Діагностика фазного шлункового кислотоутворення та лікування фазних гастродуоденальних дискінезій у хворих на виразкову хворобу дванадцятипалої кишки:

I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

CAII??CUeEEE AeA?AEAAIEE IAAeE*IEE OI?AA?NEOAO

E?AICA? Ieaenaiae? Ieaenaiae?iae/

OAeE 616.342-002.44-07-085

Ae?AAIINOEEA OACIIAI OEOIEIAIAI

EENEIOIOOAI?AIIss OA E?EOAAIIss OACIEO

AANO?IAeOIAeAIAEUeIEO AeENE?IAC?E O OAI?EO IA AE?ACEIAO OAI?IAO
AeAAIAAeOessOEIAEI? EEOEE

14.01. 02 – aioo??oi? oai?iae

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Caii??aeaey – 1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia o Caii??cueeiio ?inoeooo? oaeineiiaeaiiy e?ea??a,

IIC Oe?a?ie.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe, i?ioani?

?AOAO?EIA TH??e ?aaiiae/,

Caii??cueeee ?inoeooo oaeineiiaeaiiy e?ea??a,

caa?aeoaa/ eaoaae?e aano?iaioa?ieia??

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani? AACAI?IAeUeEI Ai?en Ieeieaeiae/

Caii??cueeee aea?aeaaiee iaaee/iee oi?aa?neoao, i?ioani? eaoaae?e

oaeoeueoaonueei? oa?ai??;

aeieoi? iaaee/ieo iaoe, i?ioani? A?EOeAIEI ?aai ?aaiiae/

Aei?i?iiao?ianueea aea?aeaaia iaaee/ia aeaaeai?y, caa?aeoaa/ eaoaae?e

aano?iaioa?ieia?? oa ee?i?/ii? ae??oieia??.

I?ia?aeia onoaiiaa:

?inoeooo oa?ai?? AII Oe?a?ie, a?aeae?e aano?iaioa?ieia?? (i. Oa?e?a).

Caoeno a?aeaoaeaoueny “ 26 ” n?/iy 2000 ?ieo i 13 aiaeei? ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee Ae 17.600.02 o Caii??cueeiio aea?aeaaiiio
iaaee/iiio oi?aa?neoao? ca aae?anith: 69035, i. Caii??aeaey, i?.
Iayeianueeiai, 24.

C aeena?oaoe??th iiaeia iciaeiieoenue a iaoeia?e a?ae?ioaoe?
oi?aa?neoaoo (69035, i. Caii??aeaey, i?. Iayeianueeiai, 26.)

Aaoi?aoa?ao ?ic?neaiee “24” a?oaeiy 1999 ?ieo.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe, i?ioani? Aieioei I.A.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. I?iaeaia no/anii? ae?aaiinoeee oa aoaeoeaiiai
e?eoaaiiy ae?aceiai? oai?iae aei oeueiai /ano caeeoa?oueny aeooaeueiith.
A aaaaoueio e?a?iao na?oo, a oiio /ene? ? a Oe?a?i?, ia? i?noea
i?aeaeuaiiy caoai?thaaiino? ae?aceiaith oai?iaith o ethaeae ??ciiai
a?eo, a oaeiae e?eueeino? ?? /anoi ?aoeeaeeaoth/eo ? o?aciaieo oi?i, ye?
/anoi i?aeeyaathoue o??o?a?/iiio e?eoaaiith (Ia?aaea??e A.A., 1998).

Iacaaaeath/e ia aaeeeee oni?o aano?iaioa?ieia?? o e?eoaaii? ?
ae?aaiinoeoe? oeueiai caoai?thaaiiy, aaaaoi ieoaiue ao?ieia?? oa
iaoiaaiaco ae?aceiai? oai?iae caeeoathoueny iac?icoi?eeie. Iaiaeiicia/ia
noaaeaiiy aei ao?ieia?? oa iaoiaaiaco ae?aceiai? oai?iae aeiaaa? iiooeo
iiaeo niinia?a ae?aaiinoeee ? e?eoaaiiy oeueiai caoai?thaaiiy.

Aaaaoi aaoi??a (Oeeiia?iai ss.N., 1991, A?eai?ueaa I.ss., A?eoeaiei
E.E., 1995, Aeaaoy?aaa E.E., Oa?/aiei I.A., 1995; oa ?i.) aeacothoue ia
/anoa ii?aeiaiiy ae?aceiai? oai?iae c ?ioeie ii?ooaiiyie
oeoieiai-eeoeiaiai o?aeoo. I?ae iniiaiei ? noiooi?i caoai?thaaiiyi
ia??aeei aeieeathoue iaoiaaiaoe/i? ca’ycee, ye? ci?iththoue ia?aa?a oeeo
caoai?thaaiue, ui oneeaaeith? oa?ai?th ? i?ecaiaeeoue aei o?ii?/iiai
ia?aa?ao caoai?thaaiiy. O iaoiaaiac? ae?aceiai? oai?iae aaeeea cia/aiiy
ia? ii?ooaiiy iioi?ii-aaaeoaoi?ii? ooieoe?? aeaaiaaeoeyoeiaei? eeoee ?
oeoiea, a oaeiae ii?ooaiiy aeia/iaea?aeieo oeyo?a, i?aeoeoieiai? caeice
? ia/?iee. Iiaiioe?iia ae?aaiinoeea niieo/aieo o?aaeaiue oeoiea ?
aeaaiaaeoeyoeiaei? eeoee aeicaiey? cia/ii iie?aueoe ye?noue e?eoaaiiy,
aeiaeoeny ?oaoethaaiiy ae?acee o iaeei?ioo? oa?i?ie, cia/ii ca?eueoeoe
ia??iae ?ai?n?? caoai?thaaiiy (Aaaae I.ss., Oaaeaaiei A.Ae., 1997,
Chopra S., Sugarman D., 1990).

I?ia?aeieie caniaaie ae?aaiinoeee ae?aceiai? oai?iae oa noiooi?o
ooieoe?iiaeueieo ii?ooaiue oeoieiai-eeoeiaiai o?aeoo ?:
o?a?ino?aaioiaeiaano?iaeoiaeaiineii?y c a?iin??th, ?I–iao??y,
?aioaaiieia?/i? iaoiaee, aano?iaeoiaeaiie?iac?ia?ao?y, iaiiiao??y,
o?aeoe?eia o?iiaoe/ia aeoiaeaiaeueia ciiaeoaaiiy (A?eai?ueaa I.ss.,
1998, *a?iia?iaue A.I., 1998, oa ?i.).

Aeine?aeaeaiiy iioi?eee ? oeoieiai? nae?aoe?? o oai?eo ia ae?aceiao
oai?iao ia? aaeeea cia/aiiy ia no?eueee aeey ae?aaiinoeee caoai?thaaiiy,
ne?eueee aeey aeyaeaiiy ooieoe?iiaeueieo ii?ooaiue ae?yeueiino? oeoiea,
coiiaeaieo ?iceaaeii iae?iaoii?aeueiiai ?aaoethaaiiy ? no?oe-oo?ieie
ci?iaie caeicenoiai aia?aoo.

A e?oa?aoo?? ie ia cono??ee ?ia?o ii canoinoaaiith niiniao aeiaiaiai
iii?oi?eiao, iniiaieo ?ioaa?aeueieo iieaciee?a ae?yeueiino? oeoiea ?
aeaaiaaeoeyoeiaei? eeoee o oai?eo ae?aceiaith oai?iaith a i?aeo?aaiee
ia??iae ? ia??iae ii?iaeueiiai o?aaeaiiy ca?aeii c oacaie iioi?eee
aeaaia-aeoeyoeiaei? eeoee. Niin?a aeiaiaiai iii?oi?eiao ?I, iioi?eee ?
oeneo oeoiea ? aeaaiaaeoeyoeiaei? eeoee a ii?aeiaii? c iie?iao???th
aeicaieyoue io?eiaoe iaea?eueo a??ia?aeio ?ioi?iaoe?th i?i
ooieoe?iiaeueiee noai ? oacio ?iaioo aeaaiaaeoeyoeiaei? eeoee, aea/eoe
?iaioo ?? ? oeoiea o a?ae-iia?aeiino? c oacaie iioi?eee o oai?eo ia
ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?eia
?iaioa aeeiiaia ca?aeii iaoeiai? oaiaoeee oa ieaio iaoeiai-aeine?aeieo
?ia?o eaoaae?e aano?iaioa?ieia?? Caii??cueeiai ?inoeoooo oaeineiiaeaiiy
e?ea??a IIC Oe?a?ie (? aea?ae?a?no?aoe?? 0195U029076).

Iaoa oa caaaeaiiy aeine?aeaeaiiy. Iaoith i?iaaaeaieo aeine?aeaeaiue aoei
aaeineiiaeaiiy ae?aaiinoeee ? e?eoaaiiy oai?eo ia ae?aceiao oai?iao
aeaaiaaeoeyoeiaei? eeoee oeyoii oa?iaeieia?/ii? ei?aeoe?? oacieo
aano?iaeoiaeaiaeueieo aeene?iac?e oa ii?ooaiue aeenoaciiai oeoieiaiai
eeneioiooai?aiiy.

Aeey aeinyaiaiiy iaoe aoee iinoaaeai? oae? caaaeaiiy:

1. Neiino?othaaoe ciiae aeey aeiaiaiai aiaoeaoi?iiai ? noaoe?iia?iiai
iii?oi?eiao oaciiai aioo??oiueiii?iaeieiiiai oeneo, oacii? iioi?eee ?
oaciiai ?I aano?iaeoiaeaiaeueii? ciie.

2. ?ic?iaeoe aeiaiao aiaoeaoi?io ? noaoe?iia?io ea?oo ?a?no?aoe??
oaciiai aioo??oiueiii?iaeieiiiai oeneo, oacii? iioi?eee ? oaciiai ?I
oeoiea ? aeaaiaaeoeyoeiaei? eeoee.

3. Ooi/ieoe cia/ei?noue ia?aiao??a (aioo??oiueiii?iaeieiiiai oeneo, ?I)
aano?iaeoiaeaiaeueii? ciie, io?eiaieo o oai?eo oa caei?iaeo in?a, ca
aeiiiiiaith niaoe?aeueii neiino?oeiaaiiai ciiaeo ? aeae?eeoe c ieo
iaea?eueo ?ioi?iaoeai?.

4. Aea/eoe ca’ycie aeenoacii? aano?iaeoiaeaiaeueii? iioi?eee c ??aiai
aeenoaciiai ?I oeoiea.

5. Aaeineiiaeeoe caniae oanooaaiiy i?e noae?iaaaeueiiio i?eeii? I2–
aeieaoi??a, aeieaoi??a i?ioiiii? iiiie oa i?ie?iaoee?a o oai?eo ia
ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee.

6. Aea/eoe aieea ?ai?oeaeeio, oaiioeaeeio ? iiai?acieo ia
aano?iaeoiaeaiaeuei? aeene?iac??, aecia/eoe ?oith aoaeoeai?noue aeey
ei?aeoe?? aeenoaciiai oeneo o oai?eo ia ae?aceiao oai?iao
aeaaiaaeoeyoeiaei? eeoee.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a. Aia?oa i?iaaaeaia oe?iea
e?euee?nia ii??aiyeueia aeine?aeaeaiiy caeaaeiino? ee?i?/ieo neiae?ii?a
a?ae oa?aeoa?o aano?iaeoiaeaiaeueieo aeene?iac?e. ?ic?iaeaiee ciiae aeey
aeiaiaiai aai aaaaoiaiaeeiiiai iii?oi?eiao aioo??oiueiii?iaeieiiiai
oeneo, oacii? iioi?eee ? ?I aano?iaeoiaeaiaeueii? ciie ? ?ic?iaeaia
ea?oa ?a?no?aoe?? io?eiaieo ?acoeueoao?a. Aia?oa cai?iiiiiaaiee
noae?iaaaeueiee oeyo oaaaeaiiy eeneioiaeieoth/eo i?aia?ao?a ?
i?ie?iaoee?a ye aeni?an–iaoiae ioe?iee ?oiuei? aoaeoeaiino?.
Cai?iiiiiaai? iaa?oioiaai? i?eioeeie aeeoa?aioe?eiaaiiai e?eoaaiiy
aano?iaeoiaeaiaeueieo aeene?iac?e c o?aooaaiiyi aeenoacii?
aano?iaeoiaeaiaeueii? iioi?eee ? aeenoaciiai ?I oeoiea.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a. Neiino?oeiaaiee ciiae aeey
aiaoeaoi?iiai aaaaoiaiaeeiiiai iii?oi?eiao aioo??oiueiii?iaeieiiiai
oeneo, oacii? iioi?eee ? ?I aano?iaeoiaeaiaeueii? ciie ? ?ic?iaeaia
ea?oa ?a?no?aoe?? io?eiaieo ?acoeueoao?a — aeicaieythoue eiiieaenii
ioe?ieoe ooieoe?iiaeueiee noai oeoiea ? aeaaiaaeoeyoeiaei? eeoee a
aoaeue-yeee /an aeiae. Ioe?iea aoaeoeaiino? aeieaoi??a oeoieiaiai
eeneioiooai?aiiy c aeiiiiiaith ?o noae?iaaaeueiiai i?eeiio aeicaiey? ia
i?ioyc? 90 oaeeei i?ae?a?aoe ?acia? ? eo?nia? aeice i?aia?ao?a, aieeaaoe
ia ??aaiue ?I oeoiea, ui aeicaiey? ?iaeea?aeoae?coaaoe i?ecia/aiiy
i?aia?ao?a. Noi?ioeueiaai? iniiai? i?eioeeie aeeoa?aioe?eiaaiiai
canoinoaaiiy oa?iaeieia?/ieo cania?a i?e oacieo aeene?iac?yo
aano?iaeoiaeaiaeueii? ciie o oai?eo ia ae?aceiao oai?iao
aeaaiaaeoeyoeiaei? eeoee.

?acoeueoaoe ?iaioe ai?iaaaeaeai? a i?aeoe/io ioi?iio caei?ia’y o
a?aeae?eaiiyo aano?iaioa?ieia?? i?nueeeo e?ea?aiue 6-? oa 9-?, IN* ?7,
aeei?enoiaothoueny a iaa/aeueiiio i?ioean? i?e aea/aii? oaie “Ae?aceiaa
oai?iaa”, “Aeene?iac?? oeoiea ? aeaaiaaeoeyoeiaei? eeoee” ia eaoaae??
oa?ai?? 2, aano?iaioa?ieia?? Caii??cueeiai ?inoeoooo oaeineiiaeaiiy
e?ea??a, Oe?a?inueeiio IAe? aano?iaioa?ieia??.

Iniaenoee aianie caeiaoaa/a. Caeiaoaa/ai cae?eniaii ?ic?iaeo iniiaieo
oai?aoe/ieo oa i?aeoe/ieo aeine?aeaeaiue, aea?? iai?yieo ? iaoiae?a
ianoaaeaiiy, a oaeiae oi?ioethaaiiy iaoe oa ocaiaeaeaiiy caaaeaiue aeey
?? aeinyaiaiiy. Naiino?eii i?iaaaeaii iniiaiee ianya ee?i?/ieo,
?ino?o-iaioaeueieo ? eaai?aoi?ieo aeine?aeaeaiue, ocaaaeueiaii
?acoeueoaoe noaoenoe/ii? ia?iaee oa i?iaaaeaii aiae?c io?eiaieo
?acoeueoao?a. Iniaenoi noi?ioeueiaai? aeniiaee ?iaioe, ?ic?iaeai?
i?aeoe/i? ?aeiiaiaeaoe?? ? caaacia/aii ?o ai?iaaaeaeaiiy a iaaee/io
i?aeoeeo oa a?aeia?aaeaiiy a iioae?eiaaieo i?aoeyo.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Aeena?oaoe?eia ?iaioa ai?iaiaaia
ia ni?eueiiio can?aeaii? ni?a?ia?oiee?a eaoaae?e aano?iaioa?ieia??,
n?iaeii? iaaeeoeeie oa oa?ai??-II Caii??cueeiai aea?aeaaiiai ?inoeoooo
oaeineiiaeaiiy e?ea??a.

Iniiai? iieiaeaiiy ? ?acoeueoaoe aeena?oaoe?eii? ?iaioe aeeeaaeai? ia
ca?oieo iaoeiaeo eiioa?aioe?yo Caii??cueeiai aea?aeaaiiai ?inoeoooo
oaeineiiaeaiiy e?ea??a o 1995, 1996, 1997, 1998 ?ieao; ia 2-io, 3-io
?in?enueeiio aano?iaioa?ieia?/iiio oeaei? o i. Iineaa (1996, 1997); ia
2-io, 3-io Oe?a?inueeiio oeaei? aano?iaioa?ieia?a o i. Aei?i?iiao?ianuee
(1998, 1999), ia iaoeiai-i?aeoe/i?e eiioa?aioe?? “?aaaeeeoaoeey aieueiuo
n aano?iyioa?ieiae/aneie iaoieiaeae” a 1996 ?ioe? o i. *a?i?aoe?, ia
eiioa?aioe?? iieiaeeo a/aieo Caii??cueeiai aea?aeaaiiai iaaee/iiai
oi?-aa?neoaoo ? Caii??cueeiai aea?aeaaiiai ?inoeoooo oaeineiiaeaiiy
e?ea??a a aa?aci? 1997 ?ieo.

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 18 iaoeiaeo i?aoeue oa
oac (6 – o aeo?iaeao oa ca??eao ca ia?ae?eii AAE Oe?a?ie; iaea?aeaiee 1
iaoaio ia aeiao?ae oa 2 iina?ae/aiiy i?i ?aoe?iiae?caoi?nueeo
i?iiiceoe?th).

Ianya ? no?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 168-e
noi??ieao iaoeiiieniiai oaenoo, neeaaea?oueny c anooio, 4 ?icae?e?a
aeanieo aeine?aeaeaiue, aiae?co ? ocaaaeueiaiiy ?acoeueoao?a
aeine?aeaeaiiy, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e oa nieneo
aeei?enoaieo aeaea?ae. Aeena?oaoe?y ?ethno?iaaia 9 i?e?ioioia?ao?yie, 7
iaethieaie oa 15 oaaeeoeyie, ye? caeiathoue 25 noi??iie. A?ae?ia?ao?/iee
iieaae/ee i?noeoue 253 aeaea?aea, c ieo 145 ee?eeeoeath oa 108 eaoeiith.

INIIAIA *ANOEIA

Ee?i?/ia oa?aeoa?enoeea oai?eo oa iaoiaee aeine?aeaeaiiy.

Aeey aeinyaiaiiy iinoaaeaii? iaoe i?iaaaeaia iiaeeaeaia
ee?i?ei-?ino?oiaioaeueia ianoaaeaiiy 135-e oai?eo ae?aceiaith oai?iaith
aeaaiaaeoeyoeiaei? eeoee. Aeey c’ynoaaiiy ii?iaeueieo iieaciee?a
aaee/ei, ui aea/athoueny, aoei ianoaaeaii 15 i?aeoe/ii caei?iaeo in?a
iaio noaoae o a?oe? a?ae 18-e aei 55-e ?ie?a.

Aano?iaeoiaeaiaeuei? ooieoe?? aecia/aeeny niiniaii iie?iao??? i?ioani?a
TH.? ?aoao?eiaa (aeiao?ae ? 4231513/14/042931) c ?a?no?aoe??th
iaea?aeaii? ?ioi?iaoe?? a?coaeueii ia ae?ai? iii?oi?o, a?ao?/ii ia
iaia?ia?e nioc? iie?a?aoa «Naetho». Aeiaiaee iii?oi?eia ?I, oeneo ?
iioi?eee oaeiae i?iaiaeeany ca aeiiiiiaith iaoiaeee ? i?eeaaeo TH.?.
?aoao?eiaa. ?a?no?aoe?y iaea?aeaii? ?ioi?iaoe?? i?iaiaeeeany a?coaeueii.
Aeey aiaoeaoi?ieo oai?eo aoea ?ic?iaeaia ea?oa ?a?no?aoe?? aiaeeiiiai
aai aeiaiaiai iii?oi?oaaiiy io?eiaieo ?acoeueoao?a.

Aeine?aeaeaiiy cae?enithaaeiny oaeei /eiii: iaoe??ioo a?aioe?, iaoua
aaiaeeany ciiae a aeaaiaaeoeyoeiaeo eeoeo. Eiio?ieue eieae?caoe?? ieeae
ciiaeo i?iaiaeeany ?aioaaiieia?/ii, niiniaii “oeiieo”, ii eieuei?o
io?eiaiiai nae?aoo, ii oa?aeoa?o a?ao?/ii? e?eai?, iaea?aeaii? ia nioc?
naiiienoey. Ia?aae aeine?aeaeaiiyi ciiae c ?I-iao?e/ieie aeao/eeaie
eae?a?oaaany ii noaiaea?oiei aooa?iei ?ic/eiai ?c cacaeaeaa?aeue
a?aeiiei ?I (AINO 8-135-74); iaea?aeaiee i?e oeueiio eae?a?oaaeueiee
neaiae caienoaaany a?ao?/ii.

Canoinoaaiiy aeaiiai ciiaeo aeicaiey? ca 3-5 aiaeei aeine?aeaeaiiy
io?eiaoe oaeo ?ioi?iaoe?th:

1. Oeie no?aaioiaeiaano?iaeoiaeaiie?iac?e.

2. Oeie no?aaioiaeiaano?i?iaeoiaeaiioii?e.

3. Aea/eoe i?aeo?aaio ? o?aaio iioi?eeo ? aioo??oiueiii?iaeieiiee oene.

4. Aea/eoe eeneioiooai?thth/o ooieoe?th oeoiea (aacaeueio ?
noeioeueiaaio).

5. Oanooaaoe aeoiaeaiiaano?aeueiee oa aano?iaeoiaeaiaeueiee ?aoethene.

6. I?iaiaeeoe oa?iaeieia?/i? i?iae.

I?ney cae?i/aiiy iie?iao??? i?iaiaeeany aeiaiaee iii?oi?eia ?I, oeneo ?
iioi?eee oeoiea ? aeaaiaaeoeyoeiaei? eeoee. I?eeaae, ia yeee aoa
iaea?aeaiee iaoaio (? 22852 A), neeaaea?oueny c ciiaeo, ui yaey? niaith
o?oaeo c ooi?iieanoo, ia ye?e ?ici?uai? o?e ia?e aeaeo?iae?a,
i?ecia/aieo aeey aei???a eeneioiino? na?aaeiaeua (?I) ? ?a?no?aoe?? oac
i?aeo?aaii? iioi?eee.

I?eeaae aeey aeine?aeaeaiiy oeoieiai-eeoeiaiai o?aeoo ia? oae? aaaeeea?
iniaeeaino?: c? noaie aeeeth/ai? aeaiaioe aeeaeaiiy – aeei?enoiao?oueny
??cieoey iioaioe?ae?a, ui ooai?th?oueny o aioo??oiueiii?iaeieiieo
?ic/eiao, ui aeicaieeei cia/ii ca?eueoeoe oi/i?noue aeine?aeaeaiue. Ca
?aoo-iie aeei?enoaiiy iiaeo iaoa??ae?a a i?ia?aeieeao ? aeaeo?iaeao,
ae?aiao? ciiaea aoa ciaioaiee a 3 ?ace ? ia ia?aaeuo? 5 ii, ui aia?oa
aeicaiey? i?iaiaeeoe o?eaaeee, aeiaiaee iii?oi?eia iniiaieo iieaciee?a
oeoieiai-eeoeiaiai o?aeoo a oiiaao, iaea?eueo aeecueeeo aei
o?c?ieia?/ieo.

Aeine?aeaeaiiy o?eaa? ia i?ioyc? 1 aeiae. ?acoeueoaoe ianoaaeaiiy, ye?
ci?ia? nai iaoe??io, caiinyoueny a “Ea?oo aeiaiaiai aiaoeaoi?iiai aai
noaoe?iia?iiai aaaaoiaiaeeiiiai iii?oi?eiao aioo??oiueiii?iaeieiiiai
oeneo, iioi?eee oa ?I aeaaiaaeoeyoeiaei? eeoee ? oeoiea”.

I?ae /an aeine?aeaeaiiy canoiniaoaaeenue i?aia?aoe I2-aeieoth/i? ae?? —
?ai?oeaeei («?ai?nai») ii 150 aai 300 ia, Oaiioeaeei («Aano?ineaeei»,
«Iaaioai», «Eaaiaoae») ii 40 ia ? aeieaoi? i?ioiiieo ianin?a — Iiai?acie
(«Iiac») ii 20 aai 40 ia, i?ie?iaoee – “Iio?e?oi” ii 10ia. I?aia?aoe
canoiniaoaaeenue noae?iaaaeueii a ii?ioeo ? ia?i?aeueii. On?i oai?ei ia
ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee i?ecia/aeenue no/ani? noaie
aio?oae?eiaaeoa?ii? oa?i?? (Megraud F, 1997).

Noaoenoe/io ia?iaeo aenia?eiaioaeueiiai iaoa??aeo i?iaiaeeee ca
aeiiiiiaith iaoiae?a aa??aoe?eii? noaoenoeee (i?ia?aiiee iaeao
“Statgraph”) ia eiii’thoa?? oeio IBM PC AT.

?ACOEUeOAOE AeINE?AeAEAIIss, ?O AIAE?C OA IAAIAI?AIIss

Ee?i?/i? niinoa?aaeaiiy iieacaee, ui ae?aceiaa oai?iaa c ii?iie?iac??th
aeaaiaaeoeyoeiaei? eeoee oa?aeoa?eco?oueny iii??iei aieth/ei neiae?iiii
? noi?iaiaeaeo?oueny iii??ieie ii?ooaiiyie iioi?ii-aaaeoaoi?ii? ooieoe??
oeoiea ? aeaaiaaeoeyoeiaei? eeoee.

?ooia? ii?ooaiiy aa?oi?o a?aeae?e?a oeoieiai-eeoeiaiai o?aeoo i?e
a?ia?iioi?i?e aeene?iac?? aeaaiaaeoeyoeiaei? eeoee oa?aeoa?ecothoueny
nei?i/aiiyi oace niieith aae aei ?? cieeiaiiy, iiaeiaaeaiiyi oace
ia?aaoey?ieo nei?i/aiue ? oace ?eoi?/ieo nei?i/aiue c ia?aeaeueiei
c?inoai-iyi aeeiai?/ieo, neeiaeo (aiie?ooaea nei?i/aiue) ? noaoe/ieo
(aioo??oiueiii?iaeieiiee oene) oa?aeoa?enoee iioi?eee. Ee?i?ea
ae?aceiai? oai?iae c noiooiueith a?ia?iioi?iith aeene?iac??th
aeaaiaaeoeyoeiaei? eeoee aeyaey?oueny a?eueo neeueiei aieth/ei ?
aeeniaioe/iei neiae?iiii, i?ae c noiooiuei? ii?iie?iac??th.

A ee?i?/i?e ea?oei? ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee c
noiooiueith a?iiiioi?iith aeene?iac??th aeaaiaaeoeyoeiaei? eeoee
ia?aaaaea? “neiae?ii i?aaiai i?ae?aaa?’y”, iniaeeai o ae?iie. A ca’yceo
c oeei ia?aeiia ae?aaiinoeea ae?aceiai? oai?iae /anoi oneeaaeiaia, ?
oae? oai?? aeiaai ? ia?ii e?eothoueny c i?eaiaeo o?ii?/ieo
oieaoeenoeo?a, aeene?iac??, ui iineeth? iniiaiee iaoieia?/iee i?ioean.
Ie aaaaea?ii, ui o?ii?/i? caoai?thaaiiy aeaaiaaeoeyoeiaei? eeoee – ye
ooieoe?iiaeueii?, oae ? caiaeueii? i?e?iaee – ? aoi?eiieie. I?e
ae?aaiinoeoe? oeeo caoai?thaaiue iaiao?aeii, ia?aaeon?i, aeeeth/eoe
ia?aeii? caoai?thaaiiy i?aai?a aa?oi?o a?aeae?e?a oeoieiai-eeoeiaiai
o?aeoo, oeoiea ? aeaaiaaeoeyoeiaei? eeoee.

I?e aeine?aeaeaii? aca?iica’yceo ?io?aaano?iaeoiaeaiaeueiiai oeneo ?
iioi?eee aoee io?eiai? oae? ?acoeueoaoe: o 101-ai (76%) c 135-e oai?eo
ae?aceiaith oai?iaith aeaaiaaeoeyoeiaei? eeoee ?a?no?oaaeany aiie?ooaea
oeoieiaeo nei?i/aiue iiiaae 27 ii ?o.no. Aioo??oiueiii?iaeieiiee oene
oeoiea o oaco niieith neeaa 14,6 0,4 ii ?o.no., a o oaco ?iaioe — 10,0
0,5 ii ?o. no. I?aeoaciee a?aae??io aioo??oiueiii?iaeieiiiai oeneo
aei??aithaaa 4,6 0,1 ii ?o. no. I?aeaeuaiee aacaeueiee oene ?
aiie?ooaea nei?i/aiue ? a?aeaeooyi i?aeaeuaiiai oiiono i’yciai? no?iee
oeoiea. ?io?aaeo-iaeaiaeueiee oene i?e a?ia?iioi?eoe? aeaaiaaeoeyoeiaei?
eeoee o oaco niieith neeaa 17,8 0,2 ii ?o. no., a o oaco ?iaioe — 14,0
0,3 ii ?o.no., i?e oeueiio i?aeoaciee a?aae??io aioo??oiueiii?iaeieiiiai
oeneo ca?eueoeany aei 3,8 0,1 ii ?o. no. (a?aei?iiino? c eiio?ieueiith
a?oiith noaoenoe/ii a??ia?aei?, (?< 0,05)). O oai?eo ae?aceiaith oai?iaith aeaaiaaeoeyoeiaei? eeoee c a?ia?iioi?eeith oeoiea i?aeaeuaiiy oeneo a oeoieo aoei ae?aaeaia a?eueoith i??ith o oaco niieith (a ii??aiyii? c eiio?ieueiith a?oiith a?aeiia?aeii 14,6 0,4 ii ?o. no. ? 12,5 0,2 ii ?o. no., i?ae o oaco ?iaioe (a?aeiia?aeii 9,0 0,5 ? 10,0 0,5 ii ?o. no.) Oea na?ae/eoue i?i i?aeaeuaiiy ?io?aaano?aeueiiai oeneo a?eueoa o oaco niieith, i?ae o oaco ?iaioe o oai?eo ae?aceiaith oai?iaith aeaaiaaeoeyoeiaei? eeoee, ui iia’ycaii c a?eueoith oii?/iith iai?oaith i’yciai? no?iee, yea iaa?oue o oaco ?iaioe ia cieaeo?oueny aei ??aiy iai?oae i’yciai? no?iee oeoiea o caei?iaeo in?a. Aiaeia?/i? aca?iica'ycee a?ia?iioi?eee ? aioo??oiueiii?iaeieiiiai oaciiai oeneo aeaaiaaeoeyoeiaei? eeoee aeyaeai? o 90-a c 135-e oai?eo ae?aceiaith oai?iaith i?e ii??aiyii? c? caei?iaeie; ?io?aaeoiaeaiaeueiee oene o oaco niieith neeaa a?aeiia?aeii 17,8 0,2 ii ?o. no. i?ioe 14,5 0,5 (?<0,05) o caei?iaeo. Oaae naia niinoa??aa?oueny ? a aeaaiaaeoeyoeiae?e eeooe? i?e ?? a?ia?iioi?i?e aeene?iac?? – a?aecia/a?oueny i?aeaeuaiiy oeneo a ii??aiyii? c? caei?iaeie, i?e/iio o oaco niieith a?eueoith i??ith, i?ae o oaco ?iaioe. O 20-e c 135-e oai?eo ae?aceiaith oai?iaith aeaaiaaeoeyoeiaei? eeoee niinoa??aaeany ii?iiiioi?eea oeoiea ? o 18-e – aeaaiaaeoeyoeiaei? eeoee. Aioo??oiueiii?iaeieiiee oene a oeoieo ? aeaaiaaeoeyoeiae?e eeooe? a oeeo a?oiao oai?eo iaa oaiaeaioe?th aei i?aeaeuaiiy ye o oaco nii-eith, oae ? o oaco ?iaioe. Oene a oeoieo neeaa o oaco niieith 13,8 0,3 ii ?o. no., o oaco ?iaioe - 9,7 0,2 ii ?o. no.; a aeaaiaaeoeyoeiae?e eeooe? - o oaco niieith 16,3 0,3 ii ?o. no., o oaco ?iaioe - 13,9 0,4 ii ?o. no. Iao? aeine?aeaeaiiy i?e ae?aceia?e oai?ia? aeyaeee cieaeaio aiie?ooaeo nei?i/aiiy oeoiea o 8-e oai?eo (9,4 1,0 ii ?o. no.) ? aeaaiaaeoeyoeiaei? eeoee o 7-e oai?eo (8,0 0,9 ii ?o. no.). Oiio o oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee iiaea aooe a?iiaano?iaeoiaeaiie?iac?y, i?e oeueiio oene oeoiea ? aeaaiaaeoeyoeiaei? eeoee ia? oaiaeaioe?th aei i?ae-aeuaiiy. O 115-e (85%) oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee niinoa??aaeiny i?aeaeuaiiy eeneioiooai?aiiy oeoiea. Oeoieiaa eeneioiooai?aiiy oai?eo c ii?iie?iac??th oeoiea ? aeaaiaaeoeyoeiaei? eeoee aoei ii?iaeueiei. Eeneioiooai?aiiy cia/ii ci?ithaaeiny i?e iiya? o oai?eo aeene?iac?? oeoiea ? aeaaiaaeoeyoeiaei? eeoee. A?ia?iioi?ia aeene?iac?y o oai?eo ae?aceiaith oai?iaith oa?aeoa?ecoaaeany aeii?ioaaiiyi cieaeaiiai ?I – a?ia?iioi?eea oeoiea c iecueeei ?I o 104-o oai?eo, a?ia?iioi?eea aeaaiaaeoeyoeiaei? eeoee a?aeiia?aeii - o 101-ai. A?ia?-iioi?ia aeene?iac?y cono??/aeany a iiiaeeiieeo aeiaaeeao i?e ii?iaeueiiio ?I a aacaeueio ? noeioeueiaaio oaco eeneioiooai?aiiy (aeey oeoiea ? aeaaiaaeoeyoeiaei? eeoee a?aeiia?aeii o 3-o c 20-e ? aeaio c 10-e oai?eo; o aeaio c 20-e ? o iaeiiai c 10-e oai?eo ia ae?aceiao oai?iao). O an?o oai?eo c a?iie?iaoe/iith aano?iaeoiaeaiaeueiith aeene?iac??th c iecueeei ?I (4-e iniae) iaie aeyaeaia a?ia?aano?iaeoiaeaiioii?y ye o oaco niieith, oae ? o oaco ?iaioe, i?e oeueiio i?aeoaciee a?aae??io oeneo a eiaeiiio i?aai? aoa ia iaioa 2 ii. ?o. no. A?aoiaoth/e ni?yioaaiiy iaoi? ?iaioe, aoei iinoaaeaia caaaeaiiy aeiaanoe aoaeoeai?noue oiai aai ?ioiai i?aia?aoo aeey cieaeaiiy eeneioiino? o oai?eo ae?aceiaith oai?iaith aeaaiaaeoeyoeiaei? eeoee ? ii??aiyoe ?? c ?acoeueoaoaie, io?eiaieie o caei?iaeo in?a. I?aea?? i?aia?ao?a i?iaiaeeany a?ae a?eueo neaaeeo aei a?eueo neeueieo i?aia?ao?a. A?aoiaoaaeeny ?aeiiaiaeaoe?? aaoi??a (A?eai?ue?a I.ss., A?eoeaiei ?.?., 1995) ii na?aaeiueioa?aiaaoe/iei ? aeiaiaei aeicai i?aia?ao?a, ui aeine?aeaeoaaeenue. Aeine?aeaeaiiy i?iaiaeeeeny a oiiaao, iaea?eueo aeecueeeo aei o?c?ieia?/ieo: iaoe??io a?a onoaeaiee niin?a aeeooy - cae/aeii oa?/oaaany, i?eeiaa i?ecia/ai? i?aia?aoe, ?aaoey?ii caiinea io?eiai? ?acoeueoaoe a ea?oo ?a?no?aoe?? iieaciee?a. Aoa canoiniaaiee ?ic?iaeaiee iaie niin?a noae?iaaaeueiiai oaaaeaiiy i?aia?ao?a. A iniiao iieeaaeaiee oie oaeo, ui i?e aeaiiio niinia? aoaea a?aenooi?e aoaeo iaeo?ae?caoe?? I2-aeieoth/iai i?aia?aoo ia/?ieith, oiaoi i?aia?ao ii/eia? aoaeoeaii ae?yoe iaaaaaoi ?ai?oa. Aoaeue-yeee aeieaoi? i?ioiiii? iiiie aeey oiai, uia i?iyaeoe naith ae?th ia ia???oaeueio ee?oeio, iiaeiai i?ieoe oaeee oeyo: i?eeii per os oeoiie eeoe?aiee aniieooaaiiy iaoaaie?ci o ia/?ioe? caaaeueiee e?iaiia?a ia???oaeueia ee?oeia. Oaeei /eiii, cai?iiiiiaaiee iaie oeyo noae?iaaaeueiiai aaaaeaiiy i?aia?ao?a aeeeth/a? ae?oaee, o?ao?e oa i’yoee aoaie oeueiai oeyoo. O caei?iaeo in?a iaea?eueo o?eaaeee ia??iae ae?? aoa aeyaeaiee o iiai?acieo ? neeaa i?e ia?i?aeueiiio oaaaeaii? 695,0 9,5 oa., a i?e noae?iaaaeueiiio – 622,0 6,5 oa., i?e/iio eaoaioiee ia??iae i?e ia?i?aeueiiio oaaaeaii? neeaaeaa 151,5 6,0 oa., a i?e noae?iaaaeueiiio– 62,0 9,0 oa. I?e canoinoaaii? oaiioeaeeio aoee io?eiai? oae? ?acoeueoaoe: i?e ia?i?aeueiiio oaaaeaii? – 570,0 9,0 oa., a i?e noae?iaaaeueiiio - 542,0 6,5 oa., eaoaioiee ia??iae i?e ia?i?aeueiiio oaaaeaii? neeaaeaa 137,04,5 oa., i?e noae?iaaaeueiiio – 52,5 8,5 oa. I?e aeei?enoaii? ?ai?oeaeeio – i?e ia?i?aeueiiio oaaaeaii? 296,5 8,5 oa., a i?e noae?iaaaeueiiio – 293,5 6,0 oa., i?e/iio eaoaioiee ia??iae i?e ia?i?aeueiiio oaaaeaii? neeaaeaa 135,5 7,5 oaeeei, a i?e noae?iaaaeueiiio – 34,5 3,0 oa. Aea/eaoe iaaaaeai? aeua aeai?, iiaeia i?eionoeoe, ui /an ae?? i?aia?ao?a, ui aea/athoueny, ??ciiiai?oiee: a?i iaea?eueoee o iiai?acieo ? iaeiaioee o ?ai?oeaeeio, i?e/iio oe? aeai? a??ia?aeii (?<0,05) ei?aeththoue ye i?e ia?i?aeueiiio, oae ? i?e noae?iaaaeueiiio oaaaeaii? i?aia?aoo. I?e noae?iaaaeueiiio oaaaeaii? /an ae?? i?aia?aoo aeaui iaioee, aea aoaeo ianoa? ?ai?oa. I?eaa?oa? oaaao oa, ui o oai?eo ia ae?aceo aeaaiaaeoeyoeiaei? eeoee o?eaaeee ia??iae ae?? aoa aeyaeaiee o iiai?acieo ? neeaa i?e ia?i?aeueiiio oaaaeaii? 637,5 10,0 oa., a i?e noae?iaaaeueiiio – 623,0 11,5 oa., i?e/iio eaoaioiee ia??iae i?e ia?i?aeueiiio oaaaeaii? neeaaeaa 161,0 2,5 oa., a i?e noae?iaaaeueiiio – 60,5 6,0 oa. (?<0,05). I?e canoinoaaii? oaiioeaeeio aoee io?eiai? oae? ?acoeueoaoe: i?e ia?i?aeueiiio oaaaeaii? ia??iae ae?? neeaa 463,0 4,5 oa., a i?e noae?iaaaeueiiio – 452,0 6,5 oa., eaoaioiee ia??iae i?e ia?i?aeueiiio oaaaeaii? neeaa 139,5 7,0 oa., i?e noae?iaaaeueiiio – 56,0 2,0 oa. (?<0,05). I?e aeei?enoaii? ?ai?oeaeeio i?e ia?i?aeueiiio oaaaeaii? /an ae?? – 296,0 8,5 oa., a i?e noae?iaaaeueiiio – 293,0 6,0 oa., i?e/iio eaoaioiee ia??iae i?e ia?i?aeueiiio oaaaeaii? neeaaeaa 134,5 4,5 oa., a i?e noae?iaaaeueiiio – 39,5 9,5 oa. (?<0,05). Aea/eaoe iaaaaeai? aeua aeai?, iiaeia c?iaeoe aeniiaie, ui, ye ? o caei?iaeo in?a, /an ae?? i?aia?ao?a, ui aea/athoueny, ??ciiiai?oiee: a?i iaea?eueoee o iiai?acieo ? iaeiaioee o ?ai?oeaeeio, i?e/iio oe? aeai? a??ia?aeii (?<0,05) ei?aeththoue ye i?e ia?i?aeueiiio, oae ? i?e noae?i-aaaeueiiio oaaaeaii? i?aia?aoo. Iaie aoei a?aecia/aii, ui ia an? i?aia?aoe iaeiaeiai aoaeoeai? - iaea?eueoa e?euee?noue oai?eo c ?acenoaioi?noth aei i?aia?aoo aoea i?e canoinoaaii? iiai?acieo ("Iiac") – 25% (?<0,05), iaeiaioa – i?e canoinoaaii? oaiioeaeeio – 12,5% (?<0,05). Ca?aeii c iaoeie aeaieie, ?acen-oaioi?noue iia'ycaia c iaaeinoaoiueith aeicith i?aia?aoo aai c iaaoaeoeai?noth aeaiiai i?aia?aoo aeey eiie?aoiiai oai?iai. C o?aooaaiiyi i?iaaaeaieo aeine?aeaeaiue c?iaeaia ni?iaa i?iaanoe e?eoaaiiy ??ciiiai?oieie i?aia?aoaie c iaoith ii?iae?caoe?? oacieo aano?iaeoiaeaiaeueieo aeene?iac?e. A ?iaio? aeei?enoiaoaaeenue iio?e?oi, iaioaaano?ei, iiai?acie, oaiioeaeei. Canoinoaaiiy oeeo i?aia?ao?a a?oioo?oueny ia iiia?aaei?o niinoa?aaeaiiyo, ye? iieacaee, ui icia/ai? i?aia?aoe iiaeooue aeyaeyoe aieea ia aiie?ooaeo nei?i/aiue ? o?eaae?noue oac iioi?eee. Ia ii/aoeo aeine?aeaeaiiy, c iaoith a?aei?aoethaaiiy iieacaiue aei eo?niaiai i?ecia/aiiy i?aia?ao?a aoee i?iaaaeai? aino?? oa?iaeieia?/i? i?iae. Aieea i?aia?ao?a ia iioi?eeo oeoiea ? aeaaiaaeoeyoeiaei? eeoee ioe?ithaaany ca ci?iith o?eaaeino? oac iioi?eee ? aiie?ooaee nei?i/aiue. O oai?eo ae?aceiaith oai?iaith i?ae ae??th iio?e?oio o?eaae?noue I oace ca?eueooaaeany i?e ii/aoeiai ciaioai?e o 4-o c 20-e oai?eo, i?e/iio aei ??aiy ii?iaeueii? o?eaaeino?. O 12-e c 20-e iaoe??io?a o?eaae?noue I oace ciaiooaaeany, o 4-o oai?eo c ii/aoeiai ii?iaeueiith o?eaae?noth I oaca ia ci?ithaaeany. O?eaae?noue II oace aano?iaeoiaeaiaeueii? iioi?eee ca?eueooaaeany o 12-e c 20-e ? ciaiooaaeany aei ii?ie o 4-o c 20-e oai?eo c ii/aoeiai ca?eueoaiith o?eaae?noth. Ii/aoeiai ii?iaeueia o?eaae?noue II oace o 4-o oai?eo i?ae ae??th iio?e?oio ia ci?ithaaeany. III oaca aano?iaeoiaeaiaeueii? iioi?eee ii/aoeiai ca?eueoaiith aoea o 13-e c 20-e oai?eo ae?aceiaith oai?iaith. I?ae aieeaii i?aia?aoo ?? o?eaae?noue ca?eueooaaeany o 10-e c 13-e ? ciaiooaaeany aei ??aiy ii?ie o 3-o c 13-e oai?eo c ii/aoeiai ca?eueoaiith o?eaae?noth, o aeaio oai?eo c a?oie c ii/aoeiai ciaioaiith o?eaae?noth III oaca ii?iae?coaaeany, o 5-e oai?eo ii/aoeiai ii?iaeueia o?eaae?noue ia ci?ithaaeany. Oaeei /eiii, i?e iaeii?aciaiio oaaaeaii? iio?e?oio oai?ei ae?aceiaith oai?iaith aeaaiaaeoeyoeiaei? eeoee o?eaae?noue ?iaioe oeoiea ? aeaaiaaeoeyoeiaei? eeoee /ano?oa ca?eueoo?oueny, a o?eaae?noue niieith /ano?oa ciaioo?oueny. I?ae aieeaii iio?e?oio aiie?ooaea nei?i/aiue ca?eueooaaeany o 13-e oai?eo (o 8-e i?e ii/aoeiai i?aeaeuai?e, o 3-o – c ii?iaeueiith, o aeaio - c? cieaeaiith), ia ci?ithaaeany o 4-o oai?eo (i?e ii/aoeiai ii?iaeuei?e o 3-o c 6-e ? ii/aoeiai cieaeai?e o iaeiiai c 4-o), ciaiooaaeany o 3-o oai?eo (i?e ii/aoeiai i?aeaeuai?e o aeaio c 10-e ? ii/aoeiai cieaeai?e o iaeiiai iaoe??ioa). I?aeaeuaiiy aiie?ooaee aei ii?ie aoei o aeaio c 4-io oai?eo c ii/aoeiai cieaeaiith aiie?ooaeith. I?ae aieeaii iaioaaano?eio ciaiooaaeany I oaca ii o?eaaeino? o 13-e c 20-e oai?eo; ca?eueooaaeany aei ii?ie o 3-o c 20-e oai?eo ae?aceiaith oai?iaith, o yeeo ii/aoeiaa o?eaae?noue aoea ciaioaiith; o 4-o oai?eo ii/aoeiai ii?iaeueia o?eaae?noue I oace ia ci?ithaaeany; II oaca aano?iaeoiaeaiaeueii? iioi?eee ca?eueooaaeany o 13-e c 20-e ? ii?iae?coaaeany (ca ?aooiie ciaioaiiy) o 3-o c 20-e oai?eo c ii/aoeiai ca?eueoaiith o?eaae?noth II oace, a a?oi? oai?eo (4-e iniae) ii/aoeiai ii?iaeueia o?eaae?noue ia ci?ithaaeany. III oaca aeoiaeaiaeueii? iioi?eee i?ae aieeaii iaioaaano?eio ca?eueooaaeany o 6-e c 13-e ? ciaiooaaeany aei ii?ie o 5-e c 13-e oai?eo c ii/aoeiai ca?eueoaiith o?eaae?noth, a a?oi? oai?eo (7 in?a) c ii/aoeiai ii?iaeueiith o?eaae?noth III oaca ciaiooaaeany o iaeiiai, o 4-o i?ae aieeaii iaioaaano?eio aiia ia ci?ithaaeany, a o aeaio oai?eo c ii/aoeiai ciaioaiith o?eaae?noth aiia ca?eueooaaeany. Iaioaaano?ei ca?eueooaaa aiie?ooaeo nei?i/aiue o 8-e oai?eo (o 6-e c 10-e c ii/aoeiai i?aeaeuaiith, o iaeiiai c 6-e - c ii?iaeueiith, o iaeiiai c 4-o - cieaeaiith); ia ci?ithaaa o 9-e oai?eo (o aeaio c 10-e c ii/aoeiai i?aeaeuaiith, o 4-o c 6-e - ii?iaeueiith o 3-o c 4-o – c? cieaeaiith); ciaiooaaa o 4-o oai?eo (o aeaio c 10-e c ii/aoeiai i?aeaeuaiith, o iaeiiai c 6-e – c ii?iaeueiith, o iaeiiai c 4-o - cieaeaiith). Oaeei /eiii, i?e iaeii?aciaiio oaaaeaii? iaioaaano?eio oai?ei ae?aceiaith oai?iaith /ano?oa ca?eueooaaeany o?eaae?noue oac ?iaioe (?<0,05), i?ae oac niieith oeoiea ? aeaaiaaeoeyoeiaei? eeoee (?<0,05). Aiie?ooaea nei?i/aiue /ano?oa ca?eueooaaeany. A on?o oai?eo iaioaaano?ei iiaeoethaaa III oaco aeoiaeaiaeueii? iioi?eee. C i?iaaaeaieo aeine?aeaeaiue aieeao ?aciaiai canoinoaaiiy iio?e?oio ? iaioaaano?eio ia o?eaae?noue oac aano?iaeoiaeaiaeueii? iioi?eee ? aiie?ooaeo nei?i/aiue neeaaea?oueny aeoiea i?i ?o ?aeaioe/io ae?th: II ? III oace ca?eueoothoueny, I oaca - ciaioo?oueny (a?aei?iiino? noaoenoe/ii a??ia?aei?, ?<0,05), aiie?ooaea nei?i/aiue a a?eueoino? aeiaaee?a (o 13-e c 20-e) ca?eueooaaeany, iniaeeai /anoi a?aecia/aeany o oai?eo c ii/aoeiai i?aeaeuaiith aiie?ooaeith oeoiea ? aeaaiaaeoeyoeiaei? eeoee. Ca?a ?acoeueoao?a aeine?aeaeaiiy oa?iaeieia?/ieo i?ia iio?e?oiii ? iaioaaano?eiii na?ae/eoue i?i iiae?aiee aieea, ia ca?eueoaiiy nei?i/oaaeueii? ooieoe?? oeoiea ? aeaaiaaeoeyoeiaei? eeoee. Ii?ooaiiy nei?i/oaaeueii? ooieoe?? oeoiea ni?eythoue aeen?eoi?? iioi?eee, ?iaioe ? a?aeii/eieo i'yco, a?eueo o?eaaeiio caeeneaiith aio?iaeoiaeaiaeueii? ciie ? iieiioe? aio?iaeoiaeaiaeueiiai aaeueia, c?eao eiiiainaoi?ii-aaeaioaoe?eieo iaoai?ci?a oeoiea ? aeaaiaaeoeyoeiaei? eeoee, ui iiaea i?ecaiaeeoe aei iiaeaeueoiai ?icaeoeo oeueoea?aoe?? ? a?aenooiino? iiceoeaiiai ee?i?/iiai aoaeoo. Oiio iiaeia aaaaeaoe iaaeioe?eueiei canoiniaoaaiiy iio?e?oio o oai?eo c ae?aceiaith oai?iaith aeey eo?niaiai e?eoaaiiy o ieo aano?iaeoiaeaiaeueieo a?ia?e?iac?e. I?ae ae??th oaiioeaeeio o?eaae?noue II oace ciaiooaaeany aei ii?ie o 12-e c 16-e ? ia ci?ithaaeany o 4-o c 16-e oai?eo c ii/aoeiai ca?eueoaiith o?eaae?noth, ii/aoeiai ii?iaeueia o?eaae?noue ia ci?ithaaeany (o 4-o c 4-o oai?eo); III oaca ciaiooaaeany aei ii?ie o 12-e c 16-e ? ia ci?ithaaeany o 4-o c 16-e oai?eo c ii/aoeiai ca?eueoaiith o?eaae?noth. Ii/aoeiai ii?iaeueia o?eaae?noue III oace i?ae aieeaii oaiioeaeeio ia ci?ithaaeany. O?eaae?noue I oace aeoiaeaiaeueii? iioi?eee ii?iae?coaaeany o 10-e c 13-e ? ia ci?ithaaeany o 3-o c 13-e oai?eo c ii/aoeiai ca?eueoaiith o?eaae?noth, ia ci?ithaaeany ii/aoeiai ii?iaeueia o?eaae?noue o 5-e c 5-e oai?eo, ca?eueooaaeany aei ii?ie o iaeiiai c aeaio ? ia ci?ithaaeany o iaeiiai c aeaio oai?eo c ii/aoeiai ciaioaiith o?eaae?noth. Oaiioeaeei o oai?eo ae?aceiaith oai?iaith o aeaio c 4-o cieaeoaaa ii/aoeiai i?aeaeuaio aiie?ooaeo aei ii?ie, ia ci?ithaaa o 10-e c 20-e (o 3-o c 10-e c ii/aoeiai i?aeaeuaiith, o 5-e c 6-e – c ii?iaeueiith, o aeaio c 4-o c? cieaeaiith aiie?ooaeith nei?i/aiue). I?ae ae??th iiai?acieo ? oaiioeaeeio o oai?eo ae?aceiaith oai?iaith o?eaae?noue I oace ca?eueooaaeany, II ? III oace - ciaiooaaeany aiie?ooaea nei?i/aiue cieaeoaaeany (?<0,05). ?acoeueoaoe aaaaoi?aciaeo oa?iaeieia?/ieo i?ia iiai?acieii ? oaiioeaeeiii na?ae/aoue i?i ?o ii?iae?coth/o ae?th ia o?eaae?noue oac iioi?eee ? aiie?ooaeo nei?i/aiue. Oiio iiai?acie ? oaiioeaeei canoiniaoaaee aeey eo?niaiai e?eoaaiiy oai?eo ia ae?aceiao oai?iao c aano?iaeoiaeaiaeueieie aeene?iac?yie. O oai?eo ae?aceiaith oai?iaith ci?ie aano?iaeoiaeaiaeueii? iioi?eee ii o?eaaeino? oac ? aiie?ooae? nei?i/aiue i?e aino??e oa?iaeieia?/i?e i?ia? iiai?acieii aoee aiaeia?/ieie ci?iai, io?eiaiei i?e aino??e oa?iaeieia?/i?e i?ia? oaiioeaeeiii. O oai?eo ae?aceiaith oai?iaith i?ney e?eoaaiiy iiai?acieii I oaca ca?eueoo?oueny aei ii?ie o 40-a c 48-e ? ia ci?ith?oueny o 3-o c 48-e oai?eo c ii/aoeiai ciaioaiith o?eaae?noth, ia ci?ithaaeany o 12-e c ii/aoeiai ii?iaeueiith o?eaae?noth. II aano?iaeoiaeaiaeueia oaca ciaiooaaeany aei ii?ie o 45-e c 48-e ? ia ci?ithaaeany o 3-o c 48-e oai?eo c ii/aoeiai ca?eueoaiith o?eaae?noth, o 12-e caeeoaeany ii?iaeueiith. III oaca ii o?eaaeino? ciaiooaaeany aei ii?ie o 36-e c 39-e oai?eo ? o 3-o caeeoeeany aac ci?i c ii/aoeiai ca?eueoaiith; ca?eueooaaeany aei ii?ie o 3-o c 6-e ? ia ci?ithaaeany o 3-o c 6-e oai?eo c ii/aoeiai ciaioaiith o?eaae?noth, caeeoaeany ii?iaeueiith o 16-e oai?eo. Aiie?ooaea nei?i/aiue ca?eueooaaeany aei ii?ie o 6-e c 12-e oai?eo c ii/aoeiai iecueeith, ia ci?ithaaeany o 40-a oai?eo (o 6-e c ii/aoeiai i?aeaeuaiith, o 18-e c ii/aoeiai ii?iaeueiith, o 6-e c ii/aoeiai cieaeaiith), ciaiooaaeany aei ii?ie o 24-o oai?eo. Ii?iae?caoe?y aiie?ooaee aano?i-aeoiaeaiaeueieo nei?i/aiue ianoaea o 50% oai?eo (?<0,05). O 18-e c 18-e oai?eo ?c ii/aoeiai ii?iaeueiith aiie?ooaea ia ci?ithaaeany. Oaeei /eiii, eo?niaa e?eoaaiiy eeneioiaeieoth/eie oa eeneioi?ia?aoth/eie i?aia?aoaie oai?eo ia ae?aceiao oai?iao /ano?oa aeyaey? ii?iae?coth/ee aieea ia o?eaae?noue I ? II oace. O 116-e (87%) oai?eo ii?iae?caoe?y o?eaaeino? I oace niinoa??aaeany ca ?aooiie ca?eueoaiiy ii/aoeiai ciaioaii? o?eaaeino? (?<0,01); II oace – ciaioaiiy ii/aoeiai ca?eueoaii? o?eaaeino? (?<0,01). Oe? i?aia?aoe ia aieeaathoue ia ii?iaeueio aiie?ooaeo aano?iaeoiaeaiaeueieo nei?i/aiue, o a?eueoino? oai?eo c i?aeaeuaiith aiie?ooaeith ae?thoue ii?iae?coth/e; i?e i?eeii? iiai?acieo (o 24-o c 30-e oai?eo) ? ii?iae?coth/e a iieiaei? aeiaaee?a c ii/aoeiai cieaeaiith aiie?ooaeith (o 6-e c 12-e oai?eo). AENIIAEE 1. ?ic?iaeai? eiiieaeniee ciiae aeey aioo??oiueiii?iaeieiiiai aeine?aeaeaiiy, i?eeaae aac ciai?oiueiai aeaea?aea aeeaeaiiy ? niin?a ?a?no?aoe?? aano?iaeoiaeaiaeueieo ooieoe?e ?c canoinoaaiiyi ea?oe aeiaiaiai aiaoeaoi?iiai noaoe?iia?iiai iii?oi?eiao oaciiai ?I, oaciiai oeneo ? oacii? iioi?eee oeoiea ? aeaaiaaeoeyoeiaei? eeoee aeicaieeee anoaiiaeoe, ui o caei?iaeo ethaeae ?io?aaano?iaeoiaeaiaeueiee oene a i?aeo?aaiee ia??iae ? aeaioaciei, caeaaeeoue a?ae aiie?ooaeieo, neeiaeo oa?aeoa?enoee ? a?ae oacii? aano?iaeoiaeaiaeueii? aeoeaiino?: a II ? III oaco a?i cieaeo?oueny, a a I oaco i?aeo?aaii? iioi?eee – i?aeaeuo?oueny. 2. Aecia/aii, ui o 85% ianoaaeaieo cono??/athoueny noiooi? oaci? aeene?iac?? oeoieo oa aeaaiaaeoeyoeiaei? eeoee. Oacia a?ia?iioi?ia aeene?iac?y cono??/a?oueny o 75%, a oacia a?iiiioi?ia aeene?iac?y – o 10% oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee. 3. Anoaiiaeaii, ui o oai?eo ae?aceiaith oai?iaith aeaaiaaeoeyoeiaei? eeoee a??ia?aeii /ano?oa a?aecia/a?oueny ii?ooaiiy iioi?eee aano?iaeoiaeaiaeueii? ciie c i?aeaeuaiiyi oiiiaiai aioo??oiueiii?iaeieiiiai oeneo a iaeaea? oace. 4. Niin?a oanooaaiiy ?ai?oeaeeio, oaiioeaeeio, iiai?acieo oa iio?e?oio oeyoii noae?iaaaeueiiai aaaaeaiiy oeeo i?aia?ao?a aeicaiey? c’ynoaaoe ?o aoaeoeai?noue, i?ae?a?aoe ?acia? ? eo?nia? aeice i?aia?ao?a, ui ?iaeea?aeoae?co? oa?ai?th ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee. 5. Cai?iiiiiaaiee noae?iaaaeueiee oeyo oaaaeaiiy ?ai?oeaeeio, oaiioeaeeio, iiai?acieo oa iio?e?oio o oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee i?enei?th? ianoaiiy ae?? oeeo i?aia?ao?a, ui aeicaiey? ca i?aoi?e-aea? aiaeeie i?ae?a?aoe ?o aaeaeaaoi? aeice. 6. I?e a?ia?oeeeeia?e ? a?ia?oaci?e aano?iaeoiaeaiaeuei?e iioi?eoe? a ii?aeiaii? c aenieei ?io?aaeoiaeaiaeueiei oeneii ? c iecueeeie cia/aiiyie aeenoaciiai ?I ei?iono ? aio?oio oeoiea aeioe?eueii canoinoaaiiy iiai?acieo aai oaiioeaeeio. 7. I?e a?iioeeeeia?e ? a?iioaci?e aano?iaeoiaeaiaeuei?e iioi?eoe?, ca a?aenooiino? III oace, a ii?aeiaii? c a?ii- aai a?ia??io?aaano?iaeoiaeaiaeueiei oeneii a iaeaea? oace aeioe?eueii i?ecia/aoe i?ie?iaoee iio?e?oi, a a ii?aeiaii? c iecueeei ?I oeoiea – c iiai?acieii aai oaiioeaeeiii. I?AEOE*I? ?AEIIAIAeAOe?? 1. Neiino?oeiaai? ciiae ? i?eeaae aeey aiaoeaoi?iiai aaaaoiaiaeeiiiai iii?oi?eiao ?I, iioi?eee oeoiea ? aeaaiaaeoeyoeiaei? eeoee iiaeooue aooe aeei?enoai? aeey ioe?iee ooieoe?iiaeueiiai noaio i?aai?a o?aaeaiiy a aoaeue-yeee /an aeiae a ?iaio? aano?iaioa?ieia?/ieo noaoe?iia??a ? iie?ee?i?e. 2. ?ic?iaeaiee niin?a oanooaaiiy ? i?aeai?o ?ai?oeaeeio, oaiioeaeeio, iiai?acieo oa iio?e?oio ca aeiiiiiaith noae?iaaaeueiiai i?eeiio aeicaiey? ia i?ioyc? 90 oaeeei i?ae?a?aoe ?acia? ? eo?nia? aeice i?aia?ao?a, aieeaaoe ia ??aaiue ?I oeoiea, ui aeicaiey? ?iaeea?aeoae?coaaoe oa?ai?th, ciaioeoe iaoa??aeuei? aeo?aoe ia e?eoaaiiy. 3. ?ic?iaeaia “Ea?oa aeiaiaiai iii?oi?eiao iniiaieo ?ioaa?aeueieo iieaciee?a oeoieiai-eeoeiaiai o?aeoo” aeicaiey? aea/eoe aieea niiniao aeeooy ? oa?/oaaiiy ia ??aaiue oeoieiaiai eeneioiooai?aiiy, ?ic?iaeoe ?iaeea?aeoaeuei? ?aeiiaiaeaoe?? uiaei ?aaeeio oa?/oaaiiy ? i?aoe? aeey eiie?aoiiai oai?iai. 4. Noi?ioeueiaai? i?eioeeie aeeoa?aioe?eiaaiiai canoinoaaiiy oa?iaeieia?/ieo cania?a i?e oacieo aeene?iac?yo aano?iaeoiaeaiaeueii? ciie, ye? aecia/athoue iieacaiiy aeey aeei?enoaiiy i?aia?ao?a i?ney ?o ?iaeea?aeoaeueiiai oanooaaiiy. 5. O oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee i?e a?ia?oeeeeia?e ? a?ia?oaci?e iioi?eoe? a ii?aeiaii? c iecueeeie cia/aiiyie ?I oeoiea ? i?aeaeuaiei oaciei aano?iaeoiaeaiaeueiei oeneii aeioe?eueii canoiniaoaaoe oaiioeaeei aai iiai?acie. I?e a?iioeeeeia?e ? a?iioaci?e aano?iaeoiaeaiaeuei?e iioi?eoe? c a?aenooi?noth III oace a ii?aeiaii? c ii?ooaiei aioo??oiueiii?iaeieiiei oeneii o?aaa i?ecia/aoe i?ie?iaoee iio?e?oi. NIENIE ?IA?O, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1. ?aoaoeeia TH.E., E?aica? A.A. Oa?iaeieiae/aneay ei??aeoeey aeia?aoeeaeiuo ninoiyiee o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee //Aeooaeuei? ieoaiiy oa?iaoeaaoe/ii? oa iaaee/ii? iaoee oa i?aeoeee: Ca. iaoe. no. – Caii??aeaey, 1997. - Aei. 1. – N. 251 – 256. 2. E?aica? A.A. Iaoiae ioeaiee yooaeoeaiinoe ?acee/iuo eeneioiaeiee?othueo i?aia?aoia // Aeooaeuei? ieoaiiy oa?iaoeaaoe/ii? oa iaaee/ii? iaoee oa i?aeoeee: Ca. iaoe. no. – Caii??aeaey, 1999. - Aei. 3. – N. 219-221. 3. E?aica? A.A. Oa?iaeieiae/aneay ei??aeoeey aano?iaeoiaeaiaeueiuo aeeneeiacee o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee // Aeooaeuei? ieoaiiy oa?iaoeaaoe/ii? oa iaaee/ii? iaoee oa i?aeoeee: Ca. iaoe. no. – Caii??aeaey, 1999. - Aei. 4. – N. 191 –195. 4. ?aoao?eia TH.?., Aeieo???aa N.I., E?aica? I.I. Oa?iaeieia?/i? i?iae i?e i?aeai?? ?iaeea?aeoaeueiiai e?eoaaiiy caoai?thaaiue oeoiea ? aeaaiaaeoeyoeiaei? eeoee // Oa?iaeii. – 1999. - ?1. – N. 51-53. 5. Iao. 22852 A Oe?a?ia, IEE6 A61A 5/00. I?eno??e aeey aeiaiaiai iii?oi?oaaiiy iniiaieo ?ioaa?aeueieo iieaciee?a oeoieiai-eeoeiaiai o?aeoo / ?aoao?eia TH.?., Aeieo???aa N.I., E?aica? I.I., I?ioeaiei I.I. – Cayae. 17.12.96; Iioae. 5.05.98. 6. ?aoao?eia TH.?., Aeieo???aa N.I., E?aica? I.I. Aieea aioenae?aoi?ieo i?aia?ao?a ia noai aano?iaeoiaeaiaeueii? iioi?eee i?e e?eoaaii? ae?aceiai? oai?iae o i?aee?oe?a // E?ee Oe?a?ie.– 1999.- ?5.– N.74– 75. 7. ?aoao?eia TH.?., Aeieo???aa N.I., E?aica? I.I. Oacia oeueo?aniiia?ao?y i?aai?a o?aaeaiiy i?e ae?aceia?e oai?ia? aeaaiaaeoeyoeiaei? eeoee o ae?oae oa i?aee?oe?a// Oe?. ?aae?ieia?/iee aeo?i. – 1999. - ?3. – N.244 - 246. 8. ?aoaoeeia TH.E., E?aica? A.A. N?aaiaiea yooaeoeaiinoe ?acee/iuo eeneioiaeiee?othueo i?aia?aoia a eo?niaii ea/aiee ycaaiiie aieacie// Aano?iaioa?ieia?y: I?aea?ae. ca. – Aei?i?iiao?ianuee, 1999.- Aei. 28. – N. 240-242. 9. E?aica? A.A. Aeeaaiinoeea ia?ooaiee aano?iaeoiaeaiaeueiie iioi?eee o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee// Aano?iaioa?ieia?y: I?aea?ae.ca.–Aei?i?iiao?ianuee,1999.-Aei.29.–N.113-117. 10. E?aica? A.A. Iaoiae aeeaaiinoeee iniiaiuo eioaa?aeueiuo ooieoeee aeaeoaei/ii – eeoa/iiai o?aeoa // Aano?iaioa?ieia?y: I?aea?ae. ca. – Aei?i?iiao?ianuee, 1999.- Aei.29. – N. 117-119. 11. ?aoaoeeia TH.E., E?aica? A.A., Aeieo?eaaa N.I. Eiaeeaeaeoaeueiue iaeiioeeeeiaie oaciue e nooi/iue oaciue iiieoi?eia iaeiia?aiaiiiai aeeyiey i?aia?aoia ia ?I, iioi?eeo, aioo?eiieinoiia aeaaeaiea o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee //Aeooaeuei? i?iaeaie aioo??oiuei? iaoieia?? oa i?neyaeeieiiii? i?aeaioiaee e?ea??a–oa?aiaao?a. – E., 1996.–N.249–250. 12. ?aoao?eia TH.?., E?aica? I.I., Aeieo???aa N.I. Aeiaiaa iii?oi?oaaiiy oa eiiieaenia iie?iao??y - iaeno/ani?o? iaoiaee ae?aaiinoeee aano?iaioa?ieia?/ieo caoai?thaaiue //Aeooaeuei? i?iaeaie aioo??oiuei? iaoieia?? oa i?neyaeeieiiii? i?aeaioiaee e?ea??a – oa?aiaao?a. – E., 1996. – N. 250 – 251. 13. Reshetilov U., Kremzer A., Dmitrieva S. Daily dyspensary monitoring of inner cavity pH motility of duodenum // ?in. aeo?i. Aano?iyioa?ieiaee, aaiaoieiaee, eieii?ieoieiaee. – I., 1996.- O. VI , ? 4. – N.70. 14. ?aoaoeeia TH.E., E?aica? A.A. Iooe i?eaia e a?aiy aeaenoaey i?aia?aoia, aeeythueo ia eeneioiia?acothuoth ooieoeeth aeaeoaeea //I?aoe? ae?oaiai oe?. oeaeiy aano?iaioa?ieia?a.– Aei?i?iiao?ianuee, 1997.– N.108-109. 15. ?aoaoeeia TH.E., E?aica? A.A. Iaoiae eiaeeaeaeoaeueiiai iiaeai?a I2-aeieaoi?ia aeey oniaoiie ei??aeoeee aeia?aoeeaeiuo ninoiyiee o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee //?in. aeo?i. aano?iyioa?ieiaee, aaiaoieiaee, eieii?ieoieiaee. – I., 1997. - O. VII, ?5. – N.73. 16. E?aica? A.A. Canoinoaaiiy aeiaiaiai iii?oi?oaaiiy oa eiiieaenii? iie?iao??? //Iaoeia? i?aoe? Caii??cueeiai aea?aeaaiiai ?inoeoooo oaeineiiaeaiiy e?ea??a i?enay/ai? 70-??/iiio tha?eath ?inoeoooo. - Caii??aeaey, 1997.- N. 93-94. 17. E?aica? A.A. Iaoiae eiaeeaeaeoaeueiiai iiaeai?a I2-aeieaoi?ia aeey ei??aeoeee aeia?aoeeaeiuo ninoiyiee o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee //Iaoeia? i?aoe? Caii??cueeiai aea?aeaaiiai ?inoeoooo oaeineiiaeaiiy e?ea??a i?enay/ai? 70-??/iiio tha?eath ?inoeoooo. - Caii??aeaey, 1997.- N. 94-95. 18. ?aoao?eia TH.?., Eoci?oeiaa E.I., Eeaaae??aa I.TH., E?aica? I.I., No?ieei I.I., I?ioeaiei I.I., Oiea?aiei I.?. No/aniee iiaeyae ia ae?aaiinoe/i? oa e?eoaaeuei? iiaeeeaino? iioaciiai aeoiaeaiaeueiiai ciiaeoaaiiy//Iaoa??aee XIV c’?caeo oa?aiaao?a Oe?a?ie.– E., 1998. –N.420-421. AIIOAOe?ss E?aica? I.I. Ae?aaiinoeea oaciiai oeoieiaiai eeneioiooai?aiiy oa e?eoaaiiy oacieo aano?iaeoiaeaiaeueieo aeene?iac?e o oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee. – ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.02 – aioo??oi? oai?iae. – Caii??cueeee ?inoeooo oaeineiiaeaiiy e?ea??a, Caii??aeaey, 1999. A oiiaao aano?iaioa?ieia?/ii? ee?i?ee aoei ianoaaeaii 135 oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee. Aea/aia ee?i?/ia ea?oeia ia?aa?ao caoai?thaaiiy, ee?i?/i? iniaeeaino? a caeaaeiino? a?ae oeio aano?iaeoiaeaiaeueii? aeene?iac??; aea/ai? iniaeeaino? iioi?ii? ae?yeueiino? aeaaiaaeoeyoeiaei? eeoee o oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee. Anoaiiaeaii, /oi o 85% oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee cono??/athoueny noiooi? aano?iaeoiaeaiaeuei? aeene?iac??. Cai?iiiiiaaiee niin?a oanooaaiiy ?ai?oeaeeio, oaiioeaeeio, iiai?acieo oa iio?e?oio oeyoii ?o noae?iaaaeueiiai oaaaeaiiy aeicaiey? ca 90 oaeeei i?ae?a?aoe ?acia? oa eo?nia? oa?aiaaoe/i? aeice oeeo i?aia?ao?a. Eeth/ia? neiaa: aeaaiaaeoeyoeiaea eeoea, ae?aceiaa oai?iaa, oacia iioi?eea, eeneioi?noue, ?I, aeene?iac?y, a?ia?e?iac?y, a?iie?iac?y, oaiioeaeei, ?ai?oeaeei, iiai?acie, iio?e?oi. AIIIOAOeEss E?aica? A.A. Aeeaaiinoeea oaciiai aeaeoaei/iiai eeneioiia?aciaaiey e ea/aiea oaciuo aano?iaeoiaeaiaeueiuo aeeneeiacee o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee. – ?oeiienue. Aeenna?oaoeey ia nieneaiea iao/iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.02 – aioo?aiiea aieacie. - Caii?iaeneee einoeooo oniaa?oainoaiaaiey a?a/ae, Caii?iaeuea, 1999. A oneiaeyo aano?iyioa?ieiae/aneie eeeieee auei ianeaaeiaaii 135 aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee. Eco/aia eeeie/aneay ea?oeia caaieaaaiey, aai eeeie/aneea iniaaiiinoe a caaeneiinoe io oeia aano?iaeoiaeaiaeueiie aeeneeiacee; onoaiiaeaiu iniaaiiinoe iioi?iie aeayoaeueiinoe aeaaiaaeoeaoeia?noiie eeoee o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee. Onoaiiaeaii, /oi o 85% aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee ioia/athony niioonoaothuea aano?iaeoiaeaiaeueiua aeeneeiacee. I?aaeeiaeaiiue niinia oanoe?iaaiey ?aieoeaeeia, oaiioeaeeia, iiai?aciea e iioeeeoia iooai eo noaeeiaaaeueiiai i?eaia iicaieyao ca 90 ieioo iiaeia?aoue ?aciaua e eo?niaua oa?aiaaoe/aneea aeicu yoeo i?aia?aoia. Eeth/aaua neiaa: aeaaiaaeoeaoeia?noiay eeoea, ycaaiiay aieaciue, oaciay iioi?eea, eeneioiinoue, ?I, aeeneeiacey, aeia?eeiacey, aeiieeiacey, oaiioeaeei, ?aieoeaeei, iiai?acie, iioeeeoi. SUMMARY Kremzer A.A. Diagnostics phasal stomach acidity and treatment of phasal gastroduodenal dyskinesia in patients with duodenal ulcer. – Manuscript. Thesis for a candidate degree on the speciality 14.01.02 – internal diseases – Zaporozhye institute of doctor’s advanced training, Zaporozhye, 1999. Before the present time the results of diagnostics and treatment of peptic ulcer seems to be inadequate. The part of diagnostic mistakes and recurrences of this disease is still very high. In our honour opinion among the basical methods of peptic ulcer diagnostics we can mention endoscopical investigations, Roe-graphy, manometry, pH – metry, ultrasonical investigations. But sometimes this bread list of methods can’t give rough answer about the conditions of peptic ulcer recurrence. That’s why – new, perspective methods of it’s diagnostics is very actual. We were going to: determine and to reveal intercommunication of inner cavity pressure of duodenum and stomach; to determine and reveal interdependence of daily motility of duodenum and stomach; to determine and to reveal interdependence of daily pH of duodenum and stomach; to provide pharmacological monitoring of ulcer cicatrising. In the conditions of gastroenterology clinic there were observed 135 patients with duodenal ulcer and 15 healthy volunteers. It was studied the clinics of the disease, it’s clinical particularities in dependence of duodenal motility type; it was revealed the particularities of duodenal motility in patients with duodenal ulcer. We create a diagnostic instrument, consists of probe – 5mm in diameter with indices of pressure and pH, computer’s complex, chart of daily monitoring of inner cavity pressure, motility and pH. Heaving observed healthy people in interdigestive and digestive periods, we investigate directly ad inversely proportional hour and a half and daily dependencies of gastroduodenal motility and pressure. Concerning those, with ulcer diseased duodenum in the periods mentioned above, observation revealed only directly proportional hour and a half and daily dependencies of gastroduodenal pressure, motility and pH. On the rich experimental material it has been shown the most rational approaches on prescription of antiacidic drugs in case of hyperacidic conditions and motility disorders in patients with duodenal ulcer. It has been shown, that standard dosage of antiacidic drugs is often not enough to reduce highly increased acidity in patients with peptic ulcer. Daily medical monitoring helps to cicatrise duodenal peptic ulcer in extremely early terms. First time we propose to use sublingual method of antiacidic drug prescription. Our results of comparing between sublingual and traditional method of using stressed, that sublingual method of use lets achieve the beginning of drug action earlier, than in the case of traditional prescription, while it’s action lasts almost the same time, as in traditional drug taking. According to our investigations testing of corresponding duodenal dyskinesia, revealing the level of stomach acidity, daily monitoring with the prescription of suitable antiacidic drug will greatly improve the treatment of duodenal ulcer, it will short the time of it’s cicatrising. Key words: duodenum, peptic ulcer, motility, acidity, ?I, dyskinesia, hyperkinesia, hypokinesia, famotidin, ranitidin, omeprazol, motilium.

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