oi?o?ai/iiio aiaeaeieaiii; N - aa?oinoue iaeiiai aeiy naiaoi?ii-eo?i?oiiai eieoaaiiy; A - /enei aeiia ia?aaoaaiiy oai?iai a eiaeeo a oi?o?ai/iiio /e oa?aiaaoe/iiio noaoeiiia?i; A1 - /enei ?iai/eo aeiia iiae /an eieoaaiiy; A2 - /enei aeiia eieoaaiiy o naiaoi?i?; A - aa?oinoue aiaoeaoi?iiai aiaeaiaeaiiy oai?ei iiae /an niinoa?aaeaiiy o iieieeiiioei (0,9 ea?aiaaioey ca aeaieie A.O.Aeoeoeiai?, N.O.Onoaaei?ai?,1986); A3 - /enei aiaeaiaeaiue iieieeiieee o ia?iiae ?aaaieioaoei?. AI ii?iaiththoue a iniiaiie i ii?iaiyeueiie a?oiao o aiaenioeao. Aeiiiii/ii ao?aoe aoee iaioi o oai?eo, ui iaee aoaiia eiiieaenia eieoaaiiy: i?e ?acaeoei? oeoieo ia 16,4%, NA oa NOA c ?acaeoei?th - ia 15,2%, NA oa NOA c ae?aioaaiiyi - ia 19,4%, NIA c iiei?iieanoeeith - ia 32,7% oa iaeaieueoee aoaeo ia 35,0% io?eiaii i?e icieueiaaiie NIA. Ioaea, eiiieaenia aoaiia eieoaaiiy i o iiciie ia?iiae ia? icaei?ia/ee aieea ia oai?eo. Ia?aae aeeth/aiiyi naiaoi?iiai eieoaaiiy ia Oaiaeinienueeiio eo?i?oi a aoaiio ?aaaieioaoeith aea/aii ii a?oiaieo iaoa?iaeao 313 inia, ui iaee i?aaiicaa?iaath/i ao?o/aiiy (110) oa ?acaeoeith oeoieo (203). Aeyaeeiny, ui iaee?auee ?acoeueoao icaei?iaeaiiy niinoa?iaaany o inia, ui ia?aianee icieueiaaio NIA. Iiney /iai aiii aeeth/aii ye aoai ?aaaieioaoei? iiney iia?aoeie ia oeoieo c i?eaiaeo ae?aceiai? oai?iae. Na?aae 693 inia, ca yeeie niinoa?iaaee, naiaoi?ia eieoaaiiy io?eiaei 217, i?e oeueiio o aeaeyaei aoaiiiai eieoaaiiy 143, a 74 aoee nea?iaaii o naiaoi?ie c i?eaiaeo iineyiia?aoeieieo ?iceaaeia aac iiia?aaeiuei? eiiieaenii? ?aaaieioaoei?. O ?aiiie ia?iiae (2-4 oeaeii) iiney iia?aoei? iaaeieoee 15 oai?eo, iioi c iniiaii? a?oie - cae/aeii a oa?iiie aiae iaeiiai iinyoey aei iaeiiai ?ieo. Oai?i, ui iaaeoiaeeee o naiaoi?ie aiae?aco iiney aeienee c oi?o?ai/iiai aiaeaeieaiiy, io?eioaaee aa?aaeeeaa eieoaaiiy, o ieo ia canoiniaoaaany aanue niaeo? eo?i?oieo oaeoi?ia. Iioi niinoa?aaeaii iniae io?eioaaee iiaiee eo?n eieoaaiiy. Iiae aieeaii naiaoi?iiai eieoaaiiy o anio iaoeo oai?eo io?eiaii iiceoeaiee aoaeo. Iieiioeany caaaeueiee noai, ae?acee caaeeee, ui aoei aeieacaii ?aioaaiineiii?th oa oia?iaano?ineiii?th. Iieiioeeeny eaai?aoi?ii iieacieee, o aieueoinoi inia ii?iaeicoaaeanue aeoeaiinoue eiiiiiai? nenoaie, i?e/iio iaeaieueo aeneiaeaii iiney NIA. O oeeo oai?eo aiaeiiiii oa aeia?? ?acoeueoaoe aoee o 98,2% aeiaaeeia, a iiney ?acaeoei? oieueee o 88,0%. Oeoieiaa nae?aoeiy iiney aaaioiii? cieaeoaaeany, iiney ?acaeoei? - o?ioe iiaeaeuoaaeany. *enei iaoieiai/ieo ?iceaaeia ciaioeeiny, aea iiney aeaeaeaiiy /anoeie oeoieo ?o ia aoei o 28,0% /ieiaie, ca yeeie niinoa?iaaee, a iiney i?aaiicaa?iaath/eo - o 48,8%, a oiio /enei NIA - o 51,8%. O oie aea /an o?aaa aecia/eoe, ui aieueo aeioeieueii iai?aaeyoe oai?eo ia eo?i?o iiney ?aaaieioaoei? o aano?iaioa?ieiai/iiio aiaeaeieaiii.Oea aeicaieeei a ?i io?eiaoe iiaiee eo?n naiaoi?iiai eieoaaiiy. Naiaoi?ia eieoaaiiy ni?aaey? aieea i ia aiaeaeaeaii ?acoeueoaoe. Oae, o inia c eiiieaeniei aoaiiei eieoaaiiyi, aeeth/ath/e naiaoi?ia, aoei iaioa iiaaieo aeoiaeia (2,0%), iiae o anie ia?oie (iniiaiie) a?oii, ca yeith niinoa?iaaee (3,2%), i o oai?eo c aoaiiei eieoaaiiyi, aea aac naiaoi?iiai (3,9%). Aieueoa iiaaieo ?acoeueoaoia aoei o a?oii inia aac eiiieaeniiai eieoaaiiy, aea o oeo, ui ia?aaoaaee a naiaoi?i? a ca'yceo c aeieeeeie iineyiia?aoeieieie ?iceaaeaie (8,1%). sseui ae aiie ia aoee o naiaoi?i?, oi iiaaii ?acoeueoaou c?inoathoue aei 11,6%. *anoeia iaoeo oai?eo (77) nea?iaoaaeany ia eo?i?oe iiaoi?ii aiae 2 aei 6 ?acia. Iaeaieueo ni?eyoeeai ?acoeueoaoe aecia/aii a inia, ui io?eioaaee eiiieaenia aoaiia icaei?iaeaiiy. Na?aae 52 oai?eo io?eiaii aiaeiiiii aiaeaeaeaii ?acoeueoaoe o 61,5% /ieiaie, aeia?? o 30,8% oa caaeiaieueii - o 7,7%. Iiaaieo aeoiaeia ia aoei. O inia aac aoaiiiai eieoaaiiy, aea oeo, ui iaaeoiaeeee o naiaoi?ie iiaoi?ii, aiaeiiiii ?acoeueoaoe io?eiaii o 19,2% aeiaaeeia, aeia?? - o 50,0%, caaeiaieueii - o 19,2% oa iiaaii - o 11,6%. Iaaeaei oai?i ciaoiaeeeenue ia aeeniaina?iiio niinoa?aaeaiii. Aiaeaeaeaii ?acoeueoaoe aoee aea/aii o 661 oai?iai. Ianoaaeaiiy i?iaaaeaii a oa?iiie: 3-6 iinyoeia, 1 ?ie, 2-3 ?iee, 5 ?ieia, 10 oa iiiaae ?ieia o noaoeiiia?ieo oa aiaoeaoi?ieo oiiaao. Ioeiiea ?acoeueoaoia i?iaiaeeeany ca A.Visick (1948). Aeyaeeiny, ui o aiaeaeaeaiee ia?iiae i?e aoaiiiio eieoaaiii aiaeiiiii oa oi?ioi ?acoeueoaoe aoee o 338 oai?eo (90,6%) c 373, caaeiaieueii - o 23 (6,2%) i iiaaii - o 12 (3,2%), a aac eiiieaeniiai eieoaaiiy - aiaeiiiii oa oi?ioi - o 219 ( 76,0%) c 288, caaeiaieueii - o 38 (13,2%) i iiaaii - o 31 (10,8%). O oie aea /an aiaeiiiii oa oi?ioi ?acoeueoaoe iiney ?acaeoei? aeyaeaii o 86,9% aeiaaeeia, iiney aaaioiii? c aio?oiaeoiii?th - o 90,4%, iiney NA oa NOA c ae?aioaaiiyi - o 83,9%, iiney NIA c iiei?iieanoeeith - o 95,1% i iiney icieueiaaii? NIA - o 91,8%. O inia aac ?aaaieioaoei? aiaeiiaiaeii oei ?acoeueoaoe aoee iiney ?acaeoei? oeoieo o 75,6%, ui niinoa?iaaeeny, aaaioiii? c aio?oiaeoiii?th - o 76,7%, NA i NOA c ae?aioaaiiyi - o 66,7%, NIA c iiei?iieanoeeith - o 81,5%, iiney icieueiaaii? NIA - o 78,7%. Iiaaii ?acoeueoaoe a iniiaiie a?oii aoee aiaeiiaiaeii o 6,0%, 2,4%, 6,4%, 1,2% i 2,2% inia, a o ii?iaiyeueiie - o 10,6%, 10,0%, 16,6%, 11,1% i 8,5% ianoaaeaieo. Iaeiaioa ?o /enei aoei o oai?eo iiney NIA (?<0,05), yei io?eioaaee aoaiia icaei?iaeaiiy. Ia ianeiaeee ia ni?aaeyee inoioiee aieea noaoue, aie, oa?aeoa? i?aoei, aea aiie caeaaeaee aiae aeio?eiaiiy aei?oe (?<0,01), o?eaaeinoi caoai?thaaiiy aei iia?aoeii (5 i aieueoa ?ieia). Oea naiae/eoue i?i iaiaoiaeiinoue oi?o?ai/iiai eieoaaiiy o aieueo ?aiii oa?iiie. ?aioaaiieiai/ii ciiie o ?yaei aeiaaeeia ia aiaeaeaaee ni?aaaeith ea?oeio. Oae, o 21 c 540 ianoaaeaieo aeyaeaii ?aoeeaeea ae?acee oeoieo oa aeaaiaaeoeyoeiaei? eeoee, aea i?e oia?iaano?ineiii? aii ia iiaeoaa?aeaeaiee o 8, a ae?acea aianoiiico - o 2 c 9. A oie aea /an i?e ianoaaeaiii ca aeiiiiiaith oia?iaano?ineiia a iaeiiio aeiaaeeo aeyaeaia ae?acea aeoiaeaioi, ia aeyaeaia ?aioaaiieiai/ii. ?iaaiue aieueii? HNL na?aae 465 ianoaaeaieo aoa cieaeaiee iiney anio iia?aoeie (?<0,01; ?<0,05), aea aiaecia/aany o?ioe aieueo iecueeee ?? aiino iiney eiiieaeniiai aoaiiiai eieoaaiiy. O iaaaeeei? /anoeie oai?eo caeeoa?oueny iaaeinoaoiuei cieaeaiith nae?aoeiy oeoieo: ?acaeoeiy o 2,4% aeiaaeeia, aaaioiiiy c aio?oiaeoiii?th o 2,2%, NA oa NOA c ae?aioaaiiyi o 16,6% i NIA o 3,8%. Oei iniae aoiaeeee aei a?oie ?eceeo i io?eioaaee i?ioe?aoeeaeeaia eieoaaiiy. Ca aeaieie AAA o aiaeaeaeaiee ia?iiae caeeoa?oueny cieaeaiith iioi?eea oeoieo, a aieueoie ii?i iiney ?acaeoei? oeoieo. I?e oaieiaici?iiio aeineiaeaeaiii 54 oai?eo aoei ciaioaiiy ?icia?iao /a?aaii? noiiee o aieueoie ii?i iiney aoaiiiai eieoaaiiy i iiney NIA. Iieacieee iioiiaeiaoeiiia a iaio a?oiao, ui niinoa?iaaeeny, i?aeoe/ii ia aiae?iciythoueny ye iiney ?acaeoei? oeoieo, oae i iiney aaaioiii? i aeecueei aei iieacieeia o caei?iaeo inia. Aea Ig A ai?iaiaeii ieae/a (?<0,05) o oai?eo c aoaiiei eieoaaiiyi. Aiino iioiieo eiiieaenia oa niiaaiaeiioaiiy eoaeieo i eeneeo o?aeoeie (Eu/e) aoei aieueoa ii?ie a iaio a?oiao, ui niinoa?iaaeeny, aea i?e ?aaaieioaoei? ?o ?iaaiue ai?iaiaeii ieae/a, ui naiae/eoue i?i ni?eyoeeaee aieea oeueiai eieoaaiiy. O aiaeaeaeaiee ia?iiae cieaeo?oueny aiino aano?eio (?<0,01) ye iiney ?acaeoei? oeoieo, oae i iiney aaaioiii?. Aea o inia c eiiieaeniei eieoaaiiyi aii aoa aeeae/a aei ii?ie. Iecueeee eiai ?iaaiue o ii?iaiyeueiie a?oii iia'ycaiee c iayaiinoth ao?ioi/iiai aano?eoo. Aoaiia eieoaaiiy ni?eyei iiaeaeuaiith ye aacaeueiiai, oae i noeioeueiaaiiai ?iaiy iinoeiio o ii?iaiyiii c oai?eie aac oeueiai eieoaaiiy. Iaaii, ?aaaieioaoeiy iiaeneeth? o?ioi/iee aieea iinoeiio iiney iia?aoei?. Inio? oaiaeaioeiy aei ii?iaeicaoei? ?iaiy ai?iiiia ueoiaeaeii? caeice oa ei?oecieo, aieueo aiaeaeoa o inia c ?aaaieioaoei?th. Inoaiiie aoa cieaeaiee o ii?iaiyeueiie a?oii o 50,0% inia, o iniiaiie - o 27,7%. Iieacieee eiiiiiai? nenoaie o oai?eo, ui io?eioaaee aoaiia eieoaaiiy, iaaeeaeaeeny aei ii?iaeueieo, iniaeeai iiney NIA. Aac eiiieaenii? ?aaaieioaoei? caeeoathoueny ciiiaieie. Iaoieiai/ii neiioiiieiiieaene iiney ?acaeoeieieo caniaia iia?aoei?, aeeth/ath/e aio?oiaeoiiith c aaaioiii?th, aoee ?iaeoeie i?e aoaiiiio eieoaaiii (47,6%), iiae aac iueiai (61,1%). I?e/iio ?aoeeaeea ae?acee i ae?acea aianoiiico aeyaeaii aiaeiiaiaeii o 3,2% aeiaaeeia oa 4,7%. Iiney i?aaiicaa?iaath/eo iia?aoeie ?iciiiaiioii nea?ae cono?i/aeeny ?iaeoa. Iiney NA oa NOA c ae?aioth/eie ao?o/aiyie i?e eiiieaeniiio eieoaaiii aiie aoee o 48,4% aeiaaeeia, iiney NIA c ae?aioaaiiyi - o 35,8% oa iiney icieueiaaii? NIA - o 34,8%, a aac ?aaaieioaoei? aiaeiiaiaeii: o 83,3%, o 63,0% i o 66,0%. I?e/iio, ?aoeeaeea ae?acee i ae?acea aianoiiico iiney oeeo aeaeia ao?o/aiiy aeyaeaii o 1,7% ianoaaeaieo ia?oi? a?oie oa o 2,9% - ae?oai?. Iaee?aui ?acoeueoaoe aoee iiney NIA. Aei iineyiia?aoeieieo ?iceaaeia iaie aiaeianaii i ii?ooaiiy noaoaai? ooieoei? o /ieiaieia. Aaeeei? ?icieoei o a?oiao ia aoei. Aea oa, ui aiie ianoathoue i?e anio aeaeao iia?aoeie ia oeoieo, ? oaeoii. ?aaaieioaoeieia eieoaaiiy iaei aoaeo o anio 44 oai?eo, ui ia?aianee o aiaiiaci caoeaaiiy i?i?eaii? ae?acee. O a?oii aac ?aaaieioaoei? iiaaii ianeiaeee aeyaeaii o 6 (17,1%) c 35 ianoaaeaieo. Iiney aeoiaeaiiieanoeee i NIA (37) iiaaieo ?acoeueoaoia ia aoei a iaio a?oiao, aea ana-oaee iiney eiiieaeniiai eieoaaiiy aiaeiiiii aeoiaee cono?i/aeeny /anoioa (65,5%), iiae aac iueiai (50,0%). Ia aoei iiaaieo ?acoeueoaoia oaeiae o oai?eo c eeaiaiiei aianoiiicii (16). Iiney NIA o aeaniie iiaeeoeeaoei? o inia c ia?aaie Eaoa?aea, ui ia aeeoa?aioeiththoueny (9 /ieiaie), iacaaeiaieueieo ?acoeueoaoia ia aecia/aii a iniiaiie a?oii, a a ae?oaie aoa ?aoeeaeea ae?acee o iaeiiai oai?iai c o?ueio. Oea aeiaiaeeoue iaiaoiaeiinoue canoiniaoaaoe eiiieaenia aoaiia eieoaaiiy. Inio? iiceoeaiee aoaeo aiae ?aaaieioaoei? - i i?e noiooiueiio iaie?aaoeoi. Aea aii caeaaeaa aiae oa?aeoa?o iia?aoei?. Iiney ?acaeoei? oeoieo ii?aeiaiiy o?iii/iiai iaie?aaoeoo c aeaiiiia neiae?iiii i?ecaaei aei iiaaiiai ?acoeueoaoo a iaeiiai iaoei?ioa. O aiaeaeaeaiee ia?iiae i?aoeacaeaoiinoue aea/aia oieueee o i?aoethth/eo inia: o 344 - ia?oi? a?oie oa o 228 - ae?oai?. Ca /an niinoa?aaeaiiy a?oio iiaaeiaeiinoi iaee 14 (4,7%) /ieiaie iniiaii? a?oie oa 21 (7,3%) - ii?iaiyeueii?. I?ioa, o aieueoinoi aeiaaeeia i?e/eiith iiaaeiaeiinoi aoee noiooii caoai?thaaiiy. Oieueee o 8 inia (3,4%) c 228 ianoaaeaieo aac eiiieaeniiai eieoaaiiy i o 6 (1,7%) - c 344 oai?eo iniiaii? a?oie, i?e/eiith iiaaeiaeecaoei? aoea iia?aoeiy, /anoioa ?acaeoeiy (o 9 c 14). Noaee iainiiia?aie 27 inia ii?iaiyeueii? a?oie i 18 - iniiaii?. Ia aieueo eaaeie i?aoei ciaoiaeeeenue aiaeiiaiaeii 7 oa 11 inia. Eeoa a iaeiiio aeiaaeeo oai?ee iiney ?acaeoei? oeoieo ca Aieue?ioii I i eiiieaeniiai eieoaaiiy ia?aeoia ia aieueo aaaeeo ?iaioo. Iioi i?iaeiaaeoaaee i?aoethaaoe ia oie aea ?iaioi /e ciiieee ?? ia ?iaiioeiiio, oiaoi o iniiaiie a?oii - 312 (90,7%),o ae?oaie - 180 (78,9%) inia. Iiney iia?aoei? oa ?aaaieioaoei? oai?i ciaoiaeeeenue ia aeeniaina?iiio niinoa?aaeaiii, ?i i?iaiaeeeiny i?ioe?aoeeaeeaia eieoaaiiy. I?ioa, iniae c aiaeiiiieie oa oi?ioeie ?acoeueoaoaie i?eoiaeeee ia i?eeii aei eiea?y ia caaaeaee. Aeiiiii/ii aeo?aoe ia iaeiiai oai?iai i?e eiiieaeniie ?aaaieioaoei? o aiaeaeaeaiee ia?iiae aoee iaioi i?e anio caniaao iia?aoeie (?acaeoeiy oeoieo - 52,2%; aaaioiiiy c ?acaeoei?th - 17,4%; CA i NOA c ae?aioth/ith iia?aoei?th - 19,1%; NIA c iiei?iieanoeeith - 87,1% i icieueiaaiith NIA - 128,1%). I?e aiaeici ?acoeueoaoia iia?aoeaiiai eieoaaiiy ae?aceiai? oai?iae ii no?ieao iiney oi?o?ai/iiai ao?o/aiiy, aeyaeeiny, ui /enei iiaaieo ianeiaeeia c?inoaei o ia?oi 3-5 ?ieia, a iaaeaei cieaeoaaeiny. Oea niiaiaaea? c iiaeyaeii aeayeeo aaoi?ia (A.A.Aaaaa n niaao.,1991; T.F.Gorey et al.,1984 ). Ciiiaoe oai?eo c aeeniaina?iiai iaeieo ?aiioa cacia/aiiai oa?iiio ia aeioeieueii. O c a a a ? o a i i i iaiaoiaeii aecia/eoe, ui ca aoaeue-yeeo caniaia iia?aoeie aeioeieueia ?o ii?aeiaiiy c eiiieaeniei aoaiiei icaei?iaeaiiyi. Iaiaoiaeii aoaeoaaoe eiiieaenia aoaiia eieoaaiiy ia oaeie canaaei: ia?oee aoai - eieoaaiiy o aano?iaioa?ieiai/iiio aiaeaeieaiii i?ioyaii 3-4 oeaeiia; iiney oeueiai - ?aoeiiiaeueia oi?o?ai/ia ao?o/aiiy c aeei?enoaiiyi i?aaiicaa?iaath/eo iia?aoeie i, a ia?oo /a?ao, NIA; aiae?aco ae i?iaiaeeoueny ?aiiie aoai eiiieaenii? oa?aii?. Iiney oeueiai caeienith?oueny iiciie aoai ?aaaieioaoei? o aano?iaioa?ieiai/iiio aiaeaeieaiii o?eaaeinoth a na?aaeiueiio 3 oeaeii. Ianooiiee aoai - naiaoi?iee. Iaaeaei iaiaoiaeii aeeniaina?ia niinoa?aaeaiiy c i?ioe?aoeeaeeaiei eieoaaiiyi. Ciiiaoe c aeeniaina?iiai iaeieo oai?eo iiaeia c aiaeiiiieie oa oi?ioeie ?acoeueoaoaie ia ?aiioa 3-5 ?ieia iiney iia?aoei?. Aea yeui o aeayeeo oai?eo c ?icieo i?e/ei aeiaaea? naiaoi?iee aoai eieoaaiiy, oi ani iioi iiaeiii i?iaiaeeoeny. Ani oei caoiaee aeicaieythoue iieiioeoe aiaeaeaeaii ?acoeueoaoe oi?o?ai/iiai eieoaaiiy oai?eo ae?aceiaith oai?iaith. A E N I I A E E 1. Cai?iiiiiaaiee cania eiiieaeniiai aoaiiiai eieoaaiiy aeeth/a? aeiiia?aoeieia i?ioeae?aceiaa eieoaaiiy, ?aoeiiiaeueia oi?o?ai/ia ao?o/aiiy, aaaeaii i?aaiicaa?iaath/a, ?aiith iineyiia?aoeieio i?ioeae?aceiao oa noeioethth/o oa?aiith i aieueo iicith , ia?aaaaeii o aano?iaioa?ieiai/iiio aiaeaeieaiii /e naiaoi?i?, a o aiaeaeaiaiiio ia?iiaei - naiaoi?ia eieoaaiiy oa aeeniaina?ia niinoa?aaeaiiy. 2. Naeaeoeaia i?ieneiaeueia aaaioiiiy i?e ae?aceiaie oai?iai aeaaiaaeoeyoeiaei? eeoee o ieaiiaie oi?o?ai? iiaeia caeeoaoeny iia?aoei?th aeai?o ic-ca iiiiiaeueii? eaoaeueiinoi oa e?aueo ooieoeiiiaeueieo aeoiaeia. Naeaeoeaio oa noiaao?io aaaioiiith neiae canoiniaoaaoe i?e oneeaaeiaiiyo ae?aceiai? oai?iae oa oyaeeeo noiooiio caoai?thaaiiyo. 3. I?e ae?aceiaie oai?iai oeoieo iia?aoei?th aeai?o ? ?acaeoeiy oeoieo, i?e/iio e?aui ?acoeueoaoe aea? niinia ?acaeoei? ca Aieue?ioii I, a o iiaeeoieaoei? Aieue?io II - canoinoaaiiy eeaiaiiiai aianoiiico, yeee aeicaiey? oieeiooe i?iyaia aeaiiiia neiae?iio i ?aoethen aano?eoo. 4. Oaeineiiaeaiiy oaoii/ieo caniaia i?e iia?aoeiyo c i?eaiaeo ae?aceiai? oai?iae, ye-oi: oi?iaaaeaeaiiy iiaeo iiaeeoieaoeie NIA, eeaiaiiiai aianoiiico, ia?iaee eoene aeaaiaaeoeyoeiaei? eeoee, a oaeiae aieueo oe?iea canoinoaaiiy aeoiaeaiiieanoeee, ei?aeoei? aeoiaeaiinoaco aeicaiey? iieiioeoe ?acoeueoaoe iia?aoeie. 5. I?ioeae?aceiaa oa?aiiy a ia?aaeiia?aoeieiee ia?iiae, iniaeeai ae o ii?aeiaii c i?ioecaiaeueiith ?aioaaioa?aii?th, aeicaiey? iioe?eoe iieacaiiy aei NIA oa iioeo i?aaiicaa?iaath/eo iia?aoeie. 6. O aenia?eiaioi aaaioiiiy oyaia ca niaith ciiiaio ?aaeoeith i?aaiicio ia iaaeeeaiaioicii i?aia?aoe i, anoia?a/ i/ieoaaiiiio ?acoeueoaoo, iiney NOA ii?ooaiiy iie?ioee?eoeyoei? iiae aieeaii o?aioaeo iineeththoueny, a iiney NIA aaiciaaeniiie i?enei?th? e?iaioa/o o oeoieo, ui iaiaoiaeii a?aoiaoaaoe a iineyiia?aoeieiiio ia?iiaei. 7. Iiia?aeueia aiaea iinoeaaiai Oaiaeinienueeiai eo?i?oo ia? caeaoiinoue i?eaii/oaaoe oeoieiao nae?aoeith i ?? aeeoa?aioeieia canoinoaaiiy o ii?aeiaii c iioeie eo?i?oieie oaeoi?aie o inia, ui iaea?aeaee naiaoi?ia eieoaaiiy, aeicaiey? ciaioeoe o 4 ?ace eieueeinoue iacaaeiaieueieo aeoiaeia o aiaeaeaeaiee ia?iiae. 8. Eiiieaenia aoaiia oa?aiiy oai?eo ia ae?aceiao oai?iao i?e canoinoaaii iioeiaeueiiai caniao oi?o?ai/iiai eieoaaiiy, ye iniiaiiai, aeicaiey? ciaioeoe eieueeinoue iacaaeiaieueieo aeoiaeia c 10,8% aei 3,2%, a iiaaeiaeecaoeith iia?iaaieo inia c 4,4% aei 1,28%. O oa?iii niinoa?aaeaiiy iiney 10 ?ieia iacaaeiaieueieo aeoiaeia ia aiaecia/aeiny. 9. Eiiieaena eieoaaiiy aea? iiaeeeainoue cieceoe oei/aniao iai?aoeacaeaoiinoue iiney NIA ia 25,0% i aeo?aoe ia iaeiiai oai?iai aei aiaeiiaeaiiy i?aoeacaeaoiinoi ia 35,0%, a iiney ?acaeoei? oeoieo ia 16,4%. O aiaeaeaeaiee ia?iiae, aianeiaeie ciaiueoaiiy eieueeinoi iineyiia?aoeieieo ?iceaaeia, oei aeo?aoe ciaiueoothoueny iiney NIA ia 128,1%, iiney ?acaeoei? oeoieo ia 52,2%. 10. Ai?iiiaeueiee noaoon oai?eo (aano?ei, iinoeei, ei?oecie, ai?iiie ueoiaeaeii? caeice), aoii?aeueiee iioiioao oa eiiiie, ia?iaii c iioeie oanoaie, iiaeooue aooe e?eoa?iyie aeaeoaeaiiy i naiae/eoe i?i iiaeeeainoue ciyooy oai?eo c aeeniaina?iiai niinoa?aaeaiiy. NIENIE I?AOeUe, IIOAEIEIAAIEO CA OAIITH AeENA?OAOeII 1. Aaaaee/ A.E., Oanaiei A.I. Iieacaoaee eeieiiaie nenoaiu i?e iaeioi?uo caaieaaaieyo i?aaiia a?thoiie iieinoe // Eeei. oe?o?aey.- 1981. N 8. - N.24-26. 2. Aaaaee/ A.E., Oanaiei A.I., Noaiaiia I.I. Eeieiu e?iae i?e caaieaaaieyo i?aaiia a?thoiie iieinoe // Aano. oe?o?aee ei. E.E.A?aeiaa. - 1981. - N 8. - N.33-35. 3. Oanaiei A.I., Aaaaee/ A.E., Noaiaiia I.I., Eeeoaae/ E.A. Eciaiaiea eeieiiaie nenoaiu i?e oe?o?ae/aneeo caaieaaaieyo // Oe?o?aey. - 1982. - N 10. - N.65-68. 4. Aaaaee/ A.E., Oanaiei A.I. Eeieiu e?iae e eiaeaeoi?iay oa?aiey i?e ycaaiiie aieacie // Oe?o?aey. - 1984. - N 9. - N.75-77. 5. Aieiaoaa I.I., Oanaiei A.I., Aaaaee/ A.E., A?oaiia TH.A., Aee Ea?aia Aei Oaeea, Eiiiiaiei A.E. Nio?aiaiea i?ea?aoieea i?e iia?aoeaiii ea/aiee ycaaiiie aieacie // Nia. iaae.- 1986. - N 2. - N.102-104. 6. Oanaiei A.I., Oanoiiaeia Ae.A., Aaaaee/ A.E. Eeaiaiiue aano?i-yioa?iaianoiiic, eae ia?a i?ioeeaeoeee iinoaano?i?acaeoeeiiiiai neiae?iia // Oe?o?aey. - 1989. - N 8. - N.121-122. 7. Aaaaee/ A.E. Ioaeaeaiiua ?acoeueoaou eiiieaeniiai oe?o?ae/aneiai ea/aiey aieueiuo n ycaaiiie aieaciueth // Aanoiee oe?o?aee ei. E.E.A?aeiaa. - 1998. - O.157, ? 3. - N.65-67. 8. Aaaaee/ A.E. 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Iiaeathoueny ?acoeueoaoe eiiieaeniiai aoaiiiai eieoaaiiy, aeeth/ath/e naiaoi?ia iiae /an oi?o?ai/ieo ao?o/aiue oa aieea eiai ia eeiii/ii, eaai?aoi?ii, iioiieiai/ii, ai?iiiaeueii oaeoi?e, aeoeaiinoue eiiiiia oa ia'aeoeaii iino?oiaioaeueii e?eoa?i?. ?ic?iaeaii iiai aoaeoeaii caniae iia?aoeie, cai?iiiiiaaia iaoiaeeea eiiieaeniiai aoaiiiai eieoaaiiy, yei iieiioothoue aiaeaeaeaii ?acoeueoaoe, ciaioothoue oei/aniao iai?aoeacaeaoiinoue, iiaaeiaeecaoeith oai?eo i aeathoue aeiiiii/iee aoaeo. I?iaiaeii ?acoeueoaoe aeena?oaoei? ciaeoee i?aeoe/ia ai?iaaaeaeaiiy i?e eieoaaiii oai?eo ae?aceiaith oai?iaith. Eeth/iai neiaa: ae?aceiaa oai?iaa, cania iia?aoei?, eiiieaenia aoaiia eieoaaiiy, ai?iiie, iioiioao, aeiiiii/iee aoaeo. AIIIOAOeEss Aaaaee/ A.E. Yooaeoeaiinoue eiiieaeniiai oe?o?ae/aneiai ea/aiey aieueiuo ycaaiiie aieaciueth. - ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie aeieoi?a iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.03 - oe?o?aey. - Oa?ueeianeee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao IC Oe?aeiu, Oa?ueeia, 1999. Caueuaaony iao/iay ?aaioa, iaiauathuay ?acoeueoaou yenia?eiaioaeueiuo enneaaeiaaiee e oe?o?ae/aneiai ea/aiey 693 aieueiuo ycaaiiie aieaciueth aeaeoaeea e aeaaiaaeoeaoeia?noiie eeoee. Aia?aua eco/aia caaieaaaaiinoue yoie aieaciueth a oe?o?ae/aneii aniaeoa a E?uio e auyniaii, /oi /aua aieatho ethaee a ai?iaeao e ia THaeiii Aa?aao e iiaeoaa?aeaeaii, /oi eo/oea ?acoeueoaou ioia/athony iinea i?aaiinio?aiythueo aiaoaoaeuenoa. Iiyoiio ?anoe?aiu iieacaiey e eo i?eiaiaieth iooai ei??aeoeee aeoiaeaiinoaca, i?iaaaeaiey i?aaeiia?aoeeiiiiai ea/aiey, i?eiaiaiey aeoiaeaiiieanoeee, o eeoe ia?aianoeo ooeaaiea i?iaiaeiie ycau. ?ac?aaioaiu iiaua yooaeoeaiua niiniau iia?aoeee: naeaeoeaiay i?ieneiaeueiay aaaioiiey (NIA) i?e iaaeeooa?aioee?othueony ia?aao Eaoa?aea; eeaiaiue aianoiiic i?e ?acaeoeee aeaeoaeea ii Aeeue?io II; iaoiaeu ia?aaioee "o?oaeiie" eoeueoe aeaaiaaeoeaoeia?noiie eeoee. Oia?ei 4 aieueiuo (0,57%) iinea ?acaeoeee aeaeoaeea. Eaoaeueiinoe iinea i?aaiinio?aiythueo aiaoaoaeuenoa ia auei. A yenia?eiaioa aia?aua iainiiaaii i?eiaiaiea iinea aaaioiiee n?aco iinea iia?aoeee i?ioeaiycaaiiie oa?aiee. Iaoeeo?aoeee, ia?iaie, aano?ioeaiei, aeaea?aeth niinianoaotho oneeaieth ?aaaia?aoeee iano iia?aaeaeaiee, /oi auei eniieueciaaii i?e ea/aiee aieueiuo. Iaeiaei o?aioae e aaiciaaeniiee iinea aaaioiiee eciaiytho nai? aeaenoaea e yoi iaiaoiaeeii o/eouaaoue a iineaiia?aoeeiiiii ia?eiaea. I?aaeeiaeaia iaoiaeeea i?iaeieaeaiiiai eiiieaeniiai yoaiiiai i?ioeaiycaaiiiai ea/aiey aieueiuo aei iia?aoeee, n?aco iinea aiaoaoaeuenoaa, a iicaeiee e ioaeaeaiiue ia?eiaeu, aeeth/ay naiaoi?iue ia Oaiaeineeneii eo?i?oa, n aeeniaina?iui iaaethaeaieai. Aeey yoie oeaee iaoeeaiou aeieaeiu i?ieoe i?aaeiia?aoeeiiiia i?ioeaiycaaiiia ea/aiea a oa/aiee ia iaiaa 3 iaaeaeue i?aaeii/oeoaeueiaa a aano?iaioa?ieiae/aneii noaoeeiia?a; ?aoeeiiaeueiia oe?o?ae/aneia aiaoaoaeuenoai; n?aco iinea iia?aoeee, ia?yaeo n iau/iuie iineaiia?aoeeiiiuie ia?ii?eyoeyie, i?ioeaiycaaiiay oa?aiey e /?acciiaeiaia yioa?aeueiia ieoaiea; i?iaeieaeaiea ea/aiey a aano?iaioa?ieiae/aneii noaoeeiia?a aei 3 iaaeaeue, ?aaea - aiaoeaoi?ii; naiaoi?iia ea/aiea e aeeniaina?iia iaaethaeaiea. A neo/ayo, eiaaea naiaoi?iue yoai auiaaeaao, inoaeueiua aeieaeiu niaethaeaoueny. Aia?aua aeieacaii, /oi ea/aiea ia Oaiaeineeneii eo?i?oa yaeyaony yooaeoeaiui ia oieueei iinea ?acaeoeee aeaeoaeea, ii e iinea aaaioiiee, iniaaiii anee iii eniieuecoaony eae yoai eiiieaeniie oa?aiee. Ia iiaeaee o?iie/aneiai iiuoa, i?aaeeiaeaiiiai aaoi?ii, ?ac?aaioaia iaoiaeeea i?eaia ieia?aeueiie aiaeu "Oaiaeineeneay" iinea aaaioiiee,/oi iicaieyao iiaeaea?aeeaaoue nae?aoeeth aeaeoaei/iiai niea ia ieceii o?iaia e neoaeeoue i?ioeeaeoeeie ?aoeeaeeaa ycau. Yoaiiia ea/aiea ieacuaaao nouanoaaiiia aeeyiea ia eeeie/aneea, eaai?aoi?iua e eino?oiaioaeueiua e?eoa?ee. Ec eiioiiaeiaoeeiia aieueoa oaaee/eaathony eiioiiaeiaoeei G, eiioiiua eiiieaenu e uaei/ii-eeneioiue eiyoeoeeaio. Iineaaeiea aeaa inoathony iiauoaiiuie e a ioaeaeaiiue ia?eiae, i?aeiouanoaaiii o eeoe aac yoaiiiai ea/aiey. Aano?ei iinea iia?aoeee oiaiueoaaony a aieueoae noaiaie iinea ?acaeoeee aeaeoaeea. Iaee/ea aai a e?iae iinea oaeaeaiey aio?aeueiiai ioaeaea, aiai?eo e i aai aiaaeaeoaei/iii i?ienoiaeaeaiee. Eciaiyaony oaeaea i?e yoaiiii ea/aiee niaea?aeaiea einoeeia, ai?iiiia ueoiaeaeiie aeaeacu, ei?oeciea. A aieueoae noaiaie nieaeaaony aeoeaiinoue eeieiia (a?aaeeeeiei, eeieiiaai, eeieiaca) i?e oeacaiiie oa?aiee, iniaaiii iinea NIA. Cia/eoaeueii ?aaea ioia/athony eciaiaiey i?e oea?iaano?ineiiee, ?aioaaiineiiee, yeaeo?iaano?ia?aoee, oaieia?aoee. Iineaaeiee iaoiae aieaa eioi?iaoeaai a ioaeaeaiiue ia?eiae iinea iia?aoeee. I?aaeeiaeaiiay iaoiaeeea yoaiiiai oe?o?ae/aneiai ea/aiey aeinoiaa?ii (?<0,01) oeo/oaao ioaeaeaiiua ?acoeueoaou. Ii A.Visick (1948) ioee/iua enoiaeu auee a 59,5% neo/aaa, oi?ioea - a 31,1%, oaeiaeaoai?eoaeueiua - a 6,2% e ieioea - a 3,2%. Aac yoiai ea/aiey auee niioaaonoaaiii: a 36,1%, 39,9%, 13,2% e 10,8%. Yoaiiay oa?aiey oiaiueoeea a?aiaiioth iao?oaeiniiniaiinoue n 67,3 aeiae aei 50,3 aeiae; eiaaeeaeecaoeeth aieueiuo c 3,4% aei 1,7% e yeiiiie/aneea iioa?e a ioaeaeaiiue ia?eiae ia 17,4 - 128,1%, iniaaiii iinea NIA. Iniiaiua ?acoeueoaou aeenna?oaoeee iaoee i?aeoe/aneia i?eiaiaiea i?e ea/aiee aieueiuo ycaaiiie aieaciueth e eceiaeaiu a 56 ia/aoiuo ?aaioao. Eeth/aaua neiaa: ycaaiiay aieaciue, niinia iia?aoeee, eiiieaeniia yoaiiia ea/aiea, ai?iiiu, eiioieoao, yeiiiie/aneee yooaeo. SUMMARY Babalitch A.K. Effectiveness of the complex surgical treatment of patients with ulcer disease. - Manuscript. Thesis for getting Doctor of Medical Sciences' Degree by speciality 14.01.03 - Surgery.- Kharkov State Medical University. Kharkov, 1999. The scientific investigation summarizes the results of experimental examination and treatment of 693 patients with ulcer disease. The author states the results of the complex stage treatment, including health resource treatment in the cases of surgical invasions and its influence on clinical, laboratory, immunological, hormonal factors, kinins activity and objective instrumental criteria. In the process of investigation the new effective methods of operations were worked out, the new methods of complex stage treatment were suggested, which improve the remote results, desrease the temporary disability and invalidity of patients and give a certain economical effect. The main results of this work have been already used in the treatment of patients with ulcer disease. Key words: ulcer disease, method of operation, complex stage treatment, hormones, immunity, economical effect.

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