Антимікробні розсмоктувальні полімерні матеріали в плановій та ургентній абдомінальній хірургії: Автореф. дис… д-ра мед. наук / В.Б. Гощинський, Нац

IAOe?IIAEUeIEE IAAeE*IEE OI?AA?NEOAO

?i. I. I. AIAIIIEUeOess

Ia i?aaao ?oeiieno

oaee: 617.55 — 089.168.1 – 06: 616 — 005.1 + 616 – 005.6 + 615.468.6

Aiueinueeee Aieiaeeie? A?ii?neaaiae/

AIOEI?E?IAI? ?ICNIIEOOAAEUeI? IIE?IA?I? IAOA??AEE A IEAIIA?E OA
O?AAIOI?E AAAeII?IAEUeI?E O??O?A??

14.01.03 — o??o?a?y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai
nooiaiy

aeieoi?a iaaee/ieo
iaoe

ee?a — 1998

Aeena?oaoe?y ? ?oeiienii

?iaioa aeeiiaia a Oa?iii?euenuee?e aea?aeaai?e iaaee/i?e aeaaeai??

?i.?.ss.Ai?aa/aanueeiai

Iaoeia? eiinoeueoaioe: aeieoi? iaaee/ieo iaoe, i?ioani? eaoaae?e
caaaeueii?

o??o?a?? Oa?iii?euenueei?
aea?aeaaii? iaaee/ii? aeaaeai??

Iieion TH??e Ieoaeeiae/

caneoaeaiee ae?y/ iaoee ? oaoi?ee aeieoi?
iaaee/ieo iaoe,

i?ioani?, Caa?aeoaa/
aenia?eiaioaeueiei a?aeae?eii

?inoeoooo ee?i?/ii? oa
aenia?eiaioaeueii? o??o?a?? AII

Oe?a?ie Oo?iaiia TH??e
Ieaenaiae?iae/

Io?oe?ei? iiiiaioe: aeaaeai?e IAI oa AII Oe?a?ie, aeieoi? iaaee/ieo
iaoe,

i?ioani?, ii/aniee aee?aeoi?
?inoeoooo ee?i?/ii? oa

aenia?eiaioaeueii? o??o?a?? AII
Oe?a?ie Oae?iia

Ieaenaiae? Ieaen?eiae/

aeieoi? iaaee/ieo iaoe, i?ioani?,
caa?aeoaa/ eaoaae?e

o??o?a?? noiiaoieia?/iiai
oaeoeueoaoo Iaoe?iiaeueiiai

iaaee/iiai oi?aa?neoaoo
?i.I.I.Aiaiiieueoey Ooo/aiei

Ieeiea ?aaiiae/

aeieoi? iaaee/ieo iaoe, i?ioani?
eaoaae?e oi?aei-

aaaeii?iaeueii? o??o?a??
Ee?anueei? iaaee/ii? aeaaeai??

i?neyaeeieiiii? ina?oe Iie?ieaae/
A?ii?neaa

Noai?neaaiae/

I?ia?aeia onoaiiaa: Oa?e?anueeee iaoeiai-aeine?aeiee ?inoeooo caaaeueii?
oa

iaa?aeeeaaeii? o??o?a?? IIC Oe?a?ie

Caoeno a?aeaoaeaoueny «____»_________» 1998 ?. I______aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.003.03 i?e
Iaoe?iiaeueiiio iaaee/iiio oi?aa?neoao? ?i.I.I.Aiaiiieueoey, 252004,
Ee?a, aoeueaa? Oaa/aiea 17.

C aeena?oaoe??th iiaeia iciaeiieoenue a a?ae?ioaoe? iaaee/iiai
oi?aa?neoaoo ca aae?anith: 252057, Ee?a, aoe. Ciieia?/ia 1.

Aaoi?aoa?ao ?ic?neaiee «____»____________1998 ?.

A/aiee nae?aoa? niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe, i?ioani? Ai?enaiei
A.A.

CAAAEUeIA OA?AEOA?ENOEEA AeENA?OAOe??

Aeooaeuei?noue oaie:

I?neyiia?aoe?ei? oneeaaeiaiiy a aaaeii?iaeuei?e o??o?a?? ia iathoue
oaiaeaioe?? aei ciaioaiiy. Iaa?oue i?e ?aeaaeuei?e oaoi?oe? iia?aoe?e
o??o?a ia cano?aoiaaiee a?ae oe?eiai ?yaeo oneeaaeiaiue. Oae, iino?eia
i?enooi?noue i?e?iaiiai oaeoi?a a cii? oi?ioaaiiy aianoiiic?a, ca?eueoo?
nooi?iue caiaeueii? ?aaeoe?? a oeaieiao, ui i?eaiaeeoue aei iia??oaiiy
?aaaia?aoeaieo i?ioean?a (Aeania A. I. 1991, Eanueyiiaa O. N. 1989,
Shapiro S. I. 1980). 3 ae?oaiai aieo, iayai?noue ia?icniieooaaeueiiai
oiaiiai iaoa??aeo noai?th? aeiaeaoeiaa aeaea?aei o?ii?/iiai caiaeaiiy
(Ainoeuaa A. E. e niaao., 1985). Aca?iiae?y oeeo oaeoi??a cia/ii
iineaaeth? iaoai?/io i?oei?noue oa aa?iaoe/i?noue oa?a oa aianoiiic?a,
ui i?eaiaeeoue aei iani?iiiaeiino? inoaii?o, ?icaeoeo caiaeueieo
?io?eueo?ao?a oa ceoeiaeo i?ioean?a (Aeania A. I., 1991, A?thoei E. A.,
1989, Caii?iaeaoe A. A., 1989). Oe?eee ?yae oaeeo oneeaaeiaiue, ye
aianoiiiceoe, aeaoi?iaoe?y aianoiiic?a, oiai? a?aioeueiie, e?aaoo?i?
ii?eoe?, e?aaoo?iee oieae?o?ac iia’ycothoue c aeei?enoaiiyi
ia?icniieooaaeueiiai oiaiiai iaoa??aeo (Aieuineee I.A, e niaao., 1984,
Aiaeeaaneee A. E., e niaao., 1995, Eaieei E. A. e niaao., 1987, 1989).

?ioaineai? iaoeia? ?ic?iaee ii noai?aiith a?eueo aeineiiaeueiiai oiaiiai
iaoa??aeo i?eaaee aei neioaco ?icniieooaaeueieo ieoie: aeaeniio,
iie?aeaeoei-910-a?e?eeo, iie?ae?ienaiiio, iaeniio (caei?aeiii?) oa
ieoeaeiio, eaoeaeiio, ?ai?io, eai?iiaaeo (a?o/eciyi?). ?o canoinoaaiiy a
o??o?a?? oeoieiai-eeoeiaiai o?aeoo cia/ii ciaioeei e?euee?noue
i?neyiia?aoe?eieo oneeaaeiaiue.

Iaeiae, c iaoith iiia?aaeaeaiiy i?neyiia?aoe?eieo oneeaaeiaiue, a oiio
/ene? ? ai?eii-caiaeueiiai oa?aeoa?o, a?eueo aoaeoeaiei aoei ae
aeei?enoaiiy ieoie oe?eani?yiiaaii? aioei?e?iaii? ae??. Iaiao?aei?noue
aeei?enoaiiy oeueiai oeio ieoie iaoiiaeth?oueny i?enooi?noth i?e?iaiiai
oaeoi?a a cii? aianoiiic?a i?ae /an ?o oi?ioaaiiy i?e «/enoeo»
iia?aoe?yo, oa cia/iei ca?eueoaiiyi «i?e?iaiiai» /enea i?e aeeiiaii?
o?aaioieo iia?aoe?e. A aeayeeo neooaoe?yo (aiai?y, iieiiaoieia?y,
i?ei?inoaiic, iioeeee a?e oai?iai) aeieea? iaiao?aei?noue ia o?eueee a
aioeaaeoa??aeuei?e ae?? ieoie, aea ? a noeioeyoe?? ?aia?aoeaieo
i?ioean?a o oeaiei?.

C ae?oaiai aieo, caeeoathoueny ia aecia/aieie iieace aei ?o
canoinoaaiiy, ia ?ic?iaeai? iaoiaeeee iiia?aaeaeaiiy i?neyiia?aoe?eieo
oneeaaeiaiue ca aeiiiiiaith aioei?e?iaieo iie?ia?ieo iaoa??ae?a.

Iaoa aeine?aeaeaiiy:

Iie?auaiiy ?acoeueoao?a iia?aoeaieo ao?o/aiue a ieaiia?e oa o?aaioi?e
aaaeii?iaeuei?e o??o?a?? oeyoii iiia?aaeaeaiiy ai?eii-caiaeueieo oa
oiaieo oneeaaeiaiue ca aeiiiiiaith aioei?e?iaieo ?icniieooaaeueieo
iie?ia?ieo iaoa??ae?a.

Caaaeaiiy aeine?aeaeaiiy:

Aecia/eoe o?ceei-iaoai?/i? oa aioei?e?iai? aeanoeaino? ieoie Eai?iiaae
AA, Eai?iiaae AAeO, Eai?iiaae IA, Eai?ieiae.

Aeaoe ii??aiyeueio ioe?ieo caai?iiy eeoeiaeo aianoiiic?a oa iaoai?/io
i?oei?noue i?e oi?ioaaii? ?o ca aeiiiiiaith eai?iiia? ieoee, ieoie
Eai?iiaae, Eai?iiaae AAeO, Eai?iiaae IA, Eai?ieiae.

Aecia/eoe oa?i?i a?iaeano?oeoe?? ieoie Eai?iiaae AAeO, Eai?iiaae IA,
Eai?ieiae.

?ic?iaeoe iaoiaeeeo oi?ioaaiiy oeoieiai-eeoeiaeo, oiiei-oiiei,
oiiei-oianoi, oianoi-oianoieeoeiaeo oa a?e?iaeeaanoeaieo aianoiiic?a ca
aeiiiiiaith ieoie Eai?iiaae AAeO, Eai?iiaae IA, Eai?ieiae a ieaiia?e oa
o?aaioi?e o??o?a??.

Noai?eoe iaoiaeeeo iiia?aaeaeaiiy iani?iiiaeiino? oa?a oa aianoiiic?a ca
aeiiiiiaith eiia?iaoe?? aioei?e?iaia ?icniieooaaeueia ie?aea — eeaeiaa
eiiiiceoe?y — aioei?e?iaia ?icniieooaaeueia ieoea i?e ia?eoii?o?.

Aecia/eoe iieace aei canoinoaaiiy aioei?e?iaieo iie?ia?ieo
?icniieooaaeueieo iaoa??ae?a a caeaaeiino? a?ae iaaii? o??o?a?/ii?
neooaoe??.

I?iaanoe ii??aiyeueio ioe?ieo ?acoeueoao?a iia?aoeaieo ao?o/aiue ?c
canoinoaaiiyi aioei?e?iaieo ?icniieooaaeueieo iie?ia?ieo iaoa??ae?a c
oaeeie iia?aoeaieie ao?o/aiiyie, ye? i?iaaaeai? ca o?aaeeoe?eiith
iaoiaeeeith.

IAOEIAA IIAECIA IAeA?AEAIEO ?ACOEUeOAO?A

Aia?oa i?iaaaeaia ii??aiyeueia ii?oieia?/ia ioe?iea aieeao ia
?aaaia?aoeaiee i?ioean a o??o?a?/ieo ?aiao eai?iiiai? ieoee, ieoie ia?ie
Eai?iiaae, Eai?iiaae AAeO, Eai?iiaae IA, Eai?ieiae, yea aeyaeea
iniaeeaino? aieeao ia oeae i?ioean eiaeii? ia?ee ieoie, a oaeiae
niaoeeo?/i?noue ?o aioeaaeoa??aeueii? ae??.

Aia?oa aioeaaeoa??aeuei? ?icniieooaaeuei? ieoee oe?eani?yiiaaii
canoiniaai? aeey iiia?aaeaeaiiy i?neyiia?aoe?eieo oneeaaeiaiue
aaaeii?iaeuei?e o??o?a?? oa i?iaiae?ciaaia aoaeoeai?noue ?o ae??.

Aia?oa ?ic?iaeaii oa ai?iaaaeaeaii a i?aeoeeo aaaeii?iaeueii? o??o?a??
eiiieaen aioeaaeoa??aeueia ?icniieooaaeueia ie?aea — eeaeiaa eiiiiceoe?y
— aioeaaeoa??aeueia ?icniieooaaeueia ieoea aeey iiia?aaeaeaiiy
iani?iiiaeiino? no?aaio?aeii-eeoeiaeo aianoiiic?a, oa?a aaaeei? eoene
aeaaiaaeoeyoeiaei? eeoee, o?iaaeiiiae?aiiai ia?inoea, oa?a oa
aianoiiic?a, ye? noi?iiaai? i?e ia?eoii?o? ia ii?iaeienoeo i?aaiao.

Aia?oa aecia/ai? iieacaiiy aei canoinoaaiiy eiaeii? ia?ee ieoie oa
ie?aee a caeaaeiino? a?ae iaaii? o??o?a?/ii? neooaoe??.

OAI?AOE*IA CIA*AIIss ?ACOEUeOAO?A AeINE?AeAEAIIss

Iaoeiaa ?iaioa c?iaeaia ia iaae? o?ceee, a?ieia??, iaaeeoeeie. Aaoi?ii
aeyaeai? o?ceei-iaoai?/i?, i?ioei?e?iai? aeanoeaino? iiaeo
?icniieooaaeueieo neioaoe/ieo aioeaaeoa??aeueieo ieoie, oaeei /eiii,
c?iaeaii nooo?aee aianie a oai?aoe/i? iniiae neioaco ?icniieooaaeueieo
iie?ia??a oe?eani?yiiaaii? a?ieia?/ii? ae??.

Iaea?aeai? iia? aeai? c ii?oieia?? ?aiaaiai i?ioeano, yeee ia?aa?aa? ia
oe? aioeaaeoa??aeueiiai ?icniieooaaeueiiai oiaiiai iaoa??aeo. ?iaeoueny
aaaeeeaee oai?aoe/iee aeniiaie i?i oa, ui aioei?e?iaiee
?icniieooaaeueiee oiaiee iaoa??ae (A?OI) ? caniaii aieeao ia ?aiaaee
i?ioean, ui iaaeeaea? eiai aei anaioe/iiai.

?ic?iaeaia iaoiaeeea oi?ioaaiiy eeoeiaiai oaa ca aeiiiiiaith A?OI oa
cai?iiiiiaaia iaoiaeeea iiia?aaeaeaiiy iani?iiiaeiino? oa?a a oiiaao
ia?eoii?oo.

Aecia/ai? oeyoe ?aae?caoe?? iiaiai A?OI a aaaeii?iaeuei?e o??o?a?? oa
iieace eiai canoinoaaiiy a caeaaeiino? a?ae eiie?aoii? o??o?a?/ii?
neooaoe??. Iaoa??aee aeena?oaoe?? aaaaeaii a iaa/aeueio i?ia?aio c
caaaeueii? oa oaeoeueoaonueei? o??o?a??, o??o?a?? OII Oa?iii?euenueei?
aea?aeaaii? iaaee/ii? aeaaeai??.

I?AEOE*IA CIA*AIIss ?ACOEUeOAO?A AeINE?AeAEAIIss

Aeey i?aeoe/ii? aaaeii?iaeueii? o??o?a?? i?iiiio?oueny i?inoee ? a oie
aea /an iaae?eiee iaoiae iiia?aaeaeaiiy i?neyiia?aoe?eieo oneeaaeiaiue
ca aeiiiiiaith aioei?e?iaieo ?icniieooaaeueieo iie?ia?ieo iaoa??ae?a,
yeee aea? iiaeeea?noue ciaioeoe e?euee?noue oneeaaeiaiue
ai?eii-caiaeueiiai oa?aeoa?o oa oneeaaeiaiue, iia’ycaieo c
ia?icniieooaaiiyi oiaiiai iaoa??aeo, iie?aueoe ooieoe?iiaeuei?
?acoeueoaoe.

I?iiiio?oueny iaa?? ??cieo ia?ie aioei?e?iaieo ?icniieooaaeueieo ieoie
ia?ee Eai?iiaae A, aeei?enoaiiy yeeo iiaeeeaa naiino?eii aai a
eiia?iaoe?? c aioei?e?iaieie ?icniieooaaeueieie ie?aeaie a?aeiia?aeii
aei ??ciiiai?oieo o??o?a?/ieo neooaoe?e, ui aacoiiaii i?aeaeuo?
aoaeoeai?noue oa aaciaeo iia?aoeaieo ao?o/aiue.

AI?IAAAeAEAIIss ?ACOEUeOAO?A AeINE?AeAEAIIss A I?AEOEEO IOI?IIE
CAeI?IA’ss

Ca iaoa??aeaie iaoeiai? ?iaioe aeaeai? aeaa ?anioae?eainueeeo
?ioi?iaoe?eieo eenoa. ?acoeueoaoe iaoeiaeo ?ic?iaie ai?iaaaeaeaii a
i?aeoeeo o??o?a?/ieo a?aeae?eaiue Oa?iii?euenueei? iaeanii? e?ea?i?,
Oa?iii?euenueeeo ee?i?/ieo e?ea?iyo ?1, 2, Ooinuee?e oa Ai?u?anuee?e
?aeiiieo e?ea?iyo, ?iaainueeee oa AEeoiie?nuee?e iaeanieo e?ea?iyo,
AEeoiie?nuee?e i?nuee?e e?ea?i? ? 1.

INIAENOEE AIANIE CAeIAOAA*A

?aeay iaoeiai? ?iaioe, iaoiaee ?aae?caoe?? iinoaaeaieo caaaeaiue
cai?iaaaeaeai? aeena?oaioii. Iei naiino?eii i?iaaaeai? aenia?eiaioaeuei?
aeine?aeaeaiiy, iia?iaaii 60% oai?eo, c?iaeaii aiae?c iaea?aeaieo
?acoeueoao?a, noi?ioeueiaaii aeniiaee, cai?iiiiiaai? i?aeoe/i?
?aeiiaiaeaoe??. Aeena?oaioo iaeaaeeoue 70% ?aeae oa ?ic?iaie o ni?eueieo
iaoeiaeo i?aoeyo.

AI?IAAOe?ss ?ACOEUeOAO?A AeENA?OAOe??

Iaoa??aee aeena?oaoe?? aeeeaaeai? ia XX ieaioi? Ananithciiai iaoeiaiai
oiaa?enoaa o??o?a?a (Euea?a, 1985), Ananithci?e oeie? «Iieeia?iua
iaoa?eaeu iaaeeoeeineiai iacia/aiey» (Iineaa, 1988), iaeani?e iaoeia?e
eiioa?aioe?? «Iia? iaoiaee ae?aaiinoeee, e?eoaaiiy, i?io?eaeoeee»
(Oa?iii?eue, 1989), caaaeueiioe?a?inueeiio neiiic?oi? «Aeooaeuei?
ieoaiiy o??o?a?? a na?oe? iniaenoiai aeina?aeo» (Oa?iii?eue, 1993), ia
i?aeiaeani?e eiioa?aioe?? «?ioaineaia oa?ai?y ? aoa?aioi? iaoiaee
aeaoieneeaoe?? i?e ai?eii-naioe/ieo caoai?thaaiiyo (Oa?iii?eue, 1993),
iaoeia?e eiioa?aioe?? «Aeooaeuei? ieoaiiy ee?i?/ii? ? aenia?eiaioaeueii?
iaaeeoeeie» (Oa?iii?eue, 1994), ia can?aeaii? anioe?aoe?? o??o?a?a
iaeano? (Oa?iii?eue, 1994), OVII c’?cae? o??o?a?a Oe?a?ie (Euea?a,
1994), ia iaoeia?e eiioa?aioe?? «Aeinyaiaiiy ? ia?niaeoeae ee?i?/ii? ?
aenia?eiaioaeueii? iaaeeoeeie (Oa?iii?eue, 1995), ia iaoeiai-i?aeoe/i?e
eiioa?aioe?? «No/ani? aniaeoe iaa?aeeeaaeii? iaaee/ii? aeiiiiiae»
(Euea?a, 1997), ia i?aenoieia?e iaoeia?e eiioa?aioe?? i?enay/ai?e
40-??/iiio tha?eath Oa?iii?euenueei? iaaee/ii? aeaaeai?? (Oa?iii?eue,
1997).

CA’ssCIE CAAAeAIUe AeINE?AeAEAIIss C I?IAEAIIEI IEAIII

IAAeE*IEO IAOE

Aeena?oaoe?y aoea o?aaiaioii Ananithcii? aaeocaai? i?ia?aie N-11
«Iaoa?eaeu oiaiua oe?o?ae/aneea eai?iiiaua n iieeia?iui iie?uoeai,
niaea?aeauai aioeiee?iaiua e niinianoaothuea ?aaaia?aoeee aauanoaa» oa
o?aaiaioii eiiieaenii? iaoeiai-aeine?aeii? ?iaioe, yea aeeiioaaeanue
ca?aeii c ieaiii IAe? Oa?iii?euenueei? aea?aeaaii? iaaee/ii? aeaaeai??
(iiia? aea?aeaaii? ?a?no?aoe?? 0195 — ?V 009228).

IOAE?EAOe??

Ca oaiith aeena?oaoe?? iioae?eiaaii 32 iaoeiaeo i?aoeue, ?c ieo 5
i?aoeue, iaienaieo iaeiiin?aii, iioae?eiaaii a ?aeiiaiaeiaaieo
aeo?iaeao.

INIIAI? IIEIAEAIIss, AeENA?OAOe??, UI AEIINssOUeNss IA CAOENO

Aioei?e?iai? ?icniieooaaeuei? ieoee ca nai?ie o?ceei-iaoai?/ieie
aeanoeainoyie a?aeiia?aeathoue aeiiaai uiaei ?icniieooaaeueiiai oiaiiai
iaoa??aeo.

Aioei?e?iai? ?icniieooaaeuei? ieoee Eai?iiaae AA, Eai?iiaae AAeO,
Eai?iiaae IA, Eai?ieiae iathoue oe?eani?yiiaaio aioei?e?iaio ae?th.

Oi?ioaaiiy oa?a oa aianoiiic?a ia ii?iaeienoeo i?aaiao o?aaiiai o?aeoo
ca aeiiiiiaith A?OI ni?ey? ciaioaiith caiaeueii? ?aaeoe??, ui ii?iae?co?
?aaaia?aoeai? i?ioeane o oeaieiao.

Canoinoaaiiy A?OI ca?eueoo? a?ieia?/io aa?iaoe/i?noue oa iaoai?/io
i?oei?noue aianoiiic?a.

Aeei?enoaiiy aioei?e?iaieo ?icniieooaaeueieo iie?ia?ieo iaoa??ae?a
(ieoie oa ie?aie) cia/ii ciaioo? e?euee?noue i?neyiia?aoe?eieo
oneeaaeiaiue.

IANssA OA NO?OEOO?A AeENA?OAOe??

Aeena?oaoe?y aeeeaaeaia ia 255 noi??ieao ? neeaaea?oueny ?c anooio,
iaeyaeo e?oa?aoo?e, ?icae?eo aenia?eiaioaeueieo aeine?aeaeaiue,
?icae?e?a ee?i?/ieo aeine?aeaeaiue oa ioe?iee aoaeoeaiino? aeei?enoaiiy
aioei?e?iaieo ?icniieooaaeueieo iie?ia?ieo iaoa??ae?a, caeeth/aiiy,
aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e, nienea aeei?enoaieo e?oa?aoo?ieo
aeaea?ae, ye?e aeeth/a? 332 aeaea?aea. ?iaioa ?ethno?iaaia 31 iaethieaie
oa 28 oaaeeoeyie.

CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy:

Aioei?e?iai? ?icniieooaaeuei? ieoee neioaciaai? ia iniia?
?icniieooaaeueii? ieoee Eai?iiaae o a?aeae?e? a?iiie?ia??a iaaee/iiai
i?ecia/aiiy ?in?enueeiai iaoeiai-aeine?aeiiai oa aei?iaoaaeueiiai
?inoeoooo oa iaaee/ii? oaoi?ee IIC ?O. Aioei?e?iai? aeanoeaino? ieoeai
iaaeathoueny oeyoii iaianaiiy ia ?o iiaa?oith aeiaeaoeiaiai iie?eooy
a?inoi?niiai niiie?ia?o a?i?ei??ii?aeiio oa aoo?eiaoae?eeaoo ia?ee IIA —
1, ui iaaea? ieoeai inaaaeiiiiio?eaiaioi? aeanoeaino?.

O no?oeoo?o iie?ia?o aoee aeeth/ai? aioeaaeoa??aeuei? i?aia?aoe —
aeeieneaeei-o?iieneaeei ? ieoea Eai?iiaae AAeO, aaioai?oeei, Eai?iiaae
IA, eiae, Eai?ieiae, ?aia?aio iae?ieoiaa ianei oa aaioai?oeei, Eai?iiaae
IA.

Ca?aeii iinoaaeaieo caaea/ o?ceei-iaoai?/i? aeanoeaino?
aioeaaeoa??aeueieo ?icniieooaaeueieo ieoie (e?i?eia oa aoceeeiaa
i?oei?noue, a?aeiinia iiaeiaaeaiiy, iaae?ei?noue aocea) i?iaaaeaii ia
?ic?eai?e iaoei? Inston 1026 (ae?iaieoeoaa Aiae??). Eiacaiiy ieoie
aea/aee ia iiaeaeuei?e nenoai? o aeaeyae? ieanoeie c nee?eiiiai?
?aceie, oiaueiith aei 5 ni. Aeey aecia/aiiy eai?ey?iino? oa aoaeoo
«aiioo» oiaieo iaoa??ae?a aeei?enoiaoaaee eoeueoo?e E. Coli, M — 17,
Proteus 512 ia i’yniiaioiiiiio aoeueeii? a oeo?? 106 EiA/ie. 3 iaoith
a?coae?caoe?? aenioe i?aeiyooy ??aeeie ii ieoeai aoeueeii
i?aeoa?aiaoaaee ?ic/eiii aiceio 1:5. *a?ac 24 aiaeeie ?ieoaaoe?? o
oa?iinoao?, i?e oaiia?aoo?? 37° N aei??thaaee aenioo i?aeiyooy ??aeeie.

Aeey aecia/aiiy aoaeoo «aiioo» caaa?aeai? a?ae??cee ieoie, aeiaaeeiith
aei 2 ni., ?ici?uoaaee ia aeaeoeaiiio na?aaeiaeu? Eaa?ia oa Ieinei?aaa.
*a?ac 24 aiaeeie ?ieoaaoe?? i?ae?aoiaoaaee e?euee?noue eieii?e.

Aeeiai?eo aeae?eaiiy eiaeo c ieoee Eai?ieiae o oeaieio ia/?iee aecia/aii
ia 75 a?eeo uo?ao, aaaith 180-300 a?ai?a. Aeey oeueiai, i?ae caaaeueiei
cia/oeaiiyi, ieoea aeiaaeeiith 1,5 ni ?iieaiooaaeanue a iaeio ?c aeieae
ia/?iee. Oaa?eie aeaiaeeeenue c aeine?aeo /a?ac 6, 12, 24 aiaeeie oa ia
3, 5, 7, 14, 22 aeiao oeyoii ia?aaeicoaaiiy aa?a?oo?aoaie. Aecia/aiiy
eiioeaio?aoe?? eiaeo a ia/?ioe? i?iaiaeeee ca iaoiaeii E. I. Eai?ia.
E?euee?noue ai?noo eiaeo aecia/aee niaeo?ioioiiao??th (NO-16) o
noaiaea?oieo ethaaoao. Aeey ?ic?aooieo aeei?enoiaoaaee eae?a?iai/io
e?eao. Ca noaiaea?o a?aany ?ic/ei eiaeenoiai eae?th. Iiia?aaeith ia?iaeo
aiiiaaiaoo oeaieie ia/?iee i?iaiaeeee 10% ?ic/eiii noeueoaoo oeeieo oa
0,5 ?ic/eiii ?aeeiai iao?o o ni?aa?aeiioaii? 10:1:1 c ianooiiei
oeaio?eooaoaaiiyi. I?ae eiio?ieai aoea oeaieia ia/?iee, a yeo
?iieaiooaaee ieoee Eai?iiaae.

Aecia/aiiy aeeiai?ee aeae?eaiiy aioeaaeoa??aeueieo i?aia?ao?a c ieoie
ia?ie Eai?iiaae AA, AAeO, IA i?iaaaeaii ia 63 a?eeo uo?ao aaaith a?ae
200 aei 320 a?ai. I?ae aa?a?oo?iaei ia?eicii a aeiaa? i’yce nieie
?iieaiooaaee aioeaaeoa??aeuei? ieoee, aeiaaeeiith 2 ni. Eiaeai aeaiue,
ia i?ioyc? 7 ae?a, iaoa??aee aeaeaeyee. Iio?i, a?ae??cee ieoie
?ici?uoaaee ia i’yniiaioiiiiio aaa?? c oano i?e?iaii Bac.Subtilis AONN
6633 -106 EiA/ie. *a?ac 24 aiaeeie ?ieoaaoe?? i?e oaiia?aoo?? 37°N
aei??thaaee aaee/eio cii cao?eiee ?inoo a?ey ieoie. Aioeaaeoa??aeuei?
aeanoeaino? ieoie Eai?ieiae, Eai?iiaae AA, AAeO, IA oaeiae aecia/aii in
vitro ii a?aeiioaiith aei iniiaieo caoaeiee?a o??o?a?/ii? ?ioaeoe??.
Oaa?ae? oa?/ia? na?aaeiaeua can?aaee ee?i?/ieie ooaiaie S.aureus,
Proteus, Klebsiella, P.aeruqinosae, E.coli a e?eueeino? 106 EiA/ie,
i?ney /iai ia ieo ?icoaoiaoaaee a?ae??cee ieoie, aeiaaeeiith 2 ni. *a?ac
24 aiaeeie ?ieoaaoe?? i?e oaiia?aoo?? 37°N aecia/aee ciie cao?eiee ?inoo
i?e?ii?aai?ci?a. Anueiai aeei?enoaii 32 ooaie i?e?ii?aai?ci?a.

Aieea aioeaaeoa??aeueieo ieoie ia eiioai?iaoe?th i?e?ioei?ith oa?a c?
noi?iie na?icii? iaieiiee aecia/aii ia 12 aacii?iaeieo niaaeao, aaaith
a?ae 15 aei 22 ea. I?ae aa?a?oo?aoi?iei ia?eicii aeeiioaaee 3 eieioii??
a 3/4 ae?aiao?a eeoee. Aeaoaeo a eeooe? e?ea?aeoaaee iaeii?yaeiei
na?icii-i’ycaaei aoceeeiaei oaii eai?iiiaith ieoeith oa ieoeaie
Eai?ieiae, Eai?iiaae AA. *a?ac 1, 2, 3, 4 aeiae ?iaeee ?aeaia?ioii?th.
Noa?eeueieie iaia?iaeie aeeneaie i?iiieaee e?i?th oa?a. Iio?i, aeenee
noa?aiii aiiiaai?coaaee o noa?eeuei?e nooioe?, aeiaaaeyth/e 1,0 ie
o?c?ieia?/iiai ?ic/eio. Aiiiaaiao o e?eueeino? 0,2 ie. o ia?icaaaeaiiio
oa ?icaaaeaiiio noai? a?ae 1:10 aei 1:1000 ia na?aaeiaeua Aiaei oa
oeoe?iaee i’yniiaioiiiee aaa?. Eoeueoo?e ?ieoaoaaeenue a oa?iinoao? ia
i?ioyc? aiaeeie i?e oaiia?aoo?? 37°N. I?ae?aooiee eieii?e
i?e?ii?aai?ci?a ia oa?/iaiio na?aaeiaeu? i?iaiaeeany aia?aoii ?OO-2.
Aaeoa??ieia?/ia neooaoe?y a?ey aioeaaeoa??aeueieo ieoie a cii?
aianoiiico aecia/aia a?noiaaeoa??ieia?/iei iaoiaeii aeine?aeaeaiiy ca
A?ai-Aaeaa?oii.

Iaoai?/ia i?oei?noue oiiei-oiieieeoeiaeo aianoiiic?a, noi?iiaaieo ii
oeio «e?iaoeue a e?iaoeue» ieoeaie eai?ii oa Eai?iiaae AAeO aecia/aia ia
1,3,5,7,10 aeiao i?ney iia?aoe?? iaoiaeii iiaaiieiii?an?? ia 15 niaaeao.

Aea/aiiy ii?oieia?/ieo iniaeeainoae caai?iiy oiiei-oiieieeoeiaeo
niieo/aiue a caeaaeiino? a?ae oiaiiai iaoa??aeo i?iaaaeaii ia 64
niaaeao, iaio noaoae, ??ciiai a?eo, aaaith a?ae 10 aei 30 ea. I?ae
aa?a?oo?aoiaei ia?eicii i?ney ?acaeoe?? iaaii? ae?eyiee oiiei? eeoee
oi?ioaaee aianoiiice ii oeio «e?iaoeue a e?iaoeue» iaeii?yaeiei
na?icii-i’ycaaei aoceeeiaei oaii. Ca aeiiiiiaith ieoie ia?ie Eai?iiaae,
Eai?iiaae AAeO, IA, Eai?ieiae noi?iiaaii ii 32 aianoiiica ia eiaeio
aioeaaeoa??aeueio ieoeo oa 64 eai?iiiaith ieoeith aeey eiio?ieth.
Oaa?eie aeaiaeeeenue ?c aeine?aeo oeyoii aioo??oiueiaaiiiai
ia?aaeicoaaiiy aa?a?oo?ao?a o no?iee 1, 3, 5, 7, 14, 30, 90, 160, 210
ae?a i?ney iia?aoe??.

Ee?i?/ia ai?iaaoe?y aioei?e?iaieo ?icniieooaaeueieo ieoie naiino?eii aai
a eiia?iaoe?? c aioei?e?iaieie ?icniieooaaeueieie ie?aeaie ia?ie ANAAA
oa ANAAAeO aoea i?iaaaeaia ia 545 oai?eo, a?eii a?ae 20 aei 72 ?ie?a.
AE?iie aoei 286, ae?iie 259. ?c canoinoaaiiyi aioei?e?iaieo
?icniieooaaeueieo iie?ia?ieo iaoa??ae?a (A?II) aoei aeeiiaii 298
ieaiiaeo iia?aoeaieo ao?o/aiue oa 247 o?aaioieo. Ca eiio?ieai aoei 311
oai?eo, a?eii 20-71 ?ie?a, ae?iie 160, /ieia?e?a 151, yeei aeeiiaii
aiaeia?/i? iia?aoeai? ao?o/aiiy (ieaiia? oa o?aaioi?), aea c
aeei?enoaiiyi ia?icniieooaaeueiiai oiaiiai iaoa??aeo.

Ai?iaaoe?y ??ciee ia?ie aioei?e?iaieo ?icniieooaaeueieo ieoie
i?iaiaeeeanue ca ianooiieie iai?yieaie: oi?ioaaiiy ca aeiiiiiaith ieoie
iaeiioa?iaeo aoceeeiaeo na?icii-i?aeneeciaeo no?aaio?aeiieeueiaeo
aianoiiic?a, oa?a oa aianoiiic?a ia oeoieo oa 12 iae?e eeooe?,
a?e?iaeeaanoeaieo aianoiiic?a, oiiei-oiiei, oiiei-oianoi,
oianoi-oianoieeoeiaeo aianoiiic?a, caoeaaiiy eiaea aeia/aaiai i?oo?a,
eaia?ioiiieo ?ai i?ney ieaiiaeo oa o?aaioieo iia?aoeaieo iia?aoe?e,
aa?i?iieanoeea.

Eiia?iaoe?y aioei?e?iaieo ?icniieooaaeueieo ieoie c aioei?e?iaiith
?icniieooaaeueiith ie?aeith aoea aeei?enoaia aeey aa?iaoecaoe?? oa
ci?oeiaiiy no?aaio?aeii-eeoeiaeo aianoiiic?a, «aaaeei?» eoene 12 iaei?
eeoee, oa?a oa aianoiiic?a ia ii?iaeienoeo i?aaiao, ye? aoee noi?iiaai?
ia oe? ia?eoii?oo, «aaaeei?» eoene aiaiaeeena.

Iai?yieaie aeey ie?aiiai canoinoaaiiy aioei?e?iaieo ?icniieooaaeueieo
ie?aie aoee:

aa?iaoecaoe?y eiaea aeia/aaiai i?oo?a i?e iaiiaeeeaino? oea c?iaeoe
o?aaeeoe?eiei niiniaii;

aeei?enoaiiy ie?aie aeey cae?eooy aeana?icaoe?? iiaa?oiiue eeoie;

canoinoaaiiy aioei?e?iaieo ?icniieooaaeueieo ie?aie i?e oi?ioaaii?
i?ia?aiiaaii? eaia?inoiie.

Oa?aeoa? ieaiiaeo iia?aoeaieo ao?o/aiue i?e ae?aceia?e oai?ia? oeoiea oa
12-iaei? eeoee aoa ianooiiei: ?acaeoe?y oeoiea ca A?eue?io ?? (14
aeiaaee?a), ?acaeoe?y oeoiea ca A?eue?io 11 a iiaeeo?eaoe??
Aioiaenoa?a-O?inoa?a?a (20), Aaeea?-Aaeueoo?a (23), ?o (8), ?acaeoe?y
oeoiea ca Iae?-Oae?iiaei (13), ia aeeeth/aiiy (6), oi?ioaaiiy
aano?iaioa?iaianoiiico (6), ?acaeoe?y oeoiea c aano?iaioa?iaianoiiicii
ca A?oaanueeei (6), naeaeoeaia i?ieneiaeueia aaaioii?y c ae?aioth/ith
iia?aoe??th ca O?iaai (8), AEaaoeaai (6), i?ei?iieanoeeith ca
Aaeiaea-Ieeoe?/ai (15) oa aeoiaeaiiieanoeeith ca Aeaeaaeii (5).
Anueiai 140 iia?aoeaieo a?o/aiue. Ne?ae a?aei?oeoe, ui oi?ioaaiiy
aano?iaioa?iaianoiiic?a oa oa?a ia 12-iae?e eeooe? i?iaiaeeeinue
aeeeth/ii iaeii?yaeiei aoceeeiaei na?icii-i?aeneeciaei oaii ieoeaie
Eai?iiaae AAeO, AA, Eai?ieiae. A 7 aeiaaeeao i?iaaaeaia aeiaeaoeiaa
aa?iaoecaoe?y «aaaeei?» eoene 12-iaei? eeoee aioei?e?iaiith
?icniieooaaeueiith iie?ia?iith ie?aeith (A?II) ia?ee ANAAA, ANAAAeO.

A?aoiaoth/e a?ieia?/i? iniaeeaino? ieoie Eai?iiaae IA, inoaii? aoee
aeei?enoai? i?e oi?ioaaii? aano?iaioa?iaianoiiico o 11 oai?eo noa?a/iai
oa iioeeiai a?eo, a oaeiae a 13 aeiaaeeao ?acaeoe?e oeoiea ca A-?? aeey
e?ea?aeaoe?? noaeiiiainiaaiiai oa aeaeiiiainiaaiiai i?ei?inoaiico.

O aeiaaeeao ?aeo oeoiea aoea aeeiiaia ?icoe?aia eiai ?acaeoe?y o 10
oai?eo c oi?ioaaiiyi aano?iaioa?iaianoiiico ca Aaeea?-Aaeueoo?ii,
oioaeueia aano?aeoii?y (8 oai?eo) c oi?ioaaiiyi no?aaio?aeii-eeoeiaiai
aianoiiico ca A?ey?iae/ai a iiaeeo?eaoe?? A. A. Oae?iiaa (6). O
/ioe?ueio oai?eo oe? aianoiiice aeiaeaoeiai aa?iaoeciaai? oa oe??ieai?
A?II. A aeaio aeiaaeeao aoa noi?iiaaiee no?aaio?aeii-eeoeiaee aianoiiic
ca Aa?aciaei-Iaoa?naiii. Aianoiiice aeiaeaoeiai oe??ieai? oa
aa?iaoeciaai? A?II. A 3 aeiaaeeao iaiia?aa?eueiino? ?aeo oeoiea aeeiiai?
aano?iaioa?iaianoiiice c aeiaeaoeiaei eeoeiaei aianoiiicai ca A?aoiii.
An? aeua caaaeai? aianoiiice oi?ioaaeenue iaeii?yaeiei oaii, ieoeith
Eai?iiaae IA.

Ieaiia? iia?aoeai? ao?o/aiiy ?c canoinoaaiiyi aioei?e?iaieo
?icniieooaaeueieo iie?ia?ieo iaoa??ae?a (A?II) ia iicaia/?ieiaeo
aeia/ieo oiaeao ia?aianee 102 oai?eo. ?c ieo, o 63 oai?eo aeeiiaia
oieaoeenoaeoii?y. Aeey caoeaaiiy eiaea aeia/iiai i?oo?a canoiniaai?
ieoee Eai?iiaae AA, AAeO, Eai?ieiae. A 4 aeiaaeeao, aea aa?iaoecaoe?y
eiaea aoea iaiiaeeeaa (aioo??oiueiia/?ieiaa ?icoaooaaiiy i?oo?a,
neea?icoaaiiy eiai no?iee) aa?iaoecaoe?y i?iaaaeaia A?II ia eeaeia?e
eiiiiceoe?? IE-7, IE-8. Aioei?e?iai? ?icniieooaaeuei? ieoee (A?I) aoee
canoiniaai? a 20 aeiaaeeao, oi?ioaaiiy oieaaeioiaeoiaeaiiaianoiiica ca
TH?aoai, a 6 aeiaaeeao oi?ioaaiiy oieaoeenoiaioa?iaianoiiica oa o 13
oai?eo aeey caoeaaiiy oieaaeioioii?/iiai ioai?o.

Ieaiia? iia?aoeai? ao?o/aiiy ia oiieiio oa oianoiio eeoa/ieeo ?c
canoinoaaiiyi A?I i?iaaaeai? c i?eaiaeo iooeei. Oae, o 4 oai?eo c
iooeeiith oiieiai eeoa/ieea aeeiiaia ?acaeoe?y o?aaeaiiai naaiaioa c
oi?ioaaiiyi iaeii?yaeiiai aioa?iaioa?iaianoiiica. Ia iooeeio oianoi?
eeoee i?iiia?iaaii 28 oai?eo. Noi?iiaaii 7 iaeiioa?iaeo
?eaio?ainaa?ciaianoiiic?a ii oeio «e?iaoeue a e?iaoeue» (2), aai «a?e a
a?e» (5) oa 21 oianoi-oianoieeoeia? aianoiiice ii oeio «e?iaoeue a
e?iaoeue». A on?o aeiaaeeao i?e oi?ioaaii? aianoiiic?a aoee aeei?enoai?
aeeeth/ii ieoee Eai?ieiae.

Ieaiiaa o??o?a?y ia?aaeiuei? /a?aaii? no?iee ?c canoinoaaiiyi A?I
aeeth/aea ianooii? iia?aoeai? ao?o/aiiy: iia?aoe?? ia a?eae? ia?aaeiuei?
/a?aaii? no?iee (44 oai?eo), ye? aeieeee i?ney ??ciiiai?oieo iia?aoe?e
ia i?aaiao /a?aaii? ii?iaeieie, o 4 iaoe??io?a ia ioieiao oa o 10 oai?eo
iaoiao a?eaeo. Oa?aeoa? iia?aoeaieo ao?o/aiue aoa oaeei: aa?i?iieanoeea
ca Naiaaeei, Iaei, AEa?a?o-Nianieoeionueeiio, Aan?i?, Iinoainueeiio. A?I
aoee canoiniaai? a 6 aeiaaeeao iia?aoe?e e?iiaea?iiieanoeee. O aeaio
iaoe??ioie iia?aoe?? e?iiaea?iiieanoeee ia?aaeoaaea iia?aoe?y oi?ioaaiiy
«iaeiai» oeoiea. Ie??i oeueiai, o 143 oai?eo A?I aoee aeei?enoai? aeey
caoeaaiiy ia?aaeiuei? /a?aaii? no?iee i?ney ieaiiaeo eaia?ioii?e.

A o?aaioi?e aaaeii?iaeuei?e o??o?a?? aeey iiia?aaeaeaiiy iani?iiiaeiino?
«aaaeei?» eoene o?iaaeiiiae?aiiai ia?inoea o 36 oai?eo aoea canoiniaaia
eiia?iaoe?y A?I c A?II. Oae, i?ney aiaiaeaeoii?? eoena ia?eoii?coaaeanue
ie?aieie aoceeeiaeie na?icii-i’ycaaeie oaaie (ieoea Eai?ieiae) a e?i?y
oa?a aeiaeaoeiai aa?iaoecoaaeanue oa oe??iethaaeanue ie?aeaie ANAAA,
ANAAAeO.. Aeey e?aui? o?enaoe?? ie?aee ia ?? e?a? iaiineeanue iaaee/ia
eeaeiaa eiiiiceoe?y IE-7 aai IE-8.

A aeno?ai?e o??o?a?? iicaia/?ieiaeo oiae?a A?II aoee canoiniaai? o 74
oai?eo. ?c ieo, a 52 aeiaaeeao c?iaeaia oieaoeenoaioii?y, o 10 oai?eo
oieaoeenoaeoii?y aoea ii?aeiaia c oieaaeioioii??th, a o 12 iaoe??io?a c
oieaaeioiaeoiaeaiiaianoiiicii ca TH?aoai. A 65 aeiaaeeao aeey
iiia?aaeaeaiiy caiaeueieo oneeaaeiaiue eiaea aeia/iiai i?oo?a caoeoi
ieoeith Eai?ieiae. O 9 oai?eo o ca’yceo ?c iaiiaeeea?noth aa?iaoecaoe??
eiaea aeia/iiai i?oo?a c-ca iae?ioe/ieo ci?i a na?ici?e iaieiioe?,
aa?iaoecaoe?y cae?eniaia A?II ia iaaee/i?e eeaeia?e eiiiiceoe?? IE-7.
Caoeaaiiy oieaaeioioii?/ieo ioai??a, oi?ioaaiiy a?e?iaeeaanoeaieo
aianoiiic?a i?iaaaeaii ieoeith Eai?ieiae. Ne?ae a?aei?oeoe, ui
oi?ioaaiiy aianoiiic?a aeeiioaaeinue o aiaieu? caiaeaiiy
(aeano?oeoeaiee oieaoeenoeo, ia?aaac?eoey?i? aanoeane).

A aeno?ai?e o??o?a?? oiiei? oa oianoi? eeoee c aeei?enoaiiyi A?II
i?iiia?iaaii 32 oai?eo, 19 oai?eo aoee iia?iaai? ia oe?
na?iciio?a?eiiciiai, 9 — o?a?eiiciiai, 4 iaoe??ioa —
o?a?eiicii-ai?eiiai ia?eoii?oo. I?e/eiaie ia?eoii?oo aoee: cauaieaia
a?eaea c iae?icii eeoee, iioeiaeaeaiiy eeoee, eeoeiaa iai?io?aei?noue,
oai?iaa E?iia, iacaioa??aeueiee o?iiaic, cauaieaiiy aeeaa?oeeoey Iaeeaey
a noaaiia?e a?eae?, A 9 aeiaaeeao iaiaaeeeenue aoeaaiiyi aeaoaeoo a
no?ioe? eeoee i?ney aen?/aiiy iaaeeoo?caeaoieo oeaiei. A ?ioeo aeiaaeeao
(23) aeeiiaia ?acaeoe?y oiiei? eeoee c oi?ioaaiiyi oiieieeoeiaeo
aianoiiic?a »a?e a a?e» (15 aeiaaee?a) aai «e?iaoeue a e?iaoeue (8
aeiaaee?a). Aeey iiia?aaeaeaiiy iani?iiiaeiino? oa?a oa aianoiiic?a aoea
canoiniaaia eiia?iaoe?y A?II. Oae, iaeii?yaei? na?icii-i?aeneecia? oae
oa aianoiiice noi?iiaai? ieoeith Eai?ieiae. I?ney naiaoe?? /a?aaii?
ii?iaeieie oa ?iooaaoe?? oiiei? eeoee e?i?y oa?a aa?iaoecoaaeanue oa
caoeuaeanue a?ae ?io?eoaaiiy ie?aeaie ANAAA aai ANAAAeO. Aeey e?aui?
o?enaoe?? ie?aie aei eeoee ia ?? e?a? iaiineee eeae IE-7. A 7 aeiaaeeao
i?iaaaeaii oi?ioaaiiy oiieieeoeiaeo aianoiiic?a iaeii?yaeiei
na?icii-i?aeneeciaei aoceeeiaei oaii ieoeith Eai?ieiae aac aeiaeaoeiai?
aa?iaoecaoe?? ciie aianoiiico A?II.

O 6 oai?eo A?II aoee aeei?enoai? aeey e?ea?aeaoe?? aeana?iciaaieo
iiaa?oiiue eeoee. O an?o oai?eo aeaoaeo na?iciiai iie?iao eeoee
ia?aaeuoaaa 5 ni. Iaeiiaoaii? iia?aoe?? i?e aino??e oianoieeoeia?e
iai?io?aeiino? iooeeiii? ao?ieia?? ?c canoinoaaiiyi A?II aeeiiaii o 16
oai?eo. A 5 aeiaaeeao iooeeia eieae?coaaeanue o ne?i?e eeooe?, a iaeiiio
a ia/?ieiaiio eoo?, o 4 iaoe??io?a a naeac?ieiaiio eoo? oa o 6 oai?eo a
neaiiaeaei?e eeooe?. Aeaee iia?aoeaieo ao?o/aiue aoee ianooiieie:
i?aaia?/ia aai?eieaeoii?y (6), e?aia?/ia aai?eieaeoii?y (8),
noaoioaeueia eieaeoii?y (2). Aeey iiia?aaeaeaiiy iani?iiiaeiino?
oiieioianoi- oa oianoioianoieeoeiaeo aianoiiic?a aoa ?ic?iaeaiee oa
aeei?enoaiee ianooiiee eiiieaen caoiae?a:

a) ca?eueiaiiy i?ieneiaeueiiai a?aeae?eo eeoa/ieea a?ae ai?noo;

a) oi?ioaaiiy aianoiiic?a aeai?yaeiei aoceeeiaei oaii ieoeith Eai?ieiae,
/ei aeinyaaeinue ciaioaiiy aaeoa??aeueiiai caa?oaeiaiiy oa?a;

a) o?ainaiaeueia oa iaciaano?aeueia ?iooaaoe?y oiieiai oa oianoiai
eeoa/ieea;

a) oe??ieaiiy ciie aianoiiico A?II ia iaaee/i?e eeaeia?e eiiiiceoe??
IE-7.

?c canoinoaaiiyi A?II i?iiia?iaaii 48 oai?eo c ia?oi?aoeaieie ae?aceaie
oeoiea oa 12-iaei? eeoee, o yeeo a?ae ii/aoeo caoai?thaaiiy i?ieoei
a?eueoa a aiaeei. O 28 aeiaaeeao oai?? aoee i?iiia?iaai? ia oe?
?iceeoiai na?iciiai ia?eoii?oo, 17 — o?a?eiiciiai, o 3 aeiaaeeao —
o?a?eiicii-ai?eiiai ia?eoii?oo. O 18 oai?eo aeeiiaii aen?/aiiy
ia?oi?aoeaii? ae?acee c i?ei?iieanoeeith ca Aaeiaea-I?eoe?/ai,
aeoiaeaiiieanoeea ca Aeaeaaeii-Oaiae? (7). O aeaio aeiaaeeao iia?aoe?y
aeiiiaiaia aeaia?/iith noiaao?iaith aaaioii??th, 5 — naeaeoeaiith oa o
18 oai?eo naeaeoeaiith i?ieneiaeueiith aaaioii??th. O an?o aeiaaeeao
i?ei?iieanoeee oa aeoiaeaiiieanoeee canoiniaoaaeenue ieoee Eai?ieiae, ca
aeiiiiiaith yeeo oi?ioaaany iaeii?yaeiee na?icii-i?aeneeciaee aoceeeiaee
oia. Caoeno oa aa?iaoecaoe?y oa?a i?iaiaeeeanue A?II. O 11 oai?eo i?e
ia?oi?aoe?? aaeeeeo eaeueicieo ae?acie aio?aeueiiai a?aeae?eo oeoiea
i?iaaaeaia eiai ?acaeoe?y ca A?eue?io 1 (4 aeiaaeee) oa ca A-?? (7) a
iiaeeo?eaoe?? Aaeea?-Aaeueoo?a. Aano?iaioa?i- oa aioa?iaioa?iaianoiiice
oi?ioaaee iaeii?yaeiei na?iciii?aeneeciaei oaii (ieoea Eai?ieiae),
aeiaeaoeiai aa?iaoecoaaee oa caoeuaee a?ae ?io?eoaaiiy A?II.

O 12 oai?eo c ia?oi?aoeaiith ae?aciith 12-iaei? eeoee, ye? iinooieee a
o??o?a?/iee a?aeae?e o aaaeeiio noai? i?iaaaeaii caoeaaiiy
ia?oi?aoeaiiai ioai?o iaeii?yaeiei oaii (ieoea Eai?ieiae) c ianooiiith
aa?iaoecaoe??th oa oe??ieaiiyi A?II.

A?II canoiniaai? o 32 oai?eo, yeei i?iaaaeaii iia?aoeaia ao?o/aiiy ia
«aenio?» oeoieiai-eeoeiai? e?iaioa/?. O 21 oai?iai i?e/eiith e?iaioa/?
aoea ae?acea 12-iaei? eeoee, o 8 aeiaaeeao — ae?acea oeoiea oa 3 —
iooeeia oeoiea. I?e e?iaioa/? c ae?acee 12-iaei? eeoee aeeiiaii:
aen?/aiiy ae?acee, i?ei?iieanoeea, o?oieoey?ia aaaioii?y (3 oai?eo),
aen?/aiiy ae?acee 12-iaei? eeoee i?ei?i- aai aeoiaeaiiieanoeea c
naeaeoeaiith i?ieneiaeueiith aaaioii??th (18 oai?eo). I?e e?iaioa/? c?
oeoiea aaeaaaeenue aei aen?/aiiy ae?acee c o?oieoey?iith aaaioii??th ( 2
aeiaaeee), ?acaeoe?? oeoiea ca A-? (2 iaoe??ioa), ?acaeoe?? oeoiea ca
A-?? (4 oai?eo ), aei ?icoe?aii? ?acaeoe?? oeoiea c aianoiiicii ca
Aaeea?-Aaeueoo?ii ( 3 aeiaaeee ). O an?o oai?eo aeey oi?ioaaiiy
iaeii?yaeieo oa?a canoiniaaia ieoea c aioea?ioeeii oa ?aia?aioii
Eai?iiaae IA.

A 152 aeiaaeeao aeno?aieo iia?aoeaieo ao?o/aiue aeey caoeaaiiy
ia?aaeiuei? /a?aaii? no?iee aeei?enoaia ieoea Eai?ieiae. A 77 aeiaaeeao
i?iaaaeaii caoeaaiiy na?aaeeiieo eaia?ioiiieo ?ai, a 53 aeiaaeeao
eaia?ioiiieo ?ai i?ney oieaoeenoaeoii?e ?ic??cii ca Eioa?ii oa 22
eaia?ioiii? ?aie c ?ic??co ca Iae-Ao?iaai oa ca Eaiiaiaea?ii. I?e/eiaie
aeno?aieo eaia?ioii?e aoee aino?ee aeano?oeoeaiee aiaiaeeoeeo aac aai c
iaiaiaaeaiei i?noeaaei ia?eoii?oii, aino?ee ?iceeoee ia?eoii?o, aino?ee
aeano?oeoeaiee oieaoeenoeo aac aai c yaeuaie iaiaiaaeaiiai ia?eoii?oo,
aanoean /a?aaii? ii?iaeieie.

A 4 aeiaaeeao ieoea Eai?ieiae aoea canoiniaaia aeey caoeaaiiy
eaia?ioiiieo ?ai i?ney e?ea?aeaoe?? oiiei oa oianoieeoeiaeo ii?eoeue.

A?II naiino?eii aeei?enoai? o aeaio oai?eo, iia?iaaieo c i?eaiaeo
aiaa?iaiiai iaeeino?eae?aeueiiai ia?eoii?oo, i?e oi?ioaaii?
i?ia?aiiaaii? eaia?inoiie. Ie?aee i?aeeeaaeaeenue i?ae /anoie?e ?c
iine?aeiaii coeoeo iie?oei?a?i?eiaeo o?oaie.

?ACOEUeOAOE AeINE?AeAEAIIss OA ?O IAAIAI?AIIss

I?iaaaeaii aiae?c ?acoeueoao?a aenia?eiaioaeueieo aeine?aeaeaiue.
Anoaiiaeaii, ui ii ?ic?eai?e i?oeiino? aioei?e?iai? ?icniieooaaeuei?
ieoee aeaui iinooiathoueny nai?io i?ioioeio ?icniieooaaeuei?e ieooe?
Eai?iiaae (41,2 ( 0,1 Iuethoiia i?ioe 41,8 ( 0,2 Iuethoiia). Iaeiae, ii
i?oeiino? aoceeeiaiai niieo/aiiy, iaea?eueo aaaeeea?e o i?aeoe/iiio
a?aeiioaii? aaee/eie A?I ia?aaaaeathoue Eai?iiaae o an?o oiiaieo iiia?ao
(34,3 ( 0,1 Iuethoiia i?ioe 33,7 ( 0,2 Iuethoiia ). Aioei?e?iai? ieoee
cia/ii e?aua o?eiathoue aocie. Oae, i?e caa’ycoaaii? ieoie Eai?iiaae A
niiniaii 1 o 1 o 1 iaae?ei?noue aocea neeaaea? 97%, a oie aea /an
oeae iieaciee aeey ieoee Eai?iiaae aei??aith? 88%. Caaaeyee iie?ia?iiio
iie?eooth coneeey ii i?ioyaoaaiith ieoie Eai?iiaae A a ii??aiyii? c
ieoeith Eai?iiaae ciaioo?oueny a 1,5 ?ace.

I?iaiae?ciaai? eai?ey?i? aeanoeaino? oa iayai?noue aoaeoo «aiioo» o
??cieo ia?ie ieoie Eai?iiaae A. sse iieacaee aei??thaaiiy, iaea?eueoa
eai?ey?i?noue a?aei?/aia o eai?iio — 354 ( 12,3 ii. A oie aea /an, o
ieoie oeio Eai?iiaae A aiia aoea cia/ii iaioith ( Eai?iiaae AA — 76,4 (
9,2 ii, Eai?iiaae AAeO — 53,5 ( 7,6 ii, Eai?ieiae — 51,2 ( 7,2 ii).
Anoaiiaeaii, ui eai?ey?i?noue ia caeaaeaea a?ae oiiaieo iiia??a ieoee.
I?ney aen?aaiiy c A?I ia aeaeoeai? na?aaeiaeua ?inoo i?ioay oa eeoeiai?
iaee/ee ia aeyaeaii. Oaeei /eiii, aioeaaeoa??aeuei? i?aia?aoe, ye?
ciaoiaeyoueny a no?oeoo?? iie?ia?iiai iie?eooy iiai?noth aeieothoue
?iciianthaeaeaiiy aaeoa??e ii aieieiai ieoee.

Aiae?c aeaieo c aeeiai?ee aeae?eaiiy eiaeo c iie?ia?iiai iie?eooy ieoee
Eai?ieiae iieacaa, ui /a?ac 6 aiaeei i?ney ?iieaioaoe?? ai?no eiaeo o
oeaiei? ia/?iee cia/iee — 0,118 iea/ie i?ioe 0,038 iea/ie a eiio?ie?
(ieoea Eai?iiaae ). *a?ac 12 aiaeei eiioeaio?aoe?y eiaeo ia?aaeuoaaea
eiio?ieuei? iieacieee a?eueoa i?ae o 5 ?ac?a ( 0,175 iea/ie i?ioe 0,034
iea/ie). Aei e?ioey ia?oi? aeiae oey ??cieoey ? ua a?eueo nooo?aith (
0,211 iea/ie i?ioe 0,029 a eiio?ie?). Iaeneiaeueia eiioeaio?aoe?y eiaeo
a oeaiei? ia/?iee a?aei?/aia ia o?aoth aeiao ( 0,451 iea/ie i?ioe 0,036
iea/ie a eiio?ie?). Aeniea eiioeaio?aoe?y eiaeo caa??aa?oueny aei 5
aeiae. I?e oeueiio, eiioeaio?aoe?y eiaeo 0,211 iea/ie ( 1 aeiaa i?ney
?iieaioaoe?? ) i?eai?/o? ??no i?e?ii?aai?ci?a aaea /a?ac aiaeeio a?ae
ii/aoeo ae??. Iiaia iiaeaaeaiiy ?inoo i?e?ii?aai?ci?a a?aei?/aii i?e
eiioeaio?aoe?? eiaeo 0,451 iea/ie. Oa?aeoa?ii oa, ui ia i?ioyc? ia?oi?
aeiae i?ney iia?aoe?? ??no i?e?ii?aai?ci?a i?aeoe/ii iiai?noth
i?eai?/o?oueny. Aei aeua caaaeaii? eiioeaio?aoe?? eiaeo aoee /ooeea?:
S.aureus, Proteus, Klebsiella, P.aeruqinosae, E.coli.

sse iieacaei aeine?aeaeaiiy aeeiai?ee ci?i aioeaaeoa??aeueieo
aeanoeainoae ieoie ia?ie Eai?iiaae AAeO, AA, IA — iaeneiaeueia
e?euee?noue aioeaaeoa??aeueieo i?aia?ao?a c iie?ia?iiai iie?eooy o
oeaieio aeaiaeeoueny ia i?ioyc? 24 aiaeei. Aeiaaio?eaae?noue
aioeaaeoa??aeueii? ae?? aeey ieoie Eai?iiaae AAeO neeaaea? 3 aeiae, aeey
Eai?iiaae AA — 4 aeiae, Eai?iiaae IA -5 ae?a. I?e oeueiio, a oeaiei?
noai?th?oueny eiioeaio?aoe?y aaioai?oeeio a?ae 4 aei 17 iea/ie,
ae?ieneaeeio a?ae 12,5 aei 37,5 iea/ie. Aei oeeo eiioeaio?aoe?e
aioeaaeoa??aeueieo i?aia?ao?a aoee /ooeea?: S.aureus, Proteus,
Klebsiella, P.aeruqinosae, E.coli.

I?iaaaeaii aiae?c aioeaaeoa??aeueieo aeanoeainoae ??cieo ia?ie Eai?iiaae
A in vitro ii a?aeiioaiith aei iniiaieo caoaeiee?a o??o?a?/ii? ?ioaeoe??
(S.aureus, Proteus, Klebsiella, P.aeruqinosae, E.coli.). Aiae?c
aeine?aeaeaiue iieacaa, ui an? ia?ee ieoie iathoue ae?aaeaio
aioeaaeoa??aeueio ae?th, iaeiae ieoee Eai?ieiae ii oeueiio iieacieeo
noiyoue iica eiieo?aioe??th. ?acoeueoaoe aeine?aeaeaiue nooiai?
eiioai?iaoe?? i?e?ioei?ith iiaa?oi? oianoieeoeiaeo oa?a c? noi?iie
na?icii? iaieiiee na?ae/eoue i?i oa, ui c ae?oai? aeiae i?ney iia?aoe??
?c ciie oa?a, noi?iiaaieo ieoeith Eai?ieiae aaeoa??? ia aen?aathoueny.
Aiaeia?/ia aaeoa??ieia?/ia ea?oeia a?aei?/aia ia 3-4 aeiao i?ney
iia?aoe?? a cii? oaa, noi?iiaaiiai ieoeaie Eai?iiaae AAeO, AA. A oie aea
/an, ia i?ioyc? anueiai ia??iaeo niinoa?aaeaiiy c eiio?ieueieo oa?a
(eai?iiiaa ieoea) aen?aa?oueny eeoeiaa oei?a. A?noiaaeoa??ieia?/ia
aeine?aeaeaiiy noaio aaeoa??aeueiiai caa?oaeiaiiy a?ey
aioeaaeoa??aeueieo ieoie i?aeoaa?aeaeo? ?o ae?aaeaio i?ioei?e?iaio
ae?th. Oae, yeui ia ia?oo aeiao a cii? oa?a, a iacaeaaeiino? a?ae aeaeo
oiaiiai iaoa??aeo niinoa??aa?oueny neoi/aiiy i?e?ii?aai?ci?a, oi ia
ae?oao aeiao a?ey ieoie Eai?ieiae cono??/athoueny eeoa iiiaeeiie?
iaee/ee oa eiee. Aiaeia?/ia aaeoa??ieia?/ia ea?oeia a?aei?/aia ia 3
aeiao a?ey ieoie Eai?iiaae AAeO. Ia 5 aeiao a ciiao aianoiiic?a,
noi?iiaaieo aioeaaeoa??aeueieie ieoeaie i?e?ii?aai?ci?a ia aeyaeaii. A
oie aea /an, a eiio?ieueieo aianoiiicao ( eai?iiiaa ieoea, ieoea
Eai?iiaae) a?aei?/a?oueny neoi/aiiy i?e?ii?aai?ci?a, a a ie?aieo
aeiaaeeao aiie niinoa??aathoueny a oiaiiio iaoa??ae?.

Aeai? iiaaiieiii?an?? ia?aeiieeai na?ae/aoue i?i ca?eueoaiiy iaoai?/ii?
i?oeiino? oa aa?iaoe/iino? oiieieeoeiaeo aianoiiic?a, caaaeyee
aeei?enoaiith A?I, Oae, yeui ia ia?oo aeiao i?ney iia?aoe??
aa?iaoe/i?noue aenia?eiaioaeueieo oa eiio?ieueieo aianoiiic? i?aeoe/ii
iaeiaeiaa ? neeaaea? 120-130 ( 5 ii.?o.no., oi ia 3 aeiao aa?iaoe/i?noue
eiio?ieueieo aianoiiic?a ciaioo?oueny ( 95-100 (5 ii.?o.no. — 0,93-0,96
eIa). A oie aea /an ia 3, 5, 7 aeiao aa?iaoe/i?noue aenia?eiaioaeueieo
aianoiiic?a caeeoa?oueny ia iiia?aaei?o oeeo?ao. Ia 10 aeiao i?ney
iia?aoe?? aa?iaoe/i?noue eiio?ieueieo oa aenia?eiaioaeueieo aianoiiic?a
ca?eueoo?oueny, iaeiae ??cieoey i?ae ieie caa??aa?oueny ( 170 — 180 ( 5
ii.?o. no. — 1,66 — 1,76 eIa i?ioe 150 -160 (5 ii.?o.no — 1,47 -1,57
eIa). Oaeei /eiii, caaaeyee canoinoaaiith A?I aaea?oueny ca?eueoeoe
aa?iaoe/i?noue oa iaoai?/io i?oei?noue eeoa/ieo aianoiiic?a.

Ii??aiyeueia ii?oieia?/ia ioe?iea caai?iiy eeoeiaeo aianoiiic?a,
noi?iiaaieo eai?iiiaith ieoeith, ?icniieooaaeueiith ieoeith Eai?iiaae oa
??cieie ia?eaie aioei?e?iaieo ?icniieooaaeueieo ieoie ( Eai?iiaae AAeO,
Eai?iiaae IA, Eai?ieiae) iieacaea, ui ia ia?oo aeiao i?ney iia?aoe??
ii?oieia?/i? ci?ie a cii? aianoiiic?a iia’ycai? c iia?aoe?eiith
o?aaiith. Aea a?aei?/aia a?eueo ae?aaeaia caiaeueia ?aaeoe?y a
aianoiiicao, ye? noi?iiaai? eai?iiiaith ieoeith oa ieoeith Eai?iiaae. Ia
3 aeiao i?ney iia?aoe?? caiaeueiee i?ioean a ae?eyieao eiio?ieueieo
aianoiiic?a iineeth?oueny. *?oei aecia/a?oueny oi?ioaaiiy i?e?iaanoean?a
a?ey ieoie. Ii?oieia?/ia ea?oeia aianoiiic?a, noi?iiaaieo
aioeaaeoa??aeueieie ieoeaie a ye?niiio ieai? a?ae??ciy?oueny. Ee?oeiia
?aaeoe?y i?i?iaeueia, a?aei?/aii iineaaeaiiy yaeu aenoaeaoe?? a?ey
ieoie, a?aeaoaa?oueny cia/ia caoaeaiiy aeaia?eaoe?eiiai aaeo. Ii e?i??
aianoiiico aecia/a?oueny neoi/aiiy ieoie o?a?eio. A?eueo oiai, a
aianoiiicao, ye? noi?iiaai? ieoeith Eai?iiaae IA /?oei aecia/athoueny
e?oae? ii?iaeieie aiaeioae?ioeeo?a, ye? na?ae/aoue i?i ii/aoie ?icaeoeo
iieiaei? a?aioeyoe?eii? oeaieie. Oi?ioaaiiy i?e?iaanoean?a a?ey ieoie ia
aeyaeaii. Ia 5 aeiao i?ney iia?aoe?? a eiio?ieueieo aianoiiicao /?oei
aecia/athoueny caiaeuei? ci?ie, ae?aaeaiee caiaeueiee ?io?eueo?ao a?ey
oiaiiai iaoa??aeo. Eaeeioeeoe, e?ioioeeoe, ieaciioeeoe ?ynii
?io?eueo?othoue aieieia ieoie. A?ey ieoie a i’ycia?e iaieiioe?
niinoa??aathoueny i?e?iaanoeane, ye? iioe?ththoueny aei neeciai?
iaieiiee. A cii? aenia?eiaioaeueieo aianoiiic?a ee?oeiia ?io?eueo?aoe?y
ye?nii i?iy?oueny. Ii?yae c iii??iith e?ioioeeoa?iith ?io?eueo?aoe??th
aeyaey?oueny aaeeea e?euee?noue o?a?iaeano?a oa o?a?ioeeo?a, e?euee?noue
yeeo aeaui a?eueoa a aianoiiicao, noi?iiaaieo ieoeith Eai?iiaae IA,
Ianooia? «i/euaiiy» neeciai? iaieiiee a?ae iae?ioe/ieo ian oa caiiaiaiiy
aeaoaeo?a iieiaeith a?aioeyoe?eiith oeaieiith, c’yaeythoueny
iiaiooai?ai? eai?ey?e. Ii e?i?? eiioaeoo oaa oi?iothoueny eieaaaiia?
o?a?eee. I?i?iaeueia ee?oeiia ?io?eueo?aoe?y ieoie, ui na?ae/eoue i?i
«caoenio» ae?th iie?ia?iiai iie?eooy.

Ia 7 aeiao i?ney iia?aoe?? a eiio?ieueieo aianoiiicao a?aei?/a?oueny
aeieeiaiiy aaaaoi? ia noaeeie a?aioeyoe?eii? oeaieie o aeaeyae?
a?aioeueii, c’yaeythoueny iiiaeeiie? o?a?eee. Niieo/iioeaieiiee oyae a
cii? noeeo — ?eoeee, oe?ieee. I?ae aieieiaie oiaiiai iaoa??aeo
i?iieeathoue o aaeee?e e?eueeino? ee?oeie niieo/ii? oeaieie oa aace?/
ee?oei ?icniieooaaiiy /oaeeo o?e. A aenia?eiaioaeueieo aianoiiicao i?oa
c? noi?iie neeciai? iaieiiee i?aeoe/ii iiai?noth ai?oae?co?oueny.
Ii/eia?oueny oi?ioaaiiy caeic neeciai? iaieiiee. A?ey ieoie Eai?iiaae IA
oi?io?oueny oiiea eainoea c o?a?ioeeo?a oa i?aeieo eieaaaiiaeo aieieii.

Iiiaeeiie? o?a?ici? oyae? ii/eiathoue i?iieeaoe a oiauo iie?ia?iiai
iie?eooy oiaiiai iaoa??aeo.

*a?ac 14 ae?a i?ney iia?aoe?? a?ey ieoie eai?ii oa Eai?iiaae
caa??aa?oueny caiaeueia ?aaeoe?y c iayai?noth iae?ioaa?a, eaeeioeeo?a oa
aaeeei? e?eueeino? a?aaionueeeo ee?oei. A ie?aieo aeiaaeeao iiaeeco
oiaiiai iaoa??aeo a?aei?/a?oueny ai?eia ?io?eueo?aoe?y. C? noi?iie
neeciai? iaieiiee aianoiiice iiai?noth ai?oae?ciaai? iaeiioa?iaei
ieineei ai?oae??i, oi/a a i?aeneeciaiio oa?? caa??aa?oueny noaeeiia
?aaeoe?y oa iaa?ye. A aenia?eiaioaeueieo aianoiiicao eiinie?aeaoe?y
no?iie eeoee i?aeoe/ii cae?i/aia. Ee?oeiia ?aaeoe?y — i?i?iaeueia,
c’yaeythoueny a?eo?ioeeoe o i?ina?o? iiaiooai?aieo noaeei. Ieoee
caieioo? o oiieo, u?eueio niieo/iioeaieiio eainoeo, a?ae yei? a aeeaeio
ieoie i?iieeathoue o?a?ici? io/ee. Iie?ia?ia iie?eooy aecia/a?oueny
ie?aieie o?aaiaioaie.

Oaeei /eiii, ?aaaia?aoeaiee i?ioean a aianoiiicao, noi?iiaaieo
aioeaaeoa??aeueieie ?icniieooaaeueieie ieoeaie, iniaeeai Eai?iiaae IA,
cia/ii aeia?aaeaea? oaeee aea o aianoiiicao, noi?iiaaieo eai?iiiaith
ieoeith oa ieoeith Eai?iiaae. A?eueo oiai oeae i?ioean, ca ?aooiie
aioeaaeoa??aeueii? ae?? ieoie iaaeeaea?oueny aei anaioe/iiai.

Aei e?ioey ia?oiai i?nyoey niinoa??aa?oueny iinooiiaa i?eai?/aiiy
ai?eiiai caiaeaiiy iaaeiei ieoie eai?ii oa Eai?iiaae, ?ieainoeyoe?y
ia?oi?. A?aei?/a?oueny i?i?inoaiiy a no?oeoo?o ieoee Eai?iiaae niieo/ii?
oeaieie, yea ae?eeoue ?? ia o?aaiaioe. A aenia?eiaioaeueieo aianoiiicao
caiaeueia ?aaeoe?y a?aenooiy. Iie?ia?ia iie?eooy ieoie ia aecia/a?oueny.
Ii/eia?oueny aeoeaia o?aaiaioaoe?y ieoie. A?ey ieo niinoa??aa?oueny
a?aaionuee? ee?oeie ?icniieooaaiiy noi?iii?o o?e, ye? i?eeiathoue
o/anoue a ?aci?aoe?? aeano?oeooth/eo /anoei ieoee.

*a?ac 3 i?nyoey i?ney iia?aoe?? a aianoiiicao, noi?iiaaieo eai?iiiaeie
ieoeaie, i?iaeiaaeo? aeaa??oe a’yeee caiaeueiee i?ioean. Eieaaaiic
cia/ii a?aenoa? a?ae aianoiiic?a noi?iiaaieo aioeaaeoa??aeueieie
ieoeaie. I?e aeei?enoaii? ieoee Eai?iiaae a?aei?/aii caoeoaiiy
caiaeueiiai i?ioeano oa ii/aoie ooai?aiiy eieaaaio o cii? noeeo
aianoiiico, a?aeiiaeththoueny no?oeoo?e neeciai? iaieiiee.
I?iaeiaaeo?oueny o?aaiaioaoe?y ieoee Eai?iiaae oa ?? iinooiiaa
?aci?aoe?y. A aenia?eiaioaeueieo aianoiiicao a?aei?/aii caaa?oaiiy
?oaoethaaiiy ia noeeao aianoiiic?a. I?ioean aeano?oeoe??
aioeaaeoa??aeueieo ieoie a?eueo ae?aaeaiee i?ae o ieoie oeio Eai?iiaae.

*a?ac 6 i?nyoe?a o a?eueoino? eiio?ieueieo aianoiiic?a a?ey ieoee eai?ii
oo?eio?oueny iacia/ii ae?aaeaiee caiaeueiee i?ioean A cii? aianoiiic?a,
noi?iiaaieo ieoeith Eai?ii, aecia/a?oueny eieaaaiiaee ?oaaoeue, a
oeaio?? yeiai niinoa??aathoueny aieieia ieoee. A aianoiiicao,
noi?iiaaieo aioeaaeoa??aeueieie ?icniieooaaeueieie ieoeaie nooo?ai?
??cieoe? c iiia?aaei?i no?ieii ia aeyaeaii. Ia i?noe? oiaiiai iaoa??aeo
aecia/a?oueny i?aeiee niieo/iioeaieiiee ?oaaoeue, a oeaio?? yeiai
aea-ia-aea cono??/athoueny caeeoee oiaiiai iaoa??aeo. *a?ac 7 i?nyoe?a
i?ney iia?aoe?? a ae?eyieao ?icoaooaaiiy eai?iiiai? ieoee i?iaeiaaeo?
aeaa??oe iacia/ii ae?aaeaiee caiaeueiee i?ioean. Eieaaaiiaee ?oaaoeue —
a?oaee, iane/aiee ee?oeiieie aeaiaioaie oa noaeeiaie. Ia i?noe?
?icoaooaaiiy ?icniieooaaeueiiai iaoa??aeo aecia/a?oueny i?aeiee
niieo/iioeaieiiee ?oaaoeue, caeeoie aieieii ia ciaeaeaii.

Oaeei /eiii, iiaia a?iaeano?oeoe?y aioeaaeoa??aeueieo ?icniieooaaeueieo
ieoie ianooia? ia 210 aeiao i?ney ?iieaioaoe??.

Aeey aecia/aiiy aoaeoeaiino? canoinoaaiiy A?II i?iaaaeaii aiae?c
i?neyiia?aoe?eieo oneeaaeiaiue a o?ueio a?oiao oai?eo ( iniiai?e oa
eiio?ieuei?e). A?oie noi?iiaai? ca nooiaiai aaeoa??aeueii?
caa?oaeiaiino? /a?aaii? ii?iaeieie. ? a?oia — oai??, ye? ia?aianee
»/eno?» iia?aoeai? ao?o/aiiy — ieaiia? aa?i?iieanoeee
e?iiaea?iiieanoeee, II a?oia — oai??, yeei i?iaaaeaii «oiiaii-/eno?»
iia?aoeai? ao?o/aiiy ia oeoieo oa 12-iae?e eeooe?, aeia/iiio i?oo?o oa
ciai?oi?o aeia/aaeo oeyoao, aeno?ai? ao?o/aiiy i?e e?iaioa/ao c? oeoiea
oa 12-iaei? eeoee, i?e cauaieai?e a?eae? aac iae?ico eeoa/ieea, ??cieo
aeaeao eeoeiai? iai?io?aeiino? aac ?acaeoe?? eeoee, i?inoiio
aiaiaeeoeeo?. III a?oia — oai??, ye? aoee i?iiia?iaai? a oiiaao
caa?oaeiaii? /a?aaii? ii?iaeieie — an? ieaiia? iia?aoeai? ao?o/aiiy ia
oiie?e oa oiano?e eeooe?, ye? cae?i/oaaeenue aeaeaeaiiyi ae?eyiee
eeoa/ieea, e?ea?aeaoe?y e?aaoo?ieo oa eeoeiaeo ii?eoeue, iia?aoeai?
ao?o/aiiy, aeeiiai? ia oe? ia?eoii?oo.

Aeey c?o/iino? aiae?co an? i?neyiia?aoe?ei? oneeaaeiaiiy iiae?eaii ia
aea? eaoaai???: oneeaaeiaiiy ai?eii-caiaeueiiai oa?aeoa?o oa
oneeaaeiaiiy, ye? iia’ycai? c aeei?enoaiiyi oiaiiai iaoa??aeo. Aei
ia?oi? eaoaai??? oneeaaeiaiue a?aeianee: caiaeuei? ?io?eueo?aoe oa
aanoeane /a?aaii? ii?iaeieie, caiaeuei? ?io?eueo?aoe oa iaaii?iiy
ia?aaeiuei? /a?aaii? no?iee. A ae?oao eaoaai??th oneeaaeiaiue aa?eoee:
e?aaoo?i? ii?eoe?, e?aaoo?iee oieae?o?ac, aianoiiiceoe oa aeaoi?iaoe?y
aianoiiic?a, oiai? a?aioeueiie, iani?iiiaei?noue aianoiiic?a.
I?neyiia?aoe?eiee ia?aa?a eiio?iethaaany caaaeueiiee?i?/ieie oa
?ino?oiaioaeueieie (o?a?iaano?iaeoiaeaiineii?y, eieiiineii?y,
oeueo?acaoeiaa aeine?aeaeaiiy ), ?aioaaiieia?/ieie iaoiaeaie.

Aiae?c i?neyiia?aoe?eiiai ia?aa?ao a 1 a?oi? oai?eo iieacaa ui oeiiaei
oneeaaeiaiiyi a eiio?ieuei?e a?oi? ? caiaeuei? ?io?eueo?aoe ?ai (7 — 14%
) oa iaaii?iiy ?ai ( 2 — 4% ), e?aaoo?i? ii?eoe? (11 aeiaaee?a — 22%). A
oie aea /an a iniiai?e a?oi? oai?eo ia a?aei?/aii iaaii?iiy ?ai oa
e?aaoo?ieo ii?eoeue, cia/ii iaioa e?euee?noue ( 3 — 6,5% ) caiaeueieo
?io?eueo?ao?a.

II a?oia oai?eo. Aiae?c oneeaaeiaiue i?ney iia?aoe?e ia oeoieo oa
12-iae?e eeooe? a eiio?ieuei?e a?oi? oai?eo iieaco?, ui iniiaiei
oneeaaeiaiiyi ?aiiueiai i?neyiia?aoe?eiiai ia??iaeo ? aaaeoaoi?i?
ii?ooaiiy c eoene oeoiea ca ?aooiie ?icaeoeo aianoiiiceo?a ( 7 aeiaaee?a
— 7,8% i?ioe 5 — 3,3% a iniiai?e a?oi?). Caaaeueiiee?i?/i? iaoiaee
ianoaaeaiiy aeyaeee, ui a eiio?ieuei?e a?oi? oai?eo, ia a?aei?io a?ae
iniiaii?, i?neyiia?aoe?eiee ia?aa?a o ia?aaaaeii? a?eueoino? oai?eo
noi?iaiaeaeoaaany no?eeei noaoaa?ee?oaoii oa iii??iei eaeeioeeoicii, ui
ia iaoo, aeoieo na?ae/eoue i?i caiaeueio ?aaeoe?th a ae?eyioe?
aianoiiico oa ooai?aiiy caiaeueiiai ?io?eueo?aoo a?ey iueiai. Iayai?noue
inoaiiueiai anoaiiaethaaee i?e iaeueiaoi?iiio oa OCAe ianoaaeaii? ( 4 —
5,7%). A iniiai?e a?oi? oai?eo caiaeueieo ?io?eueo?ao?a ia aeyaeaii. I?e
aiaeineii?/iiio aeine?aeaeai? o cia/ii? e?eueeino? oai?eo eiio?ieueii?
a?oie, a i?ciueiio i?neyiia?aoe?eiiio ia??iae? ( 1-3 i?nyoe?) aeyaeaii
o?ii?/iee caiaeueiee i?ioean, yeee aeiaaio?eaaeee /an i?aeo?eiothoue
e?aaoo?e. A ie?aieo oai?eo oiai? a?aioeueiie ciaoiaeeee ia i?ioyc?
1,5-2 ?ie?a ( 2 aeiaaeee ). A 4 aeiaaeeao o?ii?/iee caiaeueiee i?ioean a
cii? aianoiiico cae?i/eany eiai aeaoi?iaoe??th. A iniiai?e a?oi? /a?ac
1.5 — 2 i?nyoe? i?ney iia?aoe?? aiaeineii?/ii aoei aaaeei aecia/eoe
e?i?th aianoiiico. Oiai? e?aaoo?e, caiaeuei? yaeua c aieo neeciai?
iaieiiee ia niinoa??aaeenue.

Ii??aiyeueiee aiae?c i?neyiia?aoe?eiiai ia?aa?ao a eiio?ieuei?e a?oi?
oai?eo, ye? ia?aianee ieaiia? iia?aoeai? ao?o/aiiy ia ciai?oi?o aeia/ieo
oeyoao iieacaa, ui a?i oa?aeoa?eco?oueny no?eeei noaoaa?ee?oaoii, a
aeayeeo aeiaaeeao i?aeaeuaiiyi oaiia?aoo?e a?eueoa 38( N,
eaeeioeeoa?ieie ci?iaie a e?ia?. O 11% oai?eo iaeueioaaany caiaeueiee
?io?eueo?ao a i?aa?e i?ae?aaa?i?e ae?eyioe? ??cieo ?ici???a.
?aioaaiieia?/ieie iciaeaie caiaeueiiai i?ioeano aoee: iaiaaeaiiy
?ooiiino? ae?ao?aaie oa iacia/iee aei?o a einoaae?ao?aaiaeueiiio neion?.
I?e OCAe eiio?ie? a?aei?/aii iayai?noue aenoaeaoo a i?aeia/?ieiaiio
i?inoi??. Niinoa??aaeinue a?aeoiaeaeaiiy aeia/? /a?ac ciai?oi? ae?aiaae?
i?ioyaii 3-7 ae?a ( 5 aeiaaee?a oi?ioaaiiy a?e?iaeeaanoeaiiai aianoiiico
— 8%). E?aaoo?i? eiie?aiaioe eiinoaoiaaii o 4 oai?eo ( 6,4%), ye?
ia?aianee iia?aoeai? ao?o/aiiy ia ciai?oi?o aeia/ieo oiaeao. A iniiai?e
a?oi? i?neyiia?aoe?eiee ia??iae ia?aa?aaa ia oii? iacia/ii ae?aaeaii?
caiaeueii? ?aaeoe??. O 1 oai?iai (1,4%) aeyaeaii caiaeueiee ?io?eueo?ao
a i?aa?e i?ae?aaa?i?e ae?eyioe?. O ia?aaaaeii? a?eueoino? oai?eo
i?aeo?eaiiy aeia/? /a?ac ae?aiaae? ia aeyaeaii. A i?ciueiio
i?neyiia?aoe?eiiio ia??iae? e?aaoo?iiai oieae?o?aca ia niinoa??aaee.

I?iaaaeaii ii??aiyeueiee aiae?c i?neyiia?aoe?eieo oneeaaeiaiue o oai?eo,
ye? aoee iia?iaai? c i?eaiaeo cauaieaieo a?eae aac iae?ico eeoa/ieea,
??cieo aeaeao eeoeiai? iai?io?aeiino? aac ane?eooy i?ina?oo eeoa/ieea,
i?inoiio aiaiaeeoeeo?. A?I aeei?enoiaoaaeenue aeey caoeaaiiy
eaia?ioiiieo ?ai, aa?i?iieanoeee. I?e oeueiio anoaiiaeaii, ui a iniiai?e
a?oi? oai?eo cia/ii iaioa e?euee?noue caiaeueieo ?io?eueo?ao?a
ia?aaeiuei? /a?aaii? ( 1 aeiaaeie i?ioe 4 a eiio?ieuei?e a?oi?). A
aeayeeo aeiaaeeao (2) o oai?eo eiio?ieueii? a?oie ianooieei iaaii?iiy
?ai. A iaeiiio aeiaaeeo iaaii?iiy ?ai cae?i/eeinue iiaiith
aaaioa?aoe??th, a o iaeiiai oai?iai ooai?aiiyi i?neyiia?aoe?eii?
aaio?aeueii? a?eae?. O 3 oai?eo ae?aaiinoiaaii iiiaeeiie? oa iiiaeeii?
e?aaoo?i? ii?eoe?. A iniiai?e a?oi? aeua caaaeai? oneeaaeiaiiy ia
cono??/aeenue.

III a?oia oai?eo. Eiinoaoiaaii cia/ia ca?eueoaiiy e?eueeino?
ai?eii-caiaeueieo oa «oiaieo» oneeaaeiaiue. Oae, e?euee?noue aeiaaee?a
?io?eueo?ao?a oa aanoean?a /a?aaii? ii?iaeieie a eiio?ieueiee a?oi?
oai?eo neeaaea? 12 (9,2%) oa 4 (3,1), a ?io?eueo?ao?a oa iaaii?iue ?ai
a?aeiia?aeii 23 aeiaaeee (18%) oa 2 (1,5%). A 3 aeiaaeeao eiinoaoiaaii
iani?iiiaei?noue oa?a (2,3%), a aeaio — aianoiiiceo (1,5%). Iane?aeeii
caiaeueieo ?io?eueo?ao?a oa iaaii?iue ?ai noaei ooai?aiiy aeiaaio?eaaeeo
ooieoe?iioth/eo e?aaoo?ieo ii?eoeue ( 8 %). A oie aea /an, canoinoaaiiy
aioei?e?iaii? ?icniieooaaeueii? ieoee Eai?ieiae naiino?eii aai a
eiia?iaoe?? c A?II cia/ii ciaioo? e?euee?noue i?neyiia?aoe?eieo
oneeaaeiaiue. Oae, a iniiai?e a?oi? oai?eo aeyaeaii 7 ?io?eueo?ao? a
/a?aai?e ii?iaeiei?, ui neeaaea? 2,5% oa 9 ?io?eueo?ao?a ?ai (3,1%), 3
aeiaaeee aianoiiiceo?a (1%). Iaaii?iiy ?ai, aanoean?a /a?aaii?
ii?iaeieie, iani?iiiaeiino? oa?a, e?aaoo?ieo ii?eoeue ia niinoa??aaee.

I?e ni?aa?aeiioaii? ii e?eueeino? iia?aoe?eieo oneeaaeiaiue a aeaio
ia?oeo a?oiao oai?eo niinoa??aa?oueny iii?oia ??cieoey aeaieo a iniiai?e
oa eiio?ieuei?e a?oi?. Oae, yeui ai?eii-caiaeuei? oneeaaeiaiiy a
iniiai?e a?oi? neeaaeathoue eeoa 4 aeiaaeee (1,5%), oi a eiio?ieuei?e
a?oi? oey ??cieoey ae?inoa? aei 21 (11%). Ia iaioa ??cieoey aeyaeaia ii
e?eueeino? «oiaieo» oneeaaeiaiue — 8 ( 4%) a iniiai?e i?ioe 28 ( 15%) a
eiio?ieuei?e a?oi? oai?eo. Ua a?eueo iii?oia ??cieoey oeeo aeaieo
niinoa??aa?oueny a III a?oi?. A?aei?/aii cia/ia ca?eueoaiiy e?eueeino?
ai?eii-caiaeueieo oneeaaeiaiue a eiio?ieuei?e a?oi? — 39 aeiaaee?a ( 30%
). A oie aea /an iaia? nooo?aiai c?inoaiiy aeiaaee?a »oiaieo»
oneeaaeiaiue — 16 ( 12%). A iniiai?e a?oi? oaeiae a?aei?/aii ca?eueoaiiy
e?eueeino? ai?eii-caiaeueieo oneeaaeiaiue aei 16 aeiaaee?a ( 6%), iaeiae
??cieoey a oeeo oneeaaeiaiiyo a iniiai?e oa eiio?ieuei?e a?oi? — nooo?aa
( 6% i?ioe 30% ). Eiinoaoiaaia iecueea e?euee?noue «oiaieo»
oneeaaeiaiue a iniiai?e a?oi? (1%).

Caaaeueiee i?ioeaio oneeaaeiaiue ii o?ueii a?oiai oai?eo neeaaea?:

«oiai?» oneeaaeiaiiy i?e canoinoaaii? ia?icniieooaaeueiiai oiaiiai
iaoa??aeo — 13%;

ai?eii-caiaeuei? oneeaaeiaiiy i?e aeei?enoaii? A?II — 2%;

i?e aeei?enoaii? ia?icniieooaaeueiiai oiaiiai iaoa??aeo — 19%;

i?e canoinoaaii? A?II — 4,2%.

AENIIAEE

Aioei?e?iai? ?icniieooaaeuei? ieoee ii nai?i iai?ioeyoe?eiei oa
eai?ey?iei aeanoeainoyi, i?oeiino? ia ?ic?ea, aoceeeia?e i?oeiino?,
a?aeiia?aeathoue o?ceei-iaoai?/iei aeiiaai uiaei oiaiiai iaoa??aeo;

Ieoee iathoue ae?aaeaio aioei?e?iaio ae?th ia iniiai? caoaeieee
o??o?a?/ii? ?ioaeoe??;

I?e anaioe/iiio ia?aa?ao ?aiaaiai i?ioeano eiinie?aeaoe?y no?iie
aianoiiic?a, noi?iiaaieo ieoeaie Eai?iiaae A ianooia? ?ai?oa i?ae a
aianoiiicao, noi?iiaaieo eai?iiiaith ieoeith oa ?icniieooaaeueiith
ieoeith Eai?iiaae, ui aea? iiaeeea?noue ca?eueoeoe ?o a?ieia?/io
aa?iaoe/i?noue oa i?oei?noue o 1,5 ?ace;

Iiaia a?iaeano?oeoe?y ieoie ia?ie Eai?iiaae A caeaaeeoue a?ae ?o iiia?a
? ianooia? a ia??iae 180-210 ae?a;

O?ceei-iaoai?/i? oa aioeaaeoa??aeuei? aeanoeaino? ?icniieooaaeueieo
ieoie aeathoue iiaeeea?noue a ieaiia?e oa o?aaioi?e aaaeii?iaeuei?e
o??o?a?? a?aenooieoe a?ae o?aaeeoe?eii? iaoiaeeee oi?ioaaiiy oa?a ( 2-o
aai 3-o ?yaeiei ) ? oi?ioaaoe a?e?iaeeaanoeai? oa aeeaanoeai? aianoiiice
o?eueee iaeii?yaeiei oaii;

Canoinoaaiiy eiia?iaoe?? aioei?e?iaia ?icniieooaaeueia ieoea + iaaee/ia
eeaeiaa eiiiiceoe?y + aioei?e?iaia ?icniieooaaeueia ie?aea ? iaae?eiei
iaoiaeii iiia?aaeaeaiiy iani?iiiaeiino? oa?a oa aianoiiic?a, ui aea?
iiaeeea?noue ?icoe?eoe /ania? iaae? oa ia’?i iia?aoe?e ia oii?
ia?eoii?oo i?e ia?oi?aoeai?e ae?acoe? oeoiea oa 12-iaei? eeoee, ia
ciai?oi?o aeia/ieo oeyoao, oiie?e oa oiano?e eeooe?.

Iieacaie aei canoinoaaiiy ieoie ia?ie Eai?iiaae A ? :

ieoea Eai?iiaae AAeO — ieaiia? iia?aoeai? ao?o/aiiy ia i?aaiao /a?aaii?
ii?iaeieie, e??i iia?aoe?e ia oiano?e eeooe?;

ieoea Eai?iiaae IA — iia?aoeai? ao?o/aiiy, ye? aeeiiothoueny ia oii?
iiieaeaii? ?aia?aoeaii? caeaoiino? i?aai?cio;

ieoea Eai?ieiae — aaniethoiei iieacii aei canoinoaaiiy ? o?aaioi?
iia?aoeai? ao?o/aiiy ia i?aaiao /a?aaii? ii?iaeieie, caoeaaiiy
eaia?ioiiieo ?ai i?ney ?o aeeiiaiiy, ieaiia? iia?aoeai? ao?o/aiiy ia
oiano?e eeooe?;

eiia?iaoe?y ieoea Eai?ieiae — eeaeiaa eiiiiceoe?y — aioei?e?iaia
?icniieooaaeueia ie?aea — «aaaeea» eoena 12-iaei? eeoee oa aiaiaeeena,
caoeno a?ae ?io?eoaaiiy oa aa?iaoecaoe?y oa?a oa aianoiiic?a. ye?
ii?iothoueny ia oii? ia?eoii?oo.

Caaaeyee canoinoaaiith aioei?e?iaieo iie?ia?ieo ?icniieooaaeueieo
iaoa??ae?a a ieaiia?e oa o?aaioi?e aaaeii?iaeuei?e o??o?a?? aaeaeinue
ciaioeoe oneeaaeiaiiy ai?eii-caiaeueiiai oa?aeoa?e a 4,7 ?ace oa
oneeaaeiaiiy, ye? iia’ycai? c ye?noth oiaiiai iaoa??aeo o 6,5 ?ace.

I?AEOE*I? ?AEIIAIAeAOe??

A?aoiaoth/e iniaeeaino? eiaeiiai oeio aioeaaeoa??aeueieo
?icniieooaaeueieo ieoie aa/eii ianooii? iai?yiee ?o i?aeoe/iiai
aeei?enoaiiy:

A ieaiia? aaaeii?iaeuei?e o??o?a?? aeey ieoie ia?ee Eai?iiaae AAeO,
Eai?iiaae AA — oi?ioaaiiy ca ?o aeiiiiiaith aano?iaioa?i-,aioa?iaioa?i
oa a?e?iaeeaanoeaieo aianoiiic?a, ui aea? iiaeeea?noue nooo?ai ciaioeoe
e?euee?noue iani?iiiaeiino? oa?a, aianoiiic?a, aeaoi?iaoe?e aianoiiic?a,
oiaieo a?aioeueii, e?aaoo?iiai oieae?o?aco:

caoeaaiiy eaia?ioiiieo ?ai oa ieanoeea ia?aaeiuei? /a?aaii? no?iee, ui
aea? iiaeeea?noue ciaioeoe e?euee?noue ai?eii-caiaeueieo oneeaaeiaiue,
e?aaoo?ieo ii?eoeue;

ieoee ia?ee Eai?iiaae IA ne?ae aeei?enoiaoaaoe i?e neooaoe?yo, ye?
noi?iaiaeaeothoueny cieaeaiiyi ?aaaia?aoeaieo aeanoeainoae oeaiei;

a) iia?aoe?? c i?eaiaeo aano?iaeoiaeaiaeueieo e?iaioa/;

a) iia?aoeai? ao?o/aiiy c i?eaiaeo i?ei?inoaiic?a;

a) iia?aoe?? c i?eaiaeo iieicaoai?thaaiue oeoiea oa eeoa/ieea;

a) iia?aoeai? ao?o/aiiy ia i?aaiao o?aaiiai o?aeoo o ethaeae iioeeiai oa
noa?a/iai a?eo;

ae) iia?aoeai? ao?o/aiiy, ye? aeeiiothoueny ia oii? oeoe?iaiai ae?aaaoo.

Iieacaiiyie aeey canoinoaaiiy ieoie Eai?ieiae, a?aoiaoth/e ?o
oi?aa?naeueio i?ioei?e?iaio ae?th oa a?aenooi?noue caeeaiiy
i?e?ii?aai?ci?a aei eiaeo, anoaiiaeaii oae? o??o?a?/i? neooaoe??:

aeiaaeee iaa?aeeeaaeii? o??o?a??, aea c-ca c?icoi?eeo ianoaaei
?aeaioeo?eaoe?y i?e?ii?aai?ci?a oa ?o /ooeeaino? aei aioeaaeoa??aeueieo
i?aia?ao?a iaiiaeeeaa;

iaiao?aei?noue oi?ioaaiiy oa?a oa aianoiiic?a ia oeoieo, oiie?e oa
oiano?e eeooe? a oiiaao ia?eoii?oo;

caoeaaiiy eiaea aeia/iiai i?oo?a i?e aeano?oeoeaieo oi?iao aino?iai
oieaoeenoeoo, oi?ioaaiiy a?e?iaeeaanoeaieo aianoiiic?a a ?io?eiaai?e
/a?aai?e ii?iaeiei?;

ieaiia? iia?aoeai? ao?o/aiiy ia oiano?e eeooe?;

caoeaaiiy eaia?ioiiieo ?ai i?ney iia?aoeaieo ao?o/aiue ia oe?
ia?eoii?oo.

I?yieie iieacaie aei canoinoaaiiy eiia?iaoe?? aioei?e?iaii? ie?aee c
aioei?e?iaieie ?icniieooaaeueieie ieoeaie ? ?aaeeeaeuei? iia?aoeai?
ao?o/aiiy ia ii?iaeienoeo i?aaiao i?e ia?eoii?o?, «aaaeea» eoena
12-iaei? eeoee oa aiaiaeeena, aa?iaoecaoe?y eiaea aeia/iiai i?oo?a i?e
iaiiaeeeaino? oea c?iaeoe o?aaeeoe?eiei niiniaii.

Nienie iioae?eiaaieo i?aoeue ca oaiith aeena?oaoe??

Aiueinueeee A.A. Iia? i?aeoiaee aei o??o?a?/iiai e?eoaaiiy eeoeiai?
iai?io?aeiino? iooeeiiiai aaiaco // Aanoiee i?iaeai aeieiaee e
iaaeeoeeiu. – Oa?ueeia. – 1997. – ?8. – N.73-75.

Aiueinueeee A.A. Cia/aiiy aioeaaeoa??aeueiiai ?icniieooaaeueiiai oiaiiai
iaoa??aeo a iiia?aaeaeaii? i?ney?acaeoe?eieo neiae?ii?a // Ee?i?/ia
o??o?a?y. – 1997. — ?7-8. – N.44-45.

Aiueinueeee A.A. I?i aoaeoeai?noue canoinoaaiiy aioei?e?iaieo iie?ia?ieo
iaoa??ae?a a aaaeii?iaeuei?e o??o?a?? // A?niee iaoeiaeo aeine?aeaeaiue.
– 1998. — ?1-2 . – N.82-83.

Aiueinueeee A.A. Oeyoe aeei?enoaiiy aioei?e?iaieo ?icniieooaaeueieo
iie?ia?ieo iaoa??ae?a a aaaeii?iaeuei?e o??o?a?? // Oieoaeueia o??o?a?y
— 1998. — ?1. — N.33-35.

Aiueinueeee A.A. Canoinoaaiiy ?icniieooaaeueieo iie?ia?ieo iaoa??ae?a
aioei?e?iaii? ae?? a iaa?aeeeaaei?e o??o?a?? oeoiea oa 12-oe iaei? eeoee
// Ee?i?/ia o??o?a?y. – 1998. — ? 9. – N.

Aiueinueeee A.A. Canoinoaaiiy aioei?e?iaieo ieoie ? ie?aie o ieaiia?e ?
iaa?aeeeaaei?e aaaeii?iaeuei?e o??o?a?? // Aeooaeuei? i?iaeaie
iaa?aeeeaaeii? o??o?a?? i?aai?a /a?aaii? ii?iaeieie oa o?iaai?oaeueiiai
o?aeoo: Iaoa??aee ?anioae. iaoe. eiioa?. 21-22.10.96. – Ee?a. – 1996. –
N.149-150.

Aiueinueeee A.A. Ii??aiyeueia ii?oieia?/ia ioe?iea caai?iiy
oiieieeoeiaeo aianoiiic?a, noi?iiaaieo ??ciei oiaiei iaoa??aeii //
Iaoeia? caienee AIIIO. – Ee?a. – 1997. – /.?. – N.161-162.

Aiueinueeee A.A. ?icniieooaaeuei? neioaoe/i? iie?ia?i? iaoa??aee
oe?eani?yiiaaii? iaaee/ii? ae?? a aaaeii?iaeuei?e o??o?a?? // Caeiaooee
ee?i?/ii? oa aenia?eiaioaeueii? iaaeeoeeie: Iaoa??aee XI i?aenoieiai?
iaoeiai? eiioa?aioe??, i?enay/aii? 40-??/iiio tha?eath aeaaeai??. –
Oa?iii?eue. – 1997. – /.?. – N.301-304.

Aiueinueeee A.A. I?i iiaeeea?noue aeeiiaiiy iaeiiiiiaioieo a?aeiiaieo
iia?aoe?e i?e eeoeia?e iai?io?aeiino?, iaoiiaeai?e iooeeiiei i?ioeanii
// Aeooaeuei? ieoaiiy ee?i?/ii? ? aenia?eiaioaeueii? iaaeeoeeie: Oace
iaoe. eiio. – Oa?iii?eue. – 1994. — N. 142-143.

Aiueinueeee A.A. Iiia?aaeaeaiiy i?neyiia?aoe?eieo oneeaaeiaiue i?ney
oieaoeenoaeoii?? // Aeinyaiaiiy ? ia?niaeoeae ee?i?/ii? ?
aenia?eiaioaeueii? iaaeeoeeie: Oace iaoe. eiio. – Oa?iii?eue. – 1995. –
N.196-197.

Aiueinueeee A.A., Iaianothe A.E., Iaeueiaaiee A.A., Aeia?i?iaei?e A.A.
Aeei?enoaiiy iiaeo aioei?e?iaieo iie?ia?ieo iaoa??ae?a a o??o?a?/i?e
i?aeoeoe? // Iia? iaoiaee ae?aaiinoeee, e?eoaaiiy, i?io?eaeoeee: Oace
iaeanii? iaoeiai? eiioa?aioe??. – Oa?iii?eue. – 1989. – N.125-126.

Aiueinueeee A.A., A?eaaiei N.A. Canoinoaaiiy iiaiai oiaiiai iaoa??aeo o
o??o?a?? iicaia/eieiaeo oiae?a // Aeooaeuei? ieoaiiy o??o?a?? a na?oe?
iniaenoiai aeina?aeo: Oace Anaoe?a?inueeiai n-io o??o?a?a. – Oa?iii?eue.
– 1993. – N.65-66.

Aiueinueeee A.A., Eo?ei A.N. I?aaeoi?aaeaeaiea ianinoiyoaeueiinoe
“o?oaeiie” eoeueoe /a?aaia?aciiai io?inoea // Iaoa?eaee ? i?aeia?iaeiiai
eiia?ano c ?ioaa?aoe?eii? aio?iiieia??. — Oa?iii?eue. – 1995. –
N.125-126.

Aiueinueeee A.A., Eo?ei A.N. Ii?oieia?/ia ?aaeoe?y oeaieie ia iia?
?icniieooaaeuei? aioei?e?iai? iie?ia?i? ieoee // Iaoa??aee ?
i?aeia?iaeiiai eiia?ano c ?ioaa?aoe?eii? aio?iiieia??. – Oa?iii?eue. –
1995. – N.124-125.

Aiueinueeee A.A., Aecthaaiianueeee ?.ss. I?i i?aeaeuaiiy iaae?eiino?
oa?a oa aianoiiic?a ii?iaeienoeo i?aai?a a oiiaao ia?eoii?oo //
Aeooaeuei? i?iaeaie iaa?aeeeaaeii? o??o?a?? i?aai?a /a?aaii? ii?iaeieie
oa o?iaai?oaeueiiai o?aeoo: Iaoa??aee ?anioae?eainueei?
iaoeiai-i?aeoe/ii? eiioa?aioe??. – Ee?a. – 1996. – N.106.

Aiueinueeee A.A., Iieueia/ee A.?., Aieaea TH.I. Iiia?aaeaeaiiy
iani?iiiaeiino? oa?a oa aianoiiic?a ii?iaeienoeo i?aai?a a oiiaao
?io?eiaaii? /a?aaii? ii?iaeieie // No/ani? aniaeoe iaa?aeeeaaeii?
iaaee/ii? aeiiiiiae: Iaoa??aee iaoeiai-i?aeoe/ii? eiioa?aioe??,
i?enay/aii? 25-??//th e?ea?i? iaa?aeeeaaeii? aeiiiiiae. – Euea?a. —
1997. – N.

Aiueinueeee A.A., Eo?ei A.N. I?i iiaee ?icniieooaaeueiee oiaiee iaoa??ae
// Aanoiee i?iaeai aeieiaee e iaaeeoeeiu. – Oa?ueeia. – 1997. – ?8. –
N.73-75.

A?eaaiei N.A., Aiueinueeee A.A. Aenia?eiaioaeueia iaa?oiooaaiiy
canoinoaaiiy eiaeiai?noeeo oiaieo iaoa??ae?a o o??o?a?/i?e i?aeoeoe? //
Aeooaeuei? ieoaiiy o??o?a?? a na?oe? iniaenoiai aeina?aeo: Oace
Anaoe?a?inueeiai n-io o??o?a?a. – Oa?iii?eue. – 1993. – N.66-67.

Aeina?ae canoinoaaiiy aioei?e?iaieo niieo/ieo aeaiaio?a oa oiaieo
iaoa??ae?a o a?aeiiai?e o??o?a?? / Iieion TH.I., Aeaauaeia A.A., Aaeuo
N.E., Aiueinueeee A.A., A?eaaiei N.A. // Aeooaeuei? ieoaiiy o??o?a?? a
na?oe? iniaenoiai aeina?aeo: Oace Anaoe?a?inueeiai n-io o??o?a?a. –
Oa?iii?eue. – 1993. – N.44-45.

Canoinoaaiiy aioei?e?iaieo ieoie Eai?iiaae AeO, Eai?ieiae, Eai?iiaae IA
a o?aaioi?e oa ieaiia?e aaaeii?iaeuei?e o??o?a?? / Iieion TH.I.,
Aiueinueeee A.A., Aeia?i?iaei?e A.A., A?eaaiei N.A. // ?ioi?iaoe?eiee
eeno. – Ee?a. – 1994. – N.2.

Eo?ei A.N., Aiueinueeee A.A., E?aa/oe I.?. Ia?aeiii-aaia?aiiciee
aiaiaeeoeeo, ii?eoe? ne?ii? eeoee oa ?o caiia?aaiiy // No/ani? aniaeoe
iaa?aeeeaaeii? iaaee/ii? aeiiiiiae: Iaoa??aee iaoeiai-i?aeoe/ii?
eiioa?aioe??, i?enay/aii? 25-??//th e?ea?i? iaa?aeeeaaeii? aeiiiiiae. –
Euea?a. – 1996. – N.119.

Iieion TH.I., Aiueinueeee A.A., Iaianothe A.E. I?eiaiaiea
niaaeeieoaeueiuo aeiniaianoeiuo aioeiee?iaiuo yeaiaioia a eiiaeiaoeee n
eeaai IE-7, EE-3 a ieaiiaie e o?aaioiie oe?o?aee // I?eiaiaiea a
cae?aaio?aiaiee iieeia?iuo iaoa?eaeia e ecaeaeee ec ieo: Oac. aeiee.
Ananithci. naieia?a. – Iineaa. – 1985. – N.14-16.

Iieion TH.I., Aiueinueeee A.A., Iaianothe A.E. Aioeiee?iaiua iieeia?u a
o?aaioiie e ieaiiaie oe?o?aee // OO ieaioi Ananithci. iao/. ia-aa
oe?o?aia: Oac. aeiee. – Eueaia. – 1985. – N.167-168.

Iieion TH.I., Aiueinueeee A.A., Iaianothe A.E. I?eiaiaiea
aioeaaeoa?eaeueiuo iieeia?ia a eiiaeiaoeee n iaaeeoeeineeie eeayie aeey
oe?aieaiey oaia e aianoiiicia a ieaiiaie e o?aaioiie oe?o?aee //
Eioi?iaoeeiiiia ienueii. – Eeaa. –1987. – N.2.

Iieion TH.I., Aiueinueeee A.A., Aaeuo N.E. Ia?niaeoeau eniieueciaaiey
aioeaaeoa?eaeueiuo oiaiuo iaoa?eaeia a oe?o?aee // Ananithciay oeiea
«Iieeia?u e ecaeaeey ec ieo aeey iaaeeoeeiu; Nai?iee aeieeaaeia. —
Iineaa. -1998. — N.21-22.

Iieion TH.I., Aiueinueeee A.A. Aeei?enoaiiy iiaeo aioei?e?iaieo
iaoa??ae?a a oiiaao ?io?eiaaii? /a?aaii? ii?iaeieie // ?ioaineaia
oa?ai?y ? aoa?aioi? iaoiaee aeaoieneeaoe?? i?e ai?eii-naioe/ieo
caoai?thaaiiyo: Oace i?aeiaeanii? eiio. aianoac?ieia?a-?aai?iaoieia?a. –
Oa?iii?eue. – 1993. – N.45-46.

Iieion TH.I., Aiueinueeee A.A., A?eaaiei N.A. Iainiiaaiea i?eiaiaiey
eiaeiniaea?aeaueo ieoae a oe?o?ae/aneie i?aeoeea // Eeei. oe?o?aey. –
1993. – ?1. – N.49-50.

Iieion TH.I., Aiueinueeee A.A., A?eaaiei N.A. I?eiaiaiea ieoae Eai?iiaae
A, Eai?ieiae a oe?o?aee aiaia/?ii/iuo ae?e/iuo i?ioieia // Eeei.
oe?o?aey. – 1993. — ?1. – N.16-18.

Iieion TH.I., Aiueinueeee A.A., A?eaaiei N.A. I?eiaiaiea ieoae Eai?ieiae
a oe?o?aee ieuaaa?eoaeueiiai o?aeoa // Eeei. oe?o?aey. – 1994. — ?1-2. –
N.46-48.

Iieion TH.I., Aiueinueeee A.A., Iaianothe A.E. Aioeiee?iaiua
?annanuaathueany iieeia?iua iaoa?eaeu a i?ioeeaeoeea iineaiia?aoeuiiiuo
ineiaeiaiee a aaaeiieiaeueiie oe?o?aee // Iaaeeoeeineay oaoieea. — 1994.
— ?2. – N.45-46.

Iieion TH.I., Aiueinueeee A.A. Aeina?ae aeei?enoaiiy aioeaaeoa??aeueieo
iie?ia??a a ieaiia?e oa o?aaioi?e aaaeii?iaeuei?e o??o?a?? // ? C’?cae
o??o?a?a Oe?a?ie: Oace aeiiia?aeae. – Euea?a. – 1994. – N.423.

Iieion TH.I., Aiueinueeee A.A., Aeia?i?iaei?e A.A.Aeina?ae canoinoaaiiy
aioei?e?iaieo ?icniieooaaeueieo iie?ia?ieo iaoa??ae?a o o??o?a?/i?e
i?aeoeoe? // Ca??iee iaoeiaeo ?ia?o eaoaae?e oae. O??o?a??, i?enay/aieo
40-??//th Oa?iii?euenueei? iaaee/ii? aeaaeai??. – 1997. – Oa?iii?eue. –
N.21-27.

Aiioaoe?y

Aiueinueeee A.A.

Aioei?e?iai? ?icniieooaaeuei? iie?ia?i? iaoa??aee a ieaiia?e oa
o?aaioi?e aaaeii?iaeuei?e o??o?a??.

Aeena?oaoe?y ia caeiaoooy a/aiiai nooiaiy aeieoi?a iaaee/ieo iaoe ca
niaoe?aeuei?noth 14.01.03 — »O??o?a?y».

Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i. I.I.Aiaiiieueoey. Ee?a, 1998.

Aea/ai? o?ceei-iaoai?/i? aeanoeaino? iiaiai aioeaaeoa??aeueiiai oiaiiai
?icniieooaaeueiiai iaoa??aeo. Aenia?eiaioaeueii, ia 138 uo?ao oa 59
niaaeao aecia/aii aioei?e?iai? aeanoeaino? ieoie, aeeiai?eo aeae?eaiiy
aioeaaeoa??aeueieo i?aia?ao?a c iie?ia?iiai iie?eooy ieoee,
aa?iaoe/i?noue eeoa/ieo aianoiiic?a, noi?iiaaieo aioeaaeoa??aeueieie
?icniieooaaeueieie ieoeaie oa eai?iiiaith ieoeith. I?iaaaeaia
ii??aiyeueia ii?oieia?/ia oa?aeoa?enoeea ?aaaia?aoe?? a eeoa/ieo
aianoiiicao, noi?iiaaieo eai?iiiaith ieoeith, ?icniieooaaeueiith ieoeith
Eai?iiaae, ??cieie ia?eaie ?icniieooaaeueieo ieoie ( Eai?iiaae A, AeO,
Eai?iiaae IA, Eai?ieiae), aecia/aii oa?i?i a?iaeano?oeoe?? oeeo ieoie.

Ai?iaaoe?y aioei?e?iaieo iie?ia?ieo ?icniieooaaeueieo iaoa??ae?a (ieoie
oa ie?aie ANAAA, ANAAAeO) a ieaiia?e oa o?aaioi?e aaaeii?iaeuei?e
o??o?a?? i?iaaaeaia ia 545 oai?eo ??ciiai a?eo oa noao?. Aioei?e?iai?
?icniieooaaeuei? iie?ia?i? iaoa??aee aeei?enoai? i?e /enoeo,
oiiaii-/enoeo oa aaeoa??aeueia caa?oaeiaieo iia?aoeaieo ao?o/aiiyo.
Aioei?e?iai? ?icniieooaaeuei? ieoee naiino?eii aai a eiia?iaoe?? c
ie?aeith aoee canoiniaai? aeey oi?ioaaiiy aeeaanoeaieo oa
a?e?iaeeaanoeaieo iaeii?yaeieo aoceeeiaeo aianoiiic?a a ieaiia?e
o??o?a??, aa?i?iieanoeee aeey caoeaaiiy eaia?ioiiieo ?ai ( ieoee
Eai?iiaae AAeO, AA, IA), oi?ioaaiiy oa?a oa aianoiiic?a ia ii?iaeienoeo
i?aaiao ia oe? ia?eoii?oo, aaaee?e eoen? 12-iaei? eeoee, aiaiaeeena
(eiia?iaoe?y ieoea Eai?ieiae oa aioei?e?iaia ?icniieooaaeueia ie?aea)
aeey aa?iaoecaoe?? eiaea aeia/iiai i?oo?a.

Eiio?ieueiith a?oiith aoee 310 oai?eo, yeei aoee aeeiiai? aiaeia?/i?
iia?aoeai? ao?o/aiiy, aea c aeei?enoaiiy ia?icniieooaaeueiiai oiaiiai
iaoa??aeo.

Aiae?c aeaieo aenia?eiaioaeueieo aeine?aeaeaiue iieacaa, ui
aioei?e?iaiee ?icniieooaaeueiee iaoa??ae? ii nai?i o?ceei-iaoai?/iei
aeanoeainoyi a?aeiia?aea? aeiiaai, ye? noaaeyoueny aei
?icniieooaaeueiiai oiaiiai iaoa??aeo, iathoue i?i?iaeuei? eai?ey?i?
aeanoeaino?, a?aenooi?e aoaeo «aiioo», iathoue aioeaaeoa??aeueio ae?th
ia iniiai? caoaeieee o??o?a?/ii? ?ioaeoe??. I?e oi?ioaaii? eeoeiaeo
aianoiiic?a aioeaaeoa??aeueiei ?icniieooaaeueiei ieoeai, i?oei?noue
inoaii?o ca?eueoo?oueny a 1,5 ?ace. Caaaeyee aioeaaeoa??aeueiiio
?icniieooaaeueiiio oiaiiio iaoa??aeo ?aaaia?aoeai? i?ioeane a cii?
aianoiiic?a aeia?aaeaeathoue oae? ae nai?, a aianoiiicao, noi?iiaaieo
eai?iiiaith ieoeith oa ?icniieooaaeueiith ieoeith Eai?iiaae, ?
iaaeeaeathoueny aei anaioe/iiai. ?icniieooaaiiy ieoie ianooia? ia 310
aeiao i?ney iia?aoe??.

Ii??aiyeueiee aiae?c i?neyiia?aoe?eieo oneeaaeiaiue a iniiai?e oa
eiio?ieuei?e a?oi? iieacaa, ui caaaeyee aeei?enoaiith aioeaaeoa??aeueieo
iie?ia?ieo ?icniieooaaeueieo iaoa??ae?a aaeaeinue ciaioeoe e?euee?noue
ai?eiicaiaeueieo oneeaaeiaiue a 4,7 ?ace oa oneeaaeiaiiy, ye? iia’ycai?
c ye?noth oiaiiai iaoa??aeo a 6,5 ?ace.

Eeth/ia? neiaa: Aaaeii?iaeueia o??o?a?y, i?neyiia?aoe?ei?
oneeaaeiaiiy, aioei?e?iai? ?icniieooaaeuei? iie?ia?i? iaoa??aee.

Aiiioaoeey

Aiueineee A.A.

Aioeiee?iaiua ?annanuaathueany iieeia?iua iaoa?eaeu a ieaiiaie e
o?aaioiie aaaeiieiaeueiie oe?o?aee.

Aeenna?oaoeey ia nieneaiea o/aiie noaiaie aeieoi?a iaaeeoeeineeo iaoe
ii niaoeeaeueiinoe 14.01.03 — «Oe?o?aey».

Iaoeeiiaeueiue iaaeeoeeineee oieaa?neoao ei. I.I.Aiaiiieueoea., Eeaa,
1998.

Eco/aiu oeceei-iaoaie/aneea naienoaa iiaiai aioeaaeoa?eaeueiiai
?annanuaathuaainy oiaiiai iaoa?eaea. Yenia?eiaioaeueii, ia 132 e?unao e
59 niaaeao ii?aaeaeaiu aioeaaeoa?eaeueiua naienoaa ieoae, aeeiaieeo
auaeaeaiey aioeaaeoa?eaeueiuo i?aia?aoia ec iieeia?iiai iie?uoey ieoee,
aa?iaoe/iinoue eeoa/iuo aianoiiicia, noi?ie?iaaiiuo aioeaaeoa?eaeueiuie
?annanuaathueieny ieoeaie e eai?iiiaie ieoeie. I?iaaaeaia n?aaieoaeueiay
ii?oieiae/aneay oa?aeoa?enoeea ?aaaia?aoeee a eeoa/iuo aianoiiicao i?e
oi?ie?iaaiee eo eai?iiiaie ieoeie, ?annanuaathuaeny ieoeie Eai?iiaae,
?acee/iuo ia?ie aioeiee?iaiuo ?annanuaathueony ieoae (Eai?iiaae AAeO,
Eai?iiaae IA, Eai?ieiae), ii?aaeaeai oa?iei aeiaeano?oeoeee yoeo ieoie.

Ai?iaaoeey aioeiee?iaiuo ?annanuaathueony iieeia?iuo iaoa?eaeia ( ieoae
e ieaiie ANAAAeO, ANAAA) a ieaiiaie e o?aaioiie oe?o?aee i?iaaaeaia ia
545 aieueiuo ?acee/iiai aic?anoa e iiea. Aioeiee?iaiua ?annanuaathueany
iieeia?iua iaoa?eaeu eniieueciaaiu ai a?aiy auiieiaiey /enoua
oneiaii-/enouo, aaeoa?eaeueii caa?yciaiiuo iia?aoeaiuo aiaoaoaeuenoaao.
Aioeiee?iaiua ?annanuaathueany ieoee naiinoiyoaeueii eee a eiiaeiaoeee n
ieaieie i?eiaiaiu aeey oi?ie?iaaiey aeeaanoeaiuo e aeeeiaeeaanoeaiuo
iaeii?yaeiuo oceiauo oaia, aianoiiicia, aa?ieiieanoeea aeey caoeaaiey
eaia?ioiiiuo ?ai (ieoee Eai?iiaae AAeO, AA, IA) aeey oi?ie?iaaiey oaia e
aianoiiicia ia iieuo i?aaiao ia oiia ia?eoiieoa, «oyaeaeie» eoeueoa
12-ia?noiie eeoee, aiiaiaeeena aeey aa?iaoecaoeee eiaea aeae/iiai iocu?y
( eiiaeiaoeey ieoea Eai?ieiae n aeoeiee?iaiie ?annanuaathuaeny ieaieie).
Eiio?ieueiie a?oiiie auee 310 aieueiuo, eioi?ui i?iaaaeaiu aiaeiae/iua
iia?aoeaiua aiaoaoaeuenoaa ii n eniieueciaaieai ia?annanuaathuaainy
oiaiiai iaoa?eaea. Aiaeec aeaiiuo yenia?eiaioaeueiuo enneaaeiaaiee
iieacae, /oi aioeiee?iaiue ?annanuaathueeny iaoa?eae ii naiei
oeceei-iaoaie/aneei naienoaai ioaa/aao o?aaiaaieyi, eioi?ua
i?aaeuyaeythony e ?annanuaathuaiony oiaiiio iaoa?eaeo, iaeaaeaao
ieieiaeueiuie eaieeey?iuie naienoaaie, o iaai ionoonoaoao yooaeo
«oeoeey», ii ieacuaaao aioeaaeoa?eaeueiia aeaenoaea ia iniiaiua
aicaoaeeoaee oe?o?ae/aneie eioaeoeee. I?e oi?ie?iaaiee eeoa/iuo
aianoiiicia aioeaaeoa?eaeueiuie ?annanuaathueieny ieoeaie i?i/iinoue
aianoiiicia oaaee/eaaaony a 1,5 ?aca. Aeaaiaea?y eniieueciaaieth
aioeaaeoa?eaeueiiai oiaiiai iaoa?eaea ?aaaia?aoeaiua i?ioeannu
iia?aaeatho oaeea aea i?ioeannu a aianoiiicao noi?ie?iaaiiuo eai?iiiaie
ieoeie e ?annanuaathuaeny ieoeie Eai?iiaae.

N?aaieoaeueiue aiaeec iineaiia?aoeeiiiuo ineiaeiaiee a iniiaiie e
eiio?ieueiie a?oiia iieacae, /oi aeaaiaea?y i?eiaiaieth aioeiee?iaiuo
?annanuaathueony iieeia?iuo iaoa?eaeia oaeaeinue oiaiueoeoue eiee/anoai
aiieii-ainiaeeoaeueiuo ineiaeiaiee a 4,7 ?aca, ineiaeiaiee naycaiiuo n
ea/anoaii oiaiiai iaoa?eaea a 6,5.

Eeth/aaua neiaa: Aaaeiieiaeueiay oe?o?aey, iineaiia?aoeeiiiua
ineiaeiaiey, aioeiee?iaiua ?annanuaathueany iieeia?iua iaoa?eaeu.

The summary

Goshchinsky V.B.

Antimicrobic resolving polymeric materials in planned and urgent
surgery.

The dissertation for the degree of a doctor of medical sciences in
speciality 14.01.03. — «Surgery».

National medical university named after O. Bogomoltzia. Kyyiv, 1998.

Physical and mechanical properties of a new antibacterial resolving
suture material have been carried out.

Antibacterial properties of sutures, educing dynamics of antibacterial
preparations from polymeric covering of the sutures and hermeticness of
intentional anastomosis formed by means of antibacterial resolving
sutures and capron ones have been defined experimentally on 138 rats and
59 dogs.

Comparative morphological characteristics of the influence on the
regeneration process by its formation with the help of a capron suture,
resolving suture Capromed, different kinds of antimicrobic resolving
sutures such as Capromed ADX Capromed MG, Caproyod has been carried
out, the term of biodistruction of these sutures has been defined as
well.

The approbation of antimicrobic resolving polymeric materials (sutures
and films ECAAAeO, ANAAA) has been carried out during both planned and
urgent surgery on 545 patients of different age and sex. The
antimicrobic resolving polymeric materials were used during pure,
conditionally pure, and bacterially polluted surgical interventions.

The antimicrobic resolving sutures were used independently on in the
combination with a corresponding antimicrobic resolving film for
formation digestive and bellyodigestic monolined knot stitches
anastomosises, hermoplastic sewing up lapartomic wounds (Capromed ADX,
AG, MG sutures) forming stitches and anastomosises on hollow organs on
the background of peritonitonits, hard stumy of duodenum, appendix,
hermetization of the bed of gall-bladder (combination of capromed suture
with antimicrobic resolving film).

The control groop included 310 patients who underwent analogical
surgical interventions with using resolving suture materials.

The analysis of the bindings of the experimental research showed that
antimicrobic materials in their physical-mechanical propertics satisfy
the demands as to resolving suture materials, possess minimum capppilar
propertics, have great antimicrobic influence on main patogenic
organisms which provoke surgical infections.

The comparative analysis of post surgical complications in the main and
control groups proved that thank to the usage of antimicribic resolving
polymeric materials it was possible to decrease supperative-inflamed
complications by 4,7 times and complications connected with the quality
of the suture material by 6,5 times.

Key word: Abdominal surgery, post surgical complications, antimicrobic
resolving polymeric materials.

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